Öz
Kaynakça
- 1. WHO Coronavirus (COVID-19) Dashboard https://covid19.who.int/ access date 10.04.2021
- 2. Batah SS and Fabro AT. Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians. Respir Med. 2021;176:106239. DOI: 10.1016/j.rmed.2020.106239.
- 3. van Eijk LE, Binkhorst M, Bourgonje AR, et al. COVID-19: immunopathology, pathophysiological mechanisms, and treatment options. J Pathol. 2021:10.1002/path.5642. DOI: 10.1002/path.5642.
- 4. Chen X, Liu K, Wang Z, et al. Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension. Int J Chron Obstruct Pulmon Dis. 2015;10:2525-33. DOI: 10.2147/COPD.S94211.
- 5. Truong QA, Massaro JM, Rogers IS, et al. Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study. Circ Cardiovasc Imaging. 2012;5:147-54. DOI:10.1161/CIRCIMAGING.111.968610
- 6. Bhalla V, Blish CA and South AM. A historical perspective on ACE2 in the COVID-19 era. J Hum Hypertens. 2020;1-5. DOI: 10.1038/s41371-020-00459-3
- 7. Tekcan Sanli DE, Yildirim D, Sanli AN, et al. Predictive value of CT imaging findings in COVID-19 pneumonia at the time of first-screen regarding the need for hospitalization or intensive care unit. Diagn Interv Radiol. 2020. DOI: 10.5152/dir.2020.20421.
- 8. Sanli DET, Yildirim D, Sanli AN, et al. A practical approach to imaging characteristics and standardized reporting of COVID-19: a radiologic review. Mil Med Res. 2021;8:7. DOI: 10.1186/s40779-021-00301-y.
- 9. Karmouty-Quintana H, Thandavarayan RA, Keller SP, et al. Emerging Mechanisms of Pulmonary Vasoconstriction in SARS-CoV-2-Induced Acute Respiratory Distress Syndrome (ARDS) and Potential Therapeutic Targets. Int J Mol Sci. 2020;21:8081. DOI: 10.3390/ijms21218081.
- 10. Santamarina MG, Boisier D, Contreras R, et al. COVID-19: a hypothesis regarding the ventilation-perfusion mismatch. Crit Care. 2020;24:395. DOI: 10.1186/s13054-020-03125-9.
- 11. Peluso L, Abella BS, Ferrer R, et al. Fever management in COVID-19 patients. Minerva Anestesiol. 2021;87:1-3. DOI: 10.23736/S0375-9393.20.15195-2.
- 12. Sanli DET, Altundag A, Kandemirli SG, et al. Relationship between disease severity and serum IL-6 levels in COVID-19 anosmia. Am J Otolaryngol. 2021;42:102796. DOI: 10.1016/j.amjoto.2020.102796.
- 13. Smilowitz NR, Kunichoff D, Garshick M, et al. C-reactive protein and clinical outcomes in patients with COVID-19. Eur Heart J. 2021:ehaa1103. DOI: 10.1093/eurheartj/ehaa1103.
- 14. Szarpak L, Ruetzler K, Safiejko K, et al. Lactate dehydrogenase level as a COVID-19 severity marker. Am J Emerg Med. 2020:S0735-6757(20)31034-2. DOI: 10.1016/j.ajem.2020.11.025.
- 15. Zhou Y, Ding N, Yang G, et al. Serum lactate dehydrogenase level may predict acute respiratory distress syndrome of patients with fever infected by SARS-CoV-2. Ann Transl Med. 2020;8:1118. DOI: 10.21037/atm-20-2411.
- 16. Henry BM, Aggarwal G, Wong J, et al. Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. Am J Emerg Med. 2020;38(9):1722-6. DOI: 10.1016/j.ajem.2020.05.073.
The Effect of Clinical, Laboratory Findings and Parenchymal Infiltration Features on the Diameter of the Main Pulmonary Artery in COVID-19 Pneumonia
Öz
Purpose: The main pulmonary artery diameter is an indirect indicator of pulmonary vascular bed resistance. In this study, it was aimed to reveal which parameters are associated with respiratory distress by evaluating the parameters affecting the diameter of the main pulmonary artery in cases with COVID-19 pneumonia.
Methods: The relationship between comorbid diseases, clinical findings, laboratory values, pulmonary infiltration features, and main pulmonary artery diameter (MPAD) was statistically evaluated.
Results: When MPAD 27.5 mm was considered as enlargement; it was significantly wider in smokers in COVID-19 pneumonia (p<0.05). It was statistically shown that there was not association with diabetes, hypertension, asthma, or COPD and MPAD (p>0.05). It was observed that MPAD was associated with shortness of breath (p=0.039; p<0.05) but not with cough and fever (p>0.05). Also, it was found that MPAD was significantly wider in cases with high CRP and LDH values (p=0.008; p<0.01, p=0.011; p<0.05, respectively). While MPAD did not differ significantly in those with ground-glass infiltration; MPAD was significantly larger in those with infiltration in the form of crazy-paving or consolidation (p<0.05). While there is no significant variation in MPAD in those with periferobasal involvement; MPAD was significantly wider in cases with central or mixed infiltration (p<0.05).
Conclusion: It is possible to indirectly predict respiratory distress in COVID-19 patients by measuring MPAD, which is associated with respiratory distress. Smoking, CRP and LDH values, central infiltration in the pattern of crazy-paving or consolidation are related with increased MPAD in COVID-19 pneumonia.
Anahtar Kelimeler
COVID-19 SARS-CoV-2 respiratory distress main pulmonary artery diameter chest CT crazy-paving ground-glass opacity
Kaynakça
- 1. WHO Coronavirus (COVID-19) Dashboard https://covid19.who.int/ access date 10.04.2021
- 2. Batah SS and Fabro AT. Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians. Respir Med. 2021;176:106239. DOI: 10.1016/j.rmed.2020.106239.
- 3. van Eijk LE, Binkhorst M, Bourgonje AR, et al. COVID-19: immunopathology, pathophysiological mechanisms, and treatment options. J Pathol. 2021:10.1002/path.5642. DOI: 10.1002/path.5642.
- 4. Chen X, Liu K, Wang Z, et al. Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension. Int J Chron Obstruct Pulmon Dis. 2015;10:2525-33. DOI: 10.2147/COPD.S94211.
- 5. Truong QA, Massaro JM, Rogers IS, et al. Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study. Circ Cardiovasc Imaging. 2012;5:147-54. DOI:10.1161/CIRCIMAGING.111.968610
- 6. Bhalla V, Blish CA and South AM. A historical perspective on ACE2 in the COVID-19 era. J Hum Hypertens. 2020;1-5. DOI: 10.1038/s41371-020-00459-3
- 7. Tekcan Sanli DE, Yildirim D, Sanli AN, et al. Predictive value of CT imaging findings in COVID-19 pneumonia at the time of first-screen regarding the need for hospitalization or intensive care unit. Diagn Interv Radiol. 2020. DOI: 10.5152/dir.2020.20421.
- 8. Sanli DET, Yildirim D, Sanli AN, et al. A practical approach to imaging characteristics and standardized reporting of COVID-19: a radiologic review. Mil Med Res. 2021;8:7. DOI: 10.1186/s40779-021-00301-y.
- 9. Karmouty-Quintana H, Thandavarayan RA, Keller SP, et al. Emerging Mechanisms of Pulmonary Vasoconstriction in SARS-CoV-2-Induced Acute Respiratory Distress Syndrome (ARDS) and Potential Therapeutic Targets. Int J Mol Sci. 2020;21:8081. DOI: 10.3390/ijms21218081.
- 10. Santamarina MG, Boisier D, Contreras R, et al. COVID-19: a hypothesis regarding the ventilation-perfusion mismatch. Crit Care. 2020;24:395. DOI: 10.1186/s13054-020-03125-9.
- 11. Peluso L, Abella BS, Ferrer R, et al. Fever management in COVID-19 patients. Minerva Anestesiol. 2021;87:1-3. DOI: 10.23736/S0375-9393.20.15195-2.
- 12. Sanli DET, Altundag A, Kandemirli SG, et al. Relationship between disease severity and serum IL-6 levels in COVID-19 anosmia. Am J Otolaryngol. 2021;42:102796. DOI: 10.1016/j.amjoto.2020.102796.
- 13. Smilowitz NR, Kunichoff D, Garshick M, et al. C-reactive protein and clinical outcomes in patients with COVID-19. Eur Heart J. 2021:ehaa1103. DOI: 10.1093/eurheartj/ehaa1103.
- 14. Szarpak L, Ruetzler K, Safiejko K, et al. Lactate dehydrogenase level as a COVID-19 severity marker. Am J Emerg Med. 2020:S0735-6757(20)31034-2. DOI: 10.1016/j.ajem.2020.11.025.
- 15. Zhou Y, Ding N, Yang G, et al. Serum lactate dehydrogenase level may predict acute respiratory distress syndrome of patients with fever infected by SARS-CoV-2. Ann Transl Med. 2020;8:1118. DOI: 10.21037/atm-20-2411.
- 16. Henry BM, Aggarwal G, Wong J, et al. Lactate dehydrogenase levels predict coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. Am J Emerg Med. 2020;38(9):1722-6. DOI: 10.1016/j.ajem.2020.05.073.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Araştırma Makaleleri |
| Yazarlar | |
| Yayımlanma Tarihi | 15 Mart 2022 |
| Gönderilme Tarihi | 1 Mayıs 2021 |
| Yayımlandığı Sayı | Yıl 2022Cilt: 13 Sayı: 2 |
