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The Importance of Infant Nutrition For Preventing Celiac Disease

Year 2014, Issue: 1, 15 - 19, 01.03.2014

Nevin Şanlıer Sabriye Bolluk

Abstract

Celiac disease CD is a multifactorial problem caused by gluten and prola- mins, genetic and environmental factors in genetically susceptible individu- als. In recent years, studies are focused in the early complementary feeding and time of gluten introduction and amount on the development of CD. Al- thoughi some studies have shown a protective effect of breast milk against the development of CD. This has not been confirmed by other studies. Due to the lack of studies showing that breastfeeding would prevent CD in long term; the effect of breastmilk to prevent or delay the development of clini- cal manifestations remains a controversial issue. European Pediatric Gastro- enterology, Hepatology and Nutrition Association ESPGHAN suggests that time of gluten introduction should not be early < 4 months and late >7 months and, when gluten introduction to diet breast milk should continue. With the completion of ongoing trials in the future more detailed informa- tion in this regard will be obtained and the recommendations regarding the introduction time and the amound of gluten in infant diet will be revised over time. In this review, studies related with breast milk and gluten intake in infant nutrition in the prevention of celiac disease are discussed

Keywords

celiac disease infant nutrition breast milk

References

  • Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. Journal of Pediatric Gastroenterology and Nutrition. 2012;54(1):136-160.
  • Jabri B, Kasarda DD, Green PH. Innate and adaptive immunity: the yin and yang of celiac disease. Immunological Reviews 2005;206(1):219-231.
  • Dalgıç B, Sarı S, Özcan B, Baştürk B, Ensari A, Eğritaş Ö, et al. Türk çocuklarında çölyak hastalığı ile ilişkili olası etmen ve belirtilerin değerlendirilmesi. Turk Arch Ped 2011;46:323-330.
  • Göral V, Yıldırım N, Kaplan A, Şit D, Çelik M. The frequency of gluten enteropathy disease. Akademik Gastroenteroloji Dergisi 2007;6(3):144-148.
  • Silano M. Effect of the timing of gluten introduction on the development of celiac disease. World Journal of Gastroenterology 2010;16(16):1939.
  • Doğdu G, Duru NS, Elevli M, Çivilibal M. Tip 1 Diyabetes Mellituslu Çocuklarda Tiroid Otoimmünitesi ve Gluten Duyarlı Enteropati. Haseki Tıp Bülteni 2012;50:39-42.
  • Troncone R, Ivarsson A, Szajewska H, Mearin ML, Members of European Multistakeholder Platform on CD. Review article: future research on coeliac disease - a position report from the European multistakeholder platform on coeliac disease (CDEUSSA). Aliment Pharmacol Ther 2008;27(11):1030-1043.
  • Hogen Esch CE, Rosen A, Auricchio R, Romanos J, Chmielewska A, Putter H, et al. The PreventCD Study design: towards new strategies for the prevention of coeliac disease. European Journal of Gastroenterology & Hepatology 2010;22(12):1424-1430.
  • Samur G. Anne Sütü. TC Sağlık Bakanlığı Temel S ağlık Hizmetleri Genel Müdürlüğü Beslenme ve Fiziksel Aktiviteler Daire Başkanlığı Yay., Klasmat Mat., Ankara. 2008. http://www.seah.gov.tr/pdf/anne_sutu. pdf Erişim tarihi: 15.11.2013
  • Köksal G, Özel HG. Bebek beslenmesi. Sağlık Bakanlığı Yayın. 2008(726). http://www.beslenme.go v.tr/content/files/arastirmalar/ uyelik/beslenme_bilgi_serisi/Kitaplar/a/a_08_bebek_beslenmesi. pdf Erişim tarihi: 15.11.2013
  • Kalkanoğlu HS. Ç ocukluk Çağı Beslenmesinin İleri Yaşama Etkisi. http://www.danoneenstitusu.org.tr/news.php?id=124&cat=9 Erişim tarihi: 15.11.2013
  • Nash S. Does exclusive breast-feeding reduce the risk of coeliac disease in children? British Journal of Community Nursing 2003;8(3):127-132.
  • Peters U, Schneeweiss S, Trautweina EA, Erbersdoblera HF. A Case- Control Study of the Effect o f Infant Feeding on Celiac Disease. Annals of Nutrition & Metabolism 2001;45:135–142.
  • Decker E, Engelmann G, Findeisen A, Gerner P, Laaβ M, Ney D et al. Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. Pediatrics 2010;125(6):e1433-1440.
  • Roberts SE, Williams JG, Meddings D, Davidson R, Goldacre MJ. Perinatal risk factors and coeliac disease in children and young adults: a record linkage study. Aliment Pharmacol Ther 2009;29(2):222-231.
  • Akobeng AK, Ramanan AV, Buchan I, Heller RF. Effect of breast feeding on risk of coeliac disease: a systematic revi ew and meta- analysis of observational studies. Archives of Disease in Childhood 2006;91(1):39-43.
  • Ascher H, Krantz I, Rydberg L, Nordin P, Kristiansson B. Influence of infant feeding and gluten intake on coeliac disease. Archives of Disease i n Childhood 1997;76:113-117.
  • Auricchio S, Follo D, de Ritis G, Giunta A, Marzorati D, Prampolini L, et al. Does breast feeding protect against the development of clinical symptoms of celiac disease in children? Journal of Pediatric Gastroenterology and Nutrition 1983;2(3):428-433.
  • Greco L, Auricchio S, Mayer M, Grimaldi M. Case control study on nutritional risk factors in celiac disease. Journal of Pediatric Gastroenterology and Nutrition 1998;7(3 ):395-399.
  • Ivarsson A, Hernell O, Stenlund H, Persson LÅ. Breast-feeding protects against celiac disease. Am J Clin Nutr 2002;75:914–921.
  • Norris JM, Barriga K, Hoffenberg EJ, et al. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA : the Journal of the American Medical Association. May 18 2005;293(19):2343-2351.
  • Welander A, Tjernberg AR, Montgomery SM, Ludvigsson J, Ludvigsson JF. Infectious disease and risk of later celiac disease in childhood. Pediatrics. Mar 2010;125(3):e530-536.
  • Ziegler AG, Schmid S, Huber D, Hummel M, Bonifacio E. Early Infant Feeding and Risk of Developing Type 1 Diabetes–Associated Autoantibodies. JAMA : the journal of the American Medical Association 2003;290:1721-1728.
  • Fälth‐Magnusson K, Franzen L, Jansson G, Laurin P, Stenhammai L. Infant feeding history shows distinct differences between Swedish celiac and reference children. Pediatric allergy and immunology 1996;7(1):1-5.
  • M itt K, Uibo O. Low cereal intake in Estonian infants: the possible explanation for the low frequency of coeliac disease in Estonia. European journal of clinical nutrition 1998;52(2):85.
  • A kobeng AK, Heller RF. Assessing the population impact of low rates of breast feeding on asthma, coeliac disease and obesity: the use of a new statistical method. Archives of Disease in Childhood 2007;92(6):483-485.
  • P ersson L, Ivarsson A, Hernell O. Breast-feeding protects against celiac disease in childhood—epidemiological evidence. Integrating Population Outcomes, Biological Mechanisms and Research Methods in the Study of Human Milk and Lactation: Springer; 2002:115-123.
  • Ag ostoni C, Shamir R. Can a change in policy of complementary infant feeding reduce the risk for Type 1 Diabetes and celiac disease? Pediatric endocrinology reviews: PER. 2008;6(1):2.
  • Sz ajewska H, Chmielewska A, Piescik-Lech M, et al. Systematic review: early infant feeding and the prevention of coeliac disease. Aliment Pharmacol Ther 2012;36(7):607-618.
  • St robel S. Immunity induced after a feed of antigen during early life: oral tolerance v. sensitisation. Proceedings of the Nutrition Society 2001;60(04):437-442.
  • Cu mmins AG, Thompson FM. Effect of breast milk and weaning on epithelial growth of the small intestine in humans. Gut 2002;51(5):748-754.
  • Iv arsson A, Persson L, Nyström L, et al. Epidemic of coeliac disease in Swedish children. Acta Paediatrica 2000;89(2):165-171.
  • Jil l M. Norris, Katherine Barriga, Edward J. Hoffenberg, et al. Risk of Celiac Disease Autoimmunity and Timing of Gluten Introduction in the Diet of Infants at Increased Risk of Disease. JAMA 2005 293:2343-2351.
  • Hop man EG, Kiefte-de Jong JC, le Cessie S, Moll HA, Witteman JC, Bleeker SE, Mearin ML, et al. Food questionnaire for assessment of infant gluten consumption. Clinical Nutrition 2007;26(2):264-271.
  • Mic haelsen K, Weile B, Larsen P, Samuelson G, Krasilnikoff P. Does the low intake of wheat in Danish infants cause the low incidence rate of coeliac disease? Acta Paediatrica 1993;82(6‐7):605-606.
  • Weil e B, Cavell B, Nivenius K, Krasilnikoff PA. Striking differences in the incidence of childhood celiac disease between Denmark and Sweden: a plausible explanation. Journal of Pediatric Gastroenterology and Nutrition 1995;21(1):64-68.
  • Gupt a R, Reddy DN, Makharia GK, Sood A, Ramakrishna BS, Yachha SK, et al. Indian task force for celiac disease: current status. World journal of gastroenterology: WJG 2009;15(48):6028.
  • Cata ssi C, Rossini M, Rätsch I, Bearzi I, Santinelli A, Castagnani R, et al. Dose dependent effects of protracted ingestion of small amounts of gliadin in coeliac disease children: a clinical and jejunal morphometric study. Gut 1993;34(11):1515-1519.
  • Doher ty M, Barry R. Gluten-induced mucosal changes in subjects without overt small-bowel disease. The Lancet 1981;317(8219):517-520.
  • Agost oni C, Decsi T, Fewtrell M, Goulet O, Kolacek S, Koletzko B, et al. Complementary Feeding A Commentary by the ESPGHAN. Journal of Pediatric Gastroenterology and Nutrition 2008;46:99–110.
  • Johnst on M, Landers S, Noble L, Szucs K, Viehmann L. Breastfeeding and the use of human milk. Pediatrics 2012;129(3):e827-841.
  • Deveci oğlu E, Gökçay G. Tamamlayıcı Beslenme. Çocuk Dergisi 2012;12(4):159-163.

Çölyak Hastalığının Önlenmesinde Bebek Beslenmesinin Önemi

Year 2014, Issue: 1, 15 - 19, 01.03.2014

Nevin Şanlıer Sabriye Bolluk

Abstract

Çölyak hastalığı ÇH genetik olarak duyarlı kişilerde gluten ve prolaminlerin neden olduğu genetik ve çevresel faktörlerin rol oynadığı multifaktöriyel bir sorundur. Son yıllarda çocuklarda özellikle anne sütü verilme süresi, tamamlayıcı beslenmeye erken başlama ve hayatın ilerleyen dönemlerinde ÇH’nın gelişimi üzerine glutenle tanışma zamanı ve miktarının etkileri vb. konular üzerinde durulmaktadır. Anne sütünün ÇH’na karşı koruyucu etkileri olduğunu gösteren çalışmalar olmasına rağmen herhangi bir koruyucu etkisi olmadığını gösteren çalışmalar da mevcut olup uzun dönemde ÇH gelişimine karşı koruyucu olduğunu gösteren herhangi bir çalışma da bulunmamaktadır. Bu nedenle anne sütünün ÇH’nın klinik belirtilerinin görülmesini önleyip önlemediği ya da geciktirip geciktirmediği hala çelişkili bir konudur. Avrupa Pediatrik Gastroenteroloji, Hepatoloji ve Beslenme Birliği ESPGHAN glutenle tanışma zamanının hem erken < 4 ay hem de geç >7 ay olmasından kaçılması gerektiğini ve gluten bebeğin beslenme programına eklenirken anne sütü alımının da devam etmesinin gerekliliğini vurgulamaktadır. Gelecekte devam eden çalışmaların tamamlanmasıyla bu konuda daha detaylı bilgiler elde edilecek ve bebek beslenmesinde glutenle tanışma zamanı ve miktarı ile ilgili öneriler tekrar gözden geçirilecektir. Bu derlemede çölyak hastalığının önlenmesinde bebek beslenmesinde anne sütü alımı ve gluten ile ilgili çalışmalar irdelenmiştir

Keywords

çölyak bebek beslenmesi anne sütü

References

  • Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. Journal of Pediatric Gastroenterology and Nutrition. 2012;54(1):136-160.
  • Jabri B, Kasarda DD, Green PH. Innate and adaptive immunity: the yin and yang of celiac disease. Immunological Reviews 2005;206(1):219-231.
  • Dalgıç B, Sarı S, Özcan B, Baştürk B, Ensari A, Eğritaş Ö, et al. Türk çocuklarında çölyak hastalığı ile ilişkili olası etmen ve belirtilerin değerlendirilmesi. Turk Arch Ped 2011;46:323-330.
  • Göral V, Yıldırım N, Kaplan A, Şit D, Çelik M. The frequency of gluten enteropathy disease. Akademik Gastroenteroloji Dergisi 2007;6(3):144-148.
  • Silano M. Effect of the timing of gluten introduction on the development of celiac disease. World Journal of Gastroenterology 2010;16(16):1939.
  • Doğdu G, Duru NS, Elevli M, Çivilibal M. Tip 1 Diyabetes Mellituslu Çocuklarda Tiroid Otoimmünitesi ve Gluten Duyarlı Enteropati. Haseki Tıp Bülteni 2012;50:39-42.
  • Troncone R, Ivarsson A, Szajewska H, Mearin ML, Members of European Multistakeholder Platform on CD. Review article: future research on coeliac disease - a position report from the European multistakeholder platform on coeliac disease (CDEUSSA). Aliment Pharmacol Ther 2008;27(11):1030-1043.
  • Hogen Esch CE, Rosen A, Auricchio R, Romanos J, Chmielewska A, Putter H, et al. The PreventCD Study design: towards new strategies for the prevention of coeliac disease. European Journal of Gastroenterology & Hepatology 2010;22(12):1424-1430.
  • Samur G. Anne Sütü. TC Sağlık Bakanlığı Temel S ağlık Hizmetleri Genel Müdürlüğü Beslenme ve Fiziksel Aktiviteler Daire Başkanlığı Yay., Klasmat Mat., Ankara. 2008. http://www.seah.gov.tr/pdf/anne_sutu. pdf Erişim tarihi: 15.11.2013
  • Köksal G, Özel HG. Bebek beslenmesi. Sağlık Bakanlığı Yayın. 2008(726). http://www.beslenme.go v.tr/content/files/arastirmalar/ uyelik/beslenme_bilgi_serisi/Kitaplar/a/a_08_bebek_beslenmesi. pdf Erişim tarihi: 15.11.2013
  • Kalkanoğlu HS. Ç ocukluk Çağı Beslenmesinin İleri Yaşama Etkisi. http://www.danoneenstitusu.org.tr/news.php?id=124&cat=9 Erişim tarihi: 15.11.2013
  • Nash S. Does exclusive breast-feeding reduce the risk of coeliac disease in children? British Journal of Community Nursing 2003;8(3):127-132.
  • Peters U, Schneeweiss S, Trautweina EA, Erbersdoblera HF. A Case- Control Study of the Effect o f Infant Feeding on Celiac Disease. Annals of Nutrition & Metabolism 2001;45:135–142.
  • Decker E, Engelmann G, Findeisen A, Gerner P, Laaβ M, Ney D et al. Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. Pediatrics 2010;125(6):e1433-1440.
  • Roberts SE, Williams JG, Meddings D, Davidson R, Goldacre MJ. Perinatal risk factors and coeliac disease in children and young adults: a record linkage study. Aliment Pharmacol Ther 2009;29(2):222-231.
  • Akobeng AK, Ramanan AV, Buchan I, Heller RF. Effect of breast feeding on risk of coeliac disease: a systematic revi ew and meta- analysis of observational studies. Archives of Disease in Childhood 2006;91(1):39-43.
  • Ascher H, Krantz I, Rydberg L, Nordin P, Kristiansson B. Influence of infant feeding and gluten intake on coeliac disease. Archives of Disease i n Childhood 1997;76:113-117.
  • Auricchio S, Follo D, de Ritis G, Giunta A, Marzorati D, Prampolini L, et al. Does breast feeding protect against the development of clinical symptoms of celiac disease in children? Journal of Pediatric Gastroenterology and Nutrition 1983;2(3):428-433.
  • Greco L, Auricchio S, Mayer M, Grimaldi M. Case control study on nutritional risk factors in celiac disease. Journal of Pediatric Gastroenterology and Nutrition 1998;7(3 ):395-399.
  • Ivarsson A, Hernell O, Stenlund H, Persson LÅ. Breast-feeding protects against celiac disease. Am J Clin Nutr 2002;75:914–921.
  • Norris JM, Barriga K, Hoffenberg EJ, et al. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA : the Journal of the American Medical Association. May 18 2005;293(19):2343-2351.
  • Welander A, Tjernberg AR, Montgomery SM, Ludvigsson J, Ludvigsson JF. Infectious disease and risk of later celiac disease in childhood. Pediatrics. Mar 2010;125(3):e530-536.
  • Ziegler AG, Schmid S, Huber D, Hummel M, Bonifacio E. Early Infant Feeding and Risk of Developing Type 1 Diabetes–Associated Autoantibodies. JAMA : the journal of the American Medical Association 2003;290:1721-1728.
  • Fälth‐Magnusson K, Franzen L, Jansson G, Laurin P, Stenhammai L. Infant feeding history shows distinct differences between Swedish celiac and reference children. Pediatric allergy and immunology 1996;7(1):1-5.
  • M itt K, Uibo O. Low cereal intake in Estonian infants: the possible explanation for the low frequency of coeliac disease in Estonia. European journal of clinical nutrition 1998;52(2):85.
  • A kobeng AK, Heller RF. Assessing the population impact of low rates of breast feeding on asthma, coeliac disease and obesity: the use of a new statistical method. Archives of Disease in Childhood 2007;92(6):483-485.
  • P ersson L, Ivarsson A, Hernell O. Breast-feeding protects against celiac disease in childhood—epidemiological evidence. Integrating Population Outcomes, Biological Mechanisms and Research Methods in the Study of Human Milk and Lactation: Springer; 2002:115-123.
  • Ag ostoni C, Shamir R. Can a change in policy of complementary infant feeding reduce the risk for Type 1 Diabetes and celiac disease? Pediatric endocrinology reviews: PER. 2008;6(1):2.
  • Sz ajewska H, Chmielewska A, Piescik-Lech M, et al. Systematic review: early infant feeding and the prevention of coeliac disease. Aliment Pharmacol Ther 2012;36(7):607-618.
  • St robel S. Immunity induced after a feed of antigen during early life: oral tolerance v. sensitisation. Proceedings of the Nutrition Society 2001;60(04):437-442.
  • Cu mmins AG, Thompson FM. Effect of breast milk and weaning on epithelial growth of the small intestine in humans. Gut 2002;51(5):748-754.
  • Iv arsson A, Persson L, Nyström L, et al. Epidemic of coeliac disease in Swedish children. Acta Paediatrica 2000;89(2):165-171.
  • Jil l M. Norris, Katherine Barriga, Edward J. Hoffenberg, et al. Risk of Celiac Disease Autoimmunity and Timing of Gluten Introduction in the Diet of Infants at Increased Risk of Disease. JAMA 2005 293:2343-2351.
  • Hop man EG, Kiefte-de Jong JC, le Cessie S, Moll HA, Witteman JC, Bleeker SE, Mearin ML, et al. Food questionnaire for assessment of infant gluten consumption. Clinical Nutrition 2007;26(2):264-271.
  • Mic haelsen K, Weile B, Larsen P, Samuelson G, Krasilnikoff P. Does the low intake of wheat in Danish infants cause the low incidence rate of coeliac disease? Acta Paediatrica 1993;82(6‐7):605-606.
  • Weil e B, Cavell B, Nivenius K, Krasilnikoff PA. Striking differences in the incidence of childhood celiac disease between Denmark and Sweden: a plausible explanation. Journal of Pediatric Gastroenterology and Nutrition 1995;21(1):64-68.
  • Gupt a R, Reddy DN, Makharia GK, Sood A, Ramakrishna BS, Yachha SK, et al. Indian task force for celiac disease: current status. World journal of gastroenterology: WJG 2009;15(48):6028.
  • Cata ssi C, Rossini M, Rätsch I, Bearzi I, Santinelli A, Castagnani R, et al. Dose dependent effects of protracted ingestion of small amounts of gliadin in coeliac disease children: a clinical and jejunal morphometric study. Gut 1993;34(11):1515-1519.
  • Doher ty M, Barry R. Gluten-induced mucosal changes in subjects without overt small-bowel disease. The Lancet 1981;317(8219):517-520.
  • Agost oni C, Decsi T, Fewtrell M, Goulet O, Kolacek S, Koletzko B, et al. Complementary Feeding A Commentary by the ESPGHAN. Journal of Pediatric Gastroenterology and Nutrition 2008;46:99–110.
  • Johnst on M, Landers S, Noble L, Szucs K, Viehmann L. Breastfeeding and the use of human milk. Pediatrics 2012;129(3):e827-841.
  • Deveci oğlu E, Gökçay G. Tamamlayıcı Beslenme. Çocuk Dergisi 2012;12(4):159-163.
There are 42 citations in total.

Details

Primary Language Turkish
Journal Section Collection
Authors

Nevin Şanlıer

Sabriye Bolluk

Publication Date March 1, 2014
Published in Issue Year 2014Issue: 1

Cite

EndNote Şanlıer N, Bolluk S (March 1, 2014) Çölyak Hastalığının Önlenmesinde Bebek Beslenmesinin Önemi. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 1 15–19.