The Effects of Individual Exercise Program on Siblings with Spinal Muscular Atrophy Type 3: A Case Report
Abstract
Spinal Muscular Atrophy (SMA) type 3 is an autosomal recessive disease that occurs as a result of the degeneration of the motor neurons of the spinal cord and causes severe functional impairment in patients. This case report aims to examine the effects of individual exercise programs on functional performance applied to two siblings with SMA type 3. SMA type-3 siblings were examined in the case report. The siblings were included in an 8-week individually planned exercise program. Before and after the exercise program, the motor performance, trunk impairment, spatiotemporal parameters of gait, balance and activities of daily living were evaluated with Motor Functional Measurement, Trunk Impairment Scale, GAITRite electronic walkway, Bertec Balance Check ScreenerTM force platform system and Functional Impairment Measurement, respectively. The individually planned exercise program had positive effects on trunk impairment, gait, balance and activities of daily living in siblings with SMA type 3. An individual exercise program that is planned by the functional status of the patient and includes different exercise types is extremely important to increase the functional independence of SMA Type-3 patients during the rehabilitation process.
Keywords
References
- 1. Lunn MR, Wang CH. Spinal muscular atrophy. Lancet 2008; 371(9630): 2120-33.
- 2. Bartels B, Montes J, van der Pol WL, de Groot JF. Skeletal muscle training for spinal muscular atrophy type 3. Cochrane Database of Systematic Reviews 2016; 2016(3).
- 3. Mercuri E, Bertini E, Iannaccone ST. Childhood spinal muscular atrophy: controversies and challenges. Lancet Neurol 2012; 11(5): 443-52.
- 4. Bartels B, Montes J, van der Pol WL, de Groot JF. Physical exercise training for type 3 spinal muscular atrophy. Cochrane Database of Systematic Reviews 2019(3).
- 5. Bérard C, Payan C, Hodgkinson I, Fermanian J, Group MCS. A motor function measure scale for neuromuscular diseases. Construction and validation study. Neuromuscul Disord 2005; 15(7): 463-70.
- 6. O’Hagen JM, Glanzman AM, McDermott MP, Ryan PA, Flickinger J, Quigley J, et al. An expanded version of the Hammersmith Functional Motor Scale for SMA II and III patients. Neuromuscul Disord. 2007;17(9-10):693-7.
- 7. Verheyden G, Nieuwboer A, Mertin J, Preger R, Kiekens C, De Weerdt W. The Trunk Impairment Scale: a new tool to measure motor impairment of the trunk after stroke. Clin Rehabil 2004; 18(3): 326-34.
- 8. Webster KE, Wittwer JE, Feller JA. Validity of the GAITRite® walkway system for the measurement of averaged and individual step parameters of gait. Gait Posture 2005; 22(4): 317-21.
- 9. Özkal Ö, Kara M, Topuz S, Kaymak B, Bakı A, Özçakar L. Assessment of core and lower limb muscles for static/dynamic balance in the older people: An ultrasonographic study. Age Ageing 2019; 48(6): 881-7.
- 10. Ottenbacher KJ, Hsu Y, Granger CV, Fiedler RC. The reliability of the functional independence measure: a quantitative review. Arch Phys Med Rehabil 1996; 77(12): 1226-32.
- 11. Madsen KL, Hansen RS, Preisler N, Thøgersen F, Berthelsen MP, Vissing J. Training improves oxidative capacity, but not function, in spinal muscular atrophy type III. Muscle Nerve 2015; 52(2): 240-4.
- 12. Montes J, Garber CE, Kramer SS, Montgomery MJ, Dunaway S, Kamil-Rosenberg S, et al. A randomized, controlled clinical trial of exercise in patients with spinal muscular atrophy: methods and baseline characteristics. J Neuromuscul Dis 2014; 1(2): 151-61.
Abstract
References
- 1. Lunn MR, Wang CH. Spinal muscular atrophy. Lancet 2008; 371(9630): 2120-33.
- 2. Bartels B, Montes J, van der Pol WL, de Groot JF. Skeletal muscle training for spinal muscular atrophy type 3. Cochrane Database of Systematic Reviews 2016; 2016(3).
- 3. Mercuri E, Bertini E, Iannaccone ST. Childhood spinal muscular atrophy: controversies and challenges. Lancet Neurol 2012; 11(5): 443-52.
- 4. Bartels B, Montes J, van der Pol WL, de Groot JF. Physical exercise training for type 3 spinal muscular atrophy. Cochrane Database of Systematic Reviews 2019(3).
- 5. Bérard C, Payan C, Hodgkinson I, Fermanian J, Group MCS. A motor function measure scale for neuromuscular diseases. Construction and validation study. Neuromuscul Disord 2005; 15(7): 463-70.
- 6. O’Hagen JM, Glanzman AM, McDermott MP, Ryan PA, Flickinger J, Quigley J, et al. An expanded version of the Hammersmith Functional Motor Scale for SMA II and III patients. Neuromuscul Disord. 2007;17(9-10):693-7.
- 7. Verheyden G, Nieuwboer A, Mertin J, Preger R, Kiekens C, De Weerdt W. The Trunk Impairment Scale: a new tool to measure motor impairment of the trunk after stroke. Clin Rehabil 2004; 18(3): 326-34.
- 8. Webster KE, Wittwer JE, Feller JA. Validity of the GAITRite® walkway system for the measurement of averaged and individual step parameters of gait. Gait Posture 2005; 22(4): 317-21.
- 9. Özkal Ö, Kara M, Topuz S, Kaymak B, Bakı A, Özçakar L. Assessment of core and lower limb muscles for static/dynamic balance in the older people: An ultrasonographic study. Age Ageing 2019; 48(6): 881-7.
- 10. Ottenbacher KJ, Hsu Y, Granger CV, Fiedler RC. The reliability of the functional independence measure: a quantitative review. Arch Phys Med Rehabil 1996; 77(12): 1226-32.
- 11. Madsen KL, Hansen RS, Preisler N, Thøgersen F, Berthelsen MP, Vissing J. Training improves oxidative capacity, but not function, in spinal muscular atrophy type III. Muscle Nerve 2015; 52(2): 240-4.
- 12. Montes J, Garber CE, Kramer SS, Montgomery MJ, Dunaway S, Kamil-Rosenberg S, et al. A randomized, controlled clinical trial of exercise in patients with spinal muscular atrophy: methods and baseline characteristics. J Neuromuscul Dis 2014; 1(2): 151-61.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Publication Date | May 31, 2022 |
| Submission Date | September 29, 2021 |
| Published in Issue | Year 2022 Volume: 6 Issue: 2 |
