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Astımlı kadın hastaların hastaneye yatışlarını etkileyen faktörler

Year 2019, Volume: 3 Issue: 9, 698 - 701, 01.09.2019

Gökhan Perincek Sema Avcı

https://doi.org/10.28982/josam.616836

Abstract

Amaç: Astım en yaygın kronik solunum hastalıklarından biridir ve mortaliteye yol açan önemli bir halk sağlığı problemidir. Bu çalışmanın amacı astımlı kadın hastaların hastaneye yatış oranlarını değerlendirmektir. 

Yöntemler: Bu kesitsel çalışma bir üniversite hastanesi etik kurulundan onay alınarak Eylül 2018 ve Ocak 2019 tarihleri arasında yapıldı. Çalışmaya 183 kadın hasta dahil edildi (alevlenme olan 56 hasta Grup 1 ve stabil astım olan 127 hasta Grup 2 olarak adlandırıldı). Demografik özellikler, akciğer fonksiyon testleri, hastaneye başvuru sayıları, hastaneye yatış oranları ve laboratuvar bulguları değerlendirildi. Tüm istatistik hesaplamaları SPPS 23.0 Windows ile yapıldı.

Bulgular: Grup 1’deki hastaların ortalama yaşı daha büyüktü (P=0,003). Grup 1’de hastaneye yatış ve acil servise başvuru sayıları önemli derecede yüksekti (P<0,001). Grup 1’deki hastalar daha düşük oksijen satürasyonu, FEV1, FVC, FEV1/FVC’ye ve daha yüksek solunum sayısı ve kalp atım sayısına sahipti. Bu grupta, hastalar daha yüksek kan glukozu, beyaz küre, nötrofil sayısına ve daha düşük fosfor, yüksek dansiteli lipoprotein ve kalsiyum düzeylerine sahipti. Artmış eozinofil sayısı ve azalmış bazofil sayısı acil servis başvuru oranları ile ilişkili idi (P=0,043).

Sonuç: Sonuç olarak, astım alevlenme ile hastaneye başvuran kadınlar daha yaşlıydı ve hastaneye yatış oranları daha fazlaydı. Yüksek eozinofil kan seviyeleri tekrarlayan hastaneye başvurular ile ilişkilidir.

Keywords

Astım Hastaneye yatış Kadın

References

  • 1. Tarraf H, Aydin O, Mungan D, Albader M, Mahboub B, Doble A, et al. Prevalence of asthma among the adult general population of five Middle Eastern countries:results of the SNAPSHOT program. BMC Pulm Med. 2018;18:68.
  • 2. Gonzalez-Barcala FJ, Aboal J, Valdes L, Carreira JM, Alvarez-Dobaño JM, Puga A, et al. Trends in adult asthma hospitalization:gender-age effect. Multidiscip Respir Med. 2011;6:82-6.
  • 3. Zein JG, Erzurum SC. Asthma is different in women. Curr Allergy Asthma Rep. 2015;15:28.
  • 4. Global Strategy for Asthma Management and Prevention. 2018 Update.
  • 5. Kang HR, Song HJ, Nam JH, Hong SH, Yang SY, Ju SE, et al. Risk factors of asthma exacerbation based on asthma severity: a nationwide population-based observational study in South Korea. BMJ Open. 2018;8.
  • 6. Sekiya K, Taniguchi M, Fukutomi Y, Watai K, Minami T, Hayashi H, et al. Age-specific characteristics of inpatients with severe asthma exacerbation. Allergol Int. 2013;62:331-6.
  • 7. Chung HY, Kim DH, Lee EK, Chung KW, Chung S, Lee B, et al. Redefining chronic inflammation in aging and age-related diseases:proposal of the senoinflammation concept. Aging Dis. 2019;10:367-82.
  • 8. Pola-Bibian B, Dominguez-Ortega J, Vilà-Nadal G, Entrala A, González-Cavero L, Barranco P, et al. Asthma exacerbations in a tertiary hospital:clinical features, triggers, and risk factors for hospitalization. J Investig Allergol Clin Immunol. 2017;27:238-45.
  • 9. Lutfi MF, Sukkar MY. The hyperglycemic effect of bronchial asthma. Sudan Med J. 2011;47:69-74.
  • 10. Navratil M, Jureković II, Topalušić I, Švigir A, Andrijašević N, Rubić F. Association of asthma symptoms and exacerbation with inflammatory biomarkers. Clin Pediatr. 2017;2:122.
  • 11. Hatipoğlu H, Erkal S, Türkmen S, Engerek N, Kurt K, Şiraneci R. Enfeksiyon hastalıklarının tanısında laboratuvar bulguları. JOPP Derg. 2011;3:5-11.
  • 12. Yıldırım ÖT, Akşit E, Aydın F, Aydın AH, Dağtekin E. Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio can be used as biomarkers for non-dipper blood pressure. J Surg Med. 2019;3(1):4-7.
  • 13. Fergeson JE, Patel SS, Lockey RF. Acute asthma, prognosis, and treatment. J Allergy Clin Immunol. 2017;139:438-47.
  • 14. Middleton E, Buffalo NY. Airway smooth muscle, asthma, and calcium ions. J Allergy Clin Immunol. 1984;73:643-50.
  • 15. Umalakshmi V, Bhargavi K. Serum creatine kinase, lactate dehydrogenase and lipid profile in patients with asthma. IOSR-JPBS. 2015;10:53-6.
  • 16. Heffler E, Terranova G, Chessari C, Frazzetto V, Crimi C, Fichera S, et al. Point-of-care blood eosinophil count in a severe asthma clinic setting. Ann Allergy Asthma Immunol. 2017;119:16-20.
  • 17. Nagasaki T, Sato K, Kume N, Oguma T, Sunadome H, Ito I, et al. The prevalence and disease burden of severe eosinophilic asthma in Japan. J Asthma. 2019.
  • 18. Bjerregaard A, Laing IA, Backer V, Fally M, Khoo SK, Chidlow G, et al. Clinical characteristics of eosinophilic asthma exacerbations. Respir. 2017;22:295–300.
  • 19. Siracusa MC, Kim BS, Spergel JM, Artis D. Basophils and allergic inflammation. J Allergy Clin Immunol. 2013;132:789-801.

Factors affecting the hospitalization of female patients with asthma

Year 2019, Volume: 3 Issue: 9, 698 - 701, 01.09.2019

Gökhan Perincek Sema Avcı

https://doi.org/10.28982/josam.616836

Abstract

Aim: Asthma is one of the most common chronic respiratory diseases and an important public health problem leading to mortality. The aim of this study was to evaluate the hospitalization rates of female patients with asthma.

Methods: This cross-sectional study was conducted with the approval of a university hospital ethics committee between September 2018 and January 2019. The study included a total of 183 females: 56 patients with exacerbation were included in Group 1 and 127 patients with stable asthma constituted Group 2. Demographic data, pulmonary function test results, number of hospital admissions, hospitalization rates and laboratory findings were evaluated. All statistical calculations were performed with SPSS 23.0 for Windows.

Results: The mean age, number of hospitalizations and admissions to the emergency room were significantly higher in Group 1 (P=0.003, P<0.001 and P<0.001, respectively). Patients in Group 1 had lower oxygen saturations, FEV1, FVC, FEV1/FVC values, higher respiratory and heart rates, blood glucose, lactate dehydrogenase, c-reactive protein, lactate, phosphorus, high-density lipoprotein, calcium levels, white blood cell and neutrophil counts. Increased eosinophil count and decreased basophil count were associated with increased emergency room admission rates (P=0.043).

Conclusion: Women admitted to the hospital with asthma exacerbation were older and had an increased number of hospitalization rates. Higher eosinophil blood levels were associated with recurrent hospital admissions.

Keywords

Asthma Hospitalization Female

References

  • 1. Tarraf H, Aydin O, Mungan D, Albader M, Mahboub B, Doble A, et al. Prevalence of asthma among the adult general population of five Middle Eastern countries:results of the SNAPSHOT program. BMC Pulm Med. 2018;18:68.
  • 2. Gonzalez-Barcala FJ, Aboal J, Valdes L, Carreira JM, Alvarez-Dobaño JM, Puga A, et al. Trends in adult asthma hospitalization:gender-age effect. Multidiscip Respir Med. 2011;6:82-6.
  • 3. Zein JG, Erzurum SC. Asthma is different in women. Curr Allergy Asthma Rep. 2015;15:28.
  • 4. Global Strategy for Asthma Management and Prevention. 2018 Update.
  • 5. Kang HR, Song HJ, Nam JH, Hong SH, Yang SY, Ju SE, et al. Risk factors of asthma exacerbation based on asthma severity: a nationwide population-based observational study in South Korea. BMJ Open. 2018;8.
  • 6. Sekiya K, Taniguchi M, Fukutomi Y, Watai K, Minami T, Hayashi H, et al. Age-specific characteristics of inpatients with severe asthma exacerbation. Allergol Int. 2013;62:331-6.
  • 7. Chung HY, Kim DH, Lee EK, Chung KW, Chung S, Lee B, et al. Redefining chronic inflammation in aging and age-related diseases:proposal of the senoinflammation concept. Aging Dis. 2019;10:367-82.
  • 8. Pola-Bibian B, Dominguez-Ortega J, Vilà-Nadal G, Entrala A, González-Cavero L, Barranco P, et al. Asthma exacerbations in a tertiary hospital:clinical features, triggers, and risk factors for hospitalization. J Investig Allergol Clin Immunol. 2017;27:238-45.
  • 9. Lutfi MF, Sukkar MY. The hyperglycemic effect of bronchial asthma. Sudan Med J. 2011;47:69-74.
  • 10. Navratil M, Jureković II, Topalušić I, Švigir A, Andrijašević N, Rubić F. Association of asthma symptoms and exacerbation with inflammatory biomarkers. Clin Pediatr. 2017;2:122.
  • 11. Hatipoğlu H, Erkal S, Türkmen S, Engerek N, Kurt K, Şiraneci R. Enfeksiyon hastalıklarının tanısında laboratuvar bulguları. JOPP Derg. 2011;3:5-11.
  • 12. Yıldırım ÖT, Akşit E, Aydın F, Aydın AH, Dağtekin E. Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio can be used as biomarkers for non-dipper blood pressure. J Surg Med. 2019;3(1):4-7.
  • 13. Fergeson JE, Patel SS, Lockey RF. Acute asthma, prognosis, and treatment. J Allergy Clin Immunol. 2017;139:438-47.
  • 14. Middleton E, Buffalo NY. Airway smooth muscle, asthma, and calcium ions. J Allergy Clin Immunol. 1984;73:643-50.
  • 15. Umalakshmi V, Bhargavi K. Serum creatine kinase, lactate dehydrogenase and lipid profile in patients with asthma. IOSR-JPBS. 2015;10:53-6.
  • 16. Heffler E, Terranova G, Chessari C, Frazzetto V, Crimi C, Fichera S, et al. Point-of-care blood eosinophil count in a severe asthma clinic setting. Ann Allergy Asthma Immunol. 2017;119:16-20.
  • 17. Nagasaki T, Sato K, Kume N, Oguma T, Sunadome H, Ito I, et al. The prevalence and disease burden of severe eosinophilic asthma in Japan. J Asthma. 2019.
  • 18. Bjerregaard A, Laing IA, Backer V, Fally M, Khoo SK, Chidlow G, et al. Clinical characteristics of eosinophilic asthma exacerbations. Respir. 2017;22:295–300.
  • 19. Siracusa MC, Kim BS, Spergel JM, Artis D. Basophils and allergic inflammation. J Allergy Clin Immunol. 2013;132:789-801.
There are 19 citations in total.

Details

Primary Language English
Subjects Respiratory Diseases
Journal Section Research article
Authors

Gökhan Perincek 0000-0003-2400-6346

Sema Avcı 0000-0002-0992-4192

Publication Date September 1, 2019
Published in Issue Year 2019 Volume: 3 Issue: 9

Cite

APA Perincek, G., & Avcı, S. (2019). Factors affecting the hospitalization of female patients with asthma. Journal of Surgery and Medicine, 3(9), 698-701. https://doi.org/10.28982/josam.616836
AMA Perincek G, Avcı S. Factors affecting the hospitalization of female patients with asthma. J Surg Med. September 2019;3(9):698-701. doi:10.28982/josam.616836
Chicago Perincek, Gökhan, and Sema Avcı. “Factors Affecting the Hospitalization of Female Patients With Asthma”. Journal of Surgery and Medicine 3, no. 9 (September 2019): 698-701. https://doi.org/10.28982/josam.616836.
EndNote Perincek G, Avcı S (September 1, 2019) Factors affecting the hospitalization of female patients with asthma. Journal of Surgery and Medicine 3 9 698–701.
IEEE G. Perincek and S. Avcı, “Factors affecting the hospitalization of female patients with asthma”, J Surg Med, vol. 3, no. 9, pp. 698–701, 2019, doi: 10.28982/josam.616836.
ISNAD Perincek, Gökhan - Avcı, Sema. “Factors Affecting the Hospitalization of Female Patients With Asthma”. Journal of Surgery and Medicine 3/9 (September 2019), 698-701. https://doi.org/10.28982/josam.616836.
JAMA Perincek G, Avcı S. Factors affecting the hospitalization of female patients with asthma. J Surg Med. 2019;3:698–701.
MLA Perincek, Gökhan and Sema Avcı. “Factors Affecting the Hospitalization of Female Patients With Asthma”. Journal of Surgery and Medicine, vol. 3, no. 9, 2019, pp. 698-01, doi:10.28982/josam.616836.
Vancouver Perincek G, Avcı S. Factors affecting the hospitalization of female patients with asthma. J Surg Med. 2019;3(9):698-701.
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