Abstract
Amaç: Bu çalışmanın amacı, skleroderma (SD) hastalarının mevcut ağız açıklığını ve periodontal bulgularını tespit etmek ve bu bulgular ile hastalığın alt grupları arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntem: Çalışmaya 74 yetişkin (60 kadın, 14 erkek) skleroderma hastası dahil edildi. Çalışma grupları skleroderma tipine (51 Diffüz, 23 lokalize) göre belirlendi. Çalışmaya katılan hastaların klinik periodontal parametreleri (Gingival indeks, plak indeksi ve cep derinliği) kaydedildi. Maksimum ağız açıklığı ve tükürük miktarı belirlendi. Temporamandibular eklem muayenesi yapıldı.
Bulgular: Skleroderma hastalarında ortalama ağız açıklığı 36,6±8,0 mm tespit edildi. Diffüz tip SD hastalarının ortalama ağız açıklığı (33,7±7,3 mm) ve lokalize tip SD hastalarının ağız açıklığı (43,0±5,4 mm) arasında istatistiksel olarak anlamlı bir fark bulundu. Diffüz tip SD hastalarında cep ortalama cep derinliğinin (3,17±0,9), lokalize tip SD hastalarına (2,69±0,6) göre istatistiksel anlamlı düzeyde yüksek olduğu tespit edildi.
Sonuç: Sklorederma yaygın olarak sınırlı ağız açıklığına ve periodontal dokulara etkisi nedeniyle çeşitli oral problemlere yol açabilir. SD hastalarının oral problemlerinin tedavisinde, ağız açma egzersizleri ve düzenli diş hekimi kontrolü önerilebilir. Ayrıca SD tipleri ile periodontal hastalıklar arasındaki ilişkinin etiyolojisi ve patogenezini değerlendiren ileriki çalışmalara ihtiyaç bulunmaktadır.
Keywords
References
- 1. Tyndall AJ, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, Bancel DF, Allanore Y, Müller-Ladner U, Distler O: Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann Rheum Dis. 2010;69:1809-15.
- 2. Derk CT, Jimenez SA: Systemic sclerosis: current views of its pathogenesis. Autoimmun Rev. 2003;2:181-91.
- 3. LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger Jr T, Rowell N, Wollheim F: Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol. 1988;15:202-05.
- 4. Masi AT, Diagnostic SFSCotARA, Committee TC: Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum. 1980;23:581-90.
- 5. Walker U, Tyndall A, Czirjak L, Denton C, Farge-Bancel D, Kowal-Bielecka O, Müller-Ladner U, Bocelli-Tyndall C, Matucci-Cerinic M: Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Ann Rheum Dis. 2007;66:754-63.
- 6. Chifflot H, Fautrel B, Sordet C, Chatelus E, Sibilia J. Incidence and prevalence of systemic sclerosis: a systematic literature review. Semin Arthritis Rheum. 2008;37:223-235.
- 7. Barnes J, Mayes MD: Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers. Curr Opin Rheumatol. 2012;24:165-70.
- 8. Almeida C, Almeida I, Vasconcelos C: Quality of life in systemic sclerosis. Autoimmun Rev. 2015;14:1087-96.
- 9. Veale B, Jablonski R, Frech T, Pauling J: Orofacial manifestations of systemic sclerosis. Br Dent J. 2016;221:305-10.
- 10. Vincent C, Agard C, Barbarot S, N'guyen J, Planchon B, Durant C, Pistorius M, Dreno B, Ponge T, Stalder J: Orofacial manifestations of systemic sclerosis: a study of 30 consecutive patients. Rev Stomatol Chir Maxillofac Chir Orale. 2010;111:128-34.
- 11. Jung S, Martin T, Schmittbuhl M, Huck O: The spectrum of orofacial manifestations in systemic sclerosis: a challenging management. Oral Dis. 2017;23:424-39.
- 12. Gutman D, Ben-Aryeh H: The influence of age on salivary content and rate of flow. J Oral Maxillofac Surg. 1974;3:314-17.
- 13. Poole J, Brewer C, Rossie K, Good C, Conte C, Steen V: Factors related to oral hygiene in persons with scleroderma. Int J Dent Hyg. 2005;3:13-17.
- 14. Löe H, Silness J: Periodontal disease in pregnancy I. Prevalence and severity. Acta Odontol Scand. 1963;21:533-51.
- 15. Silness J, Löe H: Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand. 1964;22:121-35.
- 16. Naylor WP: Oral management of the scleroderma patient. J Am Dent Assoc. 1982;105:814-17.
- 17. Weisman RA, Calcaterra TC: Head and neck manifestations of scleroderma. Ann Otol Rhinol Laryngol. 1978;87:332-39.
- 18. Eversole L, Jacobsen P, Stone C: Oral and gingival changes in systemic sclerosis (scleroderma). J Periodontol. 1984;55:175-78.
- 19. Jagadish R, Mehta DS, Jagadish P: Oral and periodontal manifestations associated with systemic sclerosis: A case series and review. J Indian Soc Periodontol. 2012;16:271.
- 20. White SC, Pharoah MJ. Oral radiology-E-Book: Principles and interpretation. Elsevier Health Sciences, 2014.
- 21. Stafne EC: Dental roentgenologic manifestations of systemic disease. III. Granulomatous disease, Paget's disease, acrosclerosis and others. Radiology. 1952;58:820-9.
- 22. Marmary Y, Glaiss R, Pisanty S: Scleroderma: oral manifestations. Oral Surg Oral Med Oral Pathol. 1981;52:32-7.
- 23. Jagadish R, Mehta DS, Jagadish P: Oral and periodontal manifestations associated with systemic sclerosis: A case series and review. J Indian Soc Periodontol. 2012;16:271-4.
- 24. Alarcón-Segovia D, Ibánez G, Hernández-Ortíz J, Velázquez-Forero F, González-Jiménez Y: Sjögren's syndrome in progressive systemic sclerosis (scleroderma). Am J Med. 1974;57:78-85.
- 25. Hebbar M, Janin A, Huglo D, Copin MC, Lafyatis R, Devulder B, Marchandise X, Gosset D: Xerostomia in systemic sclerosis: systematic evaluation by salivary scintigraphy and lip biopsy in thirty-four patients. Arthritis Rheum.1994;37:439-41.
Abstract
Purpose: The aim of this study is to determine the maximum mouth opening and periodontal findings of scleroderma (SD) patients and to evaluate the relationship of these findings with the subgroups of the disease.
Materials and Methods: Seventy-four adults (60 females, 14 males) with scleroderma were included in this study. Study groups were determined according to the type of scleroderma (51 Diffuse, 23 localized). Clinical periodontal parameters (gingival index, plaque index and periodontal pocket depth) of the patients were recorded. Maximum mouth opening and saliva amount were determined. Temporomandibular joint examination was performed.
Results: The mean mouth opening in patients with SD was 36.6 ± 8.0 mm. A statistically significant difference was found between the mean mouth opening of the diffuse type SD patients (33.7 ± 7.3 mm) compared to the localized type SD patients (43.0 ± 5.4 mm). In diffuse type SD patients, the mean pocket depth (3.17 ± 0.9) was statistically significantly higher than in localized type SD patients (2.69 ± 0.6).
Conclusion: Scleroderma may cause various oral problems due to its wide range of limited mouth opening and its effect on periodontal tissues. Mouth opening exercises and regular dentist check-ups may be recommended in the treatment of oral problems in SD patients. Further studies are needed to evaluate the relationship between SD types and periodontal diseases in terms of etiology and pathogenesis.
Keywords
References
- 1. Tyndall AJ, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, Bancel DF, Allanore Y, Müller-Ladner U, Distler O: Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann Rheum Dis. 2010;69:1809-15.
- 2. Derk CT, Jimenez SA: Systemic sclerosis: current views of its pathogenesis. Autoimmun Rev. 2003;2:181-91.
- 3. LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger Jr T, Rowell N, Wollheim F: Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol. 1988;15:202-05.
- 4. Masi AT, Diagnostic SFSCotARA, Committee TC: Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum. 1980;23:581-90.
- 5. Walker U, Tyndall A, Czirjak L, Denton C, Farge-Bancel D, Kowal-Bielecka O, Müller-Ladner U, Bocelli-Tyndall C, Matucci-Cerinic M: Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Ann Rheum Dis. 2007;66:754-63.
- 6. Chifflot H, Fautrel B, Sordet C, Chatelus E, Sibilia J. Incidence and prevalence of systemic sclerosis: a systematic literature review. Semin Arthritis Rheum. 2008;37:223-235.
- 7. Barnes J, Mayes MD: Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers. Curr Opin Rheumatol. 2012;24:165-70.
- 8. Almeida C, Almeida I, Vasconcelos C: Quality of life in systemic sclerosis. Autoimmun Rev. 2015;14:1087-96.
- 9. Veale B, Jablonski R, Frech T, Pauling J: Orofacial manifestations of systemic sclerosis. Br Dent J. 2016;221:305-10.
- 10. Vincent C, Agard C, Barbarot S, N'guyen J, Planchon B, Durant C, Pistorius M, Dreno B, Ponge T, Stalder J: Orofacial manifestations of systemic sclerosis: a study of 30 consecutive patients. Rev Stomatol Chir Maxillofac Chir Orale. 2010;111:128-34.
- 11. Jung S, Martin T, Schmittbuhl M, Huck O: The spectrum of orofacial manifestations in systemic sclerosis: a challenging management. Oral Dis. 2017;23:424-39.
- 12. Gutman D, Ben-Aryeh H: The influence of age on salivary content and rate of flow. J Oral Maxillofac Surg. 1974;3:314-17.
- 13. Poole J, Brewer C, Rossie K, Good C, Conte C, Steen V: Factors related to oral hygiene in persons with scleroderma. Int J Dent Hyg. 2005;3:13-17.
- 14. Löe H, Silness J: Periodontal disease in pregnancy I. Prevalence and severity. Acta Odontol Scand. 1963;21:533-51.
- 15. Silness J, Löe H: Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand. 1964;22:121-35.
- 16. Naylor WP: Oral management of the scleroderma patient. J Am Dent Assoc. 1982;105:814-17.
- 17. Weisman RA, Calcaterra TC: Head and neck manifestations of scleroderma. Ann Otol Rhinol Laryngol. 1978;87:332-39.
- 18. Eversole L, Jacobsen P, Stone C: Oral and gingival changes in systemic sclerosis (scleroderma). J Periodontol. 1984;55:175-78.
- 19. Jagadish R, Mehta DS, Jagadish P: Oral and periodontal manifestations associated with systemic sclerosis: A case series and review. J Indian Soc Periodontol. 2012;16:271.
- 20. White SC, Pharoah MJ. Oral radiology-E-Book: Principles and interpretation. Elsevier Health Sciences, 2014.
- 21. Stafne EC: Dental roentgenologic manifestations of systemic disease. III. Granulomatous disease, Paget's disease, acrosclerosis and others. Radiology. 1952;58:820-9.
- 22. Marmary Y, Glaiss R, Pisanty S: Scleroderma: oral manifestations. Oral Surg Oral Med Oral Pathol. 1981;52:32-7.
- 23. Jagadish R, Mehta DS, Jagadish P: Oral and periodontal manifestations associated with systemic sclerosis: A case series and review. J Indian Soc Periodontol. 2012;16:271-4.
- 24. Alarcón-Segovia D, Ibánez G, Hernández-Ortíz J, Velázquez-Forero F, González-Jiménez Y: Sjögren's syndrome in progressive systemic sclerosis (scleroderma). Am J Med. 1974;57:78-85.
- 25. Hebbar M, Janin A, Huglo D, Copin MC, Lafyatis R, Devulder B, Marchandise X, Gosset D: Xerostomia in systemic sclerosis: systematic evaluation by salivary scintigraphy and lip biopsy in thirty-four patients. Arthritis Rheum.1994;37:439-41.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Clinical Sciences, Rheumatology and Arthritis |
| Journal Section | Research |
| Authors | |
| Publication Date | March 31, 2021 |
| Acceptance Date | September 10, 2020 |
| Published in Issue | Year 2021 Volume: 46 Issue: 1 |
