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Year 2025, Issue: Kabul Edilen Makaleler

Lütfiye Yaprak , Aslı Çetinkaya Yaprak , İbrahim Başol , Mustafa Ünal , Yusuf Ayaz

https://doi.org/10.31067/acusaglik.1336571

Abstract

References

  • 1. Beauchamp GR. Pediatric keratoplasty: problems in management. J Pediatr Ophthalmol Strabismus. 1979;16:388-94. DOI: 10.3928/0191-3913-19791101-13.
  • 2. Vanathi M, Panda A, Vengayil S, et al. Pediatric keratoplasty. Surv Ophthalmol. 2009;54(2):245-71. DOI: 10.1016/j.survophthal.2008.12.011.
  • 3. Gulias-Cañizo R, Gonzalez-Salinas R, Hernandez-Zimbron LF, et al. Indications and outcomes of pediatric keratoplasty in a tertiary eye care center: A retrospective review. Medicine (Baltimore). 2017;96:e8587. DOI: 10.1097/MD.0000000000008587.
  • 4. Stulting RD, Sumers KD, Cavanagh HD, et al. Penetrating keratoplasty in children. Ophthalmology. 1984;91:1222-30. DOI: 10.1016/s0161-6420(84)34171-9.
  • 5. Cowden JW. Penetrating keratoplasty in infants and children. Ophthalmology. 1990;97:324-8. DOI: 10.1016/s0161-6420(90)32586-1.
  • 6. Mun-Wei L, Md Said H, Punitan R, et al. Indications, Clinical Outcomes, and Survival Rate of Pediatric Penetrating Keratoplasty in Suburban Malaysia: A 10-year Experience. Cureus. 2018;10:e3744. DOI: 10.7759/cureus.3744.
  • 7. Dada T, Sharma N, Vajpayee RB. Indications for pediatric keratoplasty in India. Cornea. 1999;18:296-8. DOI: 10.1097/00003226-199905000-00009.
  • 8. Dana MR, Schaumberg DA, Moyes AL, et al. Outcome of penetrating keratoplasty after ocular trauma in children. Arch Ophthalmol. 1995;113:1503-7. DOI: 10.1001/archopht.1995.01100120033003.
  • 9. Dana MR, Moyes AL, Gomes JA, et al. The indications for and outcome in pediatric keratoplasty. A multicenter study. Ophthalmology. 1995;102:1129-38. DOI: 10.1016/s0161-6420(95)30900-1.
  • 10. Patel HY, Ormonde S, Brookes NH, et al. The indications and outcome of paediatric corneal transplantation in New Zealand: 1991-2003. Br J Ophthalmol. 2005;89:404-8. DOI: 10.1136/bjo.2004.053116.
  • 11. Aasuri MK, Garg P, Gokhle N, et al. Penetrating keratoplasty in children. Cornea. 2000;19:140-4. DOI: 10.1097/00003226-200003000-00004.
  • 12. Low JR, Anshu A, Tan AC, et al. The outcomes of primary pediatric keratoplasty in Singapore. Am J Ophthalmol. 2014;158:496-502. DOI: 10.1016/j.ajo.2014.05.020.
  • 13. Trief D, Marquezan MC, Rapuano CJ, et al. Pediatric corneal transplants. Curr Opin Ophthalmol. 2017;28:477-84. DOI: 10.1097/ICU.0000000000000393.
  • 14. Sharma A, Sharma R. Pediatric Corneal Transplant Surgery: Challenges for Successful Outcome. Nepal J Ophthalmol. 2019;11:197-210. DOI: 10.3126/nepjoph.v11i2.27828.
  • 15. Huang C, O'Hara M, Mannis MJ. Primary pediatric keratoplasty: indications and outcomes. Cornea. 2009;28:1003-8. DOI: 10.1097/ICO.0b013e3181a186c0.
  • 16. Shi W, Jin H, Li S, et al. Indications of paediatric keratoplasty in north China. Clin Exp Ophthalmol. 2007;35:724-7. DOI: 10.1111/j.1442-9071.2007.01618.x.
  • 17. Sharma N, Prakash G, Titiyal JS, et al. Pediatric keratoplasty in India: indications and outcomes. Cornea. 2007;26:810-3. DOI: 10.1097/ICO.0b013e318074ce2e.
  • 18. Karadag R, Chan TC, Azari AA, et al. Survival of Primary Penetrating Keratoplasty in Children. Am J Ophthalmol. 2016;171:95-100. DOI: 10.1016/j.ajo.2016.08.031.
  • 19. Al-Ghamdi A, Al-Rajhi A, Wagoner MD. Primary pediatric keratoplasty: indications, graft survival, and visual outcome. J AAPOS. 2007;11:41-7. DOI: 10.1016/j.jaapos.2006.09.012.
  • 20. Gümüş G, Ökmen H, Kepez Yıldız B, et al. Pediyatrik Keratoplastilerin Klinik ve Demografik Özellikleri. MN Oftalmoloji. 2021;28:214-219
  • 21. Lowe MT, Keane MC, Coster DJ, et al. The outcome of corneal transplantation in infants, children, and adolescents. Ophthalmology. 2011;118:492-7. DOI: 10.1016/j.ophtha.2010.07.006.
  • 22. Xavier Dos Santos Araújo ME, Santos NC, Souza LB, et al. Primary Pediatric Keratoplasty: Etiology, Graft Survival, and Visual Outcome. Am J Ophthalmol. 2020;212:162-8. DOI: 10.1016/j.ajo.2019.12.013.
  • 23. Gulias-Cañizo R, Gonzalez-Salinas R, Hernandez-Zimbron LF, et al. Indications and outcomes of pediatric keratoplasty in a tertiary eye care center: A retrospective review. Medicine (Baltimore). 2017;96:e8587. DOI: 10.1097/MD.0000000000008587.
  • 24. Öztaş Z, Palamar M, Eğrilmez S, et al. Pediatrik olgularda penetran keratoplasti sonuçlarımız. T Klin J Ophthalmol 2012;21:152-9.

Indications, Surgical Techniques and Visual Outcomes of Pediatric Keratoplasty

Year 2025, Issue: Kabul Edilen Makaleler

Lütfiye Yaprak , Aslı Çetinkaya Yaprak , İbrahim Başol , Mustafa Ünal , Yusuf Ayaz

https://doi.org/10.31067/acusaglik.1336571

Abstract

Purpose: In our study, we aimed to present our nine-year pediatric keratoplasty (KP) experience in a tertiary hospital with indications, surgical techniques and visual results.
Methods: Pediatric patients who underwent KP surgery between 2012 and 2021 in our department were retrospectively analyzed. Patients' gender, age at transplantation, indications, surgery technique, combined surgeries, best corrected visual acuity (BCVA), intraocular pressure (IOP), spherical equivalent (SE) values, postoperative complications and follow-up times were evaluated. Surgical success was considered as an IOP <22 mmHg with or without additional surgery, improvement or preservation of visual acuity.
Results: 72 eyes of 63 patients were included in the study. Twenty (31.7%) of the patients were female and 43 (68.3%) were male. There were keratoconus in 46 (63.9%) eyes, corneal scarring in 21 (29.2%) eyes, corneal dystrophy in 4 (5.6%) eyes, and corneal abscess in 1 (1.4%) eye. The mean age of transplantation was 14.03(4-17) years, and the follow-up period was 47.8(6-124) months. Recurrent KP surgery was performed in 1 (1.4%) patient due to graft failure. Preoperative BCVA was 1.13±0.64 logMaR, and postoperative BCVA was 0.45±0.63 logMaR (p<0.01). There were 65 (90%) eyes with a final BCVA of 20/200 or better, and 46 (64%) eyes with a final BCVA of 20/40 or better. Postoperative mean SE was 1.87±3.87 diopters. In 10 patients, higher IOP was detected in the postoperative controls, and trabeculectomy was performed in 2 patients.
Conclusion: After long-term follow-up of our patients, we achieved a vision of 20/200 or better in 63%. Although pre- and post-operative management is quite difficult in pediatric KP cases, long-term visual results can be satisfactory in correctly selected cases.

Keywords

Pediatric corneal transplantation Penetrating keratoplasty Deep Anterior Lamellar Keratoplasty

References

  • 1. Beauchamp GR. Pediatric keratoplasty: problems in management. J Pediatr Ophthalmol Strabismus. 1979;16:388-94. DOI: 10.3928/0191-3913-19791101-13.
  • 2. Vanathi M, Panda A, Vengayil S, et al. Pediatric keratoplasty. Surv Ophthalmol. 2009;54(2):245-71. DOI: 10.1016/j.survophthal.2008.12.011.
  • 3. Gulias-Cañizo R, Gonzalez-Salinas R, Hernandez-Zimbron LF, et al. Indications and outcomes of pediatric keratoplasty in a tertiary eye care center: A retrospective review. Medicine (Baltimore). 2017;96:e8587. DOI: 10.1097/MD.0000000000008587.
  • 4. Stulting RD, Sumers KD, Cavanagh HD, et al. Penetrating keratoplasty in children. Ophthalmology. 1984;91:1222-30. DOI: 10.1016/s0161-6420(84)34171-9.
  • 5. Cowden JW. Penetrating keratoplasty in infants and children. Ophthalmology. 1990;97:324-8. DOI: 10.1016/s0161-6420(90)32586-1.
  • 6. Mun-Wei L, Md Said H, Punitan R, et al. Indications, Clinical Outcomes, and Survival Rate of Pediatric Penetrating Keratoplasty in Suburban Malaysia: A 10-year Experience. Cureus. 2018;10:e3744. DOI: 10.7759/cureus.3744.
  • 7. Dada T, Sharma N, Vajpayee RB. Indications for pediatric keratoplasty in India. Cornea. 1999;18:296-8. DOI: 10.1097/00003226-199905000-00009.
  • 8. Dana MR, Schaumberg DA, Moyes AL, et al. Outcome of penetrating keratoplasty after ocular trauma in children. Arch Ophthalmol. 1995;113:1503-7. DOI: 10.1001/archopht.1995.01100120033003.
  • 9. Dana MR, Moyes AL, Gomes JA, et al. The indications for and outcome in pediatric keratoplasty. A multicenter study. Ophthalmology. 1995;102:1129-38. DOI: 10.1016/s0161-6420(95)30900-1.
  • 10. Patel HY, Ormonde S, Brookes NH, et al. The indications and outcome of paediatric corneal transplantation in New Zealand: 1991-2003. Br J Ophthalmol. 2005;89:404-8. DOI: 10.1136/bjo.2004.053116.
  • 11. Aasuri MK, Garg P, Gokhle N, et al. Penetrating keratoplasty in children. Cornea. 2000;19:140-4. DOI: 10.1097/00003226-200003000-00004.
  • 12. Low JR, Anshu A, Tan AC, et al. The outcomes of primary pediatric keratoplasty in Singapore. Am J Ophthalmol. 2014;158:496-502. DOI: 10.1016/j.ajo.2014.05.020.
  • 13. Trief D, Marquezan MC, Rapuano CJ, et al. Pediatric corneal transplants. Curr Opin Ophthalmol. 2017;28:477-84. DOI: 10.1097/ICU.0000000000000393.
  • 14. Sharma A, Sharma R. Pediatric Corneal Transplant Surgery: Challenges for Successful Outcome. Nepal J Ophthalmol. 2019;11:197-210. DOI: 10.3126/nepjoph.v11i2.27828.
  • 15. Huang C, O'Hara M, Mannis MJ. Primary pediatric keratoplasty: indications and outcomes. Cornea. 2009;28:1003-8. DOI: 10.1097/ICO.0b013e3181a186c0.
  • 16. Shi W, Jin H, Li S, et al. Indications of paediatric keratoplasty in north China. Clin Exp Ophthalmol. 2007;35:724-7. DOI: 10.1111/j.1442-9071.2007.01618.x.
  • 17. Sharma N, Prakash G, Titiyal JS, et al. Pediatric keratoplasty in India: indications and outcomes. Cornea. 2007;26:810-3. DOI: 10.1097/ICO.0b013e318074ce2e.
  • 18. Karadag R, Chan TC, Azari AA, et al. Survival of Primary Penetrating Keratoplasty in Children. Am J Ophthalmol. 2016;171:95-100. DOI: 10.1016/j.ajo.2016.08.031.
  • 19. Al-Ghamdi A, Al-Rajhi A, Wagoner MD. Primary pediatric keratoplasty: indications, graft survival, and visual outcome. J AAPOS. 2007;11:41-7. DOI: 10.1016/j.jaapos.2006.09.012.
  • 20. Gümüş G, Ökmen H, Kepez Yıldız B, et al. Pediyatrik Keratoplastilerin Klinik ve Demografik Özellikleri. MN Oftalmoloji. 2021;28:214-219
  • 21. Lowe MT, Keane MC, Coster DJ, et al. The outcome of corneal transplantation in infants, children, and adolescents. Ophthalmology. 2011;118:492-7. DOI: 10.1016/j.ophtha.2010.07.006.
  • 22. Xavier Dos Santos Araújo ME, Santos NC, Souza LB, et al. Primary Pediatric Keratoplasty: Etiology, Graft Survival, and Visual Outcome. Am J Ophthalmol. 2020;212:162-8. DOI: 10.1016/j.ajo.2019.12.013.
  • 23. Gulias-Cañizo R, Gonzalez-Salinas R, Hernandez-Zimbron LF, et al. Indications and outcomes of pediatric keratoplasty in a tertiary eye care center: A retrospective review. Medicine (Baltimore). 2017;96:e8587. DOI: 10.1097/MD.0000000000008587.
  • 24. Öztaş Z, Palamar M, Eğrilmez S, et al. Pediatrik olgularda penetran keratoplasti sonuçlarımız. T Klin J Ophthalmol 2012;21:152-9.
There are 24 citations in total.

Details

Primary Language English
Subjects Ophthalmology
Journal Section Clinical Research
Authors

Lütfiye Yaprak 0000-0002-0545-324X

Aslı Çetinkaya Yaprak 0000-0002-4285-419X

İbrahim Başol 0000-0002-6409-8751

Mustafa Ünal 0000-0001-8358-6390

Yusuf Ayaz 0000-0003-0196-8534

Early Pub Date December 13, 2024
Publication Date
Submission Date August 2, 2023
Published in Issue Year 2025Issue: Kabul Edilen Makaleler

Cite

EndNote Yaprak L, Çetinkaya Yaprak A, Başol İ, Ünal M, Ayaz Y (December 1, 2024) Indications, Surgical Techniques and Visual Outcomes of Pediatric Keratoplasty. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi Kabul Edilen Makaleler