Abstract
Datura stramonium belladona alkaloid ailesinin bir üyesi olan halüsinojenik bir bitkidir. Fazla miktarda alındığında halüsinasyon, ajitasyon ve deliryuma neden olabilir. Genellikle kurutulmuş yapraklarından hazırlanan sigaralar astım ve bronşit tedavisi için kullanılırken, tohumları akne, egzema, hemoroid tedavisinde ve antispazmotik amaçlı oral yolla alınmaktadır. Tedavi amacıyla bilinçsiz kullanımı, kazara gıda olarak kullanımı veya halusinojen etkilerinden yararlanmak amacıyla kötüye kullanılması sonucu ölümcül olabilecek antikolinerjik toksisiteye neden olabilmektedir. Bu yazıda da Datura stramonium yapraklarından yapılan dolma yemeği yedikten sonra ciltte kızarıklık ve deliryum ile hastaneye getirilen ve Datura stramonium toksisitesine maruz kalan bir çocuk hasta sunulmuştur. Nedeni bilinmeyen deliryum veya antikolinerjik bulgularla başvuran hastaların öyküsünde toksik etkili ilaç, madde ve bitki alımı mutlaka sorgulanmalıdır.
Keywords
Supporting Institution
YOKTUR
Project Number
YOKTUR
References
- Greene GS, Patterson SG, Warner E. Ingestion of angel’s trumpet: An increasingly common source of toxicity. South Med J 1996;89:365–369.
- Baker JR, Lee A, Ballent C. The Encyclopedia of physchoactive plants. Park Street Press 2005 ISBN 978-0-89281-978-2, translation of Rätsch C. Enzyklopedia der Psychoactiven Pflanzen. AT Verlag Aarau/Switzerland 1998.
- Vanderhoff BT, Mosser KH. Jimson weed toxicity: Management of anticholinergic plant ingestion. Am Fam Physician 1992;46:526-530.
- Datura Stramonium; Yeşil meyveleri ve beyaz şekilli çiçeği en.wikipedia.org, oluşturulma tarihi: 07.07.2005, alıntılanma tarihi; 21.05.2021
- Spina SP, Taddei A. Teenagers with Jimpson weed (Datura stramonium) poisoning. Can J Emerg Med 2007;9(6):467-469.
- Sever M, Cekin M. Anticholinergic intoxication due to Datura stromonium: three pediatric cases. Akademik Acil Tıp Dergisi 2007;5(4):128-301.
- TC Tarım ve Orman Bakanlığı İstanbul İl Tarım ve Orman Müdürlüğü. Haber: Ispanaktan kaynaklandığı iddia edilen zehirlenme vakaları hakkında basın açıklamasi.https://istanbul.tarimorman.gov.tr/Haber/1009/Ispanaktan-Kaynaklandigi-İddia Edilen Zehirlenme Vakalari Hakkinda Basin Acıklamasi Erişim Tarihi: 01.03.2022
- Disel NR, Yilmaz M, Kekeç Z. Karanlık M Poisoned after dinner: Dolma with Datura stramonium. Turk J Emerg Med 2016;15;51-55.
- Wolf LR. Anticholinergic toxicity. In: Tintinalli JE, Kelen GD, Stapczynski JS (eds). Emergency Medicine (seventh ed). New York, McGraw-Hill Co. 2010;1182–1185.
- Salen P, Shih R, Sierzenskski P, et al. Effect of Physostigmine and Gastric Lavage in a Datura Stramonium-Induced Anticholinergic Poisoning Epidemic. Am J Emerg Med. 2003;21:316-317.
- Wax PM, Young AC. Anticholinergics. In: Tintinalli JE, Stapczynski JS, Ma OJ, Cline DM, Cydulka RK, Meckler GD, editors. Tintinalli’s emergency medicine: A comprehensive study guide. 7th ed. New York, NY: McGraw-Hill; 2011. p. 1305-1308.
- Rakotomavo F, Andriamasy C, Rasamoelina N, Raveloson N. Datura stramonium intoxication in two children. Pediatr Int 2014;56(3):e14-6. doi: 10.1111/ped.12363.
- Arens AM, Shah K, Al-Abri S, Olson KR, Kearney T. Safety and effectiveness of physostigmine: a 10- year retrospective review. Clinical Toxıcology 2018:56;101–107.
Abstract
Datura stramonium is a hallucinogenic herb, a member of the belladonna alkaloid family. When taken in large amounts, it can cause hallucinations, agitation and delirium. Generally, cigarettes prepared from the dried leaves are used for the treatment of asthma and bronchitis, while the seeds are taken orally for the treatment of acne, eczema, hemorrhoids and for antispasmodic purposes. It can cause fatal anticholinergic poisoning as a result of unconscious use for treatment, accidental use as food or abuse to benefit from hallucinogen effects. In this article, a child patient who was brought to the hospital with skin rash and delirium after eating a stuffed meal made from Datura stramonium leaves and diagnosed with Datura stramonium poisoning was presented. The intake of toxic drugs, substances, and herbs should be questioned whose in the medical history of patients presenting with delirium or anticholinergic findings of unknown origin.
Keywords
Project Number
YOKTUR
References
- Greene GS, Patterson SG, Warner E. Ingestion of angel’s trumpet: An increasingly common source of toxicity. South Med J 1996;89:365–369.
- Baker JR, Lee A, Ballent C. The Encyclopedia of physchoactive plants. Park Street Press 2005 ISBN 978-0-89281-978-2, translation of Rätsch C. Enzyklopedia der Psychoactiven Pflanzen. AT Verlag Aarau/Switzerland 1998.
- Vanderhoff BT, Mosser KH. Jimson weed toxicity: Management of anticholinergic plant ingestion. Am Fam Physician 1992;46:526-530.
- Datura Stramonium; Yeşil meyveleri ve beyaz şekilli çiçeği en.wikipedia.org, oluşturulma tarihi: 07.07.2005, alıntılanma tarihi; 21.05.2021
- Spina SP, Taddei A. Teenagers with Jimpson weed (Datura stramonium) poisoning. Can J Emerg Med 2007;9(6):467-469.
- Sever M, Cekin M. Anticholinergic intoxication due to Datura stromonium: three pediatric cases. Akademik Acil Tıp Dergisi 2007;5(4):128-301.
- TC Tarım ve Orman Bakanlığı İstanbul İl Tarım ve Orman Müdürlüğü. Haber: Ispanaktan kaynaklandığı iddia edilen zehirlenme vakaları hakkında basın açıklamasi.https://istanbul.tarimorman.gov.tr/Haber/1009/Ispanaktan-Kaynaklandigi-İddia Edilen Zehirlenme Vakalari Hakkinda Basin Acıklamasi Erişim Tarihi: 01.03.2022
- Disel NR, Yilmaz M, Kekeç Z. Karanlık M Poisoned after dinner: Dolma with Datura stramonium. Turk J Emerg Med 2016;15;51-55.
- Wolf LR. Anticholinergic toxicity. In: Tintinalli JE, Kelen GD, Stapczynski JS (eds). Emergency Medicine (seventh ed). New York, McGraw-Hill Co. 2010;1182–1185.
- Salen P, Shih R, Sierzenskski P, et al. Effect of Physostigmine and Gastric Lavage in a Datura Stramonium-Induced Anticholinergic Poisoning Epidemic. Am J Emerg Med. 2003;21:316-317.
- Wax PM, Young AC. Anticholinergics. In: Tintinalli JE, Stapczynski JS, Ma OJ, Cline DM, Cydulka RK, Meckler GD, editors. Tintinalli’s emergency medicine: A comprehensive study guide. 7th ed. New York, NY: McGraw-Hill; 2011. p. 1305-1308.
- Rakotomavo F, Andriamasy C, Rasamoelina N, Raveloson N. Datura stramonium intoxication in two children. Pediatr Int 2014;56(3):e14-6. doi: 10.1111/ped.12363.
- Arens AM, Shah K, Al-Abri S, Olson KR, Kearney T. Safety and effectiveness of physostigmine: a 10- year retrospective review. Clinical Toxıcology 2018:56;101–107.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Articles |
| Authors | |
| Project Number | YOKTUR |
| Publication Date | April 30, 2022 |
| Submission Date | June 28, 2021 |
| Acceptance Date | September 29, 2021 |
| Published in Issue | Year 2022 Volume: 15 Issue: 1 |
Cite
Cited By
Seven Siblings Admitted to Emergency with Datura Poisoning: Cases from Northern Syria
Eurasian Journal of Toxicology
https://doi.org/10.51262/ejtox.1221282
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