Research Article
Year 2024,
, 152 - 158, 01.04.2024
Abstract
References
- 1) Caturegli P, De Remigis A, Rose NR. Hashimoto Thyroidits: clinical and diagnostic criteria. Autoimmun Rev. 2014;13(4-5):391-397.
- 2) Dailey ME, Lindsay S, Shaken R. Relation of thyroid neoplasms to Hashimoto disease of the thyroid gland. AMA Arch Surg 1955;70: 291-297.
- 3) Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Dİffetentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016; 26(1):1-133.
- 4) Gul K, Dirikoc A, Kiyak G, et al. The association between thyroid carcinoma and Hashimoto's thyroiditis is the ultrasonographic and histopathologic characteristics of malignant nodules. Thyroid. 2020;20(8):873-878.
- 5) Shih ML, Lee JA, Hsieh CB, et al. Thyroidectomy for hashimoto’s thyroiditis complications and associated cancers. Thyroid. 2008; 18(7):729-734.
- 6) Repplinger D, Bargren A, Zhang YW, et al. Is Hashimoto thyroiditis a risk factor for papillary thyroid cancer? J Surg Res. 2008; 150(1):49-52.
- 7) Mao L, Zheng C, Ou S, et al. Influence of Hashimoto thyroiditis on diagnosis and treatment of thyroid nodules. Front Endocrinol (Lausanne). 2022; 23(12):1067390.
- 8) Anil C, Goksel S, Gursoy A. Hashimoto’s thyroiditis is not associated with increased risk of thyroid cancer in patients with thyroid nodules a single center prospective study. Thyroid. 2020; 20(6):601-606.
- 9) Kim E S, Lim D J, Baek K H, et al. Thyroglobulin antibody is associated with increased cancer risk in thyroid nodules. Thyroid. 2020; 20(8):885-891.
- 10) Erdogan M, Erdem N, Cetinkalp S, et al. Demographic, clinical, laboratory, ultrasonographic, and cytological features of patients with Hashimoto's thyroiditis results of a university hospital of 769 patients in Turkey. Endocrine. 2009; 36(3):486-490.
- 11) Jie Y, Ruan J, Luo M, et al. Ultrasonographic, clinical, and pathological features of papillary thyroid carcinoma in children and adolescents with or without Hashimoto’s thyroiditis. Front Oncol. 2023 Aug 1:13:1198468.
- 12) Anderson L, Middleton WD, Teefey SA, et al. Hashimoto thyroiditis part 2: sonographic analysis of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis. AJR Am J Roentgenol. 2010; 195(1):216-222.
- 13) Anderson L, Middleton WD, Teefey SA, et al. Hashimoto thyroiditis part 1: sonographic analysis of nodular form of Hashimoto thyroiditis. AJR Am J Roentgenol. 2010; 195(1):208-215.
- 14) Ohmori N, Miyakawa M, Ohmori K, et al. Ultrasonographic findings of papillary thyroid carcinoma with Hashimoto’s thyroiditis. Intern Med. 2007; 46(9):547-550.
- 15) Jankovic B, Le KT, Hershman JM. Clinical Review: Hashimoto's thyroiditis and papillary thyroid carcinoma: is there a correlation? J Clin Endocrinol Metab. 2013; 98(2):474-482.
- 16) Sweis NWG, Zayed AA, Jaberi MA, et al. Geographic variation in the association between Hashimotot’s thyroiditis and Papillary thyroid carcinoma, a meta-analysis. Endocrine. 2023; 2.doi:10.1007/s12020-023-03378-8.
- 17) Ahn D, Heo SJ, Park JH, et al. Clinical relationship between Hashimoto’s thyroiditis and papillary thyroid cancer. Acta Oncol. 2011; 50(8):1228-1234.
- 18) Kebebew E, Treseler P A, Ituarte P H G, et al. Coexisting chronic lymphocytic thyroiditis and papillary thyroid cancer revisited. World J Surg. 2001; 25:632-637.
- 19) Crile G Jr. Struma lymphomatosa and carcinoma of the thyroid. Surg Gynecol Obstet. 1978; 147(3):350-352.
- 20) Latrofa F, Ricci D, Grasso L, et al. Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin antibodies. J Clin Endocrinol Metab. 2008; 93(2):591-596.
- 21) Sinclair D. Clinical and laboratory aspects of thyroid autoantibodies. Ann Clin Biochem. 2006; 43(3):173-183.
- 22) Mazakopakis E, Tzortzinis A, Dalieraki-Ott E, et al. Coexistence of Hashimoto’s thyroiditis with papillary thyroid carcinoma. A retrospective study. Hormones (Athens). 2019; 9(4):312-318.
- 23) Castagna MG, Belardini V, Memmo S, et al. Nodules in autoimmune thyroiditis are associated with increased risk of thyroid cancer in surgical series but not in cytological series: Evidence for selection bias. J Clin Endocrinol Metab. 2014; 99(9):3193-3198.
Year 2024,
, 152 - 158, 01.04.2024
Abstract
Background/Purpose: Our aim was to investigate whether Hashimoto’s Thyroiditis (HT) effects the development of thyroid carcinoma or not.
Methods: We examined 772 patients’ file between january 2000 and december 2010 retrospectively at Istanbul University Cerrahpasa Medical School Endocrinology and Metabolism Clinic, whom fine-needle aspiration biopsy (FNAB) were applied. We noted patient’s demographic findings, anti-thyroglobulin antibody (anti-TG) and anti-thyroperoxidase antibody (anti-TPO) levels, ultrasonography (US) and cytology reports. We compared findings of HT patients with nonhashimoto control group.
Results: 393 patients with mean age 46.11 ± 12.53 of whom 39 male and 354 female with HT and thyroid nodules (HT group) were compared with 379 patients with mean age 47.5 ± 12.6 of whom 53 male and 326 female with nonautoimmune thyroid disease and nodules (control group). We found the prevalance of differentiated thyroid carcinoma 6.6% in the HT group and backwards 12.9% in the control group (p=0.03). There were not any distinguishing US findings between groups. Anti-TPO positivity was significantly higher in benign nodules (p=0.008).
Conclusion: Our findings did not point out an increased risk of Hashimoto’s nodules in terms of differentiated thyroid carcinoma development.
References
- 1) Caturegli P, De Remigis A, Rose NR. Hashimoto Thyroidits: clinical and diagnostic criteria. Autoimmun Rev. 2014;13(4-5):391-397.
- 2) Dailey ME, Lindsay S, Shaken R. Relation of thyroid neoplasms to Hashimoto disease of the thyroid gland. AMA Arch Surg 1955;70: 291-297.
- 3) Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Dİffetentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016; 26(1):1-133.
- 4) Gul K, Dirikoc A, Kiyak G, et al. The association between thyroid carcinoma and Hashimoto's thyroiditis is the ultrasonographic and histopathologic characteristics of malignant nodules. Thyroid. 2020;20(8):873-878.
- 5) Shih ML, Lee JA, Hsieh CB, et al. Thyroidectomy for hashimoto’s thyroiditis complications and associated cancers. Thyroid. 2008; 18(7):729-734.
- 6) Repplinger D, Bargren A, Zhang YW, et al. Is Hashimoto thyroiditis a risk factor for papillary thyroid cancer? J Surg Res. 2008; 150(1):49-52.
- 7) Mao L, Zheng C, Ou S, et al. Influence of Hashimoto thyroiditis on diagnosis and treatment of thyroid nodules. Front Endocrinol (Lausanne). 2022; 23(12):1067390.
- 8) Anil C, Goksel S, Gursoy A. Hashimoto’s thyroiditis is not associated with increased risk of thyroid cancer in patients with thyroid nodules a single center prospective study. Thyroid. 2020; 20(6):601-606.
- 9) Kim E S, Lim D J, Baek K H, et al. Thyroglobulin antibody is associated with increased cancer risk in thyroid nodules. Thyroid. 2020; 20(8):885-891.
- 10) Erdogan M, Erdem N, Cetinkalp S, et al. Demographic, clinical, laboratory, ultrasonographic, and cytological features of patients with Hashimoto's thyroiditis results of a university hospital of 769 patients in Turkey. Endocrine. 2009; 36(3):486-490.
- 11) Jie Y, Ruan J, Luo M, et al. Ultrasonographic, clinical, and pathological features of papillary thyroid carcinoma in children and adolescents with or without Hashimoto’s thyroiditis. Front Oncol. 2023 Aug 1:13:1198468.
- 12) Anderson L, Middleton WD, Teefey SA, et al. Hashimoto thyroiditis part 2: sonographic analysis of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis. AJR Am J Roentgenol. 2010; 195(1):216-222.
- 13) Anderson L, Middleton WD, Teefey SA, et al. Hashimoto thyroiditis part 1: sonographic analysis of nodular form of Hashimoto thyroiditis. AJR Am J Roentgenol. 2010; 195(1):208-215.
- 14) Ohmori N, Miyakawa M, Ohmori K, et al. Ultrasonographic findings of papillary thyroid carcinoma with Hashimoto’s thyroiditis. Intern Med. 2007; 46(9):547-550.
- 15) Jankovic B, Le KT, Hershman JM. Clinical Review: Hashimoto's thyroiditis and papillary thyroid carcinoma: is there a correlation? J Clin Endocrinol Metab. 2013; 98(2):474-482.
- 16) Sweis NWG, Zayed AA, Jaberi MA, et al. Geographic variation in the association between Hashimotot’s thyroiditis and Papillary thyroid carcinoma, a meta-analysis. Endocrine. 2023; 2.doi:10.1007/s12020-023-03378-8.
- 17) Ahn D, Heo SJ, Park JH, et al. Clinical relationship between Hashimoto’s thyroiditis and papillary thyroid cancer. Acta Oncol. 2011; 50(8):1228-1234.
- 18) Kebebew E, Treseler P A, Ituarte P H G, et al. Coexisting chronic lymphocytic thyroiditis and papillary thyroid cancer revisited. World J Surg. 2001; 25:632-637.
- 19) Crile G Jr. Struma lymphomatosa and carcinoma of the thyroid. Surg Gynecol Obstet. 1978; 147(3):350-352.
- 20) Latrofa F, Ricci D, Grasso L, et al. Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin antibodies. J Clin Endocrinol Metab. 2008; 93(2):591-596.
- 21) Sinclair D. Clinical and laboratory aspects of thyroid autoantibodies. Ann Clin Biochem. 2006; 43(3):173-183.
- 22) Mazakopakis E, Tzortzinis A, Dalieraki-Ott E, et al. Coexistence of Hashimoto’s thyroiditis with papillary thyroid carcinoma. A retrospective study. Hormones (Athens). 2019; 9(4):312-318.
- 23) Castagna MG, Belardini V, Memmo S, et al. Nodules in autoimmune thyroiditis are associated with increased risk of thyroid cancer in surgical series but not in cytological series: Evidence for selection bias. J Clin Endocrinol Metab. 2014; 99(9):3193-3198.
There are 23 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Endocrinology |
| Journal Section | Research Articles |
| Authors | |
| Early Pub Date | March 27, 2024 |
| Publication Date | April 1, 2024 |
| Submission Date | November 21, 2023 |
| Acceptance Date | January 31, 2024 |
| Published in Issue | Year 2024 |