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Year 2021, Volume: 38 Issue: 2, 61 - 65, 03.04.2021

Ayşen Taslak Şengül Yasemin Büyükkarabacak Zuhal Altunkaynak Gamze Altun Bilal Şengül Selçuk Gürz Mehmet Pirzirenli Ahmet Başoğlu

Abstract

Supporting Institution

Ondokuz Mayıs Üniversitesi Bilimsel Araştırma Projesi tarafından desteklenmiştir.

Project Number

1901.09.014

References

  • Altunkaynak BZ, Ozbek E., 2009. Overweight and structural alterations of the liver in female rats fed a high-fat diet: a stereological and histological study. Turk J Gastroenterol 20:93-103.
  • Bostanci K, Ozalper MH, Eldem B, Ozyurtkan MO, Issaka A, Ermerak NO, Yüksel M., 2013. Quality of life of patients who have undergone the minimally invasive repair of pectus carinatum.Eur. J. Cardiothorac. Surg 43:122-126.
  • Calik M, Aribas OK, Kanat F., 2007. The effect of costal cartilage resection on the chest wall development: a morphometric evaluation. Eur J Cardiothorac Surg 32:756-760.
  • Fokin A.A. , Robicsek F., 2006. Acquired deformities of the anterior chest wall J Thorac Cardiovasc Surg 54: 57-61.
  • Goertzen M, Baltzer A, Schulitz KP., 1993. Long-term results after operation for funnel chest. Arch Orthop Trauma Surg 112:289-291.
  • Haje S.A., 1995. Iatrogenic pectus carinatum: A case report Int Orthop (SICOT) 19: 370-373.
  • Ji Y, Liu W, Chen S, Xu B, Tang Y, Wang X, Yang G, Cao L., 2011. Assessment of psychosocial functioning and its risk factors in children with pectus excavatum. Health Qual. Life Outcomes 9: 28.
  • Lomholt J.J. , Jacobsen E.B. , Thastum M., Pilegaard H., 2016. A prospective study on quality of life in youths after pectus excavatum correction.Annals Cardiothorac Surg 456-465.
  • Kelly RE Jr, Shamberger RC, Mellins RB, Mitchell KK, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW, Shim WKT, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley TC, Alan B Moskowitz AB., 2007. Prospective multicenter study of surgical correction of pectus excavatum: Design, perioperative complications, pain, and baseline pulmonary function facilitated by internet-based data collection. J Am Coll Surg 205: 205-216.
  • Kelly RE Jr, Cash TF, Shamberger RC, Mitchell KK, Mellins RB. Mitchell KK, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW, Shim WKT, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley TC, Alan B Moskowitz AB., 2008. Surgical repair of pectus excavatum markedly improves body image and perceived ability for physical activity: multicenter study. Pediatrics 122: 1218-1222.
  • Lam MW, Klassen AF, Montgomery CJ, LeBlanc JG, Skarsgard ED., 2008. Quality-of-life outcomes after surgical correction of pectus excavatum: a comparison of the Ravitch and Nuss procedures. J Pediatr Surg 43:819-825.
  • Malek H.M. , Fonkalsrud E.W. , Cooper C.B., 2003. Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum. Chest 124: 870-882.
  • Moon DH, Kang MK, Lee HS, Lee S., 2019. Long-Term Results of Compressive Brace Therapy for Pectus Carinatum. Thorac Cardiovasc Surg. 67:67-72.
  • Quigley PM, Haller JA Jr, Jelus KL, Loughlin GM, Marcus CL., 1996. Cardiorespiratory function before and after corrective surgery in pectus excavatum. J Pediatr 128:638-643.
  • Roberts N, Puddephat MJ, McNulty V., 2000. The benefit of stereology for quantitative radiology. Br J Radiol 73:679-697.
  • Robicsek F. , Fokin A.A., 2004. How not to do it: Restrictive thoracic dystrophy after pectus excavatum repair Interact Cardiovasc Thorac Surg 3:566-568.
  • Robicsek F, Watts LT, Fokin AA., 2009. Surgical Repair of Pectus Excavatum and Carinatum. Semin Thorac Cardiovasc Surg. 21:64-75.
  • Shamberger R.C., 2000.Cardiopulmonary effects of anterior chest wall deformities Chest Surg Clin North Am 10: 245-252.
  • Sengul AT, Sahin B, Celenk C, Basoglu A, Sengul B., 2014. The effect of minimally invasive surgical repair on the lung volumes of patients with pectus excavatum. Thorac Cardiovasc Surg 62:226-230.

Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study)

Year 2021, Volume: 38 Issue: 2, 61 - 65, 03.04.2021

Ayşen Taslak Şengül Yasemin Büyükkarabacak Zuhal Altunkaynak Gamze Altun Bilal Şengül Selçuk Gürz Mehmet Pirzirenli Ahmet Başoğlu

Abstract

Background: Surgical treatment of chest wall deformities is done with costal cartilage resection in selected patients in adolescence. In this study, we evaluated the effect of costal cartilage resections on the lung volume by using computed tomography with stereologically.
Methods: In this study, sixteen 4-weeks-old New Zealand rabbits were employed.
Young subjects were preferred to evaluate the effect of the operation on the growth process. In order to avoid postoperative complications, only 2 costal cartilage resection was performed. The surgical group was resected to the right 4 and 5 costal cartilages (n = 8). The group that was not operated was accepted as the control group (n=8). The growth of the subjects was followed.
Computed thorax tomography (CTT) scans of all animals were performed preoperatively and at the 4th postoperative week. Estimation of pre- and postoperative lung volumes was performed with the Cavalieri principle.
Results: In the control group followed up during growth, bilateral lung volume was increased (15.75% and 20.62% respectively right and left lungs). In the surgical group, both the surgical side and the opposite lung volume decreased after costal cartilage resection (20.09% and 1.07% respectively right and left lungs).
Conclusions: Even though the number of resected cartilage was limited, total lung volume decreased after costal cartilage resection. In the treatment of chest wall deformities, costal cartilage resection should be considered as the last option in children.

Keywords

Pectus excavatum Cavalieri principal Costal cartilage Lung

Project Number

1901.09.014

References

  • Altunkaynak BZ, Ozbek E., 2009. Overweight and structural alterations of the liver in female rats fed a high-fat diet: a stereological and histological study. Turk J Gastroenterol 20:93-103.
  • Bostanci K, Ozalper MH, Eldem B, Ozyurtkan MO, Issaka A, Ermerak NO, Yüksel M., 2013. Quality of life of patients who have undergone the minimally invasive repair of pectus carinatum.Eur. J. Cardiothorac. Surg 43:122-126.
  • Calik M, Aribas OK, Kanat F., 2007. The effect of costal cartilage resection on the chest wall development: a morphometric evaluation. Eur J Cardiothorac Surg 32:756-760.
  • Fokin A.A. , Robicsek F., 2006. Acquired deformities of the anterior chest wall J Thorac Cardiovasc Surg 54: 57-61.
  • Goertzen M, Baltzer A, Schulitz KP., 1993. Long-term results after operation for funnel chest. Arch Orthop Trauma Surg 112:289-291.
  • Haje S.A., 1995. Iatrogenic pectus carinatum: A case report Int Orthop (SICOT) 19: 370-373.
  • Ji Y, Liu W, Chen S, Xu B, Tang Y, Wang X, Yang G, Cao L., 2011. Assessment of psychosocial functioning and its risk factors in children with pectus excavatum. Health Qual. Life Outcomes 9: 28.
  • Lomholt J.J. , Jacobsen E.B. , Thastum M., Pilegaard H., 2016. A prospective study on quality of life in youths after pectus excavatum correction.Annals Cardiothorac Surg 456-465.
  • Kelly RE Jr, Shamberger RC, Mellins RB, Mitchell KK, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW, Shim WKT, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley TC, Alan B Moskowitz AB., 2007. Prospective multicenter study of surgical correction of pectus excavatum: Design, perioperative complications, pain, and baseline pulmonary function facilitated by internet-based data collection. J Am Coll Surg 205: 205-216.
  • Kelly RE Jr, Cash TF, Shamberger RC, Mitchell KK, Mellins RB. Mitchell KK, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW, Shim WKT, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley TC, Alan B Moskowitz AB., 2008. Surgical repair of pectus excavatum markedly improves body image and perceived ability for physical activity: multicenter study. Pediatrics 122: 1218-1222.
  • Lam MW, Klassen AF, Montgomery CJ, LeBlanc JG, Skarsgard ED., 2008. Quality-of-life outcomes after surgical correction of pectus excavatum: a comparison of the Ravitch and Nuss procedures. J Pediatr Surg 43:819-825.
  • Malek H.M. , Fonkalsrud E.W. , Cooper C.B., 2003. Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum. Chest 124: 870-882.
  • Moon DH, Kang MK, Lee HS, Lee S., 2019. Long-Term Results of Compressive Brace Therapy for Pectus Carinatum. Thorac Cardiovasc Surg. 67:67-72.
  • Quigley PM, Haller JA Jr, Jelus KL, Loughlin GM, Marcus CL., 1996. Cardiorespiratory function before and after corrective surgery in pectus excavatum. J Pediatr 128:638-643.
  • Roberts N, Puddephat MJ, McNulty V., 2000. The benefit of stereology for quantitative radiology. Br J Radiol 73:679-697.
  • Robicsek F. , Fokin A.A., 2004. How not to do it: Restrictive thoracic dystrophy after pectus excavatum repair Interact Cardiovasc Thorac Surg 3:566-568.
  • Robicsek F, Watts LT, Fokin AA., 2009. Surgical Repair of Pectus Excavatum and Carinatum. Semin Thorac Cardiovasc Surg. 21:64-75.
  • Shamberger R.C., 2000.Cardiopulmonary effects of anterior chest wall deformities Chest Surg Clin North Am 10: 245-252.
  • Sengul AT, Sahin B, Celenk C, Basoglu A, Sengul B., 2014. The effect of minimally invasive surgical repair on the lung volumes of patients with pectus excavatum. Thorac Cardiovasc Surg 62:226-230.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Experimental Research
Authors

Ayşen Taslak Şengül

Yasemin Büyükkarabacak

Zuhal Altunkaynak

Gamze Altun

Bilal Şengül This is me 0000-0002-2605-8740

Selçuk Gürz

Mehmet Pirzirenli This is me 0000-0002-1831-2710

Ahmet Başoğlu

Project Number 1901.09.014
Publication Date April 3, 2021
Submission Date June 22, 2020
Acceptance Date December 9, 2020
Published in Issue Year 2021 Volume: 38 Issue: 2

Cite

APA Taslak Şengül, A., Büyükkarabacak, Y., Altunkaynak, Z., Altun, G., et al. (2021). Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study). Journal of Experimental and Clinical Medicine, 38(2), 61-65.
AMA Taslak Şengül A, Büyükkarabacak Y, Altunkaynak Z, Altun G, Şengül B, Gürz S, Pirzirenli M, Başoğlu A. Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study). J. Exp. Clin. Med. April 2021;38(2):61-65.
Chicago Taslak Şengül, Ayşen, Yasemin Büyükkarabacak, Zuhal Altunkaynak, Gamze Altun, Bilal Şengül, Selçuk Gürz, Mehmet Pirzirenli, and Ahmet Başoğlu. “Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study)”. Journal of Experimental and Clinical Medicine 38, no. 2 (April 2021): 61-65.
EndNote Taslak Şengül A, Büyükkarabacak Y, Altunkaynak Z, Altun G, Şengül B, Gürz S, Pirzirenli M, Başoğlu A (April 1, 2021) Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study). Journal of Experimental and Clinical Medicine 38 2 61–65.
IEEE A. Taslak Şengül, “Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study)”, J. Exp. Clin. Med., vol. 38, no. 2, pp. 61–65, 2021.
ISNAD Taslak Şengül, Ayşen et al. “Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study)”. Journal of Experimental and Clinical Medicine 38/2 (April 2021), 61-65.
JAMA Taslak Şengül A, Büyükkarabacak Y, Altunkaynak Z, Altun G, Şengül B, Gürz S, Pirzirenli M, Başoğlu A. Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study). J. Exp. Clin. Med. 2021;38:61–65.
MLA Taslak Şengül, Ayşen et al. “Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study)”. Journal of Experimental and Clinical Medicine, vol. 38, no. 2, 2021, pp. 61-65.
Vancouver Taslak Şengül A, Büyükkarabacak Y, Altunkaynak Z, Altun G, Şengül B, Gürz S, Pirzirenli M, Başoğlu A. Does Costal Cartilage Resection Reduce Lung Volume ? (An Experimental Stereological Study). J. Exp. Clin. Med. 2021;38(2):61-5.
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