Öz
Hypothyroidism often leads to anemia due to various mechanisms. Even though newborns with congenital hypothyroidism CH may seem to be normal after birth, severe abnormalities such as mental and physical growth retardation, and speech and gait disorders occur over time. Although anemia may occur in CH, the disease is diagnosed earlier due to severe signs and symptoms. We present an undiagnosed adulthood case who has typical symptoms and signs of CH that has came to us with the complaint of profound anemia. The patient was diagnosed as CH with iron deficiency anemia
Anahtar Kelimeler
Kaynakça
- Roberts CG, Ladenson PW. Hypothyroidism. Lancet 2004;363(9411):793-803.
- Mehmet E, Aybike K, Ganidagli S, Mustafa K. Characteristics of anemia in subclinical and overt hypothyroid patients. Endocr J 2012;59(3):213-220.
- Antonijević N, Nesović M, Trbojević B, Milosević R. Anemia in hypothyroidism. Med Pregl 1999;52(3-5): 136-140.
- Horton L CR, England JM. The haematology of hypothyroidism. Quarterly Journal of Medicine New Series 1976;45:101-124.
- Fein HG, Rivlin RS. Anemia in thyroid diseases. Med Clin North Am 1975;59(5):1133-1145.
- Rastogi MV, LaFranchi SH. Congenital hypothyroidism. Orphanet J Rare Dis 2010;5:17.
- Cinaz P. Konjenital Hipotiroidi. Klinik Pediatri 2003;2(2):59-63.
- Ataş A, Çakmak A, Karazeybek H. Konjenital Hipotiroidizm. Güncel Pediatri 2007;5: 70-6.
- MacGillivray M. Congenital Hypothyroidism: Pediatric Endocrinology 1st edition. Philadelphia: Lipincott Williams and Wilkins, 2004: 490-507.
- Tarim OF, Yordam N. Congenital hypothyroidism in Turkey: a retrospective evaluation of 1000 cases. Turk J Pediatr 1992;34:197-202.
- http://sbu.saglik.gov.tr/sb/default.asp?sayfa=birimler&cid=4.
- Kazemi-Jahromi M, Shahriari-Ahmadi A, Samedanifard S
- Doostmohamadian S, Abdolahpoor E, Allameh SF. The Association Between Hypothyroidism and Anemia: a Clinical Study. International Journal of Hematology-Oncology and Stem Cell Research 2010;4:6-9
- Lippi G, Montagnana M, Targher G, Salvagno GL, Guidi GC. Prevalence of folic Acid and vitamin B12 deficiencies in patients with thyroid disorders. Am J Med Sci 2008;336(1):50-52.
- Vescovi PP, Favaloro EJ, Lippi G, Garofano M, Montagnana M, Manzato F, Franchini M. The spectrum of coagulation abnormalities in thyroid disorders. Semin Thromb Hemost 201;37(1):7-10.
Öz
Hipotiroidizm çeşitli mekanizmalarla sıklıkla anemiye yol açmaktadır. Konjenital hipotiroidi KH olan bebekler doğum sonrasında normal gözükseler de, zaman ilerledikçe mental ve fiziksel gelişme geriliği, konuşma ve yürüme bozuklukları gibi ciddi anormallikler meydana gelir. KH ile anemi oluşabilmekle birlikte hastalar genellikle daha erken dönemde ortaya çıkan ciddi semptom ve bulgular nedeniyle tanı alırlar. Erişkin yaşa ulaşmasına rağmen tanı almamış, KH’nin tipik semptom ve bulgularına sahip olan ve derin anemiye bağlı şikayetlerle tarafımıza başvurup KH + demir eksikliği anemisi tanısı koyduğumuz bir olgumuzu sunuyoruz
Anahtar Kelimeler
Kaynakça
- Roberts CG, Ladenson PW. Hypothyroidism. Lancet 2004;363(9411):793-803.
- Mehmet E, Aybike K, Ganidagli S, Mustafa K. Characteristics of anemia in subclinical and overt hypothyroid patients. Endocr J 2012;59(3):213-220.
- Antonijević N, Nesović M, Trbojević B, Milosević R. Anemia in hypothyroidism. Med Pregl 1999;52(3-5): 136-140.
- Horton L CR, England JM. The haematology of hypothyroidism. Quarterly Journal of Medicine New Series 1976;45:101-124.
- Fein HG, Rivlin RS. Anemia in thyroid diseases. Med Clin North Am 1975;59(5):1133-1145.
- Rastogi MV, LaFranchi SH. Congenital hypothyroidism. Orphanet J Rare Dis 2010;5:17.
- Cinaz P. Konjenital Hipotiroidi. Klinik Pediatri 2003;2(2):59-63.
- Ataş A, Çakmak A, Karazeybek H. Konjenital Hipotiroidizm. Güncel Pediatri 2007;5: 70-6.
- MacGillivray M. Congenital Hypothyroidism: Pediatric Endocrinology 1st edition. Philadelphia: Lipincott Williams and Wilkins, 2004: 490-507.
- Tarim OF, Yordam N. Congenital hypothyroidism in Turkey: a retrospective evaluation of 1000 cases. Turk J Pediatr 1992;34:197-202.
- http://sbu.saglik.gov.tr/sb/default.asp?sayfa=birimler&cid=4.
- Kazemi-Jahromi M, Shahriari-Ahmadi A, Samedanifard S
- Doostmohamadian S, Abdolahpoor E, Allameh SF. The Association Between Hypothyroidism and Anemia: a Clinical Study. International Journal of Hematology-Oncology and Stem Cell Research 2010;4:6-9
- Lippi G, Montagnana M, Targher G, Salvagno GL, Guidi GC. Prevalence of folic Acid and vitamin B12 deficiencies in patients with thyroid disorders. Am J Med Sci 2008;336(1):50-52.
- Vescovi PP, Favaloro EJ, Lippi G, Garofano M, Montagnana M, Manzato F, Franchini M. The spectrum of coagulation abnormalities in thyroid disorders. Semin Thromb Hemost 201;37(1):7-10.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Case Report |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Haziran 2013 |
| Yayımlandığı Sayı | Yıl 2013Sayı: 2 |