Research Article
Year 2022,
Volume: 10 Issue: 3, 809 - 815, 14.11.2022
Abstract
In this study, it was aimed to evaluate asthma patients who applied to the chest diseases outpatient clinic in terms of allergies. 240 asthma patients over the age of 18 who applied to the chest diseases outpatient clinic with the diagnosis of asthma were evaluated retrospectively. No statistical difference was obtained between the education status, employment status, presence of additional disease, presence of chronic disease, skin prick test and Total IgE results in terms of asthma severity and AKT. While no correlation was obtained between AKT and eosinophil percentage; asthma severity was associated with the eosinophil percentage (p=0.039). According to the results of the skin prick test, the most common allergens were detected to be house dust, pollen and animal feather. Early detection of allergy in asthma patients is very important for the follow-up and treatment of patients. While the eosinophil percentage provides benefits in determining future risks in asthma, the Total IgE result is a test that guides to anti-IgE (Omalizumab) therapy. In the patients with severe asthma which is resistant to treatment, peripheral blood eosinophils and Total IgE should be checked, and appropriate patients should be referred to advanced centers.
Keywords
References
- Anto, J. M., Bousquet, J., Akdis, M., Auffray, C., Keil, T., Momas, I., …Xu, C.J. (2017). Mechanisms of the Development of Allergy (MeDALL): Introducing novelconcepts in allergy phenotypes. J Allergy Clin Immunol, 139(2), 388-399.
- Barnthouse, M. ve Jones, B.L. (2019). The Impact of Environmental Chronic and Toxic Stress on Asthma. Clin Rev Allergy Immunol, 57(3), 427-438.
- Becker, A. B. ve Abrams, E. M. (2017). Asthma guidelines: The global initiative for asthma in relation to national guidelines. Curr Opin Allergy Clin Immunol, 17, 99-103.
- British Guideline on the Management of Asthma (2018). A national clinical guideline. BTS, SIGN, Edinburgh.
- Corrado, A., Renda, T., Polese, G. ve Rossi, A. (2013). Assessment of asthma control: The SERENA study. Respiratory Med, 107, 1659-1666.
- den Dekker, H. T., Sonnenschein-van der Voort A. M. M., de Jongste, J. C., Anessi-Maesano, I., Arshad, S. H., Barros, H., …Duijts, L. (2016). Early growth characcteristics and the risk of reduced lungfunction and asthma: A meta-analysis of 25000 children. J Allergy Clin Immunol, 137, 1026-1035.
- Gaffin, J. M. ve Phipatanakul, W. (2009). The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol, 9, 128–135.
- Global strategy for asthma management and prevention (2020). Global Initiative for Asthma (GINA), 2020.
- Lazic, N., Roberts, G., Custovic, A., Belgrave, D., Bishop, C. M., Winn, J., …Simpson, A. (2013). Multiple atopy phenotypes and their associations with asthma: similar findings from two birth cohorts. Allergy, 68, 764-70.
- The National Asthma Council Australia (2019). Asthma Management Handbook.
- Toppila-Salmi, S., Huhtala, H., Karjalainen, J., Renkonen, R., Mäkelä, M. J., Wang, D. Y. ve Pekkanen, J. (2015). Sensitization pattern affects the asthma risk in Finnish adult population. Allergy, 70(9), 1112-1120.
- Türk Toraks Derneği (2016). Ulusal astım tanı ve tedavi rehberi. Toraks Dergisi, 4-31.
Year 2022,
Volume: 10 Issue: 3, 809 - 815, 14.11.2022
Abstract
Bu çalışmada göğüs hastalıkları polikliniğine başvuran astım hastalarının alerji açısından değerlendirmesi amaçlandı. Astım tanısı ile göğüs hastalıkları polikliniğine başvuran 18 yaş üzeri 240 astım hastası retrospektif olarak değerlendirildi. Hastaların yaş, cinsiyet, eğitim durumu, çalışma durumu, ek hastalık, kronik hastalık, Total IgE sonucu, eozinofil yüzdesi, deri prik testi, astım şiddeti ve astım kontrol testi (AKT) sonuçları kaydedildi. Astım şiddeti ve AKT ile hastaların eğitim durumu, çalışma durumu, ek hastalık varlığı, kronik hastalık varlığı, deri prik testi ve Total IgE sonucu arasında istatistiksel fark saptanmadı. AKT ile eozinofil yüzdesi arasında ilişki saptanmazken; astım şiddeti ile eozinofil yüzdesi ilişkiliydi (p=0.039). Deri prik testi sonucuna göre alerjen olarak en sık ev tozu, polen ve hayvan tüyü saptandı. Astım hastalarında alerjinin erken dönemde saptanması hastaların takip ve tedavisi açısından çok önemlidir. Eozinofil yüzdesi astımda gelecek riskleri belirleme yönünden yarar sağlarken, Total IgE sonucu ise anti IgE (Omalizumab) tedavisi konusunda yol gösteren bir tetkiktir. Tedaviye dirençli ağır astım hastalarında periferik kanda eozinofil ve Total IgE mutlaka bakılmalı, uygun hastalar ileri merkezlere yönlendirilmelidir.
Keywords
References
- Anto, J. M., Bousquet, J., Akdis, M., Auffray, C., Keil, T., Momas, I., …Xu, C.J. (2017). Mechanisms of the Development of Allergy (MeDALL): Introducing novelconcepts in allergy phenotypes. J Allergy Clin Immunol, 139(2), 388-399.
- Barnthouse, M. ve Jones, B.L. (2019). The Impact of Environmental Chronic and Toxic Stress on Asthma. Clin Rev Allergy Immunol, 57(3), 427-438.
- Becker, A. B. ve Abrams, E. M. (2017). Asthma guidelines: The global initiative for asthma in relation to national guidelines. Curr Opin Allergy Clin Immunol, 17, 99-103.
- British Guideline on the Management of Asthma (2018). A national clinical guideline. BTS, SIGN, Edinburgh.
- Corrado, A., Renda, T., Polese, G. ve Rossi, A. (2013). Assessment of asthma control: The SERENA study. Respiratory Med, 107, 1659-1666.
- den Dekker, H. T., Sonnenschein-van der Voort A. M. M., de Jongste, J. C., Anessi-Maesano, I., Arshad, S. H., Barros, H., …Duijts, L. (2016). Early growth characcteristics and the risk of reduced lungfunction and asthma: A meta-analysis of 25000 children. J Allergy Clin Immunol, 137, 1026-1035.
- Gaffin, J. M. ve Phipatanakul, W. (2009). The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol, 9, 128–135.
- Global strategy for asthma management and prevention (2020). Global Initiative for Asthma (GINA), 2020.
- Lazic, N., Roberts, G., Custovic, A., Belgrave, D., Bishop, C. M., Winn, J., …Simpson, A. (2013). Multiple atopy phenotypes and their associations with asthma: similar findings from two birth cohorts. Allergy, 68, 764-70.
- The National Asthma Council Australia (2019). Asthma Management Handbook.
- Toppila-Salmi, S., Huhtala, H., Karjalainen, J., Renkonen, R., Mäkelä, M. J., Wang, D. Y. ve Pekkanen, J. (2015). Sensitization pattern affects the asthma risk in Finnish adult population. Allergy, 70(9), 1112-1120.
- Türk Toraks Derneği (2016). Ulusal astım tanı ve tedavi rehberi. Toraks Dergisi, 4-31.
There are 12 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Araştırma Makalesi |
| Authors | |
| Publication Date | November 14, 2022 |
| Submission Date | December 24, 2021 |
| Acceptance Date | March 28, 2022 |
| Published in Issue | Year 2022 Volume: 10 Issue: 3 |
