Abstract
Tuberculosis is an infectious disease which is common is common in developing countries. Approximately 5 to 10% of cases of tuberculosis are involved in the brain and nervous system. Central Nervous System CNS involvement may occur as meningitis, abscess, solitary tuberculoma, infarction, or miliary parenchymal disease. Tuberculoma is very rare. 50 years old male patient suffered from dizziness and, gait impairment. This patient was operated. Pathologic examination revealed necrotizing granulomatous inflammation. Tuberculoma should be taken into consideration as a possible diagnosis in such cases
References
- Gropper MR, Schulder M, Duran HL, Wolansky L. Cerebral tuberculosis with expansion into brainstem tuberculoma. Report of two cases. J Neurosurg 1994;81:927–931.
- Talamas O, Del Brutto OH, Garcia-Ramos G. Brain-stem tuberculoma. An analysis of 11 patients. Arch Neurol 1989;46:529–535.
- Menon V, Gogoi M, Saxena R, Singh S, Kumar A. Isolated ‘‘one and a half syndrome’’ with brainstem tuberculoma. Indian J Pediatr 2004;71:469–471.
- Sonmez G, Ozturk E, Sildiroglu HO, Mutlu H, Cuce F, Senol MG, Kutlu A, Basekim CC, Kizilkaya E. MRI findings of intracranial tuberculomas. Clin Imaging 2008;32:88-92.
- Solbrig MV, Healy JF, Jay CA. Infections of the Nervous System: In Bradley WG, Daroff RB, Marsden CD, Fenichel GM (editors). Neurology in Clinical Practice, Third Edition, Boston:Butterworth- Heinemann, 2000,1329-1332.
- Talamas O, Del Brutto OH, Garcia-Ramos G. Brain-stem tuberculoma. An analysis of 11 patients. Arch Neurol 1989;46:529–535.
- Özge A, Misirli H, Erenoğlu NY. Serebral Tüberküloma. Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi 1998;11:58-61.
- Elde FF, Gean AD, So YT. Clinical and radiographic findings in disseminated tuberculosis of the brain. Neurology 1993;43:1427-1429.
- Arseni C, Samtica DC. Intraspinal tuberculous granuloma. Brain 1960;83:285-292.
- Bucy PC, Oberhill HR. Intradural spinal granulomas. J Neurosurg 1950;7:1-12.
- B. Whiteman M, Espinoza L, Post MJD et al. Central nervous system tuberculosis in HIV-infected patients: Clinical and radiographic findings. Am J Neuroradiol 1995;6:1319-1327.
- Garg RK. Tuberculosis of the Central Nervous System. Postgrad Med J 1999;75:133-140.
- Dastur HM, Shah MD. Intramedullary tuberculoma of the spinal cord. Indian Paediatrics 1968;5:468-471.
- Citow JS, Ammirati M. Intramedullary tuberculoma of the spinal cord: Case report. Neurosurgery 1994;35:327-330.
- Castro CC, Barros NG, Campos ZM et al. CT scans of cranial tuberculosis. Radiol Clin North Am 1995;33:753-769.
- Huang CR, Lui CC, Chang WN et al. Neuroimages of disseminated neurotuberculosis. Report of one case. Clinical Imaging 1999;23:218-222.
- Misra UK, Kalita J, Roy AK et al. Role of clinical, radiological, and neurophysiological changes in predicting the outcome of tuberculous meningitis: A multivariable analysis. J Neurol Neurosurg Psychiatry 2000;68:300-303.
- Thwaites G, Chau TTH, Mai NTH et al. Tuberculosis meningitis. J Neurol Neurosurg Psychiatry 2000;68:289-299.
- Tan EK, Chee MWL, Chan LL, Lee YL. Culture positive tuberculous meningitis: Clinical indicators of poor prognosis. Clin Neurol Neurosurg 1999;101:157-160.
Abstract
Mycobacterium tüberculosisin neden olduğu bir enfeksiyon hastalığı olan tüberküloz, gelişmekte olan ülkelerde sık görülmektedir. Tüberküloz vakalarının yaklaşık %5-10’unda beyin ve sinir sistemi tutulumu görülür. Merkezi Sinir Sistemi MSS tutulumu menenjit, abse, soliter tüberkülom, infarkt veya milier parankimal hastalık olarak ortaya çıkabilir. Santral sinir sistemi tutulumunda en az tuberkülomlar gözlenir ve bunlar beyin parankimindeki tüberkülom granülasyonlarıdır ve kitle etkisiyle klinik oluşturabilirler. 50 yaşında erkek olgu, son bir aydır giderek artan baş dönmesi, yürümede bozulma şikayetleri ile kliniğimize başvurdu. Yapılan tetkikleri sonucunda serebellar kitleler saptanan olgu opere edildi. Patoloji sonucu, nekrotizan granülomatöz iltihap olarak değerlendirildi. Klinik olarak serebellar metastaz olarak düşünülen; fakat anamnez ve radyolojisi derinleştirildiğinde tüberküloz lehine değerlendirilen olgu¸ tüberkülozun nadir görülen tipi olan tüberküloma örnek olarak sunulmuştur
References
- Gropper MR, Schulder M, Duran HL, Wolansky L. Cerebral tuberculosis with expansion into brainstem tuberculoma. Report of two cases. J Neurosurg 1994;81:927–931.
- Talamas O, Del Brutto OH, Garcia-Ramos G. Brain-stem tuberculoma. An analysis of 11 patients. Arch Neurol 1989;46:529–535.
- Menon V, Gogoi M, Saxena R, Singh S, Kumar A. Isolated ‘‘one and a half syndrome’’ with brainstem tuberculoma. Indian J Pediatr 2004;71:469–471.
- Sonmez G, Ozturk E, Sildiroglu HO, Mutlu H, Cuce F, Senol MG, Kutlu A, Basekim CC, Kizilkaya E. MRI findings of intracranial tuberculomas. Clin Imaging 2008;32:88-92.
- Solbrig MV, Healy JF, Jay CA. Infections of the Nervous System: In Bradley WG, Daroff RB, Marsden CD, Fenichel GM (editors). Neurology in Clinical Practice, Third Edition, Boston:Butterworth- Heinemann, 2000,1329-1332.
- Talamas O, Del Brutto OH, Garcia-Ramos G. Brain-stem tuberculoma. An analysis of 11 patients. Arch Neurol 1989;46:529–535.
- Özge A, Misirli H, Erenoğlu NY. Serebral Tüberküloma. Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi 1998;11:58-61.
- Elde FF, Gean AD, So YT. Clinical and radiographic findings in disseminated tuberculosis of the brain. Neurology 1993;43:1427-1429.
- Arseni C, Samtica DC. Intraspinal tuberculous granuloma. Brain 1960;83:285-292.
- Bucy PC, Oberhill HR. Intradural spinal granulomas. J Neurosurg 1950;7:1-12.
- B. Whiteman M, Espinoza L, Post MJD et al. Central nervous system tuberculosis in HIV-infected patients: Clinical and radiographic findings. Am J Neuroradiol 1995;6:1319-1327.
- Garg RK. Tuberculosis of the Central Nervous System. Postgrad Med J 1999;75:133-140.
- Dastur HM, Shah MD. Intramedullary tuberculoma of the spinal cord. Indian Paediatrics 1968;5:468-471.
- Citow JS, Ammirati M. Intramedullary tuberculoma of the spinal cord: Case report. Neurosurgery 1994;35:327-330.
- Castro CC, Barros NG, Campos ZM et al. CT scans of cranial tuberculosis. Radiol Clin North Am 1995;33:753-769.
- Huang CR, Lui CC, Chang WN et al. Neuroimages of disseminated neurotuberculosis. Report of one case. Clinical Imaging 1999;23:218-222.
- Misra UK, Kalita J, Roy AK et al. Role of clinical, radiological, and neurophysiological changes in predicting the outcome of tuberculous meningitis: A multivariable analysis. J Neurol Neurosurg Psychiatry 2000;68:300-303.
- Thwaites G, Chau TTH, Mai NTH et al. Tuberculosis meningitis. J Neurol Neurosurg Psychiatry 2000;68:289-299.
- Tan EK, Chee MWL, Chan LL, Lee YL. Culture positive tuberculous meningitis: Clinical indicators of poor prognosis. Clin Neurol Neurosurg 1999;101:157-160.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | December 1, 2013 |
| Published in Issue | Year 2013Issue: 4 |