Araştırma Makalesi
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Yıl 2020, Cilt: 10 Sayı: 3, 396 - 401, 30.12.2020
https://doi.org/10.32448/entupdates.811534

Öz

Destekleyen Kurum

yok

Proje Numarası

Cukurova University Ethics Committee of the Institutional Review Board and Ethics Committee (Project no: 75/44).

Kaynakça

  • 1. Tophof MA, Hermanns A, Adelt T, et al. Side effects during subcutaneous immunotherapy in children with allergic diseases. Pediatr Allergy Immunol 2018;29:267-74.
  • 2. Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol 2007;120:25-85.
  • 3. Cox L, Nelson H, Lockey R, et al. Allergen immunotherapy: a practice parameter third update. J Allergy Clin Immunol 2011;127:1-55.
  • 4. Bernstein DI, Epstein TEG. Safety of allergen immunotherapy in North America from 2008-2017: Lessons learned from the ACAAI/AAAAI National Surveillance Study of adverse reactions to allergen immunotherapy. Allergy Asthma Proc 2020;41:108-11.
  • 5. Brożek JL, Bousquet J, Agache I, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision. J Allergy Clin Immunol 2017;140:950-8.
  • 6. Pedersen SE, Hurd SS, Lemanske RF Jr, et al. Global strategy for the diagnosis and management of asthma in children 5 years and younger. Pediatr Pulmonol 2011;46:1-17.
  • 7. Azkur D, Vezir E, Civelek E, et al. The frequency of large local and systemic reactions after subcutaneous immunotherapy in children. [Article in Turkish] Asthma Allergy Immunol 2013;11:37-42.
  • 8. Cox L, Larenas-Linnemann D, Lockey RF, Passalacqua G. Speaking the same language: The World Allergy Organization Subcutaneous Immunotherapy Systemic Reaction Grading System. J Allergy Clin Immunol 2010;125:569-74.
  • 9. Soyyiğit Ş, Sin BA. Asthma and Allergen Immunotherapy. [Article in Turkish] Güncel Göğüs Hastalıkları Serisi 2015;3:200-7.
  • 10. Epstein TG, Liss GM, Murphy-Berendts K, Bernstein DI. Immediate and delayed-onset systemic reactions after subcutaneous immunotherapy injections: ACAAI/AAAAI surveillance study of subcutaneous immunotherapy: year 2. Ann Allergy Asthma Immunol 2011;107:426-31.
  • 11. Pfaar O, Bachert C, Bufe A, et al. Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases. Allergo J Int 2014;23:282-319.
  • 12. Çekiç Ş, Sapan N. Allergen Specific Immunotherapy. [Article in Turkish] J Curr Pediatr 2015;13:46-55.
  • 13. Gür Çetinkaya P, Esenboğa S, Uysal Soyer Ö, Tuncer A, Şekerel BE, Şahiner ÜM. Subcutaneous venom immunotherapy in children: Efficacy and safety. Ann Allergy Asthma Immunol 2018;120:424-8.
  • 14. Adamic K, Zidarn M, Bajrovic N, Erzen R, Kopac P, Music E. The local and systemic side-effects of venom and inhaled-allergen subcutaneous immunotherapy. Wien Klin Wochenschr 2009;121:357-60.
  • 15. La Shell MS, Calabria CW, Quinn JM. Imported fire ant field reaction and immunotherapy safety characteristics: the IFACS study. J Allergy Clin Immunol 2010;125:1294-9.
  • 16. Calabria CW, Coop CA, Tankersley MS. The LOCAL Study: Local reactions do not predict local reactions in allergen immunotherapy. J Allergy Clin Immunol 2009;124:739-44.
  • 17. Businco L, Zannino L, Cantani A, Corrias A, Fiocchi A, La Rosa M. Systemic reactions to specific immunotherapy in children with respiratory allergy: a prospective study. Pediatr Allergy Immunol 1995;6:44-7.
  • 18. Can D, Demir E, Tanaç R, Gülen F, Yenigün A. Immediate adverse reactions to immunotherapy. J Investig Allergol Clin Immunol 2003;13:177-80.
  • 19. Şenbaba E, Çatal F, Topal E, Ermiştekin H, Yıldırım N, Sinanoğlu MS. Delayed severe systemic reaction (anaphylaxis) after subcutaneous immunotherapy injections: case report. [Article in Turkish] Asthma Allergy Immunol 2013;11:204-7.
  • 20. Rank MA, Oslie CL, Krogman JL, Park MA, Li JT. Allergen immunotherapy safety: characterizing systemic reactions and identifying risk factors. Allergy Asthma Proc 2008;29:400-5.
  • 21. Bernstein DI, Epstein T. Systemic reactions to subcutaneous allergen immunotherapy. Immunol Allergy Clin North Am 2011;31:241-9.

Frequency of adverse reactions after subcutaneous allergen immunotherapy in children

Yıl 2020, Cilt: 10 Sayı: 3, 396 - 401, 30.12.2020
https://doi.org/10.32448/entupdates.811534

Öz

Objective: Subcutaneous allergen immunotherapy (SCIT) is an effective treatment method for allergic rhinitis, asthma and venom allergy. The aim of this study was to evaluate the frequency of adverse reactions in children undergoing SCIT.
Methods: This retrospective study included patients that underwent SCIT in our clinic for a period of five years due to a diagnosis of Apis mellifera venom allergy or allergic asthma and/or rhinitis. 303 patients were divided into groups based on the form of SCIT administered and the presence of injection-related reactions.
Results: Mean age at the initiation of SCIT was 10 (range, 5-18) years old. SCIT for aeroallergens was administered to 289 (95.4%) patients and SCIT for venom to 14 (4.6%) patients. Local reactions were observed in 54 (17.8%) and systemic reactions developed in 4 (1.3%) patients. The local reactions mostly occurred after SCIT with Apis mellifera venom (100%), followed by house dust mite (20.6%), mold (16.7%) and grass pollen (16.7%).
Conclusion: Although SCIT is a safe treatment method used for allergic diseases, it must be administered only in centers with appropriate emergency equipment due to the risk of side effects.

Proje Numarası

Cukurova University Ethics Committee of the Institutional Review Board and Ethics Committee (Project no: 75/44).

Kaynakça

  • 1. Tophof MA, Hermanns A, Adelt T, et al. Side effects during subcutaneous immunotherapy in children with allergic diseases. Pediatr Allergy Immunol 2018;29:267-74.
  • 2. Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol 2007;120:25-85.
  • 3. Cox L, Nelson H, Lockey R, et al. Allergen immunotherapy: a practice parameter third update. J Allergy Clin Immunol 2011;127:1-55.
  • 4. Bernstein DI, Epstein TEG. Safety of allergen immunotherapy in North America from 2008-2017: Lessons learned from the ACAAI/AAAAI National Surveillance Study of adverse reactions to allergen immunotherapy. Allergy Asthma Proc 2020;41:108-11.
  • 5. Brożek JL, Bousquet J, Agache I, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision. J Allergy Clin Immunol 2017;140:950-8.
  • 6. Pedersen SE, Hurd SS, Lemanske RF Jr, et al. Global strategy for the diagnosis and management of asthma in children 5 years and younger. Pediatr Pulmonol 2011;46:1-17.
  • 7. Azkur D, Vezir E, Civelek E, et al. The frequency of large local and systemic reactions after subcutaneous immunotherapy in children. [Article in Turkish] Asthma Allergy Immunol 2013;11:37-42.
  • 8. Cox L, Larenas-Linnemann D, Lockey RF, Passalacqua G. Speaking the same language: The World Allergy Organization Subcutaneous Immunotherapy Systemic Reaction Grading System. J Allergy Clin Immunol 2010;125:569-74.
  • 9. Soyyiğit Ş, Sin BA. Asthma and Allergen Immunotherapy. [Article in Turkish] Güncel Göğüs Hastalıkları Serisi 2015;3:200-7.
  • 10. Epstein TG, Liss GM, Murphy-Berendts K, Bernstein DI. Immediate and delayed-onset systemic reactions after subcutaneous immunotherapy injections: ACAAI/AAAAI surveillance study of subcutaneous immunotherapy: year 2. Ann Allergy Asthma Immunol 2011;107:426-31.
  • 11. Pfaar O, Bachert C, Bufe A, et al. Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases. Allergo J Int 2014;23:282-319.
  • 12. Çekiç Ş, Sapan N. Allergen Specific Immunotherapy. [Article in Turkish] J Curr Pediatr 2015;13:46-55.
  • 13. Gür Çetinkaya P, Esenboğa S, Uysal Soyer Ö, Tuncer A, Şekerel BE, Şahiner ÜM. Subcutaneous venom immunotherapy in children: Efficacy and safety. Ann Allergy Asthma Immunol 2018;120:424-8.
  • 14. Adamic K, Zidarn M, Bajrovic N, Erzen R, Kopac P, Music E. The local and systemic side-effects of venom and inhaled-allergen subcutaneous immunotherapy. Wien Klin Wochenschr 2009;121:357-60.
  • 15. La Shell MS, Calabria CW, Quinn JM. Imported fire ant field reaction and immunotherapy safety characteristics: the IFACS study. J Allergy Clin Immunol 2010;125:1294-9.
  • 16. Calabria CW, Coop CA, Tankersley MS. The LOCAL Study: Local reactions do not predict local reactions in allergen immunotherapy. J Allergy Clin Immunol 2009;124:739-44.
  • 17. Businco L, Zannino L, Cantani A, Corrias A, Fiocchi A, La Rosa M. Systemic reactions to specific immunotherapy in children with respiratory allergy: a prospective study. Pediatr Allergy Immunol 1995;6:44-7.
  • 18. Can D, Demir E, Tanaç R, Gülen F, Yenigün A. Immediate adverse reactions to immunotherapy. J Investig Allergol Clin Immunol 2003;13:177-80.
  • 19. Şenbaba E, Çatal F, Topal E, Ermiştekin H, Yıldırım N, Sinanoğlu MS. Delayed severe systemic reaction (anaphylaxis) after subcutaneous immunotherapy injections: case report. [Article in Turkish] Asthma Allergy Immunol 2013;11:204-7.
  • 20. Rank MA, Oslie CL, Krogman JL, Park MA, Li JT. Allergen immunotherapy safety: characterizing systemic reactions and identifying risk factors. Allergy Asthma Proc 2008;29:400-5.
  • 21. Bernstein DI, Epstein T. Systemic reactions to subcutaneous allergen immunotherapy. Immunol Allergy Clin North Am 2011;31:241-9.
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kulak Burun Boğaz
Bölüm Makaleler
Yazarlar

Ayşe Şenay Şaşihüseyinoğlu 0000-0003-4085-0256

Dilek Doğruel Bu kişi benim 0000-0003-3972-7277

Derya Altintas 0000-0003-2090-5248

Proje Numarası Cukurova University Ethics Committee of the Institutional Review Board and Ethics Committee (Project no: 75/44).
Yayımlanma Tarihi 30 Aralık 2020
Gönderilme Tarihi 16 Ekim 2020
Kabul Tarihi 28 Kasım 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 10 Sayı: 3

Kaynak Göster

APA Şaşihüseyinoğlu, A. Ş., Doğruel, D., & Altintas, D. (2020). Frequency of adverse reactions after subcutaneous allergen immunotherapy in children. ENT Updates, 10(3), 396-401. https://doi.org/10.32448/entupdates.811534
AMA Şaşihüseyinoğlu AŞ, Doğruel D, Altintas D. Frequency of adverse reactions after subcutaneous allergen immunotherapy in children. ENT Updates. Aralık 2020;10(3):396-401. doi:10.32448/entupdates.811534
Chicago Şaşihüseyinoğlu, Ayşe Şenay, Dilek Doğruel, ve Derya Altintas. “Frequency of Adverse Reactions After Subcutaneous Allergen Immunotherapy in Children”. ENT Updates 10, sy. 3 (Aralık 2020): 396-401. https://doi.org/10.32448/entupdates.811534.
EndNote Şaşihüseyinoğlu AŞ, Doğruel D, Altintas D (01 Aralık 2020) Frequency of adverse reactions after subcutaneous allergen immunotherapy in children. ENT Updates 10 3 396–401.
IEEE A. Ş. Şaşihüseyinoğlu, D. Doğruel, ve D. Altintas, “Frequency of adverse reactions after subcutaneous allergen immunotherapy in children”, ENT Updates, c. 10, sy. 3, ss. 396–401, 2020, doi: 10.32448/entupdates.811534.
ISNAD Şaşihüseyinoğlu, Ayşe Şenay vd. “Frequency of Adverse Reactions After Subcutaneous Allergen Immunotherapy in Children”. ENT Updates 10/3 (Aralık 2020), 396-401. https://doi.org/10.32448/entupdates.811534.
JAMA Şaşihüseyinoğlu AŞ, Doğruel D, Altintas D. Frequency of adverse reactions after subcutaneous allergen immunotherapy in children. ENT Updates. 2020;10:396–401.
MLA Şaşihüseyinoğlu, Ayşe Şenay vd. “Frequency of Adverse Reactions After Subcutaneous Allergen Immunotherapy in Children”. ENT Updates, c. 10, sy. 3, 2020, ss. 396-01, doi:10.32448/entupdates.811534.
Vancouver Şaşihüseyinoğlu AŞ, Doğruel D, Altintas D. Frequency of adverse reactions after subcutaneous allergen immunotherapy in children. ENT Updates. 2020;10(3):396-401.