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Quality of life and associated factors in hemodialysis and peritoneal dialysis patients

Year 2020, Volume: 45 Issue: 1, 79 - 88, 31.03.2020
https://doi.org/10.17826/cumj.628274

Abstract

Purpose: This study aimed to examine the quality of life (QOL) in hemodialysis (HD) and peritoneal dialysis (PD) patients. Additionally, associations between QOL and clinical and demographic factors were investigated.
Materials and Methods: Patients under dialysis treatment were included in this cross-sectional study. Demographic data, disease history, and laboratory data were collected. Charlson comorbidity index (CCl) was used to score the level of comorbidity. Health-related quality of life (HRQOL) was measured by Kidney Disease Quality of Life Short Form Version 1.3 (KDQOL-SF 1.3).
Results: One hundred and five patients, 60 of whom were under HD, and 45 were under PD (45.7% were females; mean age 54.63±13.86 years) were enrolled in the study. PD patients had better scores in five domains of the KDQOL-SF 1.3 questionnaire (emotional role, work status, cognitive function, dialysis staff encouragement, patient satisfaction). Older age, female sex, lower education level, high comorbidity score and, hospitalization in the last 12 months were found to be related to low QOL. We detected positive correlations between serum hemoglobin levels, albumin, and some subgroups of KDQOL-SF 1.3 scale; whereas negative correlations were detected between serum ferritin levels and some of the KDQOL-SF 1.3 items.
Conclusion: According to our study, HRQOL was better in PD patients compared to HD in specific domains of the KDQOL-SF 1.3. Age, gender, education level, hemoglobin level, albumin, and ferritin were associated with HRQOL. 

References

  • 1. Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis. Journal of American Society of Nephrology.2001;12:2797–2806.
  • 2. Grzegorzewska AE, Izdebska A, Niepolski L, Warchoł W, Jagodziński PP. Self-Reported Physical Activity, Quality of Life, and Psychological Status in Relation to Plasma 25-Hydroxyvitamin D Concentration in Patients Treated with Hemodialysis. Kidney Blood Press Res. 2016;41(6):886-900.
  • 3. Al Wakeel J, Al Harbi A, Bayoumi M, Al-Suwaida K, Al Ghonaim M, Mishkiry A.Quality of life in hemodialysis and peritoneal dialysis patients in Saudi Arabia. Ann Saudi Med. 2012;32(6):570-4.
  • 4. Bohlke M, Nunes DL, Marini SS, Kitamura C, Andrade M, Von-Gysel MP. Predictors of quality of life among patients on dialysis in Southern Brazil. Sao Paulo Med J. 2008;126(5):252-6..
  • 5. Zazzeroni L, Pasquinelli G, Nanni E, Cremonini V, Rubbi I .Comparison of Quality of Life in Patients Undergoing Hemodialysis and Peritoneal Dialysis: a Systematic Review and Meta-Analysis. Kidney Blood Press Res. 2017;42(4):717-727.
  • 6. Cleary J, Drennan J. Quality of life of patients on haemodialysis for end-stage renal disease. J Adv Nurs. 2005;51(6):577-86.
  • 7. National Kidney Foundation. KDOQI clinical practice guideline and clinical practice recommendations: hemodialysis adequacy, peritoneal dialysis adequacy, and vascular access: update 2006. Am J Kidney Dis. 2006;48(suppl 1):1-322.
  • 8. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–383.
  • 9. Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index.J Clin Epidemiol. 1994;47(11):1245-51.
  • 10. Hays RD, Kallich JD, Mapes DL, Coons SJ, Amin N, Carter WB. Kidney Disease Quality of Life Short Form (KDQOL- SF), Version 1.3:A manual for use and scoring. 1997. Available from: http://www.rand.org/pubs/papers/2006/P7994.pdf
  • 11. Yildirim A, Ogutmen B, Bektas G, Isci E, Mete M, Tolgay HI. Translation, cultural adaptation, initial reliability, and validation of the Kidney Disease and Quality of Life-Short Form (KDQOL-SF 1.3) in Turkey. Transplantation Proceedings. 2007; 39: 51-54.
  • 12. Alvares J, Cesar CC, Acurcio Fde A, Andrade EI, Cherchiglia ML. Quality of life of patients in renal replacement therapy in Brazil: comparison of treatment modalities. Qual Life Res. 2012;21(6):983-91.
  • 13. Mittal SK, Ahern L, Flaster E, Mittal VS, Maesaka JK, Fishbane S. Self-assessed quality of life in peritoneal dialysis patients. Am J Nephrol. 2001;21(3):215-20.
  • 14. Fructuoso M, Castro R, Oliveira L, Prata C, Morgado T. Quality of life in chronic kidney disease. Nefrologia. 2011;31(1):91-6.
  • 15. Okpechi IG, Nthite T, Swanepoel CR. Health-related quality of life in patients on hemodialysis and peritoneal dialysis. Saudi J Kidney Dis Transpl. 2013;24(3):519-26.
  • 16. de Abreu MM, Walker DR, Sesso RC, Ferraz MB. Health-related quality of life of patients recieving hemodialysis and peritoneal dialysis in São Paulo, Brazil: a longitudinal study. Value Health. 2011;14(5 Suppl 1):119-21.
  • 17. Molsted S, Prescott L, Heaf J, Eidemak I. Assessment and clinical aspects of health-related quality of life in dialysis patients and patients with chronic kidney disease. Nephron Clin Pract. 2007;106(1):24-33.
  • 18. Lopes GB, Martins MT, Matos CM, Amorim JL, Leite EB, Miranda EA et al. Comparisons of quality of life measures between women and men on hemodialysis. Rev Assoc Med Bras. 2007;53(6):506-9.
  • 19. Valderrábano F, Jofre R, López-Gómez JM. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38(3):443-64.
  • 20. Kimmel PL, Peterson RA, Weihs KL, Simmens SJ, Boyle DH, Verme D et al. Behavioral compliance with dialysis prescription in hemodialysis patients. J Am Soc Nephrol. 1995:1826-34.
  • 21. Harris LE, Luft FC, Rudy DW, Tierney WM. Clinical correlation of functional status in patients with chronic renal insufficiency. Am J Kidney Dis. 1993;21:161-6.
  • 22. Moreno F, Lo´pez Go´mez JM, Sanz Guajardo D, Jofre R, Valderra´bano F. Quality of life in dialysis patients. A spanish multicentre study. Spanish Cooperative Renal Patients Quality of Life Study Group. Nephrol Dial Transplant. 1996;11(2):125-9.
  • 23. Mielck A, Reitmeir P, Vogelmann M, Leidl R. Impact of educational level on health-related quality of life (HRQL): results from Germany based on the EuroQol 5D (EQ-5D). Eur J Public Health. 2013;23(1):45-9.
  • 24. Stojanovic M, Stefanovic V. Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income. Artif Organs. 2007;31(1):53-60.
  • 25. Zhang AH, Cheng LT, Zhu N, Sun LH, Wang T. Comparison of quality of life and causes of hospitalization between hemodialysis and peritoneal dialysis patients in China. Health Qual Life Outcomes. 2007;5:49.
  • 26. Moreno F, Sanz-Guajardo D, López-Gómez JM, Jofre R, Valderrábano F. Increasing the hematocrit has a beneficial effect on quality of life and is safe in selected hemodialysis patients. Spanish Cooperative Renal Patients Quality of Life Study Group of the Spanish Society of Nephrology. J Am Soc Nephrol 2000;11:335-42.
  • 27. Blake PG, Flowerdew G, Blake RM, Oreopoulos DG. Serum albumin in patients on continuous ambulatory peritoneal dialysis--predictors and correlations with outcomes. J Am Soc Nephrol. 1993;3(8):1501-7.
  • 28. Spiegel DM, Anderson M, Campbell U, Hall K,Kelly G, McClure E, Breyer JA. Serum albumin: A marker for morbidity in peritoneal dialysis patients. Am J Kidney Dis. 1993;21:26.
  • 29. Unruh M, Benz R, Greene T, Yan G, Beddhu S, DeVita M et al. HEMO Study Group. Effects of hemodialysis dose and membrane flux on health-related quality of life in the HEMO Study. Kidney Int. 2004;66(1):355-66.

Hemodiyaliz ve periton diyalizi hastalarında yaşam kalitesi ve ilişkili olduğu faktörler

Year 2020, Volume: 45 Issue: 1, 79 - 88, 31.03.2020
https://doi.org/10.17826/cumj.628274

Abstract

Amaç: Bu çalışmanın amacı hemodiyaliz (HD) ve periton diyalizi (PD) hastalarında yaşam kalitesini incelemektir. Ayrıca, yaşam kalitesi ile klinik ve demografik faktörler arasındaki ilişkiler incelenmiştir.
Gereç ve Yöntem: Diyaliz tedavisi alan hastalar bu kesitsel çalışmaya dahil edildi. Demografik veriler, hastalık öyküsü, laboratuvar verileri toplandı. Komorbidite seviyesini puanlamak için Charlson komorbidite indeksi (CCl) kullanıldı. Sağlıkla ilişkili yaşam kalitesi (SYK), Böbrek Hastalığı İlişkili Yaşam Kalitesi Kısa Form Versiyon 1.3 (KDQOL-SF 1.3) ile ölçülmüştür.
Bulgular: Çalışmaya 60'ı HD, 45'i PD tedavisi altında (% 45.7'si kadın; ort. yaş 54.63 ± 13.86) toplam 105 hasta alındı. PD hastaları beş alanda KDQOL-SF 1.3 alt ölçek puanları (duygusal rol, iş durumu, bilişsel işlev, diyaliz personelinin teşviki, hasta memnuniyeti) HD hastalarına göre daha yüksek puanlara sahipti. İleri yaş, kadın cinsiyet, düşük eğitim düzeyi, yüksek komorbidite skoru ve son 12 aydaki hastanede yatış sürelerinin yaşam kalitesi ile ilişkili olduğu bulundu. Bazı KDQOL-SF 1.3 alt ölçekleri ile hemoglobin, albümin arasında pozitif; ferritin düzeyleri arasında negatif korelasyonlar olduğu tespit edildi.
Sonuç: Çalışmamıza göre, SYK, PD hastalarında HD hastalarına göre, KDQOL-SF 1.3'ün spesifik alanlarında daha iyiydi. Yaş, cinsiyet, eğitim düzeyi, hemoglobin, albümin ve ferritin düzeyleri SYK ile ilişkiliydi.

References

  • 1. Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis. Journal of American Society of Nephrology.2001;12:2797–2806.
  • 2. Grzegorzewska AE, Izdebska A, Niepolski L, Warchoł W, Jagodziński PP. Self-Reported Physical Activity, Quality of Life, and Psychological Status in Relation to Plasma 25-Hydroxyvitamin D Concentration in Patients Treated with Hemodialysis. Kidney Blood Press Res. 2016;41(6):886-900.
  • 3. Al Wakeel J, Al Harbi A, Bayoumi M, Al-Suwaida K, Al Ghonaim M, Mishkiry A.Quality of life in hemodialysis and peritoneal dialysis patients in Saudi Arabia. Ann Saudi Med. 2012;32(6):570-4.
  • 4. Bohlke M, Nunes DL, Marini SS, Kitamura C, Andrade M, Von-Gysel MP. Predictors of quality of life among patients on dialysis in Southern Brazil. Sao Paulo Med J. 2008;126(5):252-6..
  • 5. Zazzeroni L, Pasquinelli G, Nanni E, Cremonini V, Rubbi I .Comparison of Quality of Life in Patients Undergoing Hemodialysis and Peritoneal Dialysis: a Systematic Review and Meta-Analysis. Kidney Blood Press Res. 2017;42(4):717-727.
  • 6. Cleary J, Drennan J. Quality of life of patients on haemodialysis for end-stage renal disease. J Adv Nurs. 2005;51(6):577-86.
  • 7. National Kidney Foundation. KDOQI clinical practice guideline and clinical practice recommendations: hemodialysis adequacy, peritoneal dialysis adequacy, and vascular access: update 2006. Am J Kidney Dis. 2006;48(suppl 1):1-322.
  • 8. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–383.
  • 9. Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index.J Clin Epidemiol. 1994;47(11):1245-51.
  • 10. Hays RD, Kallich JD, Mapes DL, Coons SJ, Amin N, Carter WB. Kidney Disease Quality of Life Short Form (KDQOL- SF), Version 1.3:A manual for use and scoring. 1997. Available from: http://www.rand.org/pubs/papers/2006/P7994.pdf
  • 11. Yildirim A, Ogutmen B, Bektas G, Isci E, Mete M, Tolgay HI. Translation, cultural adaptation, initial reliability, and validation of the Kidney Disease and Quality of Life-Short Form (KDQOL-SF 1.3) in Turkey. Transplantation Proceedings. 2007; 39: 51-54.
  • 12. Alvares J, Cesar CC, Acurcio Fde A, Andrade EI, Cherchiglia ML. Quality of life of patients in renal replacement therapy in Brazil: comparison of treatment modalities. Qual Life Res. 2012;21(6):983-91.
  • 13. Mittal SK, Ahern L, Flaster E, Mittal VS, Maesaka JK, Fishbane S. Self-assessed quality of life in peritoneal dialysis patients. Am J Nephrol. 2001;21(3):215-20.
  • 14. Fructuoso M, Castro R, Oliveira L, Prata C, Morgado T. Quality of life in chronic kidney disease. Nefrologia. 2011;31(1):91-6.
  • 15. Okpechi IG, Nthite T, Swanepoel CR. Health-related quality of life in patients on hemodialysis and peritoneal dialysis. Saudi J Kidney Dis Transpl. 2013;24(3):519-26.
  • 16. de Abreu MM, Walker DR, Sesso RC, Ferraz MB. Health-related quality of life of patients recieving hemodialysis and peritoneal dialysis in São Paulo, Brazil: a longitudinal study. Value Health. 2011;14(5 Suppl 1):119-21.
  • 17. Molsted S, Prescott L, Heaf J, Eidemak I. Assessment and clinical aspects of health-related quality of life in dialysis patients and patients with chronic kidney disease. Nephron Clin Pract. 2007;106(1):24-33.
  • 18. Lopes GB, Martins MT, Matos CM, Amorim JL, Leite EB, Miranda EA et al. Comparisons of quality of life measures between women and men on hemodialysis. Rev Assoc Med Bras. 2007;53(6):506-9.
  • 19. Valderrábano F, Jofre R, López-Gómez JM. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38(3):443-64.
  • 20. Kimmel PL, Peterson RA, Weihs KL, Simmens SJ, Boyle DH, Verme D et al. Behavioral compliance with dialysis prescription in hemodialysis patients. J Am Soc Nephrol. 1995:1826-34.
  • 21. Harris LE, Luft FC, Rudy DW, Tierney WM. Clinical correlation of functional status in patients with chronic renal insufficiency. Am J Kidney Dis. 1993;21:161-6.
  • 22. Moreno F, Lo´pez Go´mez JM, Sanz Guajardo D, Jofre R, Valderra´bano F. Quality of life in dialysis patients. A spanish multicentre study. Spanish Cooperative Renal Patients Quality of Life Study Group. Nephrol Dial Transplant. 1996;11(2):125-9.
  • 23. Mielck A, Reitmeir P, Vogelmann M, Leidl R. Impact of educational level on health-related quality of life (HRQL): results from Germany based on the EuroQol 5D (EQ-5D). Eur J Public Health. 2013;23(1):45-9.
  • 24. Stojanovic M, Stefanovic V. Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income. Artif Organs. 2007;31(1):53-60.
  • 25. Zhang AH, Cheng LT, Zhu N, Sun LH, Wang T. Comparison of quality of life and causes of hospitalization between hemodialysis and peritoneal dialysis patients in China. Health Qual Life Outcomes. 2007;5:49.
  • 26. Moreno F, Sanz-Guajardo D, López-Gómez JM, Jofre R, Valderrábano F. Increasing the hematocrit has a beneficial effect on quality of life and is safe in selected hemodialysis patients. Spanish Cooperative Renal Patients Quality of Life Study Group of the Spanish Society of Nephrology. J Am Soc Nephrol 2000;11:335-42.
  • 27. Blake PG, Flowerdew G, Blake RM, Oreopoulos DG. Serum albumin in patients on continuous ambulatory peritoneal dialysis--predictors and correlations with outcomes. J Am Soc Nephrol. 1993;3(8):1501-7.
  • 28. Spiegel DM, Anderson M, Campbell U, Hall K,Kelly G, McClure E, Breyer JA. Serum albumin: A marker for morbidity in peritoneal dialysis patients. Am J Kidney Dis. 1993;21:26.
  • 29. Unruh M, Benz R, Greene T, Yan G, Beddhu S, DeVita M et al. HEMO Study Group. Effects of hemodialysis dose and membrane flux on health-related quality of life in the HEMO Study. Kidney Int. 2004;66(1):355-66.
There are 29 citations in total.

Details

Primary Language English
Subjects Rheumatology and Arthritis
Journal Section Research
Authors

İpek Türk 0000-0001-5192-9045

Kenan Ateş This is me 0000-0002-1498-6267

Zeynep Bıyıklı This is me 0000-0003-0756-4960

Publication Date March 31, 2020
Acceptance Date January 1, 2020
Published in Issue Year 2020 Volume: 45 Issue: 1

Cite

MLA Türk, İpek et al. “Quality of Life and Associated Factors in Hemodialysis and Peritoneal Dialysis Patients”. Cukurova Medical Journal, vol. 45, no. 1, 2020, pp. 79-88, doi:10.17826/cumj.628274.