Case Report
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Year 2022, Volume: 6 Issue: 3, 405 - 407, 01.03.2022

Filiz Banu Çetinkaya Ethemoğlu İrem Gümüş Özcan

https://doi.org/10.28982/josam.907301

Abstract

References

  • 1. Brown RA. Hepatic and renal damage with paractamol overdosage. J Clin Pathol. 1968;21(6):793.
  • 2. Bateman DN. Changing the management of paracetamol poisoning. Clin Ther. 2015;37(9):2135-41.
  • 3. Roberts LJ, Morrow JD. Analgesic-antipyretic and anti inflammatory agents and drugs employed in the treatment of gout. In: Hardman JG, Limbird LE, Gilman AG, editors. Goodman and Gilman's the pharmacological basis of therapeutics. 10th ed. New York: McGraw-Hill; 2001. p. 687-732.
  • 4. Werler MM, Mitchell AA, Hernandez-Diaz S, Honein MA. Use of over-the-counter medications during pregnancy. Am J Obstet Gynecol.2005;193(3 Pt 1):771–7.
  • 5. McClure CK, Katz KD, Patrick TE, Kelsey SF, Weiss HB. The epidemiology of acute poisonings in women of reproductive age and during pregnancy, California, 2000–2004. Matern Child Health J. 2011;15(7):964–73.
  • 6. Hendrickson RG, Bizovi KE. Acetaminophene. In Flomenbaum NE, Goldfrank LR, Hoffman RS, Howland MA, Lewin NA, Nelson NA, Editors. Goldfrank’s Toxicologic Emergencies. 8th ed. New York: McGraw-Hill; 2006. p.333-43.
  • 7. Rumack BH, Matthew H. Acetaminophen poisoning and toxicity. Pediatrics. 1975;55(6):871-6.
  • 8. Boutis K, Shannon M. Nephrotoxicity after acute severe acetaminophen poisoning in adolescents. J Toxicol Clin Toxicol. 2001;39(5):441-5.
  • 9. McElhatton PR, Sullivan FM, Volans GN, Fitzpatrick R. Paracetamol poisoning in pregnancy: an analysis of the outcomes of cases referred to the Teratology Information Service of the National Poisons Information Service. Hum Exp Toxicol. 1990; 9(3):147–53.
  • 10. Oliver LH, Lewis SN. Acetaminophen. In Judith E.Tintinalli,MD,MS, Editor. Emergency Medicine.7th ed. New York: McGraw-Hill;2010.p.1246-52.
  • 11. Beers MH, Porter RS, Jones TV, Kaplan JL, Berkwits M (ed.). The Merck manuel tanı ve tedavi el kitabı. 18th ed.(çev.Z. Solakoğlu)İstanbul:Nobel kitapevi. 2006.p.2658-9.
  • 12. Stokes IM. Paracetamol overdose in the second trimester of pregnancy. Case report. Br J Obstet Gynaecol. 1984;91(3):286–8.
  • 13. Haibach H, Akhter JE, Muscato MS, Cary PL, Hoffmann MF. Acetaminophen overdose with fetal demise. Am J Clin Pathol. 1984;82(2):240–2.
  • 14. Stephen L, Thornton & Alicia B, Minns. Unintentional Chronic Acetaminophen Poisoning During Pregnancy Resulting in Liver Transplantation J. Med. Toxicol. 2012;8:176–8.
  • 15. Duman M. K., Kalyoncu İ. Drug Choice in Pregnancy and Teratogenicity Information Services. Turkiye Klinikleri J Surg Med Sci. 2006;2(46):63-8.
  • 16. Singer AJ, Carracio TR, Mofenson HC. The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction. Ann Emerg Med. 1995;26(1):49-53.
  • 17. Bessems JG, Vermeulen NP. Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches. Crit Rev Toxicol. 2001;31(1):55-138.
  • 18. Lancaster EM, Hiatt JR, Zarrinpar A. Acetaminophen hepatotoxicity: an updated review. Arch Toxicol. 2015;89(2):193-9.
  • 19. Ferner RE, Dear JW, Bateman DN. Management of paracetamol poisoning. BMJ. 2011;342:d2218.
  • 20. Bateman DN, Dear JW, Thanacoody HK, Thomas SH, Eddleston M, Sandilands EA, et al. Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. Lancet. 2014;383(9918):697-704.
  • 21. Kerr F, Dawson A, Whyte IM, Buckley N, Mur- ray L, Graudins A, et al. The Australasian clinical toxicology investigators collaboration ran- domized trial of different loading infusion rates of N-acetylcysteine. Ann Emerg Med. 2005;45(4):402-8.

Approach to paracetamol intoxication in intensive care: 2 pregnant cases

Year 2022, Volume: 6 Issue: 3, 405 - 407, 01.03.2022

Filiz Banu Çetinkaya Ethemoğlu İrem Gümüş Özcan

https://doi.org/10.28982/josam.907301

Abstract

Acetaminophen (paracetamol) is a commonly used drug during pregnancy and is considered safe. However, it is among the most frequent agents of which overdoses are reported during pregnancy. The most important result of overdose use is hepatotoxicity, which can cause death. We herein present our approach to two pregnant cases we followed up in the intensive care unit due to acetaminophen intoxication.

Keywords

Acetaminophen Pregnancy Intoxication Unit care

References

  • 1. Brown RA. Hepatic and renal damage with paractamol overdosage. J Clin Pathol. 1968;21(6):793.
  • 2. Bateman DN. Changing the management of paracetamol poisoning. Clin Ther. 2015;37(9):2135-41.
  • 3. Roberts LJ, Morrow JD. Analgesic-antipyretic and anti inflammatory agents and drugs employed in the treatment of gout. In: Hardman JG, Limbird LE, Gilman AG, editors. Goodman and Gilman's the pharmacological basis of therapeutics. 10th ed. New York: McGraw-Hill; 2001. p. 687-732.
  • 4. Werler MM, Mitchell AA, Hernandez-Diaz S, Honein MA. Use of over-the-counter medications during pregnancy. Am J Obstet Gynecol.2005;193(3 Pt 1):771–7.
  • 5. McClure CK, Katz KD, Patrick TE, Kelsey SF, Weiss HB. The epidemiology of acute poisonings in women of reproductive age and during pregnancy, California, 2000–2004. Matern Child Health J. 2011;15(7):964–73.
  • 6. Hendrickson RG, Bizovi KE. Acetaminophene. In Flomenbaum NE, Goldfrank LR, Hoffman RS, Howland MA, Lewin NA, Nelson NA, Editors. Goldfrank’s Toxicologic Emergencies. 8th ed. New York: McGraw-Hill; 2006. p.333-43.
  • 7. Rumack BH, Matthew H. Acetaminophen poisoning and toxicity. Pediatrics. 1975;55(6):871-6.
  • 8. Boutis K, Shannon M. Nephrotoxicity after acute severe acetaminophen poisoning in adolescents. J Toxicol Clin Toxicol. 2001;39(5):441-5.
  • 9. McElhatton PR, Sullivan FM, Volans GN, Fitzpatrick R. Paracetamol poisoning in pregnancy: an analysis of the outcomes of cases referred to the Teratology Information Service of the National Poisons Information Service. Hum Exp Toxicol. 1990; 9(3):147–53.
  • 10. Oliver LH, Lewis SN. Acetaminophen. In Judith E.Tintinalli,MD,MS, Editor. Emergency Medicine.7th ed. New York: McGraw-Hill;2010.p.1246-52.
  • 11. Beers MH, Porter RS, Jones TV, Kaplan JL, Berkwits M (ed.). The Merck manuel tanı ve tedavi el kitabı. 18th ed.(çev.Z. Solakoğlu)İstanbul:Nobel kitapevi. 2006.p.2658-9.
  • 12. Stokes IM. Paracetamol overdose in the second trimester of pregnancy. Case report. Br J Obstet Gynaecol. 1984;91(3):286–8.
  • 13. Haibach H, Akhter JE, Muscato MS, Cary PL, Hoffmann MF. Acetaminophen overdose with fetal demise. Am J Clin Pathol. 1984;82(2):240–2.
  • 14. Stephen L, Thornton & Alicia B, Minns. Unintentional Chronic Acetaminophen Poisoning During Pregnancy Resulting in Liver Transplantation J. Med. Toxicol. 2012;8:176–8.
  • 15. Duman M. K., Kalyoncu İ. Drug Choice in Pregnancy and Teratogenicity Information Services. Turkiye Klinikleri J Surg Med Sci. 2006;2(46):63-8.
  • 16. Singer AJ, Carracio TR, Mofenson HC. The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction. Ann Emerg Med. 1995;26(1):49-53.
  • 17. Bessems JG, Vermeulen NP. Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches. Crit Rev Toxicol. 2001;31(1):55-138.
  • 18. Lancaster EM, Hiatt JR, Zarrinpar A. Acetaminophen hepatotoxicity: an updated review. Arch Toxicol. 2015;89(2):193-9.
  • 19. Ferner RE, Dear JW, Bateman DN. Management of paracetamol poisoning. BMJ. 2011;342:d2218.
  • 20. Bateman DN, Dear JW, Thanacoody HK, Thomas SH, Eddleston M, Sandilands EA, et al. Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. Lancet. 2014;383(9918):697-704.
  • 21. Kerr F, Dawson A, Whyte IM, Buckley N, Mur- ray L, Graudins A, et al. The Australasian clinical toxicology investigators collaboration ran- domized trial of different loading infusion rates of N-acetylcysteine. Ann Emerg Med. 2005;45(4):402-8.
There are 21 citations in total.

Details

Primary Language English
Subjects Intensive Care
Journal Section Case report
Authors

Filiz Banu Çetinkaya Ethemoğlu 0000-0002-9321-3309

İrem Gümüş Özcan 0000-0001-5260-7945

Publication Date March 1, 2022
Published in Issue Year 2022 Volume: 6 Issue: 3

Cite

APA Çetinkaya Ethemoğlu, F. B., & Gümüş Özcan, İ. (2022). Approach to paracetamol intoxication in intensive care: 2 pregnant cases. Journal of Surgery and Medicine, 6(3), 405-407. https://doi.org/10.28982/josam.907301
AMA Çetinkaya Ethemoğlu FB, Gümüş Özcan İ. Approach to paracetamol intoxication in intensive care: 2 pregnant cases. J Surg Med. March 2022;6(3):405-407. doi:10.28982/josam.907301
Chicago Çetinkaya Ethemoğlu, Filiz Banu, and İrem Gümüş Özcan. “Approach to Paracetamol Intoxication in Intensive Care: 2 Pregnant Cases”. Journal of Surgery and Medicine 6, no. 3 (March 2022): 405-7. https://doi.org/10.28982/josam.907301.
EndNote Çetinkaya Ethemoğlu FB, Gümüş Özcan İ (March 1, 2022) Approach to paracetamol intoxication in intensive care: 2 pregnant cases. Journal of Surgery and Medicine 6 3 405–407.
IEEE F. B. Çetinkaya Ethemoğlu and İ. Gümüş Özcan, “Approach to paracetamol intoxication in intensive care: 2 pregnant cases”, J Surg Med, vol. 6, no. 3, pp. 405–407, 2022, doi: 10.28982/josam.907301.
ISNAD Çetinkaya Ethemoğlu, Filiz Banu - Gümüş Özcan, İrem. “Approach to Paracetamol Intoxication in Intensive Care: 2 Pregnant Cases”. Journal of Surgery and Medicine 6/3 (March 2022), 405-407. https://doi.org/10.28982/josam.907301.
JAMA Çetinkaya Ethemoğlu FB, Gümüş Özcan İ. Approach to paracetamol intoxication in intensive care: 2 pregnant cases. J Surg Med. 2022;6:405–407.
MLA Çetinkaya Ethemoğlu, Filiz Banu and İrem Gümüş Özcan. “Approach to Paracetamol Intoxication in Intensive Care: 2 Pregnant Cases”. Journal of Surgery and Medicine, vol. 6, no. 3, 2022, pp. 405-7, doi:10.28982/josam.907301.
Vancouver Çetinkaya Ethemoğlu FB, Gümüş Özcan İ. Approach to paracetamol intoxication in intensive care: 2 pregnant cases. J Surg Med. 2022;6(3):405-7.
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