Abstract
Enterococcus
casseliflavus çeşitli
enfeksiyonlarda rol oynayan nadir görülen bir patojendir. İnsanlarda sepsis gibi
enfeksionlara yol açar ve bunlar genellikle erişkinlerde görülen vankomisin
tedavisine direnç gösterebilen vakalardır. Biz bu raporda, 17 aylık bir kız
çocuğunda linezolid ile başarılı bir şekilde tedavi edilen ve nadir görülen
vankomisin dirençli bir E. casseliflavus menenjiti olgusunu
sunmaktayız. Hasta ondört günlük linezolid tedavisi ile düzeldi. Vankomisin
dirençli E. casseliflavus çocuklarda görülen menejitlerin
potansiyel patojen bir nedeni olabilir ve tedavide linezolid kullanımı ile iyi
klinik sonuçlar alınmaktadır. Çocuk hastalarda vankomisin tedavisine cevap
alınamayan durumlarda, vankomisin dirençli E.
casseliflavus düşünülmelidir.
Keywords
References
- 1. Cetinkaya Y, Falk P, Mayhall CG. Vancomycin-Resistant Enterococci. Clin Microbiol Rev. 2000; 13(4): 686–07.
- 2. Reid KC, Cockerill III FR, Patel R: Clinical and epidemiological features of Enterococcus casseliflavus/flavescens and Enterococcus gallinarum bacteremia: a report of 20 cases. Clin Infect Dis 2001; 32(11):1540-46
- 3. Verma R, Barovo, Al. Enterococcus casseliflavus septicaemia associated with hepatobiliary infection in a 75-year-old man. BMJ Case Rep. 2017 12;2017. pii: bcr-2017-219636. doi: 10.1136/bcr-2017-219636.
- 4. Shaked H, Carmeli Y, Schwartz D, Siegman-Igra Y. Enterococcal bacteraemia: epidemiological, microbiological, clinical and prognostic characteristics, and the impact of high level gentamicin resistance. Scand J Infect Dis 2006, 38:995-00.
- 5. Pintado V, Cabellos C, Moreno S, Meseguer MA, Ayats J, Viladrich PF.Enterococcal meningitis: a clinical study of 39 cases and review of the literature. Medicine (Baltimore) 2003; 82: 346-64.
- 6. Britt NS, potter EM. Clinical epidemiology of vancomycin- resistant Enterococcus gallinarum and Enterococcus casseliflavus bloodstream infections. J Glob Antimicrob Resist. 2016; 5: 57-61.
- 7. Choi SH, Lee SO, Kim TH, Chung JW, Choo EJ, Kwak YG, Kim MN, Kim YS, Woo JH, Ryu J, Kim NJ. Clinical features and outcomes of bacteremia caused by Enterococcus casseliflavus and Enterococcus gallinarum: analysis of 56 cases. Clin Infect Dis 2004; 38(1):53-1
- 8. Britt NS, Potter EM, Patel N, Steed ME. Comparison of the effectiveness and safety of linezolid and daptomycin in vancomycin-resistant Eneterococcal bloodstream infection; a national cohort study of veterns affairs patients. Clin Infect Dis 2015; 61:871-8206-8.
- 9. Iaria C, Stassi G, Costa GB, Di Leo R, Toscano A, Cascio A. Enterococcal meningitis caused by Enterococcus casseliflavus. First case report. BMC Infect Dis 2005; 5(1):3.
- 10. Li MC, Guo HC, Chen G, Kong F, Zhang QH. Meningitis caused by Enterococcus casseliflavus with refractory cerebrospinal fluid leakage following endoscopic endonasal removal of skull base chondrosarcoma. Chin Med J (Engl) 2011;124(20):3440.
- 11. Zırakzadeh A, Patel R. Vancomycin-Resistant Enterococci: Colonization, infection, detection, and treatment. Mayo Clin Proc 2006; 81: 529-36.
- 12. Toye B, Shymanski J, Bobrowska M, Woods W, Ramotar K. Clinical and epidemiological significance of enterococci intrinsically resistant to vancomycin (possessing the vanC genotype. J Clin Microbiol 1997;35(12):3166-70.
- 13. Murray BE. Vancomycin-resistant enterococci. Am J Med 1997;102(3):284–93.
- 14. Mizell KN, Carter JE: Vancomycin-resistant Enterococcus faecium meningitis successfully treated with linezolid. South Med J 2008; 101:569-70.
A Case of Bacterial Meningitis Due to Vancomycin Resistant Enterococcus Casseliflavus in a Nursling Child
Abstract
Enterococcus casseliflavus is a rare pathogen that
plays a role in various infections. It causes infections such as sepsis in
humans. In adults, these are usually vancomycin resistant cases. We present a
rare case of vancomycin-resistant E. casseliflavus meningitis in a
17-months-old girl who has been successfully treated with linezolid. The
patient completely recovered after fourteen days of linezolid treatment.
Vancomycin-resistant E. casseliflavus may be a potential pathogenic
cause of meningitis in children with good clinical outcome by linezolid
treatment. Linezolid therapy should be considered in children cases when
vancomycin therapy failed.
References
- 1. Cetinkaya Y, Falk P, Mayhall CG. Vancomycin-Resistant Enterococci. Clin Microbiol Rev. 2000; 13(4): 686–07.
- 2. Reid KC, Cockerill III FR, Patel R: Clinical and epidemiological features of Enterococcus casseliflavus/flavescens and Enterococcus gallinarum bacteremia: a report of 20 cases. Clin Infect Dis 2001; 32(11):1540-46
- 3. Verma R, Barovo, Al. Enterococcus casseliflavus septicaemia associated with hepatobiliary infection in a 75-year-old man. BMJ Case Rep. 2017 12;2017. pii: bcr-2017-219636. doi: 10.1136/bcr-2017-219636.
- 4. Shaked H, Carmeli Y, Schwartz D, Siegman-Igra Y. Enterococcal bacteraemia: epidemiological, microbiological, clinical and prognostic characteristics, and the impact of high level gentamicin resistance. Scand J Infect Dis 2006, 38:995-00.
- 5. Pintado V, Cabellos C, Moreno S, Meseguer MA, Ayats J, Viladrich PF.Enterococcal meningitis: a clinical study of 39 cases and review of the literature. Medicine (Baltimore) 2003; 82: 346-64.
- 6. Britt NS, potter EM. Clinical epidemiology of vancomycin- resistant Enterococcus gallinarum and Enterococcus casseliflavus bloodstream infections. J Glob Antimicrob Resist. 2016; 5: 57-61.
- 7. Choi SH, Lee SO, Kim TH, Chung JW, Choo EJ, Kwak YG, Kim MN, Kim YS, Woo JH, Ryu J, Kim NJ. Clinical features and outcomes of bacteremia caused by Enterococcus casseliflavus and Enterococcus gallinarum: analysis of 56 cases. Clin Infect Dis 2004; 38(1):53-1
- 8. Britt NS, Potter EM, Patel N, Steed ME. Comparison of the effectiveness and safety of linezolid and daptomycin in vancomycin-resistant Eneterococcal bloodstream infection; a national cohort study of veterns affairs patients. Clin Infect Dis 2015; 61:871-8206-8.
- 9. Iaria C, Stassi G, Costa GB, Di Leo R, Toscano A, Cascio A. Enterococcal meningitis caused by Enterococcus casseliflavus. First case report. BMC Infect Dis 2005; 5(1):3.
- 10. Li MC, Guo HC, Chen G, Kong F, Zhang QH. Meningitis caused by Enterococcus casseliflavus with refractory cerebrospinal fluid leakage following endoscopic endonasal removal of skull base chondrosarcoma. Chin Med J (Engl) 2011;124(20):3440.
- 11. Zırakzadeh A, Patel R. Vancomycin-Resistant Enterococci: Colonization, infection, detection, and treatment. Mayo Clin Proc 2006; 81: 529-36.
- 12. Toye B, Shymanski J, Bobrowska M, Woods W, Ramotar K. Clinical and epidemiological significance of enterococci intrinsically resistant to vancomycin (possessing the vanC genotype. J Clin Microbiol 1997;35(12):3166-70.
- 13. Murray BE. Vancomycin-resistant enterococci. Am J Med 1997;102(3):284–93.
- 14. Mizell KN, Carter JE: Vancomycin-resistant Enterococcus faecium meningitis successfully treated with linezolid. South Med J 2008; 101:569-70.
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 22, 2018 |
| Submission Date | March 26, 2018 |
| Acceptance Date | April 13, 2018 |
| Published in Issue | Year 2018 Volume: 15 Issue: 1 |
Harran Üniversitesi Tıp Fakültesi Dergisi / Journal of Harran University Medical Faculty