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Methotrexate Treatment of Cornual Pregnancy With Fetal Cardiac Activity: a Case Report and Review of Literature

Year 2015, Issue: 1, 46 - 48, 01.03.2015

Abstract

Cornual pregnancy is a rare type of ectopic pregnacy, it has the highest mortality-morbidity among ectopic pregnancies. Since there is no optimal treatment stategy or consensus, there is only sharing of experiences with case or cases series reports. In this paper, a 21 year old woman, G:2, P:1, A:0 with right cornual pregnancy was presented. Although fetal cardiac activity was positive, two doses of methotrexate treatment were given since the patient wanted to preserve her fertility. There were no treatment complications. The aim of this paper was to discuss the diagnosis and treatment protocols of cornual pregnancy regarding this case

References

  • Peterson HB. Extratubal ectopic pregnancies. Diagnosis and treatment. J Reprod Med 1986;31:108-15.
  • Lau S,Tulandi T. Conservative medical and surgical management of cornual ectopic pregnancy. Fertil Steril 1999;72:207-15.
  • Tulandi T, AI Jaroudi D. Interstistial pregnancy: results generated from the society of reproductive surgeons registry. Obstet Gynecol 2004;103:47-50.
  • İtil İM, Çırpan T, Biler A, Yücebilgin S. Kornual gebelik tedavisinde histeroskopi ve vakum aspirasyonu: olgu sunumu J Turk Soc Obstet Gynecol 2007;4:121-124.
  • Ackerman TE, Levi CS, Dashefsky SM, Holt SC, Lindsay DJ. An interstitial line; sonographic finding in an interstitial (cornual) ectopic pregnancy. Radiology 1993;189: 83-87.
  • Timor- Tritsch IE, Montegudo A, Matera C et al. Sonographic evaluation of cornual pregnancies treated without surgery. Obstet Gynecol 1992;79:1044-9.
  • Fisch JD, Ortiz B, Tazuke S, Chitkara U, Giudice L. Medical management of interstistial ectopic pregnancy : a case report adn literature review. Hum Reprod 1998;13:1981-1986.
  • Jermy K, Thomas J, Doo A, Bourne T. The conservative management of cornual pregnancy BJOG 2004;111:1283-8.
  • Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual pregnancy with a single methotrexate injection. A report of 3 cases. J Reprod Med 2005; 50: 141-4.
  • Green Top Guideline No. 21. London, UK:RCOG; 2004 . Royal College of Obstetricians and Gynaecologists. The Management of Tubal Pregnancy. www.rcog.org.uk/index.asp. PageID=537) .

Fetal Kardiyak Aktivitesi Olan Kornual Gebeliğin Metotreksat ile Tedavisi: Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Year 2015, Issue: 1, 46 - 48, 01.03.2015

Abstract

Kornual gebelik mortalite-morbiditesi en yüksek olan ve nadir görülen ektopik gebelik türüdür. Optimal tedavi konusunda fikir birliği olmayıp, literatürde vaka takdimi ya da vaka serileri şeklinde tecrübe paylaşımı söz konusudur. Erken tanı ve tedavi hastanın sağ kalımı ve fertilitenin korunması açısından önemlidir. Bu yazıda, 21 yaşında, G:2, P:1, A:0, sağ kornual gebeliği olan bir olgu sunulmuştur. Fetal kardiyak aktivite olmasına rağmen, hastanın fertilitesini koruma isteğinden dolayı, iki doz sistemik metotreksat uygulanarak tedavisi gerçekleştirilmiştir . Tedavi sonucunda herhangi bir komplikasyonla karşılaşılmamıştır. Bu vaka ışığında, kornual gebeliklerde tanı ve sistemik metotreksat tedavi protokollerinin tartışılması amaçlanmıştır

References

  • Peterson HB. Extratubal ectopic pregnancies. Diagnosis and treatment. J Reprod Med 1986;31:108-15.
  • Lau S,Tulandi T. Conservative medical and surgical management of cornual ectopic pregnancy. Fertil Steril 1999;72:207-15.
  • Tulandi T, AI Jaroudi D. Interstistial pregnancy: results generated from the society of reproductive surgeons registry. Obstet Gynecol 2004;103:47-50.
  • İtil İM, Çırpan T, Biler A, Yücebilgin S. Kornual gebelik tedavisinde histeroskopi ve vakum aspirasyonu: olgu sunumu J Turk Soc Obstet Gynecol 2007;4:121-124.
  • Ackerman TE, Levi CS, Dashefsky SM, Holt SC, Lindsay DJ. An interstitial line; sonographic finding in an interstitial (cornual) ectopic pregnancy. Radiology 1993;189: 83-87.
  • Timor- Tritsch IE, Montegudo A, Matera C et al. Sonographic evaluation of cornual pregnancies treated without surgery. Obstet Gynecol 1992;79:1044-9.
  • Fisch JD, Ortiz B, Tazuke S, Chitkara U, Giudice L. Medical management of interstistial ectopic pregnancy : a case report adn literature review. Hum Reprod 1998;13:1981-1986.
  • Jermy K, Thomas J, Doo A, Bourne T. The conservative management of cornual pregnancy BJOG 2004;111:1283-8.
  • Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual pregnancy with a single methotrexate injection. A report of 3 cases. J Reprod Med 2005; 50: 141-4.
  • Green Top Guideline No. 21. London, UK:RCOG; 2004 . Royal College of Obstetricians and Gynaecologists. The Management of Tubal Pregnancy. www.rcog.org.uk/index.asp. PageID=537) .
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Onur Numan

Nurettin Aka

Fisun Vural

Ayşe Deniz Coşkun

Gültekin Köse

Ertuğrul Can Tüfekçi

Publication Date March 1, 2015
Published in Issue Year 2015Issue: 1

Cite

EndNote Numan O, Aka N, Vural F, Coşkun AD, Köse G, Tüfekçi EC (March 1, 2015) Fetal Kardiyak Aktivitesi Olan Kornual Gebeliğin Metotreksat ile Tedavisi: Olgu Sunumu ve Literatürün Gözden Geçirilmesi. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 1 46–48.