Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement

Buket Tuğan Yıldız; Deniz Tuncel; Nursel Yurttutan; Şerife Çöklü

doi:10.28982/josam.955602

Case Report

Year 2022, Volume: 6 Issue: 4, 540 - 542, 01.04.2022

Buket Tuğan Yıldız Deniz Tuncel Nursel Yurttutan Şerife Çöklü

https://doi.org/10.28982/josam.955602

Abstract

References

1. Brunner C, Lassmann H, Waehneldt TV, Matthieu JM, Linington C. Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2',3'-cyclic nucleotide 3'-phosphodiesterase in the CNS of adult rats. J Neurochem. 1989 Jan;52(1):296-304. doi: 10.1111/j.1471-4159.1989.tb10930.x. PMID: 2462020.
2. Reindl M, Di Pauli F, Rostásy K, Berger T. The spectrum of MOG autoantibody-associated demyelinating diseases. Nat Rev Neurol. 2013 Aug;9(8):455-61. doi: 10.1038/nrneurol.2013.118. Epub 2013 Jun 25. PMID: 23797245.
3. Tsuburaya RS, Miki N, Tanaka K, Kageyama T, Irahara K, Mukaida S, et al. Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a Japanese boy with recurrent optic neuritis. Brain Dev. 2015 Jan;37(1):145-8. doi: 10.1016/j.braindev.2014.02.002. Epub 2014 Feb 28. PMID: 24582475.
4. Kitley J, Woodhall M, Waters P, Leite MI, Devenney E, Craig J, et al. Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype. Neurology. 2012 Sep 18;79(12):1273-7. doi: 10.1212/WNL.0b013e31826aac4e. Epub 2012 Aug 22. PMID: 22914827.
5. Mader S, Gredler V, Schanda K, Rostasy K, Dujmovic I, Pfaller K, et al. Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders. J Neuroinflammation. 2011 Dec 28;8:184. doi: 10.1186/1742-2094-8-184. PMID: 22204662; PMCID: PMC3278385.
6. Rostásy K, Mader S, Hennes EM, Schanda K, Gredler V, Guenther A, et al. Persisting myelin oligodendrocyte glycoprotein antibodies in aquaporin-4 antibody negative pediatric neuromyelitis optica. Mult Scler. 2013 Jul;19(8):1052-9. doi: 10.1177/1352458512470310. Epub 2012 Dec 20. PMID: 23257621.
7. Huppke P, Rostasy K, Karenfort M, Huppke B, Seidl R, Leiz S, et al. Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis in pediatric patients. Mult Scler. 2013 Jun;19(7):941-6. doi: 10.1177/1352458512466317. Epub 2012 Nov 5. PMID: 23128668.
8. Dos Passos GR, Oliveira LM, da Costa BK, Apostolos-Pereira SL, Callegaro D, Fujihara K, et al. MOG-IgG-Associated Optic Neuritis, Encephalitis, and Myelitis: Lessons Learned From Neuromyelitis Optica Spectrum Disorder. Front Neurol. 2018 Apr 4;9:217. doi: 10.3389/fneur.2018.00217. PMID: 29670575; PMCID: PMC5893792.
9. Jarius S, Kleiter I, Ruprecht K, Asgari N, Pitarokoili K, Borisow N, et al; in cooperation with the Neuromyelitis Optica Study Group (NEMOS). MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome. J Neuroinflammation. 2016 Nov 1;13(1):281. doi: 10.1186/s12974-016-0719-z. PMID: 27802825; PMCID: PMC5088671.
10. Jurynczyk M, Messina S, Woodhall MR, Raza N, Everett R, Roca-Fernandez A, et al. Clinical presentation and prognosis in MOG-antibody disease: a UK study. Brain. 2017 Dec 1;140(12):3128-38. doi: 10.1093/brain/awx276. Erratum in: Brain. 2018 Apr 1;141(4):e31. PMID: 29136091.
11. Ramanathan S, Mohammad S, Tantsis E, Nguyen TK, Merheb V, Fung VSC, et al; Australasian and New Zealand MOG Study Group. Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination. J Neurol Neurosurg Psychiatry. 2018 Feb;89(2):127-37. doi: 10.1136/jnnp-2017-316880. Epub 2017 Nov 15. PMID: 29142145; PMCID: PMC5800335.
12. Mohseni SH, Skejoe HPB, Wuerfel J, Paul F, Reindl M, Jarius S, et al. Leptomeningeal and Intraparenchymal Blood Barrier Disruption in a MOG-IgG-Positive Patient. Case Rep Neurol Med. 2018 Dec 9;2018:1365175. doi: 10.1155/2018/1365175. PMID: 30834146; PMCID: PMC6374805.
13. Haddad N, Roussel B, Pelcovits A, Rizvi S. Optic neuritis, encephalitis and leptomeningeal enhancement in a patient with anti-MOG antibodies: A case study. Mult Scler Relat Disord. 2019 Sep;34:14-16. doi: 10.1016/j.msard.2019.06.010. Epub 2019 Jun 14. PMID: 31226544.
14. Fujimori J, Nakamura M, Yagihashi T, Nakashima I. Clinical and Radiological Features of Adult Onset Bilateral Medial Frontal Cerebral Cortical Encephalitis With Anti-myelin Oligodendrocyte Glycoprotein Antibody. Front Neurol. 2020 Dec 16;11:600169. doi: 10.3389/fneur.2020.600169. PMID: 33391163; PMCID: PMC7772389.
15. Shen W, Zhang Y, Zhou C, Shen Y. Bilateral symmetrical deep gray matter involvement and leptomeningeal enhancement in a child with MOG-IgG-associated encephalomyelitis. BMC Neurol. 2021 Jan 8;21(1):10. doi: 10.1186/s12883-020-02041-3. PMID: 33419414; PMCID: PMC7791788.
16. Nakamura M, Iwasaki Y, Takahashi T, Kaneko K, Nakashima I, Kunieda T, et al. A case of MOG antibody-positive bilateral optic neuritis and meningoganglionitis following a genital herpes simplex virus infection. Mult Scler Relat Disord. 2017 Oct;17:148-150. doi: 10.1016/j.msard.2017.07.023. Epub 2017 Jul 27. PMID: 29055448.
17. Høglund RA, Myro AZ, Zarnovicky S, Holmøy T. A young woman with seizures, visual impairment, and paralysis. Tidsskr Nor Laegeforen. 2019 Aug 19;139(11). Norwegian, English. doi: 10.4045/tidsskr.19.0122. PMID: 31429234.
18. Denève M, Biotti D, Patsoura S, Ferrier M, Meluchova Z, Mahieu L, et al. MRI features of demyelinating disease associated with anti-MOG antibodies in adults. J Neuroradiol. 2019 Sep;46(5):312-8. doi: 10.1016/j.neurad.2019.06.001. Epub 2019 Jun 20. PMID: 31228536.

Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement

Year 2022, Volume: 6 Issue: 4, 540 - 542, 01.04.2022

Buket Tuğan Yıldız Deniz Tuncel Nursel Yurttutan Şerife Çöklü

https://doi.org/10.28982/josam.955602

Abstract

Anti-myelin oligodendrocyte (MOG)-positive cases have a variable clinical presentation. MOG autoantibodies are associated with acute disseminated encephalomyelitis, multiple sclerosis, clinically isolated syndrome, neuromyelitis optica, isolated optic neuritis, and transverse myelitis. Our patient had bilateral optic neuritis with acute tetraparesis. Cranial magnetic resonance imaging (MRI) showed leptomeningeal contrast involvement and contrast enhancement in all cranial nerve nuclei. Spinal MRI revealed leptomeningeal contrast enhancement, and a contrast-enhancing lesion was found in the cervical spinal cord.
This case is worth presenting because spinal leptomeningeal involvement is rare in anti-MOG-positive patients.

Keywords

Anti-MOG, Tetraparesis, Spinal, Leptomeningeal enhancement

References

1. Brunner C, Lassmann H, Waehneldt TV, Matthieu JM, Linington C. Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2',3'-cyclic nucleotide 3'-phosphodiesterase in the CNS of adult rats. J Neurochem. 1989 Jan;52(1):296-304. doi: 10.1111/j.1471-4159.1989.tb10930.x. PMID: 2462020.
2. Reindl M, Di Pauli F, Rostásy K, Berger T. The spectrum of MOG autoantibody-associated demyelinating diseases. Nat Rev Neurol. 2013 Aug;9(8):455-61. doi: 10.1038/nrneurol.2013.118. Epub 2013 Jun 25. PMID: 23797245.
3. Tsuburaya RS, Miki N, Tanaka K, Kageyama T, Irahara K, Mukaida S, et al. Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a Japanese boy with recurrent optic neuritis. Brain Dev. 2015 Jan;37(1):145-8. doi: 10.1016/j.braindev.2014.02.002. Epub 2014 Feb 28. PMID: 24582475.
4. Kitley J, Woodhall M, Waters P, Leite MI, Devenney E, Craig J, et al. Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype. Neurology. 2012 Sep 18;79(12):1273-7. doi: 10.1212/WNL.0b013e31826aac4e. Epub 2012 Aug 22. PMID: 22914827.
5. Mader S, Gredler V, Schanda K, Rostasy K, Dujmovic I, Pfaller K, et al. Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders. J Neuroinflammation. 2011 Dec 28;8:184. doi: 10.1186/1742-2094-8-184. PMID: 22204662; PMCID: PMC3278385.
6. Rostásy K, Mader S, Hennes EM, Schanda K, Gredler V, Guenther A, et al. Persisting myelin oligodendrocyte glycoprotein antibodies in aquaporin-4 antibody negative pediatric neuromyelitis optica. Mult Scler. 2013 Jul;19(8):1052-9. doi: 10.1177/1352458512470310. Epub 2012 Dec 20. PMID: 23257621.
7. Huppke P, Rostasy K, Karenfort M, Huppke B, Seidl R, Leiz S, et al. Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis in pediatric patients. Mult Scler. 2013 Jun;19(7):941-6. doi: 10.1177/1352458512466317. Epub 2012 Nov 5. PMID: 23128668.
8. Dos Passos GR, Oliveira LM, da Costa BK, Apostolos-Pereira SL, Callegaro D, Fujihara K, et al. MOG-IgG-Associated Optic Neuritis, Encephalitis, and Myelitis: Lessons Learned From Neuromyelitis Optica Spectrum Disorder. Front Neurol. 2018 Apr 4;9:217. doi: 10.3389/fneur.2018.00217. PMID: 29670575; PMCID: PMC5893792.
9. Jarius S, Kleiter I, Ruprecht K, Asgari N, Pitarokoili K, Borisow N, et al; in cooperation with the Neuromyelitis Optica Study Group (NEMOS). MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome. J Neuroinflammation. 2016 Nov 1;13(1):281. doi: 10.1186/s12974-016-0719-z. PMID: 27802825; PMCID: PMC5088671.
10. Jurynczyk M, Messina S, Woodhall MR, Raza N, Everett R, Roca-Fernandez A, et al. Clinical presentation and prognosis in MOG-antibody disease: a UK study. Brain. 2017 Dec 1;140(12):3128-38. doi: 10.1093/brain/awx276. Erratum in: Brain. 2018 Apr 1;141(4):e31. PMID: 29136091.
11. Ramanathan S, Mohammad S, Tantsis E, Nguyen TK, Merheb V, Fung VSC, et al; Australasian and New Zealand MOG Study Group. Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination. J Neurol Neurosurg Psychiatry. 2018 Feb;89(2):127-37. doi: 10.1136/jnnp-2017-316880. Epub 2017 Nov 15. PMID: 29142145; PMCID: PMC5800335.
12. Mohseni SH, Skejoe HPB, Wuerfel J, Paul F, Reindl M, Jarius S, et al. Leptomeningeal and Intraparenchymal Blood Barrier Disruption in a MOG-IgG-Positive Patient. Case Rep Neurol Med. 2018 Dec 9;2018:1365175. doi: 10.1155/2018/1365175. PMID: 30834146; PMCID: PMC6374805.
13. Haddad N, Roussel B, Pelcovits A, Rizvi S. Optic neuritis, encephalitis and leptomeningeal enhancement in a patient with anti-MOG antibodies: A case study. Mult Scler Relat Disord. 2019 Sep;34:14-16. doi: 10.1016/j.msard.2019.06.010. Epub 2019 Jun 14. PMID: 31226544.
14. Fujimori J, Nakamura M, Yagihashi T, Nakashima I. Clinical and Radiological Features of Adult Onset Bilateral Medial Frontal Cerebral Cortical Encephalitis With Anti-myelin Oligodendrocyte Glycoprotein Antibody. Front Neurol. 2020 Dec 16;11:600169. doi: 10.3389/fneur.2020.600169. PMID: 33391163; PMCID: PMC7772389.
15. Shen W, Zhang Y, Zhou C, Shen Y. Bilateral symmetrical deep gray matter involvement and leptomeningeal enhancement in a child with MOG-IgG-associated encephalomyelitis. BMC Neurol. 2021 Jan 8;21(1):10. doi: 10.1186/s12883-020-02041-3. PMID: 33419414; PMCID: PMC7791788.
16. Nakamura M, Iwasaki Y, Takahashi T, Kaneko K, Nakashima I, Kunieda T, et al. A case of MOG antibody-positive bilateral optic neuritis and meningoganglionitis following a genital herpes simplex virus infection. Mult Scler Relat Disord. 2017 Oct;17:148-150. doi: 10.1016/j.msard.2017.07.023. Epub 2017 Jul 27. PMID: 29055448.
17. Høglund RA, Myro AZ, Zarnovicky S, Holmøy T. A young woman with seizures, visual impairment, and paralysis. Tidsskr Nor Laegeforen. 2019 Aug 19;139(11). Norwegian, English. doi: 10.4045/tidsskr.19.0122. PMID: 31429234.
18. Denève M, Biotti D, Patsoura S, Ferrier M, Meluchova Z, Mahieu L, et al. MRI features of demyelinating disease associated with anti-MOG antibodies in adults. J Neuroradiol. 2019 Sep;46(5):312-8. doi: 10.1016/j.neurad.2019.06.001. Epub 2019 Jun 20. PMID: 31228536.

There are 18 citations in total.

Details

Primary Language	English
Subjects	Neurology and Neuromuscular Diseases
Journal Section	Case report
Authors	Buket Tuğan Yıldız 0000-0001-6783-2336 Deniz Tuncel 0000-0003-2347-472X Nursel Yurttutan 0000-0002-3685-6025 Şerife Çöklü This is me 0000-0001-6490-0727
Publication Date	April 1, 2022
Published in Issue	Year 2022 Volume: 6 Issue: 4

Cite

APA	Tuğan Yıldız, B., Tuncel, D., Yurttutan, N., Çöklü, Ş. (2022). Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement. Journal of Surgery and Medicine, 6(4), 540-542. https://doi.org/10.28982/josam.955602
AMA	Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü Ş. Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement. J Surg Med. April 2022;6(4):540-542. doi:10.28982/josam.955602
Chicago	Tuğan Yıldız, Buket, Deniz Tuncel, Nursel Yurttutan, and Şerife Çöklü. “Rare Nervous System Involvement in an Anti-Myelin Oligodendrocyte-Positive Case: Spinal Leptomeningeal Involvement”. Journal of Surgery and Medicine 6, no. 4 (April 2022): 540-42. https://doi.org/10.28982/josam.955602.
EndNote	Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü Ş (April 1, 2022) Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement. Journal of Surgery and Medicine 6 4 540–542.
IEEE	B. Tuğan Yıldız, D. Tuncel, N. Yurttutan, and Ş. Çöklü, “Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement”, J Surg Med, vol. 6, no. 4, pp. 540–542, 2022, doi: 10.28982/josam.955602.
ISNAD	Tuğan Yıldız, Buket et al. “Rare Nervous System Involvement in an Anti-Myelin Oligodendrocyte-Positive Case: Spinal Leptomeningeal Involvement”. Journal of Surgery and Medicine 6/4 (April 2022), 540-542. https://doi.org/10.28982/josam.955602.
JAMA	Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü Ş. Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement. J Surg Med. 2022;6:540–542.
MLA	Tuğan Yıldız, Buket et al. “Rare Nervous System Involvement in an Anti-Myelin Oligodendrocyte-Positive Case: Spinal Leptomeningeal Involvement”. Journal of Surgery and Medicine, vol. 6, no. 4, 2022, pp. 540-2, doi:10.28982/josam.955602.
Vancouver	Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü Ş. Rare nervous system involvement in an anti-myelin oligodendrocyte-positive case: spinal leptomeningeal involvement. J Surg Med. 2022;6(4):540-2.

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