Öz
The presented case is a 52-year-old woman diagnosed with a glucocorticoid and probably aldosterone- secreting adrenocortical carcinoma during the investigation for hypokalemic paralysis. Adrenal cancers are very rare tumors and their prognosis is very poor. Presentation with heavy hypokalemia is extremely rare. The patient is reported in order to draw attention to the endocrinological diseases which should be screened in individuals with hypokalemia as well as being a rare case
Anahtar Kelimeler
Kaynakça
- Ahlawat SK, Sachdev. Hypokalaemic paralysis. Postgrad Med 1999;75:193-7.
- Stewart PM. Adrenal cortex and endocrine hypertension. In Williams Textbook of Endocrinology. Kronenberg HM, Melmed S, Polonsky KS and Larsen PR Eds. 11th ed, Canada, Saunders Elsevier 2008, pp.445-503.
- Kurtulmus N, Yarman S, Azizlerli H, Kapran Y. Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. Horm Res. 2004;62:67-70.
- Beom SH, Lee KW, Yang Y, Choi Y, Song KH, Kim YJ, et al. Metastatic adrenocortical carcinoma presenting simultaneously with Cushing’s and Conn’s syndromes: a case report. Jpn J Clin Oncol 2011;41:1287-91.
- Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, et al; Endocrine Society. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2008;93:3266-81.
- Yamakita N, Murai T, Miyamoto K, Matsunami H, Ikeda T, Sasano H, et al. Variant of pre-clinical Cushing’s syndrome: hypertension and hypokalemia associated with normoreninemic normoaldosteronism. Hypertens Res. 2002;25:623-30.
- Baba T, Aoyagi K, Murabayashi S, Sasaki K, Nigawara K, Takebe K. Renin-angiotensin system and plasma aldosterone in Cushing’s syndrome. Endocrinol Jpn. 1983;30:715-21.
Öz
Sunulan olgu, hipokalemik paralizi nedeni ile araştırılırken glukokortikoid ve muhtemelen aldosteron- salgılayan adrenokortikal kanser tespit edilen 52 yaşında kadın hastadır. Adrenal kanserler çok nadir tümörlerdir ve prognozları oldukça kötüdür. Hastalığın ağır hipopotasemi ile ortaya çıkması ise daha da seyrek görülen bir durumdur. Hasta, nadir bir olgu olmasının yanı sıra hipopotasemi saptanan bir kişide araştırılması gereken endokrinolojik problemlere dikkat çekmek amacı ile sunulmuştur
Anahtar Kelimeler
Kaynakça
- Ahlawat SK, Sachdev. Hypokalaemic paralysis. Postgrad Med 1999;75:193-7.
- Stewart PM. Adrenal cortex and endocrine hypertension. In Williams Textbook of Endocrinology. Kronenberg HM, Melmed S, Polonsky KS and Larsen PR Eds. 11th ed, Canada, Saunders Elsevier 2008, pp.445-503.
- Kurtulmus N, Yarman S, Azizlerli H, Kapran Y. Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. Horm Res. 2004;62:67-70.
- Beom SH, Lee KW, Yang Y, Choi Y, Song KH, Kim YJ, et al. Metastatic adrenocortical carcinoma presenting simultaneously with Cushing’s and Conn’s syndromes: a case report. Jpn J Clin Oncol 2011;41:1287-91.
- Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, et al; Endocrine Society. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2008;93:3266-81.
- Yamakita N, Murai T, Miyamoto K, Matsunami H, Ikeda T, Sasano H, et al. Variant of pre-clinical Cushing’s syndrome: hypertension and hypokalemia associated with normoreninemic normoaldosteronism. Hypertens Res. 2002;25:623-30.
- Baba T, Aoyagi K, Murabayashi S, Sasaki K, Nigawara K, Takebe K. Renin-angiotensin system and plasma aldosterone in Cushing’s syndrome. Endocrinol Jpn. 1983;30:715-21.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Case Report |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Mart 2013 |
| Yayımlandığı Sayı | Yıl 2013Sayı: 1 |