Research Article
Year 2021,
, 709 - 713, 29.09.2021
Abstract
References
- 1. Tang TY, Rathnaweera HP, Kam JW, et al. Endovenous cyanoacrylate glue to treat varicose veins and chronic venous insufficiency Experience gained from our first 100. truncal venous ablations in a multi-ethnic Asian population using the Medtronic VenaSealTM Closure System. Phlebology. 2019;0(0):1-9.
- 2. Gibson K, Morrison N, Kolluri R, et al. Twenty-four month results from a randomized trial of cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2018;6:606-13.
- 3. Bademci MS, Kocaaslan C, Aldag M, et al. Single-center retrospective review of early outcomes of radiofrequency ablation versus cyanoacrylate ablation of isolated great saphenous vein insufficiency. J Vasc Surg Venous Lymphat Disord. 2019;7(4):480-485.
- 4. Gibson K, Ferris B. Cyanoacrylate closure of incompetent great, small and accessory saphenous veins without the use of post-procedure compression: Initial outcomes of a post-market evaluation of the VenaSeal System (the WAVES Study). Vascular. 2017; 25:149–156.
- 5. Proebstle TM, Alm J, Dimitri S, et al. The European multicenter cohort study on cyanoacrylate embolization of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2015;3:2-7.
- 6. Venaseal instructions for use, Medtronic Corporation, Dublin, Ireland, http://www.accessdata.fda.gov/ cdrh_docs/pdf14/P140018c.pdf (2015, accessed 16 May 2016).
- 7. De Maeseneer M. The endovenous revolution. Br J Surg. 2011;98(8):1037-8.
- 8. Rasmussen LH, Lawaetz M, Bjoern L, et al. Randomized clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy and surgical stripping for great saphenous varicose veins. Br J Surg. 2011; 98:1079–1087.
- 9. Morrison N, Gibson K, McEnroe S, et al. Randomized trial comparing cyanoacrylate embolization and radiofrequency ablation for incompetent great saphenous veins (VeClose). J Vasc Surg. 2015;61:985-994.
- 10. Ogilvy CS, Stieg PE, Awad I, et al. AHA Scientific Statement: Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association. Stroke. 2001;32:1458-71.
- 11. Rosen RJ, Contractor S. The use of cyanoacrylate adhesives in the management of congenital vascular malformations. Semin Intervent Radiol. 2004;21:59-66.
- 12. Almeida JI, Javier JJ, Mackay E, et al. First human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. J Vasc Surg Venous Lymphat Disord. 2013;1:174-80.
- 13. Almeida JI, Javier JJ, Mackay EG, et al. Two-year follow-up of first human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. Phlebology. 2015;30:397-404.
- 14. Morrison N, Gibson K, Vasquez M, et al. Five-year extension study of patients from a randomized clinical trial (VeClose) comparing cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2020;8:978–989.
- 15. Park I. Successful use of VenaSeal system for the treatment of large great saphenous vein of 2.84-cm diameter. Ann Surg Treat Res. 2018;94(4):219-221.
- 16. Anwar MA, Lane TR, Davies AH, et al. Complications of radiofrequency ablation of varicose veins. Phlebology. 2012;27(Suppl):34-9.
- 17. Dexter D, Kabnick L, Berland T, et al. Complications of endovenous lasers. Phlebology. 2012;27(Suppl):40-5.
- 18. Park I, Jeong MH, Park CJ, et al. Clinical features and management of ‘Phlebitis-like abnormal reaction’ after cyanoacrylate closure for the treatment of incompetent saphenous veins. Ann Vasc Surg. 2019;55:239–45.
- 19. Park I. Initial outcomes of cyanoacrylate closure, Venaseal system, for the treatment of the incompetent great and small saphenous veins. Vasc Endovascular Surg. 2017;51:545-9.
- 20. Gibson K, Minjarez R, Rinehardt E, et al. Frequency and severity of hypersensitivity reactions in patients after Venaseal™ cyanoacrylate treatment of superficial venous insufficiency. Phlebology. 2019;35(5):337-344.
- 21. Lew PS, Tan YK, Chong TT, et al. VenasealTM Cyanoacrylate Glue Rejection Following Endovenous Ablation -Another New Complication. Biomed J Sci & Tech Res. 2019;17(4):12993-12994.
Outcomes of Endovenous Cyanoacrylate Closure Using Venaseal ™ System for Chronic Venous Insufficiency
Abstract
Purpose: Endovenous cyanoacrylate closure of saphenous veins is a nonthermal, nonsclerosant ablation technique with satisfactory results. The objective of this study is to indicate the impact of Venaseal™ closure system in chronic venous insufficiency.
Methods: Between March 2014- March 2019, 27 patients underwent a total of 40 procedures with the VenaSeal ™ closure system for symptomatic saphenous vein reflux in our hospital. Beside glue ablation procedures, 16 patients underwent concomitant mini phlebectomy, 3 patients underwent perforan vein ligation and 1 patient underwent anterior accessory saphenous vein ligation. The mean age of the patients were 44.4±13.8 (19-67). Doppler ultrasound of the target vein was performed one and 12 months after treatment. Tumescent anesthesia and compression stockings were not used.
Results: Mean follow up time was 34.3 ±17 months. The anatomical success rate was 100% at 1 month and 100% at 1 year and there was no recanalization in treated vein segment. All procedures were well tolerated with a median visual analog scale (VAS) pain score of 3.0 (range: 2–5) on a 10-point scale. The mean pre-operative revised venous clinical severity score was 7.5±2.6, which improved to 2.6±0.7, p< 0.001 at one month follow-up. Deep vein thrombosis and pulmonary thromboembolism were not detected. Phlebitis was seen in 2 (7,4%) patients and hypersensitivity reaction occured in one patient (3,7%).
Conclusion: Endovenous cyanoacrylate closure of refluxing saphenous veins is a safe and effective method with reduced side effects.
References
- 1. Tang TY, Rathnaweera HP, Kam JW, et al. Endovenous cyanoacrylate glue to treat varicose veins and chronic venous insufficiency Experience gained from our first 100. truncal venous ablations in a multi-ethnic Asian population using the Medtronic VenaSealTM Closure System. Phlebology. 2019;0(0):1-9.
- 2. Gibson K, Morrison N, Kolluri R, et al. Twenty-four month results from a randomized trial of cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2018;6:606-13.
- 3. Bademci MS, Kocaaslan C, Aldag M, et al. Single-center retrospective review of early outcomes of radiofrequency ablation versus cyanoacrylate ablation of isolated great saphenous vein insufficiency. J Vasc Surg Venous Lymphat Disord. 2019;7(4):480-485.
- 4. Gibson K, Ferris B. Cyanoacrylate closure of incompetent great, small and accessory saphenous veins without the use of post-procedure compression: Initial outcomes of a post-market evaluation of the VenaSeal System (the WAVES Study). Vascular. 2017; 25:149–156.
- 5. Proebstle TM, Alm J, Dimitri S, et al. The European multicenter cohort study on cyanoacrylate embolization of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2015;3:2-7.
- 6. Venaseal instructions for use, Medtronic Corporation, Dublin, Ireland, http://www.accessdata.fda.gov/ cdrh_docs/pdf14/P140018c.pdf (2015, accessed 16 May 2016).
- 7. De Maeseneer M. The endovenous revolution. Br J Surg. 2011;98(8):1037-8.
- 8. Rasmussen LH, Lawaetz M, Bjoern L, et al. Randomized clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy and surgical stripping for great saphenous varicose veins. Br J Surg. 2011; 98:1079–1087.
- 9. Morrison N, Gibson K, McEnroe S, et al. Randomized trial comparing cyanoacrylate embolization and radiofrequency ablation for incompetent great saphenous veins (VeClose). J Vasc Surg. 2015;61:985-994.
- 10. Ogilvy CS, Stieg PE, Awad I, et al. AHA Scientific Statement: Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association. Stroke. 2001;32:1458-71.
- 11. Rosen RJ, Contractor S. The use of cyanoacrylate adhesives in the management of congenital vascular malformations. Semin Intervent Radiol. 2004;21:59-66.
- 12. Almeida JI, Javier JJ, Mackay E, et al. First human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. J Vasc Surg Venous Lymphat Disord. 2013;1:174-80.
- 13. Almeida JI, Javier JJ, Mackay EG, et al. Two-year follow-up of first human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. Phlebology. 2015;30:397-404.
- 14. Morrison N, Gibson K, Vasquez M, et al. Five-year extension study of patients from a randomized clinical trial (VeClose) comparing cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2020;8:978–989.
- 15. Park I. Successful use of VenaSeal system for the treatment of large great saphenous vein of 2.84-cm diameter. Ann Surg Treat Res. 2018;94(4):219-221.
- 16. Anwar MA, Lane TR, Davies AH, et al. Complications of radiofrequency ablation of varicose veins. Phlebology. 2012;27(Suppl):34-9.
- 17. Dexter D, Kabnick L, Berland T, et al. Complications of endovenous lasers. Phlebology. 2012;27(Suppl):40-5.
- 18. Park I, Jeong MH, Park CJ, et al. Clinical features and management of ‘Phlebitis-like abnormal reaction’ after cyanoacrylate closure for the treatment of incompetent saphenous veins. Ann Vasc Surg. 2019;55:239–45.
- 19. Park I. Initial outcomes of cyanoacrylate closure, Venaseal system, for the treatment of the incompetent great and small saphenous veins. Vasc Endovascular Surg. 2017;51:545-9.
- 20. Gibson K, Minjarez R, Rinehardt E, et al. Frequency and severity of hypersensitivity reactions in patients after Venaseal™ cyanoacrylate treatment of superficial venous insufficiency. Phlebology. 2019;35(5):337-344.
- 21. Lew PS, Tan YK, Chong TT, et al. VenasealTM Cyanoacrylate Glue Rejection Following Endovenous Ablation -Another New Complication. Biomed J Sci & Tech Res. 2019;17(4):12993-12994.
There are 21 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Cardiovascular Surgery |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | September 29, 2021 |
| Submission Date | June 15, 2021 |
| Published in Issue | Year 2021 |