Abstract
Yeni tip coronoviruss bağlı olan Coronovirus 19 hastalığı, 2019’dan beri tüm dünyanın sağlık problemi haline gelmiştir. Gebelik sürecinde de enfeksiyonun görülme sıklığı artmaktadır.
Gebelikte enfeksiyonun seyri asemptomatik, hafif bulgular (hipoksi ve pnömoni olmaksızın), viral pnömoni ve en nihayet ağır hastalık (akut solunumsal stres sendromu, sepsis, septik şok, pulmoner emboli veya akut koroner sendrom) şeklinde olmakla birlikte çoğunlukla asemptomatik bir seyir görülmektedir.
Enfekte anneden fetusa geçen virusun, fetusta nasıl bir etkiye yol açtığı ve antikorların koruyucu etkisi tam olarak netlik kazanmamıştır. Her ne kadar pek çok yenidoğan asemptomatik olsa da, yenidoğanın geçici takipnesi şeklinde bulgular görülebilmektedir.
Ek olarak, Coronovirus 19 hastalığının, kalp, beyin, akciğer, gastrointestinal sistem gibi bazı organ ve/veya sistemlere ait geç dönemde komplikasyonları da olabilmektedir.
Burada, gebeliğin son döneminde Coronovirus 19 hastalığı geçiren, sonrasında geçici ve aralıklı kardiyak disritmi bulguları olan bir vaka tartışılmıştır.
Keywords
References
- Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;20;382:727-33.
- Walker KF, O’Donoghue K, Grace N, Dorling J, Comeau JL, Li W, et al.. Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis. BJOG 2020;127:1324-36.
- Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, Kholin A, et al. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study. JAMA Pediatr 2021,1;175:817-26.
- Chen S, Huang B, Luo DJ, Li X, Yang F, Zhao Y, et al. [Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases]. Zhonghua Bing Li Xue Za Zhi 2020;49:418-23.
- Dong Y, Chi X, Hai H, Sun L, Zhang M, Xie WF, et al. Antibodies in the breast milk of a maternal woman with COVID-19. Emerg Microbes Infect 2020;9:1467-9.
- Centeno-Tablante E, Medina-Rivera M, Finkelstein JL, Rayco-Solon P, Garcia-Casal MN, Rogers L, et al. Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review. Ann N Y Acad Sci 2021;1484:32-54.
- Elshafeey F, Magdi R, Hindi N, Elshebiny M, Farrag N, Mahdy S, et al. A systematic scoping review of COVID-19 during pregnancy and childbirth. Int J Gynaecol Obstet 2020;150:47-52.
- World Health Organization. Clinical management of COVID-19: interim guidance (27 May 2020). Geneva, Switzerland: World Health Organization; 2020. https://www.who.int/publications/i/ item/clinical-management-of-covid-19.
- Faure-Bardon V, Isnard P, Roux N, Leruez-Ville M, Molina T, Bessieres B, et al. Protein expression of angiotensin-converting enzyme 2, a SARS-CoV-2-specific receptor, in fetal and placental tissues throughout gestation: new insight for perinatal counseling. Ultrasound Obstet Gynecol 2021;57:242-7.
- Twanow JE, McCabe C, Ream MA. The COVID-19 Pandemic and Pregnancy: Impact on Mothers and Newborns. Semin Pediatr Neurol 2022;42:100977. doi: 10.1016/j.spen.2022.100977.
- Helguera-Repetto AC, Villegas-Mota I, Arredondo-Pulido GI, Cardona-Pérez JA, León-Juárez M, Rivera-Rueda MA, et al. Cord Blood SARS-CoV-2 IgG Antibodies and Their Association With Maternal Immunity and Neonatal Outcomes. Front Pediatr 2022;10:883185.
- Long B, Brady WJ, Koyfman A, Gottlieb M. Cardiovascular complications in COVID-19. Am J Emerg Med 2020;38:1504-7.
- Lavelle MP, Desai AD, Wan EY. Arrhythmias in the COVID-19 patient. Heart Rhythm O2 2022;3:8-14.
- Mercedes BR, Serwat A, Naffaa L, Ramirez N, Khalid F, Steward SB, et al. New-onset myocardial injury in pregnant patients with coronavirus disease 2019: a case series of 15 patients. Am J Obstet Gynecol 2021;224:387.e1-387.e.
This is My COVID-19 History During Pregnancy and Breastfeeding Period: Maternal and Neonatal Outcomes
Abstract
The novel type coronoviruses spreaded all around the world, and caused a global health problem around the world since 2019. The number of pregnant women infected by new type of coronoviruses have been on the rise.
COVID-19 infection in pregnancy can be experienced with different symptoms as like asymptomatic infection, mild disease (no evidence of pneumonia or hypoxia), moderate disease (viral pneumonia), severe disease (severe pneumonia) or critical illness (acute respiratory distress syndrome, sepsis, septic shock, or complications such pulmonary embolism or acute coronary syndrome). Fortunately, most pregnant women infected with SARS-CoV-2 are asymptomatic, and most symptomatic women experience only mild or moderate cold/flu-like symptoms.
The effect of these viruses on the fetus, virus transmission from mother to baby and the protective role of antibodies are not clear yet. Although, the majority of newborns were asymptomatic; tachypnea, most likely secondary to transient tachypnea observed as the most common symptom.
On the other hand, late complications of the Coronovirus disease-19 can be presented in some organs and/or systems like heart, brain, lung, gastrointestinal system.
Here described a case, whose got Coronovirus disease-19 during third trimester of the pregnancy with transient cardiac dysrhythmia after Coronovirus disease-19.
References
- Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;20;382:727-33.
- Walker KF, O’Donoghue K, Grace N, Dorling J, Comeau JL, Li W, et al.. Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis. BJOG 2020;127:1324-36.
- Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, Kholin A, et al. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study. JAMA Pediatr 2021,1;175:817-26.
- Chen S, Huang B, Luo DJ, Li X, Yang F, Zhao Y, et al. [Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases]. Zhonghua Bing Li Xue Za Zhi 2020;49:418-23.
- Dong Y, Chi X, Hai H, Sun L, Zhang M, Xie WF, et al. Antibodies in the breast milk of a maternal woman with COVID-19. Emerg Microbes Infect 2020;9:1467-9.
- Centeno-Tablante E, Medina-Rivera M, Finkelstein JL, Rayco-Solon P, Garcia-Casal MN, Rogers L, et al. Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review. Ann N Y Acad Sci 2021;1484:32-54.
- Elshafeey F, Magdi R, Hindi N, Elshebiny M, Farrag N, Mahdy S, et al. A systematic scoping review of COVID-19 during pregnancy and childbirth. Int J Gynaecol Obstet 2020;150:47-52.
- World Health Organization. Clinical management of COVID-19: interim guidance (27 May 2020). Geneva, Switzerland: World Health Organization; 2020. https://www.who.int/publications/i/ item/clinical-management-of-covid-19.
- Faure-Bardon V, Isnard P, Roux N, Leruez-Ville M, Molina T, Bessieres B, et al. Protein expression of angiotensin-converting enzyme 2, a SARS-CoV-2-specific receptor, in fetal and placental tissues throughout gestation: new insight for perinatal counseling. Ultrasound Obstet Gynecol 2021;57:242-7.
- Twanow JE, McCabe C, Ream MA. The COVID-19 Pandemic and Pregnancy: Impact on Mothers and Newborns. Semin Pediatr Neurol 2022;42:100977. doi: 10.1016/j.spen.2022.100977.
- Helguera-Repetto AC, Villegas-Mota I, Arredondo-Pulido GI, Cardona-Pérez JA, León-Juárez M, Rivera-Rueda MA, et al. Cord Blood SARS-CoV-2 IgG Antibodies and Their Association With Maternal Immunity and Neonatal Outcomes. Front Pediatr 2022;10:883185.
- Long B, Brady WJ, Koyfman A, Gottlieb M. Cardiovascular complications in COVID-19. Am J Emerg Med 2020;38:1504-7.
- Lavelle MP, Desai AD, Wan EY. Arrhythmias in the COVID-19 patient. Heart Rhythm O2 2022;3:8-14.
- Mercedes BR, Serwat A, Naffaa L, Ramirez N, Khalid F, Steward SB, et al. New-onset myocardial injury in pregnant patients with coronavirus disease 2019: a case series of 15 patients. Am J Obstet Gynecol 2021;224:387.e1-387.e.
Details
| Primary Language | English |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | CASE REPORTS |
| Authors | |
| Early Pub Date | July 21, 2023 |
| Publication Date | September 25, 2023 |
| Submission Date | October 19, 2022 |
| Published in Issue | Year 2023 Volume: 17 Issue: 5 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.