Alterations of Neuroretinal and Corneal Thickness in Hashimoto’s Thyroiditis

Osman Okan Olcaysü; Buğra Karasu; Elif Olcaysü; Atilla Çayır; Ali Riza Cenk Celebi

doi:10.31067/acusaglik.1014056

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Alterations of Neuroretinal and Corneal Thickness in Hashimoto’s Thyroiditis

Year 2022, , 234 - 240, 15.03.2022

Osman Okan Olcaysü , Buğra Karasu , Elif Olcaysü , Atilla Çayır , Ali Riza Cenk Celebi

https://doi.org/10.31067/acusaglik.1014056

Abstract

Amaç: Hashimoto tiroiditi (HT) olan hastalarda makula, retina sinir lifi tabakası (RSLT) ve santral kornea kalınlığındaki (SKK) değişiklikleri yaşa uygun sağlıklı kontrol grubu ile karşılaştırmak.
Hastalar ve Yöntemler: Çalışmaya katılan bireyler 2 gruba ayrıldı: HT tanısı olan hastalar (grup 1, n: 54 göz) ve yaşları eşleştirilmiş sağlıklı katılımcılar (grup 2, n: 70 göz). Optik koherens tomografi(OKT) ile kornea, retina ve maküler kalınlıklar ölçüldü. Ortalama sonuç ölçümleri SKK, göz içi basıncı (GİB), merkezi 1 mm foveal kalınlık (MFK), subfoveal koroid kalınlığı (SFKK), toplam maküler hacim (TMH), santral 1 mm foveal hacim (SFH) ve üst, nazal, alt ve temporal kadranlardı.
Bulgular: Ortalama GİB grup 1'de 17.07 ± 2.34μm, grup 2'de 14.20 ± 2.76μm idi (p <0.001). Ortalama SKK'lar 539.44 ± 35.27μm ve 555.06 ± 40.53μm (p = 0.001), SFK'lar 227.35 ± 17.52µm ve 230.38 ± 23.52µm (p = 0.57), SFKK 210,79 ± 20,13µm ve 268,47 ± 24,56µm idi Grup 1 ve grup 2'de sırasıyla, (p <0.001), TMH'lar 7.16 ± 0.35mm3 ve 7.02 ± 0.26mm3 (p = 0.07), CFV'ler 0.17 ± 0.01mm3 ve 0.19 ± 0.07mm3 (p = 0.16) idi. Grup 1'de RSLT kalınlık değerleri, nazal kadran hariç tüm kadranlarda anlamlı olarak daha ince bulundu (p <0.05) (p = 0.086).
Sonuç: HT'ye bağlı hipotiroidizm, kornea ve retinanın gelişimini etkileyen belirleyici bir faktör olabilir. HT'li çocuklarda yüksek GİB ve RSLT kalınlığının azalması, glokom gelişme riskini artırdığı gibi, azalmış SFKK de gelecekte korioretinal bozuklukların gelişimine yatkınlık yaratabilir.

Keywords

Corneal thickness, Hashimoto, retinal nerve fiber layer thickness, macula.

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