Research Article
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Year 2025, Volume: 16 Issue: 2, 233 - 239, 10.04.2025

Mübeccel Bulut , Ayşe Sevgi Karadağ

https://doi.org/10.31067/acusaglik.1409550

Abstract

References

  • 1. Shah S, Laiquzzaman M, Cunliffe I, Mantry S. The use of the Reichert ocular response analyser to establish the relationship between ocular hysteresis, corneal resistance factor and central corneal thickness in normal eyes. Contact Lens Anterior Eye. 2006 Dec;29(5):257–62. DOI:10.1016/j.clae.2006.09.006
  • 2. McMahon TiT, Polse KA, McNamara N, Viana MAG. Recovery from Induced Corneal Edema and Endothelial Morphology after Long-Term PMMA Contact Lens Wear. Optom Vis Sci. 1996 Mar;73(3):184–8. DOI:10.1097/00006324-199603000-00010
  • 3. Bergmanson JP, Chu LW. Corneal response to rigid contact lens wear. Br J Ophthalmol. 1982 Oct 1;66(10):667–75. DOI:10.1136/bjo.66.10.667
  • 4. Thoft RA. Corneal Glucose Flux. Arch Ophthalmol. 1971 Dec 1;86(6):685. DOI:10.1001/archopht.1971.01000010687013
  • 5. Heitz RF. History of contact lenses. In: CLAO Guide to Basic Science and Clinical Practice. Boston, MA: Little Brown&Co; 1984. p. 667–75.
  • 6. McMahon TT, Zadnik K. Twenty-five Years of Contact Lenses. Cornea. 2000 Sep;19(5):730–40. DOI:10.1097/00003226-200009000-00018
  • 7. Temel A. Sert Kontakt Lensler (Materyal, Tasarım, Uygulama). MN Oftalmol. 1994;(1):21–4.
  • 8. Pastewski B, Lee A. Contact Lens Care (Part 1). Am Drug. 1985;192:117–39.
  • 9. Engle J. Contact Lens Care. Am Drug. 1990;201(1):54–65.
  • 10. Geleneksel Kontakt Lensler, Kontakt Lensler ve Uygulanması. TOD Eğitim Yayınları-4. 2005;69–92.
  • 11. Dillehay SM. Does the Level of Available Oxygen Impact Comfort in Contact Lens Wear?: A Review of the Literature. Eye Contact Lens Sci Clin Pract. 2007 May;33(3):148–55. DOI:10.1097/01.icl.0000245572.66698.b1
  • 12. Holden BA, Mertz GW. Critical oxygen levels to avoid corneal edema for daily and extended wear contact lenses. Invest Ophthalmol Vis Sci. 1984 Oct;25(10):1161–7.
  • 13. Lee JS, Park WS, Lee SH, Oum BS, Cho BM. A comparative study of corneal endothelial changes induced by different durations of soft contact lens wear. Graefe’s Arch Clin Exp Ophthalmol. 2001 Jan;239(1):1–4. DOI:10.1007/s004170000223
  • 14. Schornack M. Hydrogel contact lens-induced corneal warpage. Contact Lens Anterior Eye. 2003 Sep;26(3):153–9. DOI:10.1016/S1367-0484(03)00026-2
  • 15. Collins MJ, Buehren T, Trevor T, Statham M, Hansen J, Cavanagh DA. Factors Influencing Lid Pressure on the Cornea. Eye Contact Lens Sci Clin Pract. 2006 Jul;32(4):168–73. DOI:10.1097/01.icl.0000189193.28870.81
  • 16. Radaie-Moghadam S, Hashemi H, Jafarzadehpur E, Yekta A, Khabazkhoob M. Corneal biomechanical changes following toric soft contact lens wear. J Ophthalmic Vis Res. 2016;11(2):131. DOI:10.4103/2008-322X.183921
  • 17. Yıldız Y, Gürdal C, Saraç Ö, Nacaroğlu ŞA, Takmaz T, Can İ. The Long Term Effects of Silicone Hydrogel Contact Lens Wearing on Corneal Morphology. TJO. 2012;42(2):91–6.
  • 18. Liu Z, Pflugfelder SC. The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity 1 1The authors have no proprietary interest in any of the products or equipment mentioned in this article. Ophthalmology. 2000 Jan;107(1):105–11. DOI:10.1016/S0161-6420(99)00027-5
  • 19. Ruiz-Montenegro J, Mafra CH, Wilson SE, Jumper JM, Klyce SD, Mendelson EN. Corneal Topographic Alterations in Normal Contact Lens Wearers. Ophthalmology. 1993 Jan;100(1):128–34. DOI:10.1016/S0161-6420(93)31704-5
  • 20. Alba-Bueno F, Beltran-Masgoret À, Sanjuan C, Biarnés M, Marín J. Corneal shape changes induced by first and second generation silicone hydrogel contact lenses in daily wear. Contact Lens Anterior Eye. 2009 Apr;32(2):88–92. DOI:10.1016/j.clae.2008.11.002
  • 21. Gonzalez-Meijome JM, Gonzalez-Perez J, Cervino A, Yebra-Pimentel E, Parafita MA. Changes in Corneal Structure with Continuous Wear of High-Dk Soft Contact Lenses: A Pilot Study. Optom Vis Sci. 2003 Jun;80(6):440–6. DOI:10.1097/00006324-200306000-00010
  • 22. Nourouzi H, Rajavi J, Okhovatpour MA. Time to Resolution of Corneal Edema After Long-Term Contact Lens Wear. Am J Ophthalmol. 2006 Oct;142(4):671–3. DOI:10.1016/j.ajo.2006.04.061
  • 23. Chalmers R, Long B, Dillehay S, Begley C. Improving Contact-Lens Related Dryness Symptoms with Silicone Hydrogel Lenses. Optom Vis Sci. 2008 Aug;85(8):778–84. DOI:10.1097/OPX.0b013e318181a90d
  • 24. Sheng H, Bullimore MA. Factors Affecting Corneal Endothelial Morphology. Cornea. 2007 Jun;26(5):520–5. DOI:10.1097/ICO.0b013e318033a6da
  • 25. Farrell RA, Hart RW. On the theory of the spatial organization of macromolecules in connective tissue. Bull Math Biophys. 1969 Dec;31(4):727–60. DOI:10.1007/BF02477784
  • 26. Kettesy B, Vardai J, Berta A, Modis L, Kemeny-Beke A. A survey of corneal changes caused by daily wear silicone hydrogel contact lenses. J Innov Opt Health Sci. 2015 Nov 27;08(06):1550044. DOI:10.1142/S1793545815500443

INVESTIGATION OF CORNEAL CHANGES IN CONTACT LENS USERS

Year 2025, Volume: 16 Issue: 2, 233 - 239, 10.04.2025

Mübeccel Bulut , Ayşe Sevgi Karadağ

https://doi.org/10.31067/acusaglik.1409550

Abstract

Purpose: Analysed the effects of contact lens use on the structural characteristics of the cornea.
Methods: 95 patients using contact lens and 95 patient without ocular pathology were included in the study. Detailed ophthalmologic examinations were performed. Stromal and epithelial thicknes measured by OCT. CCT (central corneal thickness) and keratometry values were measured with topography. Endothelial values were measured using specular microscope. Schirmer test was performed.
Result: 21 of the lens users were male and 74 female, while 23 of the control subjects were male and 72 female. The mean age of Group 1 was 22.80 and 23.80 was 2. Topography values; K1, k2, posterior k2 is different, posterior k1 was similar. Epithelial thickness, the number of endothelial cells and their density were found to be different and age, gender , schirmer, CCT, stromal thickness and hexagonal cell counts were similar. Group 3, 0-18 months lens users and Group 4 consisted of contact lens users for more than 18 months. The ratio of group 3 between 0-18 months was 50.5% and 49.5% group 4. The mean age of Group 3 was 21.52 ± 3.31, 24.19 ± 4.99 in Group 4. When subgrouped according to duration, observed that sim k1, sim k2, cct, posterior k1 and posterior k2 values did not change, but the endothelial cell numbers were statistically different between subgroups.
Conclusion: Use of high permeability silicon hydrogel lenses some of the hypoxic effects of the contact lenses on the corneal structure in relation to the mechanical and inflammatory activity is still present. Due to recently increased use of lenses and desire of patients for keratorefractive surgery, it must known the effects of the corneal structures to prevent surgical complications and meet the expectations of the patients with respect to these surgeries.

Keywords

Contackt lens Anterior Segment OCT Sirius Topography Specular Microscopy

Ethical Statement

Adıyaman üniversitesinde etik kurul alınmıştır

Supporting Institution

yoktur

References

  • 1. Shah S, Laiquzzaman M, Cunliffe I, Mantry S. The use of the Reichert ocular response analyser to establish the relationship between ocular hysteresis, corneal resistance factor and central corneal thickness in normal eyes. Contact Lens Anterior Eye. 2006 Dec;29(5):257–62. DOI:10.1016/j.clae.2006.09.006
  • 2. McMahon TiT, Polse KA, McNamara N, Viana MAG. Recovery from Induced Corneal Edema and Endothelial Morphology after Long-Term PMMA Contact Lens Wear. Optom Vis Sci. 1996 Mar;73(3):184–8. DOI:10.1097/00006324-199603000-00010
  • 3. Bergmanson JP, Chu LW. Corneal response to rigid contact lens wear. Br J Ophthalmol. 1982 Oct 1;66(10):667–75. DOI:10.1136/bjo.66.10.667
  • 4. Thoft RA. Corneal Glucose Flux. Arch Ophthalmol. 1971 Dec 1;86(6):685. DOI:10.1001/archopht.1971.01000010687013
  • 5. Heitz RF. History of contact lenses. In: CLAO Guide to Basic Science and Clinical Practice. Boston, MA: Little Brown&Co; 1984. p. 667–75.
  • 6. McMahon TT, Zadnik K. Twenty-five Years of Contact Lenses. Cornea. 2000 Sep;19(5):730–40. DOI:10.1097/00003226-200009000-00018
  • 7. Temel A. Sert Kontakt Lensler (Materyal, Tasarım, Uygulama). MN Oftalmol. 1994;(1):21–4.
  • 8. Pastewski B, Lee A. Contact Lens Care (Part 1). Am Drug. 1985;192:117–39.
  • 9. Engle J. Contact Lens Care. Am Drug. 1990;201(1):54–65.
  • 10. Geleneksel Kontakt Lensler, Kontakt Lensler ve Uygulanması. TOD Eğitim Yayınları-4. 2005;69–92.
  • 11. Dillehay SM. Does the Level of Available Oxygen Impact Comfort in Contact Lens Wear?: A Review of the Literature. Eye Contact Lens Sci Clin Pract. 2007 May;33(3):148–55. DOI:10.1097/01.icl.0000245572.66698.b1
  • 12. Holden BA, Mertz GW. Critical oxygen levels to avoid corneal edema for daily and extended wear contact lenses. Invest Ophthalmol Vis Sci. 1984 Oct;25(10):1161–7.
  • 13. Lee JS, Park WS, Lee SH, Oum BS, Cho BM. A comparative study of corneal endothelial changes induced by different durations of soft contact lens wear. Graefe’s Arch Clin Exp Ophthalmol. 2001 Jan;239(1):1–4. DOI:10.1007/s004170000223
  • 14. Schornack M. Hydrogel contact lens-induced corneal warpage. Contact Lens Anterior Eye. 2003 Sep;26(3):153–9. DOI:10.1016/S1367-0484(03)00026-2
  • 15. Collins MJ, Buehren T, Trevor T, Statham M, Hansen J, Cavanagh DA. Factors Influencing Lid Pressure on the Cornea. Eye Contact Lens Sci Clin Pract. 2006 Jul;32(4):168–73. DOI:10.1097/01.icl.0000189193.28870.81
  • 16. Radaie-Moghadam S, Hashemi H, Jafarzadehpur E, Yekta A, Khabazkhoob M. Corneal biomechanical changes following toric soft contact lens wear. J Ophthalmic Vis Res. 2016;11(2):131. DOI:10.4103/2008-322X.183921
  • 17. Yıldız Y, Gürdal C, Saraç Ö, Nacaroğlu ŞA, Takmaz T, Can İ. The Long Term Effects of Silicone Hydrogel Contact Lens Wearing on Corneal Morphology. TJO. 2012;42(2):91–6.
  • 18. Liu Z, Pflugfelder SC. The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity 1 1The authors have no proprietary interest in any of the products or equipment mentioned in this article. Ophthalmology. 2000 Jan;107(1):105–11. DOI:10.1016/S0161-6420(99)00027-5
  • 19. Ruiz-Montenegro J, Mafra CH, Wilson SE, Jumper JM, Klyce SD, Mendelson EN. Corneal Topographic Alterations in Normal Contact Lens Wearers. Ophthalmology. 1993 Jan;100(1):128–34. DOI:10.1016/S0161-6420(93)31704-5
  • 20. Alba-Bueno F, Beltran-Masgoret À, Sanjuan C, Biarnés M, Marín J. Corneal shape changes induced by first and second generation silicone hydrogel contact lenses in daily wear. Contact Lens Anterior Eye. 2009 Apr;32(2):88–92. DOI:10.1016/j.clae.2008.11.002
  • 21. Gonzalez-Meijome JM, Gonzalez-Perez J, Cervino A, Yebra-Pimentel E, Parafita MA. Changes in Corneal Structure with Continuous Wear of High-Dk Soft Contact Lenses: A Pilot Study. Optom Vis Sci. 2003 Jun;80(6):440–6. DOI:10.1097/00006324-200306000-00010
  • 22. Nourouzi H, Rajavi J, Okhovatpour MA. Time to Resolution of Corneal Edema After Long-Term Contact Lens Wear. Am J Ophthalmol. 2006 Oct;142(4):671–3. DOI:10.1016/j.ajo.2006.04.061
  • 23. Chalmers R, Long B, Dillehay S, Begley C. Improving Contact-Lens Related Dryness Symptoms with Silicone Hydrogel Lenses. Optom Vis Sci. 2008 Aug;85(8):778–84. DOI:10.1097/OPX.0b013e318181a90d
  • 24. Sheng H, Bullimore MA. Factors Affecting Corneal Endothelial Morphology. Cornea. 2007 Jun;26(5):520–5. DOI:10.1097/ICO.0b013e318033a6da
  • 25. Farrell RA, Hart RW. On the theory of the spatial organization of macromolecules in connective tissue. Bull Math Biophys. 1969 Dec;31(4):727–60. DOI:10.1007/BF02477784
  • 26. Kettesy B, Vardai J, Berta A, Modis L, Kemeny-Beke A. A survey of corneal changes caused by daily wear silicone hydrogel contact lenses. J Innov Opt Health Sci. 2015 Nov 27;08(06):1550044. DOI:10.1142/S1793545815500443
There are 26 citations in total.

Details

Primary Language English
Subjects Ophthalmology
Journal Section Research Articles
Authors

Mübeccel Bulut 0000-0003-1311-2282

Ayşe Sevgi Karadağ 0000-0002-7662-6531

Early Pub Date March 26, 2025
Publication Date April 10, 2025
Submission Date December 25, 2023
Acceptance Date December 16, 2024
Published in Issue Year 2025Volume: 16 Issue: 2

Cite

EndNote Bulut M, Karadağ AS (April 1, 2025) INVESTIGATION OF CORNEAL CHANGES IN CONTACT LENS USERS. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 16 2 233–239.
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