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Differences In Helicobacter Pylori Colonizations Within Gastric Mucosa

Year 2010, Issue: 3, 159 - 161, 01.09.2010

Abstract

Purpose: H.pylori is a bacteria with a high affinity to the stomach and its colonization is limited to the gastric epithelium only. With time chronic superficial gastritis related to H.pylori infection can lead to the development of atrophic gastritis, therefore giving way to gastric corpus involvement. Hence, choosing the most appropriate and optimal biopsy location of H.pylori is gaining increasing importance. Thus, although H.pylori has a preference to colonize the gastric antrum initially, over time with the advancement age and/or the development of atrophic gastritis, a predominant gastric corpus settlement is observed. The purpose of this study was to compare the rate of H.pylori positivity from biopsies taken from the gastric antrum versus corpus

References

  • Hui PK, Chan WY, Cheung PS, Chan JK, Ng CS. Pathologic changes of gastric mucosa colonized by Helicobacter pylori. Hum Pathol. 1992 May;23(5):548–56.
  • Sachs G, Wen Y, Scott DR. Gastric infection by Helicobacter pylori. Curr Gastroenterol Rep. 2009 Dec;11(6):455-61. Review.
  • Graham DY, Sung JJY, Helicobacter pylori In: Sleisenger MH, Fordtran JS, Editors. Gastrointestinal and liver disease. 8th edition. Philadelphia. Saunders 2006: 1049-1088
  • Correa P, Piazuelo MB. Natural history of Helicobacter pylori infection. Dig Liver Dis. 2008 Jul;40(7):490-6.
  • Koskenpato J, Färkkilä M, Sipponen P. Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia. Scand J Gastroenterol. 2002 Jul;37(7):778-84.
  • Yousfi MM, Reddy R, Osato MS, Graham DY. Is antrum or corpus the best site for culture of Helicobacter pylori? Helicobacter. 1996 Jun;1(2):88-91.
  • Woo JS, el-Zimaity HM, Genta RM, Yousfi MM, Graham DY. The best gastric site for obtaining a positive rapid ureas test. Helicobacter. 1996 Dec;1(4):256-9.
  • Abasiyanik MF, Tunc M, Salih BA. Enzyme immunoassay and immunoblotting analysis of Helicobacter pylori infection in Turkish asymptomatic subjects. Diagn Microbiol Infect Dis. 2004 Nov;50(3):173-7.
  • Arslan E, Atilgan H, Yavaşoğlu I. The prevalence of Helicobacter pylori in obese subjects. Eur J Intern Med. 2009 Nov;20(7):695-7.
  • Yucel T, Aygin D, Sen S, Yucel O. The prevalence of Helicobacter pylori and related factors among university students in Turkey. Jpn J Infect Dis. 2008 May;61(3):179-83.
  • Demir M, Gokturk HS, Ozturk NA, Kulaksizoglu M, Serin E, Yilmaz U. Helicobacter pylori prevalence in diabetes mellitus patients with dyspeptic symptoms and its relationship to glycemic control and late complications. Dig Dis Sci. 2008 Oct;53(10):2646-9.
  • Kim CG, Choi IJ, Lee JY, Cho SJ, Nam BH, Kook MC et al. Biopsy site for detecting Helicobacter pylori infection in patients with gastric cancer. J Gastroenterol Hepatol. 2009 Mar;24(3):469-74.

Helikobakter Pilorinin Midede Yerleşim Yeri

Year 2010, Issue: 3, 159 - 161, 01.09.2010

Abstract

Amaç: Helikobakter pilori H.pilori gastrotropik bir bakteridir. Sadece mide epitelinde kolonize olabilir. Mide içerisinde yerleşim yeri; varlığını test etmek istediğimiz zaman daha da önem taşır. Kronik yüzeysel H.pilori gastriti zamanla atrofik gastrite sebep olur ve gastrit daha çok korpus baskın hale gelir. Böylece aslında antruma yerleşmeyi seven H.pilorinin yaş ilerledikçe veya atrofi geliştikçe korpusa yerleştiği düşünülmektedir. Bu çalışmanın amacı; hem antrum hem de korpustan biyopsi alınan ve H.pilorinin pozitif saptandığı hastalarda bakterinin yerleşim yerini araştırmaktır

References

  • Hui PK, Chan WY, Cheung PS, Chan JK, Ng CS. Pathologic changes of gastric mucosa colonized by Helicobacter pylori. Hum Pathol. 1992 May;23(5):548–56.
  • Sachs G, Wen Y, Scott DR. Gastric infection by Helicobacter pylori. Curr Gastroenterol Rep. 2009 Dec;11(6):455-61. Review.
  • Graham DY, Sung JJY, Helicobacter pylori In: Sleisenger MH, Fordtran JS, Editors. Gastrointestinal and liver disease. 8th edition. Philadelphia. Saunders 2006: 1049-1088
  • Correa P, Piazuelo MB. Natural history of Helicobacter pylori infection. Dig Liver Dis. 2008 Jul;40(7):490-6.
  • Koskenpato J, Färkkilä M, Sipponen P. Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia. Scand J Gastroenterol. 2002 Jul;37(7):778-84.
  • Yousfi MM, Reddy R, Osato MS, Graham DY. Is antrum or corpus the best site for culture of Helicobacter pylori? Helicobacter. 1996 Jun;1(2):88-91.
  • Woo JS, el-Zimaity HM, Genta RM, Yousfi MM, Graham DY. The best gastric site for obtaining a positive rapid ureas test. Helicobacter. 1996 Dec;1(4):256-9.
  • Abasiyanik MF, Tunc M, Salih BA. Enzyme immunoassay and immunoblotting analysis of Helicobacter pylori infection in Turkish asymptomatic subjects. Diagn Microbiol Infect Dis. 2004 Nov;50(3):173-7.
  • Arslan E, Atilgan H, Yavaşoğlu I. The prevalence of Helicobacter pylori in obese subjects. Eur J Intern Med. 2009 Nov;20(7):695-7.
  • Yucel T, Aygin D, Sen S, Yucel O. The prevalence of Helicobacter pylori and related factors among university students in Turkey. Jpn J Infect Dis. 2008 May;61(3):179-83.
  • Demir M, Gokturk HS, Ozturk NA, Kulaksizoglu M, Serin E, Yilmaz U. Helicobacter pylori prevalence in diabetes mellitus patients with dyspeptic symptoms and its relationship to glycemic control and late complications. Dig Dis Sci. 2008 Oct;53(10):2646-9.
  • Kim CG, Choi IJ, Lee JY, Cho SJ, Nam BH, Kook MC et al. Biopsy site for detecting Helicobacter pylori infection in patients with gastric cancer. J Gastroenterol Hepatol. 2009 Mar;24(3):469-74.
There are 12 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Arzu Tiftikçi

Bahattin Çiçek

Nesliar Eser Vardareli

Murat Saruç

Yeşim Sağlıcan

Nurdan Tözün

Publication Date September 1, 2010
Published in Issue Year 2010Issue: 3

Cite

EndNote Tiftikçi A, Çiçek B, Vardareli NE, Saruç M, Sağlıcan Y, Tözün N (September 1, 2010) Helikobakter Pilorinin Midede Yerleşim Yeri. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 3 159–161.