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CHANGES IN THE DEMOGRAPHIC AND CLINICAL FEATURES OF COLORECTAL CARCINOMA CASES FOLLOWING THE COVID-19 PANDEMIC

Year 2022, Volume: 29 Issue: 3, 390 - 396, 30.09.2022
https://doi.org/10.17343/sdutfd.1105454

Abstract

Objective
This study aimed to compare the demographic, clinical
and pathological features of patients with colorectal
carcinomas presenting before and after the Covid-19
pandemic.
Material and Method
Subjects presenting from 9 months prior to and those
clinipresenting
within the first 9 months of the pandemic
were included in the study. The primary outcome
measure of this study was the difference in the clinical
and pathological features of the patients with invasive
colorectal carcinomas during the two periods.
Results
Pre-pandemic and post-pandemic patients were
similar with respect to age, gender, tumor location,
tumor size, lymph node invasion, differentiation,
presence of synchronous tumor, radial and
distal surgical margin positivity, perineural and
lymphovascular invasion, TNM stage, and liver
metastasis and recurrence. Although the difference
was not statistically significant when compared to the
pre-pandemic period, we identified 3 patients (4.7%)
with ileus and 2 patients with tumor perforation (3.2%)
among post-pandemic patients.
Conclusion
Our findings show a slight decrease in the number of
patients undergoing surgery for colorectal carcinomas
in the post-pandemic period compared to the prepandemic
period, probably due to the structural
changes in health-care organization in hospitals
and patients’ hesitation to apply for healthcare due
to possible infection with SARS-CoV-2. It is evident
that healthcare systems should strive to find new
ways to manage serious clinical conditions such as
malignancies during the Covid-19 pandemic.

References

  • 1. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA 2020;323(11):1061-9.
  • 2. Ge H, Wang X, Yuan X, Xiao G, Wang C, Deng T, et al. The epidemiology and clinical information about COVID-19. Eur J Clin Microbiol Infect Dis 2020;39(6):1011-9.
  • 3. Blumenthal D, Fowler EJ, Abrams M, Collins SR. Covid-19—implications for the health care system. Mass Medical Soc; 2020. p. 1483-8.
  • 4. King JS. Covid-19 and the need for health care reform. N Engl J Med 2020;382(26):e104.
  • 5. Mafham MM, Spata E, Goldacre R, Gair D, Curnow P, Bray M, et al. COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England. Lancet 2020;396(10248):381-9.
  • 6. Rodriguez-Leor O, Cid-Alvarez B, Ojeda S, Martín-Moreiras J, Rumoroso JR, López-Palop R, et al. Impact of the COVID-19 pandemic on interventional cardiology activity in Spain. REC Interv Cardiol 2020;2(2):82-9.
  • 7. Yıldırım M, Geçer E, Akgül Ö. The impacts of vulnerability, perceived risk, and fear on preventive behaviours against COVID-19. Psychol Health Med 2021;26(1):35-43.
  • 8. Silistre ES, Hatipoglu HU, Yesilbas O, Gurbuz FS, Ozturk E, Yalcinkaya A. Investigating the psychological impact of COVID-19 on healthcare workers in the intensive care unit. J Surg Med 2022;6(1):29-35.
  • 9. Ewing I, Hurley JJ, Josephides E, Millar A. The molecular genetics of colorectal cancer. Frontline Gastroenterol 2014;5(1):26-30.
  • 10. Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Prz Gastroenterol 2019;14(2):89-103.
  • 11. Mohammad MA, Koul S, Olivecrona GK, Gӧtberg M, Tydén P, Rydberg E, et al. Incidence and outcome of myocardial infarction treated with percutaneous coronary intervention during COVID-19 pandemic. Heart 2020;106(23):1812-8.
  • 12. Fersia O, Bryant S, Nicholson R, Mcmeeken K, Brown C, Donaldson B, et al. The impact of the COVID-19 pandemic on cardiology services. Open Heart 2020;7(2):e001359.
  • 13. Ersoy A. The frontline of the COVID-19 pandemic: Healthcare workers. Turk J Inter Med 2020;2(2):31-2.
  • 14. Demirag I, Fırtın CE, Bilbil ET. Managing expectations with emotional accountability: making City Hospitals accountable during the COVID-19 pandemic in Turkey. J Public Budg Account Financial Manag 2020;32(5):889-901
  • 15. Gul M, Yucesan M. Hospital preparedness assessment against COVID-19 pandemic: A case study in Turkish tertiary healthcare services. Math Probl Eng 2021;2021:1-18.
  • 16. Wallis CJ, Novara G, Marandino L, Bex A, Kamat AM, Karnes RJ, et al. Risks from deferring treatment for genitourinary cancers: a collaborative review to aid triage and management during the COVID-19 pandemic. Eur Urol 2020;78(1):29-42.
  • 17. Ward ZJ, Walbaum M, Walbaum B, Guzman MJ, De La Jara JJ, Nervi B, et al. Estimating the impact of the COVID-19 pandemic on diagnosis and survival of five cancers in Chile from 2020 to 2030: a simulation-based analysis. Lancet Oncol 2021;22(10):1427-37.
  • 18. Park JS, Huh JW, Park YA, Cho YB, Yun SH, Kim HC, et al. Prognostic Comparison Between Mucinous and Nonmucinous Adenocarcinoma in Colorectal Cancer. Medicine 2015;94(15):e658.
  • 19. Cantay H, Anuk T, Çetin T, Özcan H, Sulu B, Binnetoğlu K, et al. Evaluation of colorectal cancers in terms of diagnosis and treatment processes. Turk J Colorectal Dis 2021;31:239-245.

COVID-19 PANDEMİSİNİ TAKİBEN KOLOREKTAL KARSİNOM VAKALARININ DEMOGRAFİK VE KLİNİK ÖZELLİKLERİNDE MEYDANA GELEN DEĞİŞİKLİKLER

Year 2022, Volume: 29 Issue: 3, 390 - 396, 30.09.2022
https://doi.org/10.17343/sdutfd.1105454

Abstract

Amaç
Bu çalışma, Covid-19 pandemisinden önce ve sonra
başvuran kolorektal karsinomlu hastaların demografik,
klinik ve patolojik özelliklerini karşılaştırmayı
amaçladı.
Gereç ve Yöntem
Pandemiden 9 ay önce ve ilk 9 ay içinde başvuran
olgular çalışmaya dahil edildi. Bu çalışmanın birincil
sonuç ölçütü, iki dönem boyunca invaziv kolorektal
karsinomlu hastaların klinik ve patolojik özelliklerindeki
farklılıktı.
Bulgular
Pandemi öncesi ve pandemi sonrası hastalar yaş,
cinsiyet, tümör yerleşimi, tümör boyutu, lenf nodu invazyonu,
farklılaşma, senkron tümör varlığı, radyal
ve distal cerrahi sınır pozitifliği, perinöral ve lenfovasküler
invazyon, TNM evresi, karaciğer metastazı ve
nüks bakımından benzerdi. Pandemi öncesi döneme
göre fark istatistiksel olarak anlamlı olmasa da, pandemi
sonrası hastalarda ileuslu 3 hasta (%4,7) ve tümör
perforasyonu olan 2 hasta (%3,2) belirledik.
Sonuç: Bulgularımız, pandemi sonrası dönemde
kolorektal karsinom nedeniyle ameliyat olan hasta
sayısında, muhtemelen hastanelerdeki sağlık organizasyonundaki
yapısal değişiklikler ve hastaların
SARS-CoV-2 ile olası enfeksiyon nedeniyle sağlık
hizmetine başvuruda tereddüt etmesi nedeniyle pandemi
öncesi döneme göre hafif bir azalma olduğunu
göstermektedir. Sağlık sistemlerinin, Covid-19 salgını
sırasında maligniteler gibi ciddi klinik durumları yönetmenin
yeni yollarını bulmaya çalışması gerektiği
açıktır.

References

  • 1. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA 2020;323(11):1061-9.
  • 2. Ge H, Wang X, Yuan X, Xiao G, Wang C, Deng T, et al. The epidemiology and clinical information about COVID-19. Eur J Clin Microbiol Infect Dis 2020;39(6):1011-9.
  • 3. Blumenthal D, Fowler EJ, Abrams M, Collins SR. Covid-19—implications for the health care system. Mass Medical Soc; 2020. p. 1483-8.
  • 4. King JS. Covid-19 and the need for health care reform. N Engl J Med 2020;382(26):e104.
  • 5. Mafham MM, Spata E, Goldacre R, Gair D, Curnow P, Bray M, et al. COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England. Lancet 2020;396(10248):381-9.
  • 6. Rodriguez-Leor O, Cid-Alvarez B, Ojeda S, Martín-Moreiras J, Rumoroso JR, López-Palop R, et al. Impact of the COVID-19 pandemic on interventional cardiology activity in Spain. REC Interv Cardiol 2020;2(2):82-9.
  • 7. Yıldırım M, Geçer E, Akgül Ö. The impacts of vulnerability, perceived risk, and fear on preventive behaviours against COVID-19. Psychol Health Med 2021;26(1):35-43.
  • 8. Silistre ES, Hatipoglu HU, Yesilbas O, Gurbuz FS, Ozturk E, Yalcinkaya A. Investigating the psychological impact of COVID-19 on healthcare workers in the intensive care unit. J Surg Med 2022;6(1):29-35.
  • 9. Ewing I, Hurley JJ, Josephides E, Millar A. The molecular genetics of colorectal cancer. Frontline Gastroenterol 2014;5(1):26-30.
  • 10. Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Prz Gastroenterol 2019;14(2):89-103.
  • 11. Mohammad MA, Koul S, Olivecrona GK, Gӧtberg M, Tydén P, Rydberg E, et al. Incidence and outcome of myocardial infarction treated with percutaneous coronary intervention during COVID-19 pandemic. Heart 2020;106(23):1812-8.
  • 12. Fersia O, Bryant S, Nicholson R, Mcmeeken K, Brown C, Donaldson B, et al. The impact of the COVID-19 pandemic on cardiology services. Open Heart 2020;7(2):e001359.
  • 13. Ersoy A. The frontline of the COVID-19 pandemic: Healthcare workers. Turk J Inter Med 2020;2(2):31-2.
  • 14. Demirag I, Fırtın CE, Bilbil ET. Managing expectations with emotional accountability: making City Hospitals accountable during the COVID-19 pandemic in Turkey. J Public Budg Account Financial Manag 2020;32(5):889-901
  • 15. Gul M, Yucesan M. Hospital preparedness assessment against COVID-19 pandemic: A case study in Turkish tertiary healthcare services. Math Probl Eng 2021;2021:1-18.
  • 16. Wallis CJ, Novara G, Marandino L, Bex A, Kamat AM, Karnes RJ, et al. Risks from deferring treatment for genitourinary cancers: a collaborative review to aid triage and management during the COVID-19 pandemic. Eur Urol 2020;78(1):29-42.
  • 17. Ward ZJ, Walbaum M, Walbaum B, Guzman MJ, De La Jara JJ, Nervi B, et al. Estimating the impact of the COVID-19 pandemic on diagnosis and survival of five cancers in Chile from 2020 to 2030: a simulation-based analysis. Lancet Oncol 2021;22(10):1427-37.
  • 18. Park JS, Huh JW, Park YA, Cho YB, Yun SH, Kim HC, et al. Prognostic Comparison Between Mucinous and Nonmucinous Adenocarcinoma in Colorectal Cancer. Medicine 2015;94(15):e658.
  • 19. Cantay H, Anuk T, Çetin T, Özcan H, Sulu B, Binnetoğlu K, et al. Evaluation of colorectal cancers in terms of diagnosis and treatment processes. Turk J Colorectal Dis 2021;31:239-245.
There are 19 citations in total.

Details

Primary Language Turkish
Subjects Surgery, Clinical Sciences
Journal Section Research Articles
Authors

Dursun Burak Özdemir 0000-0002-3672-5738

Ahmet Karayiğit 0000-0003-0380-9190

Hayrettin Dizen 0000-0002-4031-2557

Bülent Ünal 0000-0003-2538-7961

Publication Date September 30, 2022
Submission Date April 19, 2022
Acceptance Date June 15, 2022
Published in Issue Year 2022 Volume: 29 Issue: 3

Cite

Vancouver Özdemir DB, Karayiğit A, Dizen H, Ünal B. COVID-19 PANDEMİSİNİ TAKİBEN KOLOREKTAL KARSİNOM VAKALARININ DEMOGRAFİK VE KLİNİK ÖZELLİKLERİNDE MEYDANA GELEN DEĞİŞİKLİKLER. Med J SDU. 2022;29(3):390-6.

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