Öz
Ganoderma
lucidum (Lingzhi in Chinese and Reishi in Japanese) is a popular medicinal
mushroom and has been used for about 2.000 years in Chinese medicine. In the
last 30 years, this fungi has been investigated by modern pharmacologists.
Several studies showed that G. lucidum is effective in modulating immune
functions and inhibiting tumor growth. Other than these effects, G. lucidum has
also been demonstrated that it can be used in the treatment of hypertension,
hyperlipidemia, diabetes mellitus, nephritis, asthma, arthritis, inflammatory
bowel diseases and many other diseases. The certain mechanism of these effects
is still unclear. So, G. lucidum is not suggested as a therapeutic agent. It is
utilized mostly as an immune enhancer and a health supplement. In these paper, we report a case with acute pancreatitis
presenting with different clinical findings.
Ganoderma lucidum ( Japoncada'da Reishi, Çince'de Lingzhi) popüler bir
tıbbi mantardır ve Çin tıbbında yaklaşık
2.000 yıldır kullanılmaktadır Son 30
yılda, bu mantarlar, modern farmakologlar tarafından incelenmiştir . Pek çok
çalışma, G. lucidum'un immün fonksiyonları düzenlediği ve tümör büyümesinin engellenmesinde
etkili olduğunu göstermiştir. Bu etkilerin dışında G. lucidum ayrıca
hipertansiyon, hiperlipidemi, diyabet, nefrit, astım, arterit, iltihaplı
bağırsak hastalıkları ve diğer hastalıkların tedavisinde de kullanılabilir
olduğu gösterilmiştir. Bu etkilerin belli mekanizması hala belirsizdir. Bu
nedenle, G. lucidum bir terapötik madde olarak tavsiye edilmez. Çoğunlukla, bir
bağışıklık arttırıcı ve sağlık için ek gıda olarak kullanılır. Bu olgu
sunumunda, farklı klinik bulgularla kliniğimize başvuran akut pankreatitli bir
olgu sunulmuştur.
Anahtar Kelimeler
Kaynakça
- 1. Benzie IFF, Wachtel-Galor S. Herbal Medicine: Biomolecular and Clinical Aspects.2011;9(2):1-111.
- 2. Lin ZB. Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum. J Pharmacol Sci 2005;99: 144 – 153.
- 3. Batra P, Sharma AK, Khajuria R. Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits. Int J Med Mushrooms. 2013;15(2):127-43.
- 4. Sarles H. Revised classification of pancreatitis-Marseille 1984. Dig Dis Sci 1985; 30:573-4.
- 5. Wang F, Zhou Z, Ren X, Wang Y, Yang R, Luo J, Strappe P.Effect of Ganoderma lucidum spores intervention on glucose and lipid metabolism gene expression profiles in type 2 diabetic rats. Lipids Health Dis. 2015; May 22;14(1):49.
- 6. Gill BS, Sharma P, Kumar R, Kumar S. Misconstrued versatility of Ganoderma lucidum: a key player in multi-targeted cellular signaling. Tumour Biol 2016 Mar;37(3):2789-804. 7. Baby S, Johnson AJ, Govindan B. Secondary metabolites from Ganoderma. Phytochemistry. 2015 Jun;114(1):66-101.
- 8. Liu C, Dunkin D, Lai J, Song Y, Ceballos C, Benkov K, Li XM.Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-κB Signaling. Inflamm Bowel Dis. 2015 Aug;21(8):1918-25.
- 9. Loganathan J, Jiang J, Smith A, Jedinak A, Thyagarajan-Sahu A, Sandusky GE, Nakshatri H, Sliva D. The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes .Int j Oncol. 2014 Jun;44(6):2009-15.
- 10. Koukou Lia, Min Yub, Yang Hua, Guangming Rena, Tingting Zanga, Xiuhong Xua, Juanjuan Qua. Three kinds of Ganoderma lucidum polysaccharides attenuate DDC-induced chronic pancreatitis in mice. Chemico-Biological Interactions. 2016 Mar 5;247:30-8.
Öz
Kaynakça
- 1. Benzie IFF, Wachtel-Galor S. Herbal Medicine: Biomolecular and Clinical Aspects.2011;9(2):1-111.
- 2. Lin ZB. Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum. J Pharmacol Sci 2005;99: 144 – 153.
- 3. Batra P, Sharma AK, Khajuria R. Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits. Int J Med Mushrooms. 2013;15(2):127-43.
- 4. Sarles H. Revised classification of pancreatitis-Marseille 1984. Dig Dis Sci 1985; 30:573-4.
- 5. Wang F, Zhou Z, Ren X, Wang Y, Yang R, Luo J, Strappe P.Effect of Ganoderma lucidum spores intervention on glucose and lipid metabolism gene expression profiles in type 2 diabetic rats. Lipids Health Dis. 2015; May 22;14(1):49.
- 6. Gill BS, Sharma P, Kumar R, Kumar S. Misconstrued versatility of Ganoderma lucidum: a key player in multi-targeted cellular signaling. Tumour Biol 2016 Mar;37(3):2789-804. 7. Baby S, Johnson AJ, Govindan B. Secondary metabolites from Ganoderma. Phytochemistry. 2015 Jun;114(1):66-101.
- 8. Liu C, Dunkin D, Lai J, Song Y, Ceballos C, Benkov K, Li XM.Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-κB Signaling. Inflamm Bowel Dis. 2015 Aug;21(8):1918-25.
- 9. Loganathan J, Jiang J, Smith A, Jedinak A, Thyagarajan-Sahu A, Sandusky GE, Nakshatri H, Sliva D. The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes .Int j Oncol. 2014 Jun;44(6):2009-15.
- 10. Koukou Lia, Min Yub, Yang Hua, Guangming Rena, Tingting Zanga, Xiuhong Xua, Juanjuan Qua. Three kinds of Ganoderma lucidum polysaccharides attenuate DDC-induced chronic pancreatitis in mice. Chemico-Biological Interactions. 2016 Mar 5;247:30-8.
Ayrıntılar
| Bölüm | Olgu Sunumu |
|---|---|
| Yazarlar | |
| Yayımlanma Tarihi | 20 Aralık 2017 |
| Gönderilme Tarihi | 27 Ekim 2016 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 11 Sayı: 4 |
Sağlığın ve birinci basamak bakımın anlaşılmasına ve geliştirilmesine katkıda bulunacak yeni bilgilere sahip yazarların İngilizce veya Türkçe makaleleri memnuniyetle karşılanmaktadır.