Use of Tramadol and Meperidine Combination for Postoperative Analgesia in Kidney Transplant Recipients
Abstract
Aim: Postoperative pain is a condition that can develop after all operations and negatively affect the patient's recovery. It is also common in kidney transplant recipients. Especially the choice of analgesics to be used in this patient group is important. The aim of this retrospective study is to evaluate the effectiveness of the combination of tramadol + meperidine used for postoperative analgesia in kidney transplant recipients.
Materials and Methods: Between April 2014 and April 2019, 100 recipient patients who used tramadol + meperidine combination for postoperative analgesia after a kidney transplant at the Istanbul …. University Medical Faculty Organ Transplant Department were retrospectively analyzed. Demographic and clinical features were evaluated.
Results: The mean age of the patients was 47,4 ± 13,1 years. 67 (67%) of the patients were male and 33 (33%) were female. The mean body mass index of the patients was 30.8 ± 4.4 kilograms / square meter (kg / m2). In these patients, 12th hour mean VAS score 2.9 ± 0.8 and 24th hour mean VAS score was 3.1 ± 0.9. No serious side effect was detected associated with the analgesic method in these patients.
Conclusions: The combination of tramadol + meperidine used in kidney transplant recipients appears to be successful for postoperative analgesia.
References
- 1. Arnold RM, Verrico P, Davison SN. Opioid use in renal failure. J Palliat Med 2007; 10: 1403-1404.
- 2. Braden JB, Russo J, Fan MY et al. Emergency department visits among recipients of chronic opioid therapy. Arch Intern Med 2010; 170: 1425-1432.
- 3. Manchikanti KN, Manchikanti L, Damron KS et al. Increasing deaths from opioid analgesics in the United States: an evaluation in an interventional pain management practice. J Opioid Manag 2008; 4: 271-283.
- 4. Williams M, Milner QJ. Postoperative analgesia following renal transplantation current practice in the UK. Anaesthesia 2003; 58: 712 713.
- 5. American Society of Anesthesiologists Task Force on Neuraxial Opioids, Horlocker TT, Burton AW, et al. Practice guidelines for the prevention, detection, and management of respiratory depression associated with neuraxial opioid administration. Anesthesiology 2009; 110: 218 230.
- 6. Carroll IR, Angst MS, Clark JD. Management of perioperative pain in patients chronically consuming opioids. Reg Anesth Pain Med 2004; 29: 576 591.
- 7. Devys JM, Mora A, Plaud B, et al. Intrathecal + PCA morphine improves analgesia during the first 24 hr after major abdominal surgery compared to PCA alone. Can J Anaesth 2003; 50: 355 361.
- 8. Benyamin R, Trescot AM, Datta S et al. Opioid complications and side effects. Pain Physician 2008; 11: 105–120.
- 9. Byas-Smith MG, Chapman SL, Reed B et al. The effect of opioids on driving and psychomotor performance in patients with chronic pain. Clin J Pain 2005; 21: 345-352.
- 10. I. Madeira, R. Frada, J. Marvão, F.et al. Morphine Patient Controlled Analgesia for Postoperative Analgesia in Patients Who Have Transplanted Cadaver Donor KidneysTransplantation Proceedings,2011; 43: 125-130.
- 11.Farag E, Guirguis M.N, Helou M. et al. Continuous transversus abdominis plane block catheter analgesia for postoperative pain control in renal transplant. J Anesth. 2015; 29: 4–8.
Böbrek Nakli Alıcılarında Postoperatif Analjezi İçin Tramadol + Meperidine Kombinasyonunun Kullanımı. Tek Merkez Deneyimi
Abstract
Amaç: Ameliyat sonrası ağrı, tüm ameliyatlardan sonra gelişebilen ve hastanın iyileşmesini olumsuz yönde etkileyen bir durumdur. Böbrek nakli alıcılarında da yaygındır. Özellikle bu hasta grubunda kullanılacak analjeziklerin seçimi önemlidir. Bu retrospektif çalışmanın amacı, böbrek nakli alıcılarında postoperatif analjezi için kullanılan tramadol + meperidine kombinasyonunun etkinliğinin değerlendirilmesidir.
Gereç ve Yöntem: Nisan 2014 - Nisan 2019 tarihleri arasında İstanbul …. Üniversitesi Tıp Fakültesi Hastanesi Organ Nakli Bölümü'nde, böbrek nakli sonrası postoperatif analjezi için tramadol + meperidine kombinasyonu kullanılan 100 alıcı hasta retrospektif olarak incelendi. Bu hastaların demografik ve klinik özellikleri değerlendirildi.
Bulgular: Hastaların yaş ortalaması 47,4 ± 13,1 yıl idi. Hastaların 67’i (% 67) erkek, 33’ü (% 33) kadın idi. Hastaların ortalama vücut kitle indeksi 30.8 ± 4.4 kilogram / metrekare (kg / m2) idi. 12. saat ortalama VAS skoru 2.9 ± 0.8, 24. saat ortalama VAS skoru 3.1 ± 0.9 idi. Bu hastalarda analjezik yöntemle ilişkili ciddi bir yan etki saptanmadı.
Sonuç: Böbrek nakli alıcılarında, postoperatif analjezi için kullanılan tramadol + meperidine kombinasyonu başarılı görülmektedir.
Keywords
References
- 1. Arnold RM, Verrico P, Davison SN. Opioid use in renal failure. J Palliat Med 2007; 10: 1403-1404.
- 2. Braden JB, Russo J, Fan MY et al. Emergency department visits among recipients of chronic opioid therapy. Arch Intern Med 2010; 170: 1425-1432.
- 3. Manchikanti KN, Manchikanti L, Damron KS et al. Increasing deaths from opioid analgesics in the United States: an evaluation in an interventional pain management practice. J Opioid Manag 2008; 4: 271-283.
- 4. Williams M, Milner QJ. Postoperative analgesia following renal transplantation current practice in the UK. Anaesthesia 2003; 58: 712 713.
- 5. American Society of Anesthesiologists Task Force on Neuraxial Opioids, Horlocker TT, Burton AW, et al. Practice guidelines for the prevention, detection, and management of respiratory depression associated with neuraxial opioid administration. Anesthesiology 2009; 110: 218 230.
- 6. Carroll IR, Angst MS, Clark JD. Management of perioperative pain in patients chronically consuming opioids. Reg Anesth Pain Med 2004; 29: 576 591.
- 7. Devys JM, Mora A, Plaud B, et al. Intrathecal + PCA morphine improves analgesia during the first 24 hr after major abdominal surgery compared to PCA alone. Can J Anaesth 2003; 50: 355 361.
- 8. Benyamin R, Trescot AM, Datta S et al. Opioid complications and side effects. Pain Physician 2008; 11: 105–120.
- 9. Byas-Smith MG, Chapman SL, Reed B et al. The effect of opioids on driving and psychomotor performance in patients with chronic pain. Clin J Pain 2005; 21: 345-352.
- 10. I. Madeira, R. Frada, J. Marvão, F.et al. Morphine Patient Controlled Analgesia for Postoperative Analgesia in Patients Who Have Transplanted Cadaver Donor KidneysTransplantation Proceedings,2011; 43: 125-130.
- 11.Farag E, Guirguis M.N, Helou M. et al. Continuous transversus abdominis plane block catheter analgesia for postoperative pain control in renal transplant. J Anesth. 2015; 29: 4–8.
Details
| Primary Language | English |
|---|---|
| Subjects | Anaesthesiology |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | April 1, 2021 |
| Submission Date | February 17, 2020 |
| Published in Issue | Year 2021 |