Research Article
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Year 2023, Volume: 9 Issue: 5 - September 2023, 1105 - 1113, 04.09.2023
https://doi.org/10.18621/eurj.1341860

Abstract

References

  • 1. Peden M, Oyegbite K, Ozanne-Smith J, Hyder AA, Branche C, Rahman AKMF, et al. World Report on Child Injury Prevention. Geneva: World Health Organization; 2008.
  • 2. Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Bronstein AC, Rivers LJ, et al. 2020 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 38th Annual Report. Clin Toxicol (Phila) 2021;59:1282-501.
  • 3. Hepp U, Stulz N, Unger-Köppel J, Ajdacic-Gross V. Methods of suicide used by children and adolescents. Eur Child Adolesc Psychiatry 2012;21:67-73.
  • 4. Mintegi S, Azkunaga B, Prego J, Qureshi N, Dalziel SR, Arana-Arri E, et al. Pediatric Emergency Research Networks (PERN) Poisoning Working Group. International epidemiological differences in acute poisonings in pediatric emergency departments. Pediatr Emerg Care 2019;35:50-7.
  • 5. Even KM, Armsby CC, Bateman ST. Poisonings requiring admission to the pediatric intensive care unit: A 5-year review. Clin Toxicol (Phila). 2014 Jun;52(5):519-24.
  • 6. Li Z, Xiao L, Yang L, Li S, Tan L. Characterization of acute poisoning in hospitalized children in Southwest China. Front Pediatr 2021;9:727900.
  • 7. Suh J-H, Eo E-K. The differences of clinical aspects in children and adolescents poisoning. J Korean Soc Clin Toxicol 2006;4:17-24.
  • 8. Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Brooks DE, Dibert KW, et al. 2019 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th Annual Report. Clin Toxicol (Phila) 2020;58:1360-541.
  • 9. Pianca TG, Sordi AO, Hartmann TC, von Diemen L. Identification and initial management of intoxication by alcohol and other drugs in the pediatric emergency room. J Pediatr (Rio J). 2017;93(Suppl 1)46-52.
  • 10. Howells K, Caple A, Jones M. Are boys more physically active than girls during a primary school day? Prim Phys Educ Matters 2010;5(3):xvii-xix.
  • 11. Marano M, Rossi F, Ravà L, Khalil Ramla M, Pisani M, Bottari G, et al. Acute toxic exposures in children: analysis of a three year registry managed by a Pediatric poison control Center in Italy. Ital J Pediatr 2021;47:125.
  • 12. Peden M. World report on child injury prevention appeals to "Keep Kids Safe". Inj Prev 2008;14:413-4.
  • 13. Kizilyildiz BS, Karaman K, Özen S, Üner A. Acute intoxications among Turkish children. Minerva Pediatr 2018;70:46-50.
  • 14. Ozdemir R, Bayrakci B, Tekşam O, Yalçin B, Kale G. Thirty-three-year experience on childhood poisoning. Turk J Pediatr 2012;54:251-9.
  • 15. World Health Organization. Preventing suicide: A global imperative. World Health Organization, 2014.
  • 16. Hammad TA, Laughren T, Racoosin J. Suicidality in pediatric patients treated with antidepressant drugs. Arch Gen Psychiatry 2006;63:332-9.
  • 17. Nock MK, Green JG, Hwang I, McLaughlin KA, Sampson NA, Zaslavsky AM, et al. Prevalence, correlates, and treatment of lifetime suicidal behavior among adolescents: results from the National Comorbidity Survey Replication Adolescent Supplement. JAMA Psychiatry 2013;70:300-10.
  • 18. Himwaze C, Mucheleng’anga L. A case series of child suicides in Lusaka, Zambia. Forensic Sci Int Rep 2021;3:100191.
  • 19. FDA U. Public Health Advisory. Suicidality in children and adolescents being treated with antidepressant Medications. October 15, 2004.
  • 20. Sheftall AH, Asti L, Horowitz LM, Felts A, Fontanella CA, Campo JV, et al. Suicide in elementary school-aged children and early adolescents. Pediatrics 2016;138:e20160436.
  • 21. US Food and Drug Administration. "FDA proposes new warnings about suicidal thinking, behavior in young adults who take antidepressant medications. US Department of Health and Human Services." http://www. fda. gov/NewsEvents/Newsroom/PressAnnouncements/2007/ucm108905. Htm (2007).
  • 22. Hawton K, Rodham K, Evans E, Weatherall R. Deliberate self harm in adolescents: self report survey in schools in England. BMJ 2002;325:1207-11.
  • 23. Finkelstein Y, Macdonald EM, Hollands S, Hutson JR, Sivilotti ML, Canadian Drug Safety and Effectiveness Research Network (CDSERN). Long-term outcomes following self-poisoning in adolescents: a population-based cohort study. Lancet Psychiatry 2015;2:532-9.
  • 24. Amin R, Helgesson M, Runeson B, Tinghög P, Mehlum L, Qin P, et al. Suicide attempt and suicide in refugees in Sweden - a nationwide population-based cohort study. Psychol Med 2021;51:254-63.

Acute poisonings requiring intensive care in childhood and a hidden threat, suicide attempts: a single-center experience

Year 2023, Volume: 9 Issue: 5 - September 2023, 1105 - 1113, 04.09.2023
https://doi.org/10.18621/eurj.1341860

Abstract

Objectives: Very few studies have been conducted to identify the conditions that cause poisoning in pediatric patients needing intensive care, both by age group and toxic agent factor. This study will support the development of strategies for poisoning prevention measures by comparing the data in our region with other data in the world.

Methods: This study is a single-centered, retrospective study. The baseline status of acute poisoning was defined in pediatric patients aged one month to 18 years who required intensive care hospitalization between November 2017 and March 2022.

Results: There were 148 patient admissions due to acute poisonings (5.2% of all admissions, 69.6% females, median age: 13.6 months). Our study revealed that acute poisoning in children is caused mainly by pharmacological (88.5%), oral intake (97.3%) and at home (85.8%). It was observed that intoxication peaked at two different ages; the first peak was at preschool (33.1%), and the second peak was at adolescence (58.7%). In the univariate analysis, females (odds ratio [OR]=4.1), adolescents (OR=167.6), psychiatric drug users (OR=55.5), and multiple drug intoxications (OR=3.6) were associated with more suicides. Being adolescents and using psychiatric medication contributed significantly to suicide attempts in multivariate analysis (OR=145.3 and OR=37.9). None of our patients died.

Conclusions: Preventing both poisoning and suicide attempts is the most critical priority. However, we suggest prevention strategies should be strengthened even if mortality is not observed. Furthermore, our study shows that suicide attempts are very likely to be repeated, especially if an underlying psychiatric illness exists.

References

  • 1. Peden M, Oyegbite K, Ozanne-Smith J, Hyder AA, Branche C, Rahman AKMF, et al. World Report on Child Injury Prevention. Geneva: World Health Organization; 2008.
  • 2. Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Bronstein AC, Rivers LJ, et al. 2020 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 38th Annual Report. Clin Toxicol (Phila) 2021;59:1282-501.
  • 3. Hepp U, Stulz N, Unger-Köppel J, Ajdacic-Gross V. Methods of suicide used by children and adolescents. Eur Child Adolesc Psychiatry 2012;21:67-73.
  • 4. Mintegi S, Azkunaga B, Prego J, Qureshi N, Dalziel SR, Arana-Arri E, et al. Pediatric Emergency Research Networks (PERN) Poisoning Working Group. International epidemiological differences in acute poisonings in pediatric emergency departments. Pediatr Emerg Care 2019;35:50-7.
  • 5. Even KM, Armsby CC, Bateman ST. Poisonings requiring admission to the pediatric intensive care unit: A 5-year review. Clin Toxicol (Phila). 2014 Jun;52(5):519-24.
  • 6. Li Z, Xiao L, Yang L, Li S, Tan L. Characterization of acute poisoning in hospitalized children in Southwest China. Front Pediatr 2021;9:727900.
  • 7. Suh J-H, Eo E-K. The differences of clinical aspects in children and adolescents poisoning. J Korean Soc Clin Toxicol 2006;4:17-24.
  • 8. Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Brooks DE, Dibert KW, et al. 2019 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th Annual Report. Clin Toxicol (Phila) 2020;58:1360-541.
  • 9. Pianca TG, Sordi AO, Hartmann TC, von Diemen L. Identification and initial management of intoxication by alcohol and other drugs in the pediatric emergency room. J Pediatr (Rio J). 2017;93(Suppl 1)46-52.
  • 10. Howells K, Caple A, Jones M. Are boys more physically active than girls during a primary school day? Prim Phys Educ Matters 2010;5(3):xvii-xix.
  • 11. Marano M, Rossi F, Ravà L, Khalil Ramla M, Pisani M, Bottari G, et al. Acute toxic exposures in children: analysis of a three year registry managed by a Pediatric poison control Center in Italy. Ital J Pediatr 2021;47:125.
  • 12. Peden M. World report on child injury prevention appeals to "Keep Kids Safe". Inj Prev 2008;14:413-4.
  • 13. Kizilyildiz BS, Karaman K, Özen S, Üner A. Acute intoxications among Turkish children. Minerva Pediatr 2018;70:46-50.
  • 14. Ozdemir R, Bayrakci B, Tekşam O, Yalçin B, Kale G. Thirty-three-year experience on childhood poisoning. Turk J Pediatr 2012;54:251-9.
  • 15. World Health Organization. Preventing suicide: A global imperative. World Health Organization, 2014.
  • 16. Hammad TA, Laughren T, Racoosin J. Suicidality in pediatric patients treated with antidepressant drugs. Arch Gen Psychiatry 2006;63:332-9.
  • 17. Nock MK, Green JG, Hwang I, McLaughlin KA, Sampson NA, Zaslavsky AM, et al. Prevalence, correlates, and treatment of lifetime suicidal behavior among adolescents: results from the National Comorbidity Survey Replication Adolescent Supplement. JAMA Psychiatry 2013;70:300-10.
  • 18. Himwaze C, Mucheleng’anga L. A case series of child suicides in Lusaka, Zambia. Forensic Sci Int Rep 2021;3:100191.
  • 19. FDA U. Public Health Advisory. Suicidality in children and adolescents being treated with antidepressant Medications. October 15, 2004.
  • 20. Sheftall AH, Asti L, Horowitz LM, Felts A, Fontanella CA, Campo JV, et al. Suicide in elementary school-aged children and early adolescents. Pediatrics 2016;138:e20160436.
  • 21. US Food and Drug Administration. "FDA proposes new warnings about suicidal thinking, behavior in young adults who take antidepressant medications. US Department of Health and Human Services." http://www. fda. gov/NewsEvents/Newsroom/PressAnnouncements/2007/ucm108905. Htm (2007).
  • 22. Hawton K, Rodham K, Evans E, Weatherall R. Deliberate self harm in adolescents: self report survey in schools in England. BMJ 2002;325:1207-11.
  • 23. Finkelstein Y, Macdonald EM, Hollands S, Hutson JR, Sivilotti ML, Canadian Drug Safety and Effectiveness Research Network (CDSERN). Long-term outcomes following self-poisoning in adolescents: a population-based cohort study. Lancet Psychiatry 2015;2:532-9.
  • 24. Amin R, Helgesson M, Runeson B, Tinghög P, Mehlum L, Qin P, et al. Suicide attempt and suicide in refugees in Sweden - a nationwide population-based cohort study. Psychol Med 2021;51:254-63.
There are 24 citations in total.

Details

Primary Language English
Subjects Pediatric Emergency, Pediatric Intensive Care , Forensic Medicine
Journal Section Original Articles
Authors

Arzu Oto 0000-0003-0229-2759

Serbülent Kılıç 0000-0001-5224-4582

Musa Sahın 0000-0002-0736-2229

Early Pub Date August 22, 2023
Publication Date September 4, 2023
Submission Date August 12, 2023
Acceptance Date August 19, 2023
Published in Issue Year 2023 Volume: 9 Issue: 5 - September 2023

Cite

AMA Oto A, Kılıç S, Sahın M. Acute poisonings requiring intensive care in childhood and a hidden threat, suicide attempts: a single-center experience. Eur Res J. September 2023;9(5):1105-1113. doi:10.18621/eurj.1341860

e-ISSN: 2149-3189 


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