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Year 2025, Volume: 16 Issue: Erken Çevrimiçi Yayınlar

Abstract

References

  • 1) Keleş H. Tıpta yapay zeka uygulamaları. Kırıkkale Üniversitesi Tıp Fakültesi, İç Hastalıkları A.D., Yahşihan, KIRIKKALE, TÜRKİYE.
  • 2) Dave T, Athaluri SA, Singh S. ChatGPT in medicine: An overview of its applications, advantages, limitations, future prospects, and ethical considerations. Front Artif Intell. 2023;6:1169595. Published 2023 May 4. doi:10.3389/frai.2023.1169595
  • 3) ChatGPT-4 generates more accurate and complete responses to common patient questions about anterior cruciate ligament reconstruction than Google’s search engine.
  • 4) Goktas P, Grzybowski A. Assessing the impact of ChatGPT in dermatology: A comprehensive rapid review. J Clin Med. 2024;13(19):5909. Published 2024 Oct 3. doi:10.3390/jcm13195909
  • 5) Antaki F, Touma S, Milad D, El-Khoury J, Duval R. Evaluating the performance of ChatGPT in ophthalmology: An analysis of its successes and shortcomings. Ophthalmol Sci. 2023;3(4):100324. Published 2023 May 5. doi:10.1016/j.xops.2023.100324
  • 6) Rajput I, Anjankar VP. Side effects of treating acne vulgaris with isotretinoin: A systematic review. Cureus. 2024;16(3)Published 2024 Mar 11. doi:10.7759/cureus.55946
  • 7) Rocha M, Barnes F, Calderón J, et al. Acne treatment challenges - Recommendations of Latin American expert consensus. An Bras Dermatol. 2024;99(3):414-424. doi:10.1016/j.abd.2023.09.001
  • 8) Ataseven A, Ugur Bilgin A. Effects of isotretinoin on the platelet counts and the mean platelet volume in patients with acne vulgaris. ScientificWorldJournal. 2014;2014:156464. doi:10.1155/2014/156464
  • 9) Mika AP, Martin JR, Engstrom SM, Polkowski GG, Wilson JM. Assessing ChatGPT responses to common patient questions regarding total hip arthroplasty. J Bone Joint Surg Am. 2023;105(19):1519-1526. doi:10.2106/JBJS.23.00209
  • 10) Lamberg, O., Strome, A., Jones, F., Mleczek, J., Jarocki, A., Troost, J. P., & Helfrich, Y. (2023). Ocular side effects of systemic isotretinoin - a systematic review and summary of case reports. The Journal of dermatological treatment, 34(1), 2213364. https://doi.org/10.1080/09546634.2023.2213364
  • 11) Dahmen J, Kayaalp ME, Ollivier M, et al. Artificial intelligence bot ChatGPT in medical research: The potential game changer as a double-edged sword. Knee Surg Sports Traumatol Arthrosc. 2023;31(4):1187-1189. doi:10.1007/s00167-023-07355-6
  • 12) Lakdawala N, Channa L, Gronbeck C, et al. Assessing the accuracy and comprehensiveness of ChatGPT in offering clinical guidance for atopic dermatitis and acne vulgaris. JMIR Dermatol. 2023;6. Published 2023 Nov 14. doi:10.2196/50409
  • 13) Fraunfelder FT, Fraunfelder FW, Edwards R. Ocular side effects possibly associated with isotretinoin usage. Am J Ophthalmol. 2001;132(3):299-305. doi:10.1016/s0002-9394(01)01024-8
  • 14) Gündüz ÖU, Baş ADZ. Kontakt lens kullanımı ile ilişkili kuru göz. MN Oftalmoloji. 2016;23(Suppl 1):83-90.
  • 15) Nair S, Kaur M, Sharma N, Titiyal JS. Refractive surgery and dry eye - An update. Indian J Ophthalmol. 2023;71(4):1105-1114. doi:10.4103/IJO.IJO_3406_22
  • 16) Tan, S., Xin, X., & Wu, D. (2024). ChatGPT in medicine: prospects and challenges: a review article. International journal of surgery (London, England), 110(6), 3701–3706. https://doi.org/10.1097/JS9.0000000000001312
  • 17) Campbell, D. J., Estephan, L. E., Mastrolonardo, E. V., Amin, D. R., Huntley, C. T., & Boon, M. S. (2023). Evaluating ChatGPT responses on obstructive sleep apnea for patient education. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 19(12), 1989–1995. https://doi.org/10.5664/jcsm.10728

Artificial Intelligence and Systemic Isotretinoin: Patient Education on Ophthalmological Side Effects

Year 2025, Volume: 16 Issue: Erken Çevrimiçi Yayınlar

Abstract

Background/Purpose: Isotretinoin is frequently utilized in the treatment of skin disorders such as acne vulgaris and rosacea, with its associated side effects occurring relatively often. The most prevalent ophthalmological adverse effects include conjunctivitis, hordeolum, chalazion, blepharitis, and xerophthalmia. In light of the growing integration of artificial intelligence within healthcare, this study aims to evaluate the capability of ChatGPT to enhance patient education regarding these conditions.

Materials and Methods: A questionnaire consisting of fifteen frequently asked questions concerning the ocular side effects of systemic isotretinoin was developed. Eight questions, selected by a dermatologist and a ophthalmologist, were posed to ChatGPT version 4.0. The responses were assessed using a four-point rating scale. Answers were independently categorized as "excellent," "satisfactory with minimal explanation required," "satisfactory with moderate explanation required," or "unsatisfactory."

Results: ChatGPT provided accurate and informative responses to all eight questions presented. Six responses were rated as "excellent," while two were categorized as "satisfactory with minimal explanation required." Inter-rater reliability was assessed using Cohen's kappa analysis, resulting in a kappa value of 0.413 (95% confidence interval, 0.007 to 0.825).

Conclusion: ChatGPT exhibited a significant capacity to effectively address patient inquiries related to the ophthalmological side effects of systemic isotretinoin. Following a review by dermatologists and ophthalmologists, it may serve as a valuable complementary tool for patient education.

Thanks

OP.DR MURAT ERDAĞA MAKALEMİZE YAPTIGI KATKILAR ICIN TESEKKUR EDERIZ

References

  • 1) Keleş H. Tıpta yapay zeka uygulamaları. Kırıkkale Üniversitesi Tıp Fakültesi, İç Hastalıkları A.D., Yahşihan, KIRIKKALE, TÜRKİYE.
  • 2) Dave T, Athaluri SA, Singh S. ChatGPT in medicine: An overview of its applications, advantages, limitations, future prospects, and ethical considerations. Front Artif Intell. 2023;6:1169595. Published 2023 May 4. doi:10.3389/frai.2023.1169595
  • 3) ChatGPT-4 generates more accurate and complete responses to common patient questions about anterior cruciate ligament reconstruction than Google’s search engine.
  • 4) Goktas P, Grzybowski A. Assessing the impact of ChatGPT in dermatology: A comprehensive rapid review. J Clin Med. 2024;13(19):5909. Published 2024 Oct 3. doi:10.3390/jcm13195909
  • 5) Antaki F, Touma S, Milad D, El-Khoury J, Duval R. Evaluating the performance of ChatGPT in ophthalmology: An analysis of its successes and shortcomings. Ophthalmol Sci. 2023;3(4):100324. Published 2023 May 5. doi:10.1016/j.xops.2023.100324
  • 6) Rajput I, Anjankar VP. Side effects of treating acne vulgaris with isotretinoin: A systematic review. Cureus. 2024;16(3)Published 2024 Mar 11. doi:10.7759/cureus.55946
  • 7) Rocha M, Barnes F, Calderón J, et al. Acne treatment challenges - Recommendations of Latin American expert consensus. An Bras Dermatol. 2024;99(3):414-424. doi:10.1016/j.abd.2023.09.001
  • 8) Ataseven A, Ugur Bilgin A. Effects of isotretinoin on the platelet counts and the mean platelet volume in patients with acne vulgaris. ScientificWorldJournal. 2014;2014:156464. doi:10.1155/2014/156464
  • 9) Mika AP, Martin JR, Engstrom SM, Polkowski GG, Wilson JM. Assessing ChatGPT responses to common patient questions regarding total hip arthroplasty. J Bone Joint Surg Am. 2023;105(19):1519-1526. doi:10.2106/JBJS.23.00209
  • 10) Lamberg, O., Strome, A., Jones, F., Mleczek, J., Jarocki, A., Troost, J. P., & Helfrich, Y. (2023). Ocular side effects of systemic isotretinoin - a systematic review and summary of case reports. The Journal of dermatological treatment, 34(1), 2213364. https://doi.org/10.1080/09546634.2023.2213364
  • 11) Dahmen J, Kayaalp ME, Ollivier M, et al. Artificial intelligence bot ChatGPT in medical research: The potential game changer as a double-edged sword. Knee Surg Sports Traumatol Arthrosc. 2023;31(4):1187-1189. doi:10.1007/s00167-023-07355-6
  • 12) Lakdawala N, Channa L, Gronbeck C, et al. Assessing the accuracy and comprehensiveness of ChatGPT in offering clinical guidance for atopic dermatitis and acne vulgaris. JMIR Dermatol. 2023;6. Published 2023 Nov 14. doi:10.2196/50409
  • 13) Fraunfelder FT, Fraunfelder FW, Edwards R. Ocular side effects possibly associated with isotretinoin usage. Am J Ophthalmol. 2001;132(3):299-305. doi:10.1016/s0002-9394(01)01024-8
  • 14) Gündüz ÖU, Baş ADZ. Kontakt lens kullanımı ile ilişkili kuru göz. MN Oftalmoloji. 2016;23(Suppl 1):83-90.
  • 15) Nair S, Kaur M, Sharma N, Titiyal JS. Refractive surgery and dry eye - An update. Indian J Ophthalmol. 2023;71(4):1105-1114. doi:10.4103/IJO.IJO_3406_22
  • 16) Tan, S., Xin, X., & Wu, D. (2024). ChatGPT in medicine: prospects and challenges: a review article. International journal of surgery (London, England), 110(6), 3701–3706. https://doi.org/10.1097/JS9.0000000000001312
  • 17) Campbell, D. J., Estephan, L. E., Mastrolonardo, E. V., Amin, D. R., Huntley, C. T., & Boon, M. S. (2023). Evaluating ChatGPT responses on obstructive sleep apnea for patient education. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 19(12), 1989–1995. https://doi.org/10.5664/jcsm.10728
There are 17 citations in total.

Details

Primary Language English
Subjects Dermatology
Journal Section Research Articles
Authors

Seçil Yigen İritaş 0000-0003-4462-6526

İlter İritaş 0000-0003-1789-4787

Early Pub Date June 18, 2025
Publication Date
Submission Date November 3, 2024
Acceptance Date April 25, 2025
Published in Issue Year 2025Volume: 16 Issue: Erken Çevrimiçi Yayınlar

Cite

EndNote Yigen İritaş S, İritaş İ (June 1, 2025) Artificial Intelligence and Systemic Isotretinoin: Patient Education on Ophthalmological Side Effects. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 16 Erken Çevrimiçi Yayınlar