Abstract
Aralık 2019'da Çin'in Wuhan kentinden kaynaklandığı düşünülen ve milyonlarca kişinin enfekte olmasına neden olan koronavirus bir pandemiye yol açmıştır. Enfeksiyonun ilk dönemlerinde sıklıkla görülen semptomlar ateş, miyalji ve öksürük olarak bildirilmiştir. Biz bu yazıda başlangıç bulguları olarak sadece koku ve tat alma fonksiyonunda kaybolma şikayeti ile gelen iki hastayı inceledik. Testleri pozitif çıkan ve pnömoni tanısı konan hastalarda öksürük ve ateş görülmedi. Sadece tat ve koku duyularının kaybolduğu hastaların mutlaka test ile taranması gerektiğini düşünmekteyiz.
References
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- [2] Huang C1, Wang Y2, Li X3, Ren L4, Zhao J5, Hu Y6, Zhang L1, Fan G7, Xu J8, Gu X7, Cheng Z9, Yu T1, Xia J1, Wei Y1, Wu W1, Xie X1, Yin W6, Li H2, Liu M10, Xiao Y4, Gao H11, Guo L4, Xie J5, Wang G12, Jiang R3, Gao Z13, Jin Q4, Wang J14, Cao B15Clinical features of patientsinfectedwith 2019 novelcoronavirus in Wuhan, China..Lancet. 2020 Feb 15;395(10223):497-506.
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- [4] Identification of Viruses in PatientsWithPostviralOlfactoryDysfunctionMotohiko Suzuki, MD; KoichiSaito, BS; Wei-PingMin, MD; CostinVladau, BS; KazunoriToida, MD; HirotakaItoh, MD; ShingoMurakami, MD Laryngoscope, 117:272–277, 2007
- [5] Stroop MG. Virusesandtheolfactorysystem. In: Doty RL, editor. Handbook of olfactionandgustation. New York: MarcelDekker; 1995. p. 367–94
- [6] Yamagishi M, Fujiwara M, Nakamura H. Olfactorymucosalfindingsandclinicalcourse in patientswitholfactorydisordersfollowingupperrespiratoryviralinfection. Rhinology1994;32:113–8
- [7] Perlman S, Evans G, Afifi A. Effect of olfactorybulbablation on spread of a neurotropiccoronavirusintothemousebrain. J ExpMed1990;172:1127–32
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- [9] An SS, Liggett SB. TasteandsmellGPCRs in thelung: evidenceforapreviouslyunrecognizedwidespreadchemosensorysystem. Cell Signal. 2018;41:82-88. doi:10.1016/j.cellsig.2017.02.002
Abstract
The coronavirus assumed to have originated in Wuhan China, has infected millions of people since December 2019, resulting in a pandemic. Recent changes in symptoms are observed in Covid-19 positive patients, whose symptoms were reported as fever, myalgia and cough in the earlier cases. In this paper we presented two cases where the initial symptom was loss of taste and smell sensation. Both of these patients were diagnosed pneumonia though neither of them had cough nor fever.Considering the positive outcomes with medical treatment, we claim these patients with the only symptom, loss of smell and taste, should be tested for Covid-19.
References
- [1] Mahony JB, Petrich A, Smieja M. Moleculardiagnosis of respiratoryvirusinfections. CritRevClinLabSci. 2011;48:217-49.
- [2] Huang C1, Wang Y2, Li X3, Ren L4, Zhao J5, Hu Y6, Zhang L1, Fan G7, Xu J8, Gu X7, Cheng Z9, Yu T1, Xia J1, Wei Y1, Wu W1, Xie X1, Yin W6, Li H2, Liu M10, Xiao Y4, Gao H11, Guo L4, Xie J5, Wang G12, Jiang R3, Gao Z13, Jin Q4, Wang J14, Cao B15Clinical features of patientsinfectedwith 2019 novelcoronavirus in Wuhan, China..Lancet. 2020 Feb 15;395(10223):497-506.
- [3]Detection of parainfluenzavirus 3 in turbinateepithelialcells of postviralolfactorydysfunctionpatients.Wang JH1, Kwon HJ, Jang YJ. Laryngoscope. 2007 Aug;117(8):1445-9.
- [4] Identification of Viruses in PatientsWithPostviralOlfactoryDysfunctionMotohiko Suzuki, MD; KoichiSaito, BS; Wei-PingMin, MD; CostinVladau, BS; KazunoriToida, MD; HirotakaItoh, MD; ShingoMurakami, MD Laryngoscope, 117:272–277, 2007
- [5] Stroop MG. Virusesandtheolfactorysystem. In: Doty RL, editor. Handbook of olfactionandgustation. New York: MarcelDekker; 1995. p. 367–94
- [6] Yamagishi M, Fujiwara M, Nakamura H. Olfactorymucosalfindingsandclinicalcourse in patientswitholfactorydisordersfollowingupperrespiratoryviralinfection. Rhinology1994;32:113–8
- [7] Perlman S, Evans G, Afifi A. Effect of olfactorybulbablation on spread of a neurotropiccoronavirusintothemousebrain. J ExpMed1990;172:1127–32
- [8] Behaviouraldeficitsandserotonindepletion in adultratsaftertransientinfantnasalviralinfection. Mohammed AK1, Magnusson O, Maehlen J, Fonnum F, Norrby E, Schultzberg M, Kristensson K. Neuroscience. 1990;35(2):355-63.
- [9] An SS, Liggett SB. TasteandsmellGPCRs in thelung: evidenceforapreviouslyunrecognizedwidespreadchemosensorysystem. Cell Signal. 2018;41:82-88. doi:10.1016/j.cellsig.2017.02.002
Details
| Primary Language | English |
|---|---|
| Subjects | Otorhinolaryngology |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | July 1, 2021 |
| Submission Date | May 13, 2020 |
| Published in Issue | Year 2021Volume: 12 Issue: 3 |
