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GLIOBLASTOMA MULTIFORME WITH SPINAL SEEDING METASTASES

Year 2014, Issue: 3, 251 - 253, 01.09.2014

Abstract

Glioblastoma Multiforme GBM is the most common primary malignancy of the brain tumours with poor prognosis. Symptomatic spinal metastases are rarely seen in GBM patients. Herein we report 37 year old GBM case who has been diagnosed with concurrent spinal metastases and also risk factors for spinal seeding. In cases owning risk factors, the quality of life may improve with early spinal metastasis screening and early treatment

References

  • Fisher JL, Schwartzbaum JA, Wrensch M, Wiemels JL: Epidemiology of brain tumors. Neurologic Clinics 25: 867-890,2007
  • Stupp R, Hegi ME, Gilbert MR, Chakravarti A: Chemoradiotherapy in malignant glioma: Standard of care and future directions. J Clin Oncol 25:4127-4136, 2007
  • NgWH, Yeo TT, Kaye AH. Spinal and extracranialmetastatic dissemination of malignant glioma. J Clin Neurosci 2005;12:379–82.
  • Arita N, Taneda M, Hayakawa T. Leptomeningeal dissemination of malignant gliomas: Incidence, diagnosis and outcome. Acta Neurochir [Wien] 1994;126:84-92.
  • Vertosick FT, Jr, Selker RG. Brain stem and spinal metastases of supratentorial glioblastoma multiforme: a clinical series. Neurosurgery 1990;27:516–22.
  • Grabb PA, Albright AL, Pang D. Dissemination of supratentorial malignant gliomas via the cerebrospinal fluid in children. Neurosurgery 1992;30:64–71.
  • Onda K, Tanaka R, Takahashi H, Takeda N, Ikuta F. Cerebral glioblastoma with cerebrospinal fluid dissemination: a clinicopathological study of 14 cases examined by complete autopsy. Neurosurgery 1989;25:533–40.
  • Stanley P, Senac MO Jr, Segall HD. Intraspinal seeding from intracranial tumors in children. Am J Roentgenol 1985;144:157-61.
  • Beck DK, Russell DS. Oligodendrogliomatosis of the cerebrospinal pathway. Brain 1942;65:352–72.
  • Buhl R, Barth H, Hugo HH, et al. Spinal drop metastases in recurrent glioblastoma multiforme. Acta Neurochir (Wien) 1998;140:1001–5.
  • Grabb PA, Albright AL, Pang D. Dissemination of supratentorial malignant gliomas via the cerebrospinal fluid in children. Neurosurgery 1992;30:64–71.
  • Balhuizen JC, Bots GT, Schaberg A, Bosman FT. Value of cerebrospinal fluid cytology for the diagnosis of malignancies in the central nervous system. J Neurosurg 1978;48:747–53.

Spinal Ekilme Metastazlı Glioblastoma Multiforme Olgusu

Year 2014, Issue: 3, 251 - 253, 01.09.2014

Abstract

Glioblastoma Multiforme GBM tüm beyin tümorleri arasında en sık görülen kötü prognozlu bir tümordur. GBM hastalarında semptomatik spinal metastazlar nadir görülür. Bu yazıda 37 yaşında GBM tanısı ile eş zamanlı saptanan spinal ekilme metastazlı bir olgu ve spinal ekilme için risk faktörleri sunulmuştur. Risk faktörleri olan olgularda erken spinal görüntüleme ve erken tedavi ile bu hastaların hayat kalitesi arttırılabilir

References

  • Fisher JL, Schwartzbaum JA, Wrensch M, Wiemels JL: Epidemiology of brain tumors. Neurologic Clinics 25: 867-890,2007
  • Stupp R, Hegi ME, Gilbert MR, Chakravarti A: Chemoradiotherapy in malignant glioma: Standard of care and future directions. J Clin Oncol 25:4127-4136, 2007
  • NgWH, Yeo TT, Kaye AH. Spinal and extracranialmetastatic dissemination of malignant glioma. J Clin Neurosci 2005;12:379–82.
  • Arita N, Taneda M, Hayakawa T. Leptomeningeal dissemination of malignant gliomas: Incidence, diagnosis and outcome. Acta Neurochir [Wien] 1994;126:84-92.
  • Vertosick FT, Jr, Selker RG. Brain stem and spinal metastases of supratentorial glioblastoma multiforme: a clinical series. Neurosurgery 1990;27:516–22.
  • Grabb PA, Albright AL, Pang D. Dissemination of supratentorial malignant gliomas via the cerebrospinal fluid in children. Neurosurgery 1992;30:64–71.
  • Onda K, Tanaka R, Takahashi H, Takeda N, Ikuta F. Cerebral glioblastoma with cerebrospinal fluid dissemination: a clinicopathological study of 14 cases examined by complete autopsy. Neurosurgery 1989;25:533–40.
  • Stanley P, Senac MO Jr, Segall HD. Intraspinal seeding from intracranial tumors in children. Am J Roentgenol 1985;144:157-61.
  • Beck DK, Russell DS. Oligodendrogliomatosis of the cerebrospinal pathway. Brain 1942;65:352–72.
  • Buhl R, Barth H, Hugo HH, et al. Spinal drop metastases in recurrent glioblastoma multiforme. Acta Neurochir (Wien) 1998;140:1001–5.
  • Grabb PA, Albright AL, Pang D. Dissemination of supratentorial malignant gliomas via the cerebrospinal fluid in children. Neurosurgery 1992;30:64–71.
  • Balhuizen JC, Bots GT, Schaberg A, Bosman FT. Value of cerebrospinal fluid cytology for the diagnosis of malignancies in the central nervous system. J Neurosurg 1978;48:747–53.
There are 12 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Bilgehan Şahin

Banu Atalar

Ercan Karaarslan

Enis Özyar

Publication Date September 1, 2014
Published in Issue Year 2014Issue: 3

Cite

EndNote Şahin B, Atalar B, Karaarslan E, Özyar E (September 1, 2014) Spinal Ekilme Metastazlı Glioblastoma Multiforme Olgusu. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 3 251–253.