Abstract
References
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Abstract
IS IT REALLY NECESSARY TO PERFORM COLPOSCOPY IN PATIENTS WITH ASCUS AND HR HPV POSITIVITY?
INTRODUCTION:
Papanicolaou (Pap) smear is a very important screening method for detection of cervİcal cancer or cell changes that can lead to it. Atypical squamous cells of undetermined significance (ASCUS) is the most common abnormality seen among all cervical cytologies with the percentage of 4-5% . Human papillomavirus (HPV) infection is regarded as a major cause of cervical intraepithelial neoplasia (CIN) and cervical cancer.
Colposcopy is recommended for all women with high-grade squamous intraepithelial lesion (HSIL) and atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion (ASC-H) for cervical cancer screening . It is also recommended for high-risk HPV (HR HPV) positive women with ASCUS.
The aim of this study is to evaluate the importance of colposcopy in patients with ASCUS and HR HPV positivity.
MATERIALS AND METHODS:
Study Population
We performed a retrospective study approved by the ethics committee of Acıbadem University. Women with diagnosis of ASCUS and HR HPV positivity who underwent colposcopic evaluation at 2 different gynecologic oncology clinics of our university from January 2011 to January 2019 were included in our study. The age range was from 21 to 48 and the mean age of patients’ was 29. Subjects who were pregnant, hysterectomized or had previous cytological abnormalities were excluded.
CONCLUSION:
In this study, we aimed to evaluate the significance of colposcopy in patients with ASCUS and high-risk HPV positivity, especially strains 16 and 18. As mentioned in some other studies, immediate colposcopy is an expensive screening procedure for further evaluation of ASCUS .
Keywords
References
- 1-Cheng JX, Yao LL, Xiang H, Zhan YJ, Zhou P, Yuan M, Mei LP, Zhang Y.Clin Exp Obstet Gynecol. 2016;43(4):592-596.
- 2-Aydogan Kirmizi D, Baser E, Demir Caltekin M, Onat T, Sahin S, Yalvac ES.Diagn Cytopathol. 2021 Jan;49(1):132-139. doi: 10.1002/dc.24655. Epub 2020 Oct 29.
- 3-Arbyn M, Roelens J, Simoens C, Buntinx F, Paraskevaidis E, Martin-Hirsch PP, Prendiville WJ.Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD008054.
- 4-Koliopoulos G, Nyaga VN, Santesso N, Bryant A, Martin-Hirsch PP, Mustafa RA, Schünemann H, Paraskevaidis E, Arbyn M.Cochrane Database Syst Rev. 2017 Aug 10;8(8):CD008587. doi: 10.1002/14651858.CD008587.pub2.
- 5-Schiffman M, Doorbar J, Wentzensen N, de Sanjosé S, Fakhry C, Monk BJ, Stanley MA, Franceschi S.Nat Rev Dis Primers. 2016 Dec 1;2:16086. doi: 10.1038/nrdp.2016.86.
- 6-Marujo AT, Correia L, Brito M, Paula T, Borrego J.J Am Soc Cytopathol. 2017 Nov-Dec;6(6):248-253. doi: 10.1016/j.jasc.2017.07.004. Epub 2017 Aug 4.
- 7-Arbyn M, Roelens J, Simoens C, Buntinx F, Paraskevaidis E, Martin-Hirsch PP, Prendiville WJ.Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD008054. doi: 10.1002/14651858.CD008054.pub2.
- 8-Muñoz N, Bosch FX, de Sanjosé S, Herrero R, Castellsagué X, Shah KV, Snijders PJ, Meijer CJ; International Agency for Research on Cancer Multicenter Cervical Cancer Study Group.N Engl J Med. 2003 Feb 6;348(6):518-27. doi: 10.1056/NEJMoa021641
- 9-Buskwofie A, David-West G, Clare CA.J Natl Med Assoc. 2020 Apr;112(2):229-232. doi: 10.1016/j.jnma.2020.03.002. Epub 2020 Apr 8.
- 10-Kalliala I, Athanasiou A, Veroniki AA, Salanti G, Efthimiou O, Raftis N, Bowden S, Paraskevaidi M, Aro K, Arbyn M, Bennett P, Nieminen P, Paraskevaidis E, Kyrgiou M.Ann Oncol. 2020 Feb;31(2):213-227. doi: 10.1016/j.annonc.2019.11.004. Epub 2020 Jan 3.
- 11-Polman NJ, Veldhuijzen NJ, Heideman DAM, Snijders PJF, Meijer CJLM, Berkhof J.Int J Cancer. 2019 May 1;144(9):2339-2346. doi: 10.1002/ijc.32004. Epub 2019 Jan 10.
- 12-Ferris DG, Wright TC Jr, Litaker MS, Richart RM, Lorincz AT, Sun XW, Borgatta L, Buck H, Kramer L, Rubin R.J Fam Pract. 1998 Feb;46(2):125-34.
Details
| Primary Language | English |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Research Article |
| Authors | |
| Publication Date | October 1, 2022 |
| Submission Date | June 29, 2022 |
| Published in Issue | Year 2022Volume: 13 Issue: 4 |
