Is Gamma-Glutamyl Transferase Elevation Associated With Cardiac Failure In Infants With Ventricular Septal Defect?

Number: 2 June 1, 2020
  • Fatih Aygün
  • Ahmet İrdem
EN TR

Is Gamma-Glutamyl Transferase Elevation Associated With Cardiac Failure In Infants With Ventricular Septal Defect?

Abstract

Purpose/Aim: Ventricular septal defect VSD which is the most common cause of congenital heart defects in children, can lead to heart failure 6–8 weeks after birth due to the decrease in the pulmonary vascular resistance. The clinical features of cardiac failure can be subtle during the infant period, so the laboratory parameters can help the diagnosis and the follow-up. The relation between gamma-glutamyl transferase GGT and cardiac failure is reported in adults. Herein, we aimed to evaluate the relationship between liver enzymes especially GGT levels and cardiac failure developing due to VSD in pediatric patients

Keywords

References

  1. 1. Bernstein D. Congenital heart disease. In: Behrman RE, Kliegman RM, Jenson HB, editors. Nelson Textbook of Pediatrics, 17th ed. Philadelphia: Saunders; 2004. p.1499–554.
  2. 2. Hoffman JIE, Kaplan S, Liberthson RR. Prevalence of congenital heart disease. Am Heart J 2004;147:425–39. [CrossRef]
  3. 3. Zan S, Yapıcıoğlu H, Erdem S, Özlü F, Satar M, Özbarlas N ve ark. Çukurova Üniversitesi Tıp Fakültesi Hastanesi yenidoğan yoğun bakım ünitelerinde son beş yılda izlenen konjenital kalp hastalarının retrospektif incelenmesi. Çocuk Sağlığı ve Hastalıkları Derg 2015;58:7–16. http://www.cshd.org.tr/uploads/pdf_CSH_554.pdf
  4. 4. Ekici F, Ünal S, Dablan S, Alpan N, Çevik B, Vidinlisan S. Yenidoğan yoğun bakım ünitesindeki 119 bebeğin klinik ve ekokardiyografik değerlendirilmesi. Türkiye Çocuk Hastalıkları Derg 2010;4:22–9. https://dergipark.org.tr/tr/download/article-file/689238
  5. 5. Azak E, Ünsal H, Kibar AE, Çetin İİ. Çocuklarda Konjestif Kalp Yetersizliği. Türkiye Çocuk Hastalıkları Dergisi 2016;3:223–32. [CrossRef]
  6. 6. Masarone D, Valente F, Rubino M, Vastarella R, Gravino R, Rea A, et al. Pediatric Heart Failure: A Practical Guide to Diagnosis and Management. Pediatr Neonatol 2017;58:303–12. [CrossRef]
  7. 7. Ko KH, Lee JH, Choi BM, Lee JH, Yoo KH, Son CS, Lee JW. Utility of the rapid B-type natriuretic peptide assay for detection of cardiovascular problems in newborn infants with respiratory difficulties. Neonatalogy 2008;94:16–21. [CrossRef]
  8. 8. Auslender M. Pathophysiology of pediatric heart failure. Progress Pediatr Cardiol 2000;11:175–84. [CrossRef]

Details

Primary Language

Turkish

Subjects

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Journal Section

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Authors

Fatih Aygün

Ahmet İrdem

Publication Date

June 1, 2020

Submission Date

-

Acceptance Date

-

Published in Issue

Year 1970 Number: 2

EndNote
Aygün F, İrdem A (June 1, 2020) Ventriküler Septal Defekti Olan Bebeklerde Gama-Glutamil Transferaz Yüksekliği Kalp Yetersizliği ile İlişkili midir? Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2 284–288.