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PEDİATRİK DİŞ HEKİMLİĞİNDE LEZYON STERİLİZASYONU VE DOKU TAMİRİ

Year 2022, Volume: 8 Issue: 1, 27 - 41, 28.04.2022

Abstract

Çocuk diş hekimliğinin temel amacı, süt dişlerini eksfoliyasyon zamanına kadar sağlıklı bir şekilde ağızda tutmaktır. Süt dişleri, estetik, fonasyon, çiğneme fonksiyonlarını sağlamalarının yanı sıra dental arkta yer tutucu görevi de görmektedir. Süt dişi çürüklerinin hızlı ilerlemesi nedeniyle genellikle endodontik tedavi ya da çekim söz konusudur. Son dönemde yapılan çalışmalar, lezyon sterilizasyonu ve doku tamiri LSTR  lezyon sterilizasyonu ve doku tamiri  konsepti çerçevesinde, çeşitli antibiyotik patların kök kanal bakteri eliminasyonu sağladığını göstermiştir. Bu sayede konak bağışıklığı ile doku tamiri oluşmakta ve çekim ertelenebilmektedir.
Klinik çalışmalar, LSTR tedavisinin klinik ve radyolojik olarak başarılı olduğu göstermiştir. Bu nedenle, kooperasyon güçlüğü olan hastalarda kısa sürede ve kolay uygulanabilen alternatif bir tedavi seçeneği sunmaktadır.

References

  • 1. American Academy of Pediatric Dentistry. Management of the developing dentition and occlusion in pediatric dentistry. The Reference Manual of Pediatric Dentistry. Chicago, Ill.: American Academy of Pediatric Dentistry; 2021:408-25.
  • 2. Lin YJ, Lin YT. Long-term space changes after premature loss of a primary maxillary first molar. J Dent Sci. 2017 Mar;12(1):44-48.
  • 3. Pedersen J, Stensgaard K, Melsen B. Prevalence of malocclusion in relation to premature loss of primary teeth. Community Dent Oral Epidemiol. 1978 Jul;6(4):204-9.
  • 4. Folayan MO, Arije O, El Tantawi M, Kolawole KA, Obiyan M, Arowolo O, Oziegbe EO. Association between early childhood caries and malnutrition in a sub-urban population in Nigeria. BMC Pediatr. 2019 Nov 13;19(1):433.
  • 5. Nadelman, P., Bedran, N., Magno, M. B., Masterson, D., de Castro, A., & Maia, L. C. (2020). Premature loss of primary anterior teeth and its consequences to primary dental arch and speech pattern: A systematic review and meta-analysis. International journal of paediatric dentistry, 30(6), 687–712.
  • 6. Souza, J., Souza, S. E., Noronha, M., Ferreira, E., & Martins, A. (2018). Impact of untreated dental caries on the daily activities of children. Journal of public health dentistry, 78(3), 197–202.
  • 7. Moskovitz, M., Sammara, E., & Holan, G. (2005). Success rate of root canal treatment in primary molars. Journal of dentistry, 33(1), 41–47.
  • 8. Duarte, M.L., Pires, P.M., Ferreira, D.M., Pintor, A.V., de Almeida Neves, A., Maia, L.C., & Primo, L.G. (2020). Is there evidence for the use of lesion sterilization and tissue repair therapy in the endodontic treatment of primary teeth? A systematic review and meta-analyses. Clinical Oral Investigations, 24, 2959 - 2972.
  • 9. Takushige, T., Cruz, E. V., Asgor Moral, A., & Hoshino, E. (2004). Endodontic treatment of primary teeth using a combination of antibacterial drugs. International endodontic journal, 37(2), 132–138.
  • 10. Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. International endodontic journal. 1996;29(2):125-130.
  • 11. Sain S, Reshmi J, Anandaraj S, George S, Issac JS, John SA. Lesion Sterilization and Tissue Repair–Current Concepts and Practices, Int J Clin Pediatr Dent. 2018;11(5):446-450.
  • 12. Burrus D, Barbeau L, Hodgson B. Treatment of abscessed primary molars utilizing lesion sterilization and tissue repair: literature review and report of three cases. Pediatric dentistry. 201415;36(3):240-244.
  • 13. Windley, W., 3rd, Teixeira, F., Levin, L., Sigurdsson, A., & Trope, M. (2005). Disinfection of immature teeth with a triple antibiotic paste. Journal of endodontics, 31(6), 439–443.
  • 14. Jaya AR, Praveen P, Anantharaj A, Venkataraghavan K, Rani PS. In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations. J Clin Pediatr Dent. 2012 Winter;37(2):189-91.
  • 15. Trairatvorakul C, Sastararuji T. Indirect pulp treatment vs antibiotic sterilization of deep caries in mandibular primary molars. Int J Paediatr Dent. 2014 Jan;24(1):23-31.
  • 16. Goswami S. Lesion sterilization and tissue repair in pediatric dentistry. SRM J Res Dent Sci 2018; 9:79-82.
  • 17. Shetty AA, Geethanjali G, Hegde AM. Lesion sterilization and tissue repair in primary teeth. SRM J Res Dent Sci. 2020; 11:99-105.
  • 18. Arangannal P, Muthiah G, Jeevarathan J, Sankar P. Lesion sterilization and tissue repair in nonvital primary teeth: An In vivo study. Contemp Clin Dent. 2019; 10:31-5.
  • 19. Tomar D, Dhingra A (2015) Nonsurgical Root Canal Therapy of Large Cystic Periapical Lesions Using Simple Aspiration and LSTR (Lesion Sterilization and Tissue Repair) Technique: Case Reports and Review. Dentistry 2015: 312.
  • 20. Beniwal P, Kalra N, Tyagi R, Khatri A. Pulp therapy of primary molars using lesion sterilization tissue repair and traditional endodontic treatment. Saudi J Oral Sci. 2020; 7:181-8.
  • 21. Lokade A, Thakur S, Singhal P, Chauhan D, Jayam C. Comparative evaluation of clinical and radiographic success of three different lesion strerilization and tissue repair techniques as treatment option in primary molars requiring pulpectomy: An in vivo study. J Indian Soc Pedod Prev Dent. 2019; 37:185-91.
  • 22. Agarwal M, Das UM, Vishwanath D. A compar-ative evaluation of noninstrumentation endodontictechniques with conventional ZOE pulpectomy in deciduous molars: An in vivo study. World J Dent. 2011; 2:187-92.
  • 23. Nakornchai S, Banditsing P, Visetratana N. Clinicalevaluation of 3Mix and Vitapex as treatment op-tions for pulpally involved primary molars. Int JPediatr Dent. 2010; 20:214-21.
  • 24. Dasari V, Maroli S, Chowdary L, Karukola R, Premakumar SH, Vusurumarthi V. An in vivo study evaluating lesion sterilization and tissue repair 3 MIX-MP noninstrumentation endodontic treatment as an alternative to conventional endodontic retreatment. CHRISMED J Health Res 2016; 3:284-7.
  • 25. Kayalvizhi G, Subramaniyan B, Suganya G. Topical application of antibiotics in primary teeth: an overview. Journal of Dentistry for Children. 201315; 80(2):71-79.
  • 26. Anila B, Murali H, Cheranjeevi J, Kapil RS. Lesion Sterilization and Tissue Repair (LSTR): A Review. J scientific dentistry. 2014:4(2)49-55.
  • 27. Cruz, E. V., Kota, K., Huque, J., Iwaku, M., & Hoshino, E. (2002). Penetration of propylene glycol into dentine. International endodontic journal, 35(4), 330–336.
  • 28. Prabhakar AR, Sridevi E, Raju OS, Satish V. Endodontic treatment of primary teeth using combination of antibacterial drugs: an in vivo study. J Indian Soc Pedod Prev Dent. 2008; 26:5-10.
  • 29. Kim, J. H., Kim, Y., Shin, S. J., Park, J. W., & Jung, I. Y. (2010). Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. Journal of endodontics, 36(6), 1086–1091.
  • 30. Parasuraman VR, Mujlibhai BS. 3 Mix MP in endodontics. An overview. IOSR J Dent Med Sci 2012; 3:36‑45.
  • 31. Bansal R, Jain A. Overview on the current antibiotic containing agents used in endodontics. N Am J Med Sci. 2014; 6:351‑8.
  • 32. Grewal N, Sharma N, Chawla S. Comparison of resorption rate of primary teeth treated with alternative lesion sterilization and tissue repair and conventional endodontic treatment: An in vivo randomized clinical trial. J Indian Soc Pedod Prev Dent. 2018; 36:262-7.
  • 33. Garcia C, Cruz E, Hoshino E, et al. 3Mix Lesion Sterilization and Tissue Repair (LSTR) therapy in extensive caries of deciduous teeth. The J Philippine Dental Assoc. 2004; 56:4-13.
  • 34. Sjögren U, Figdor D, Sundqvist G. Persistent periapical radiolucencies of root-filled human teeth, failed endodontic treatments and periapical scars. Oral Med Oral Pathol Oral Radiol Endod. 1999; 87:617-627
  • 35. Duanduan, Achiraya, Varisara Sirimaharaj, and Papimon Chompu-inwai. "Retrospective study of pulpectomy with Vitapex and LSTR with three antibiotics combination (3mix) for non vital pulp treatment in primary teeth". CMU J Nat Sci.12.2 (2013): 131-139.

LESION STERILIZATION AND TISSUE REPAIR IN PEDIATRIC DENTISTRY

Year 2022, Volume: 8 Issue: 1, 27 - 41, 28.04.2022

Abstract

The main purpose of pediatric dentistry is to keep the primary teeth healthy until exfoliation time. In addition to providing aesthetic, phonation and chewing functions, primary teeth also can act as space maintainers in the dental arch. Due to the rapid progression of caries in primary teeth, endodontic treatment or extraction is usually required. Recent studies have shown that various antibiotic pastes provide root canal bacterial elimination within the LSTR concept namely, “lesion sterilisation and tissue repair”. In this way, tissue repair occurs with host immunity, and tooth extraction can be delayed.
Clinical studies have reported that LSTR therapy is clinically and radiologically successful. For this reason, it offers an alternative treatment option for uncooperative patients that can be applied easily in dental setting within a short time.

References

  • 1. American Academy of Pediatric Dentistry. Management of the developing dentition and occlusion in pediatric dentistry. The Reference Manual of Pediatric Dentistry. Chicago, Ill.: American Academy of Pediatric Dentistry; 2021:408-25.
  • 2. Lin YJ, Lin YT. Long-term space changes after premature loss of a primary maxillary first molar. J Dent Sci. 2017 Mar;12(1):44-48.
  • 3. Pedersen J, Stensgaard K, Melsen B. Prevalence of malocclusion in relation to premature loss of primary teeth. Community Dent Oral Epidemiol. 1978 Jul;6(4):204-9.
  • 4. Folayan MO, Arije O, El Tantawi M, Kolawole KA, Obiyan M, Arowolo O, Oziegbe EO. Association between early childhood caries and malnutrition in a sub-urban population in Nigeria. BMC Pediatr. 2019 Nov 13;19(1):433.
  • 5. Nadelman, P., Bedran, N., Magno, M. B., Masterson, D., de Castro, A., & Maia, L. C. (2020). Premature loss of primary anterior teeth and its consequences to primary dental arch and speech pattern: A systematic review and meta-analysis. International journal of paediatric dentistry, 30(6), 687–712.
  • 6. Souza, J., Souza, S. E., Noronha, M., Ferreira, E., & Martins, A. (2018). Impact of untreated dental caries on the daily activities of children. Journal of public health dentistry, 78(3), 197–202.
  • 7. Moskovitz, M., Sammara, E., & Holan, G. (2005). Success rate of root canal treatment in primary molars. Journal of dentistry, 33(1), 41–47.
  • 8. Duarte, M.L., Pires, P.M., Ferreira, D.M., Pintor, A.V., de Almeida Neves, A., Maia, L.C., & Primo, L.G. (2020). Is there evidence for the use of lesion sterilization and tissue repair therapy in the endodontic treatment of primary teeth? A systematic review and meta-analyses. Clinical Oral Investigations, 24, 2959 - 2972.
  • 9. Takushige, T., Cruz, E. V., Asgor Moral, A., & Hoshino, E. (2004). Endodontic treatment of primary teeth using a combination of antibacterial drugs. International endodontic journal, 37(2), 132–138.
  • 10. Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. International endodontic journal. 1996;29(2):125-130.
  • 11. Sain S, Reshmi J, Anandaraj S, George S, Issac JS, John SA. Lesion Sterilization and Tissue Repair–Current Concepts and Practices, Int J Clin Pediatr Dent. 2018;11(5):446-450.
  • 12. Burrus D, Barbeau L, Hodgson B. Treatment of abscessed primary molars utilizing lesion sterilization and tissue repair: literature review and report of three cases. Pediatric dentistry. 201415;36(3):240-244.
  • 13. Windley, W., 3rd, Teixeira, F., Levin, L., Sigurdsson, A., & Trope, M. (2005). Disinfection of immature teeth with a triple antibiotic paste. Journal of endodontics, 31(6), 439–443.
  • 14. Jaya AR, Praveen P, Anantharaj A, Venkataraghavan K, Rani PS. In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations. J Clin Pediatr Dent. 2012 Winter;37(2):189-91.
  • 15. Trairatvorakul C, Sastararuji T. Indirect pulp treatment vs antibiotic sterilization of deep caries in mandibular primary molars. Int J Paediatr Dent. 2014 Jan;24(1):23-31.
  • 16. Goswami S. Lesion sterilization and tissue repair in pediatric dentistry. SRM J Res Dent Sci 2018; 9:79-82.
  • 17. Shetty AA, Geethanjali G, Hegde AM. Lesion sterilization and tissue repair in primary teeth. SRM J Res Dent Sci. 2020; 11:99-105.
  • 18. Arangannal P, Muthiah G, Jeevarathan J, Sankar P. Lesion sterilization and tissue repair in nonvital primary teeth: An In vivo study. Contemp Clin Dent. 2019; 10:31-5.
  • 19. Tomar D, Dhingra A (2015) Nonsurgical Root Canal Therapy of Large Cystic Periapical Lesions Using Simple Aspiration and LSTR (Lesion Sterilization and Tissue Repair) Technique: Case Reports and Review. Dentistry 2015: 312.
  • 20. Beniwal P, Kalra N, Tyagi R, Khatri A. Pulp therapy of primary molars using lesion sterilization tissue repair and traditional endodontic treatment. Saudi J Oral Sci. 2020; 7:181-8.
  • 21. Lokade A, Thakur S, Singhal P, Chauhan D, Jayam C. Comparative evaluation of clinical and radiographic success of three different lesion strerilization and tissue repair techniques as treatment option in primary molars requiring pulpectomy: An in vivo study. J Indian Soc Pedod Prev Dent. 2019; 37:185-91.
  • 22. Agarwal M, Das UM, Vishwanath D. A compar-ative evaluation of noninstrumentation endodontictechniques with conventional ZOE pulpectomy in deciduous molars: An in vivo study. World J Dent. 2011; 2:187-92.
  • 23. Nakornchai S, Banditsing P, Visetratana N. Clinicalevaluation of 3Mix and Vitapex as treatment op-tions for pulpally involved primary molars. Int JPediatr Dent. 2010; 20:214-21.
  • 24. Dasari V, Maroli S, Chowdary L, Karukola R, Premakumar SH, Vusurumarthi V. An in vivo study evaluating lesion sterilization and tissue repair 3 MIX-MP noninstrumentation endodontic treatment as an alternative to conventional endodontic retreatment. CHRISMED J Health Res 2016; 3:284-7.
  • 25. Kayalvizhi G, Subramaniyan B, Suganya G. Topical application of antibiotics in primary teeth: an overview. Journal of Dentistry for Children. 201315; 80(2):71-79.
  • 26. Anila B, Murali H, Cheranjeevi J, Kapil RS. Lesion Sterilization and Tissue Repair (LSTR): A Review. J scientific dentistry. 2014:4(2)49-55.
  • 27. Cruz, E. V., Kota, K., Huque, J., Iwaku, M., & Hoshino, E. (2002). Penetration of propylene glycol into dentine. International endodontic journal, 35(4), 330–336.
  • 28. Prabhakar AR, Sridevi E, Raju OS, Satish V. Endodontic treatment of primary teeth using combination of antibacterial drugs: an in vivo study. J Indian Soc Pedod Prev Dent. 2008; 26:5-10.
  • 29. Kim, J. H., Kim, Y., Shin, S. J., Park, J. W., & Jung, I. Y. (2010). Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. Journal of endodontics, 36(6), 1086–1091.
  • 30. Parasuraman VR, Mujlibhai BS. 3 Mix MP in endodontics. An overview. IOSR J Dent Med Sci 2012; 3:36‑45.
  • 31. Bansal R, Jain A. Overview on the current antibiotic containing agents used in endodontics. N Am J Med Sci. 2014; 6:351‑8.
  • 32. Grewal N, Sharma N, Chawla S. Comparison of resorption rate of primary teeth treated with alternative lesion sterilization and tissue repair and conventional endodontic treatment: An in vivo randomized clinical trial. J Indian Soc Pedod Prev Dent. 2018; 36:262-7.
  • 33. Garcia C, Cruz E, Hoshino E, et al. 3Mix Lesion Sterilization and Tissue Repair (LSTR) therapy in extensive caries of deciduous teeth. The J Philippine Dental Assoc. 2004; 56:4-13.
  • 34. Sjögren U, Figdor D, Sundqvist G. Persistent periapical radiolucencies of root-filled human teeth, failed endodontic treatments and periapical scars. Oral Med Oral Pathol Oral Radiol Endod. 1999; 87:617-627
  • 35. Duanduan, Achiraya, Varisara Sirimaharaj, and Papimon Chompu-inwai. "Retrospective study of pulpectomy with Vitapex and LSTR with three antibiotics combination (3mix) for non vital pulp treatment in primary teeth". CMU J Nat Sci.12.2 (2013): 131-139.
There are 35 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section REVIEWS
Authors

Berk Şengüler This is me 0000-0003-0994-2021

Venus Seyedoskuyi

Gizem Akkuş This is me 0000-0002-9164-1713

Başak Akdağ This is me 0000-0003-1051-9802

Ekin Doğan This is me 0000-0002-1501-4945

Akif Aslantaş This is me 0000-0003-2171-673X

Aslı Topaloğlu Ak 0000-0003-4572-1875

Publication Date April 28, 2022
Submission Date February 23, 2022
Published in Issue Year 2022 Volume: 8 Issue: 1

Cite

Vancouver Şengüler B, Seyedoskuyi V, Akkuş G, Akdağ B, Doğan E, Aslantaş A, Topaloğlu Ak A. PEDİATRİK DİŞ HEKİMLİĞİNDE LEZYON STERİLİZASYONU VE DOKU TAMİRİ. Aydin Dental Journal. 2022;8(1):27-41.

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