Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disease and its prevalence has been projected to double over the next 30 years. The diagnosis of PD is bradykinesia and resting tremor or rigidity. PD is a progressive neurodegenerative disease with both motor and nonmotor symptoms. There are many medical options for the treatment of PD but levodopa remains the mainstay. Deep brain stimulation (DBS) is a safe neurosurgical symptomatic treatment for eligible patients with advanced disease in whom medical therapy fails to provide adequate symptom control and a good quality of life or in whom dopaminergic drugs cause severe side effects such as dyskinesias. In this case report, a 44-year-old female patient with a history of tremor and genetic Parkinson's disease, who presented to the clinic with the complaint of excessive increase in tremor in recent years, firstly with drug treatment and then with DBS treatment is reported.
References
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- Charles D, Konrad PE, Neimat J, Molinari AL, Tramontana MG, Fider SG, et al., Subthalamic nucleus deep brain stimulation in early-stage Parkinson's disease. Parkinsonism Relat Disord, 2014;20(7):731-7.
- Schuepbach WM, Rau K, Knudsen J, Volkmann P, Krack L, Timmermann TD, et al., Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med, 2013. 368(7): p. 610-22.
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Abstract
References
- . Reich SG, Savitt JM, Parkinson's Disease. Med Clin North Am, 2019;103(2):337-350.
- Hariz M, Blomstedt P. Deep brain stimulation for Parkinson's disease. J Intern Med, 2022;292(5): 764-778.
- Church FC., Treatment Options for Motor and Non-Motor Symptoms of Parkinson's Disease. Biomolecules, 2021;11(4):612.
- França, C., Carra RB, Diniz JM, Munhoz RP, Cury RG. Deep brain stimulation in Parkinson's disease: state of the art and future perspectives. Arq Neuropsiquiatr, 2022;80(5 Suppl 1):105-115.
- Charles D, Konrad PE, Neimat J, Molinari AL, Tramontana MG, Fider SG, et al., Subthalamic nucleus deep brain stimulation in early-stage Parkinson's disease. Parkinsonism Relat Disord, 2014;20(7):731-7.
- Schuepbach WM, Rau K, Knudsen J, Volkmann P, Krack L, Timmermann TD, et al., Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med, 2013. 368(7): p. 610-22.
- Deuschl G, Schüpbach M, Knudsen K, Pinsker MO, Cornu P, Rau J, et al., Stimulation of the subthalamic nucleus at an earlier disease stage of Parkinson's disease: concept and standards of the EARLYSTIM-study. Parkinsonism Relat Disord, 2013. 19(1): p. 56-61.
Details
| Primary Language | English |
|---|---|
| Subjects | Radiology and Organ Imaging, Clinical Sciences (Other) |
| Journal Section | Case reports |
| Authors | |
| Publication Date | March 28, 2024 |
| Published in Issue | Year 2024 Volume: 10 Issue: 1 |
e-ISSN 2149-7796