Abstract
References
- 1.Wright JL, Levy RD and Churg A. Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment. Thorax. 2005;60:605-9. DOI: 10.1136/thx.2005.042994.
- 2. Chen X, Liu K, Wang Z, et al. Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension. Int J Chron Obstruct Pulmon Dis. 2015;10:2525-33. DOI: 10.2147/COPD.S94211.
- 3. Truong QA, Massaro JM, Rogers IS, et al. Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study. Circ Cardiovasc Imaging. 2012;5:147-54. DOI:10.1161/CIRCIMAGING.111.968610
- 4. Barberà JA and Blanco I. Pulmonary hypertension in patients with chronic obstructive pulmonary disease: advances in pathophysiology and management. Drugs. 2009;69(9):1153-71. DOI: 10.2165/00003495-200969090-00002.
- 5. Sakao S, Voelkel NF and Tatsumi K. The vascular bed in COPD: pulmonary hypertension and pulmonary vascular alterations. Eur Respir Rev. 2014;23:350-5. DOI: 10.1183/09059180.00007913.
- 6. Shujaat A, Bajwa AA and Cury JD. Pulmonary Hypertension Secondary to COPD. Pulm Med. 2012;2012:203952. DOI: 10.1155/2012/203952.
- 7. Lynch DA, Austin JH, Hogg JC, et al. CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society. Radiology. 2015;277:192-205. DOI: 10.1148/radiol.2015141579.
- 8. Matsuoka S, Yamashiro T, Washko GR, et al. Quantitative CT assessment of chronic obstructive pulmonary disease. Radiographics. 2010;30:55-66. DOI: 10.1148/rg.301095110.
- 9. Shin S, King CS, Brown AW, et al. Pulmonary artery size as a predictor of pulmonary hypertension and outcomes in patients with chronic obstructive pulmonary disease. Respir Med. 2014;108:1626-32. DOI: 10.1016/j.rmed.2014.08.009.
Evaluation of the Relationship Between Chronic Obstructive Pulmonary Diseases and Pulmonary Artery Diameter on Computed Tomography
Abstract
Purpose: To study that how the non-asthma chronic obstructive pulmonary diseases (non-asthma-COPD) affect pulmonary artery diameters.
Methods: The main pulmonary artery diameter (MPAD), right and left main pulmonary artery diameter (RPAD-LPAD), and the ratio of MPAD to ascending aorta diameter (AAD) (MPAD/AAD) in all subjects of the sample were assessed. Cases with non-asthma-COPD were classified as Group 1; those who were not was categorized into Group 2. The link between non-asthma-COPD and diameters of pulmonary artery and also the ratio of MPAD/AAD was evaluated statistically according to the groups.
Results: In the study in which a total of 905 cases were evaluated, 138 in Group 1; 767 in Group 2. The patients' average age was 44.82 ± 16.53 (18-82). It was discovered that there is a statistically significant relationship between MPAD, RPAD and LPAD values and non-asthma-COPD, and it was higher in Group 1 (p=0.049, p=0.011, p=0.022; p<0,05, respectively). The MPAD/AAD value of the cases in Group 1 was discovered to be slightly higher than Group 2 (p=0.006; p<0,01). While the cut-off value for MPAD is ≥23.5 mm, the odds ratio was 1.573 (95% CI: 1.092-2.267); while the cut-off value for MPAD/AAD was ≥0.88, the odds ratio was 1.918 (95% CI: 1.253-2.938). According to ROC analysis, MPAD values were more specific for non-asthma-COPD than MPAD/AAD ratio, but MPAD/AAD ratio was more sensitive.
Conclusion: Although there is a relationship between non-asthma-COPD and MPAD, RPAD, LPAD; the ratio of MPAD /AAD is more sensitive for the presence of non-asthma-COPD.
Keywords
pulmonary hypertension chronic obstructive pulmonary disease emphysema bronchiectasis main pulmonary artery chest CT
References
- 1.Wright JL, Levy RD and Churg A. Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment. Thorax. 2005;60:605-9. DOI: 10.1136/thx.2005.042994.
- 2. Chen X, Liu K, Wang Z, et al. Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension. Int J Chron Obstruct Pulmon Dis. 2015;10:2525-33. DOI: 10.2147/COPD.S94211.
- 3. Truong QA, Massaro JM, Rogers IS, et al. Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study. Circ Cardiovasc Imaging. 2012;5:147-54. DOI:10.1161/CIRCIMAGING.111.968610
- 4. Barberà JA and Blanco I. Pulmonary hypertension in patients with chronic obstructive pulmonary disease: advances in pathophysiology and management. Drugs. 2009;69(9):1153-71. DOI: 10.2165/00003495-200969090-00002.
- 5. Sakao S, Voelkel NF and Tatsumi K. The vascular bed in COPD: pulmonary hypertension and pulmonary vascular alterations. Eur Respir Rev. 2014;23:350-5. DOI: 10.1183/09059180.00007913.
- 6. Shujaat A, Bajwa AA and Cury JD. Pulmonary Hypertension Secondary to COPD. Pulm Med. 2012;2012:203952. DOI: 10.1155/2012/203952.
- 7. Lynch DA, Austin JH, Hogg JC, et al. CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society. Radiology. 2015;277:192-205. DOI: 10.1148/radiol.2015141579.
- 8. Matsuoka S, Yamashiro T, Washko GR, et al. Quantitative CT assessment of chronic obstructive pulmonary disease. Radiographics. 2010;30:55-66. DOI: 10.1148/rg.301095110.
- 9. Shin S, King CS, Brown AW, et al. Pulmonary artery size as a predictor of pulmonary hypertension and outcomes in patients with chronic obstructive pulmonary disease. Respir Med. 2014;108:1626-32. DOI: 10.1016/j.rmed.2014.08.009.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Research Article |
| Authors | |
| Publication Date | January 1, 2022 |
| Submission Date | May 1, 2021 |
| Published in Issue | Year 2022 |