Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors

Zeynep Turan; Mahir Topaloğlu; Özden Özyemişçi Taşkıran

doi:10.31067/acusaglik.1314895

EN

Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors

Abstract

Background/Purpose:: The aim of this retrospective study is to determine the functional capacity, global muscle weakness and quality of life in COVID-19 survivors. Acute respiratory distress syndrome survivors frequently develop impaired physical function, quality of life, and muscle weakness. Methods: Acute respiratory distress syndrome survivors related to COVID-19 underwent standardized physical clinical evaluation, Medical Research Council-sumscore, hand-grip strength, 6-minute walk test, 5 repetition-chair-stand test, timed up and go test and Short form-36 evaluation following 4-6 weeks after hospital discharge in Physical Medicine and Rehabilitation Outpatient Clinic. Results: Fifteen patients (10 men, 5 women) with median age 69 years and length of intensive care unit stay 10 days were analyzed. There were impairments in 6-minute walk test, 5 repetition-chair-stand test, hand-grip strength and, Role-physical, Role-emotional and Social functioning domains of Short form-36. 6-minute walk distance was negatively correlated with timed up and go. SF-physical functioning was positively correlated with hand-grip strength, Medical Research Council-sumscore and 5 repetition-chair-stand. SF-general health was positively correlated with hand-grip strength. Conclusion: There were varying degrees of functional impairment in survivors. Therefore, it could add advantage to assess these patients after nearly 4-6 weeks following discharge in order to ascertain rehabilitation needs and giving appropriate therapies.

Keywords

References

1 Negrini F, De Sire A, Andrenelli E, et al. Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane Rehabilitation Field as of April 30th, 2021. Eur J Phys Rehabil Med. 2021. DOI:10.23736/S1973-9087.21.07125-2
2 Held N and Moss M. Optimizing Post-Intensive Care Unit Rehabilitation. Turk Thorac J. 2019;20:147-52. DOI:10.5152/TurkThoracJ.2018.18172
3 Ngai JC, Ko FW, Ng SS, et al. The long-term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status. Respirology. 2010;15:543-50. DOI:10.1111/j.1440-1843.2010.01720.x
4 Liu K, Zhang W, Yang Y, et al. Respiratory rehabilitation in elderly patients with COVID-19: A randomized controlled study. Complement Ther Clin Pract. 2020;39:101166. DOI:10.1016/j.ctcp.2020.101166
5 Spielmanns M, Pekacka-Egli AM, Schoendorf S, et al. Effects of a Comprehensive Pulmonary Rehabilitation in Severe Post-COVID-19 Patients. Int J Environ Res Public Health. 2021;18. DOI:10.3390/ijerph18052695
6 Curci C, Pisano F, Bonacci E, et al. Early rehabilitation in post-acute COVID-19 patients: data from an Italian COVID-19 Rehabilitation Unit and proposal of a treatment protocol. Eur J Phys Rehabil Med. 2020;56:633-41. DOI:10.23736/S1973-9087.20.06339-X
7 Spruit MA, Holland AE, Singh SJ, et al. COVID-19: Interim Guidance on Rehabilitation in the Hospital and Post-Hospital Phase from a European Respiratory Society and American Thoracic Society-coordinated International Task Force. Eur Respir J. 2020. DOI:10.1183/13993003.02197-2020
8 Chan KS, Pfoh ER, Denehy L, et al. Construct validity and minimal important difference of 6-minute walk distance in survivors of acute respiratory failure. Chest. 2015;147:1316-26. DOI:10.1378/chest.14-1808

9 Troosters T, Gosselink R and Decramer M. Six minute walking distance in healthy elderly subjects. Eur Respir J. 1999;14:270-4. DOI:10.1034/j.1399-3003.1999.14b06.x
10 Yoo JI, Choi H and Ha YC. Mean Hand Grip Strength and Cut-off Value for Sarcopenia in Korean Adults Using KNHANES VI. J Korean Med Sci. 2017;32:868-72. DOI:10.3346/jkms.2017.32.5.868
11 Turan Z, Ozyemisci Taskiran O, Erden Z, et al. Does hand grip strength decrease in chronic obstructive pulmonary disease exacerbation? A cross-sectional study. Turk J Med Sci. 2019;49:802-8. DOI:10.3906/sag-1811-22
12 Turan Z, Topaloglu M and Ozyemisci Taskiran O. Medical Research Council-sumscore: a tool for evaluating muscle weakness in patients with post-intensive care syndrome. Crit Care. 2020;24:562. DOI:10.1186/s13054-020-03282-x
13 Hermans G, Clerckx B, Vanhullebusch T, et al. Interobserver agreement of Medical Research Council sum-score and handgrip strength in the intensive care unit. Muscle Nerve. 2012;45:18-25. DOI:10.1002/mus.22219
14 Dowdy DW, Eid MP, Dennison CR, et al. Quality of life after acute respiratory distress syndrome: a meta-analysis. Intensive Care Med. 2006;32:1115-24. DOI:10.1007/s00134-006-0217-3
15 Beaudart C, Mccloskey E, Bruyere O, et al. Sarcopenia in daily practice: assessment and management. BMC Geriatr. 2016;16:170. DOI:10.1186/s12877-016-0349-4
16 Jones SE, Kon SS, Canavan JL, et al. The five-repetition sit-to-stand test as a functional outcome measure in COPD. Thorax. 2013;68:1015-20. DOI:10.1136/thoraxjnl-2013-203576
17 Bohannon RW. Reference values for the five-repetition sit-to-stand test: a descriptive meta-analysis of data from elders. Perceptual and motor skills. 2006;103:215–22. DOI:10.2466/pms.103.1.215-222
18 Bernabeu-Mora R, Medina-Mirapeix F, Llamazares-Herran E, et al. The accuracy with which the 5 times sit-to-stand test, versus gait speed, can identify poor exercise tolerance in patients with COPD: A cross-sectional study. Medicine (Baltimore). 2016;95:e4740. DOI:10.1097/MD.0000000000004740
19 Podsiadlo D and Richardson S. The timed "Up & Go": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39:142-8. DOI:10.1111/j.1532-5415.1991.tb01616.x
20 Bohannon RW. Reference values for the timed up and go test: a descriptive meta-analysis. J Geriatr Phys Ther. 2006;29:64-8. DOI:10.1519/00139143-200608000-00004
21 Jenkins S, Cecins N, Camarri B, et al. Regression equations to predict 6-minute walk distance in middle-aged and elderly adults. Physiother Theory Pract. 2009;25:516-22. DOI:10.3109/09593980802664711
22 Cote CG, Casanova C, Marin JM, et al. Validation and comparison of reference equations for the 6-min walk distance test. Eur Respir J. 2008;31:571-8. DOI:10.1183/09031936.00104507
23 Parry SM, Nalamalapu SR, Nunna K, et al. Six-Minute Walk Distance After Critical Illness: A Systematic Review and Meta-Analysis. J Intensive Care Med. 2021;36:343-51. DOI:10.1177/0885066619885838
24 Curci C, Pisano F, Bonacci E, et al. Early rehabilitation in post-acute COVID-19 patients: data from an Italian COVID-19 rehabilitation unit and proposal of a treatment protocol. A cross-sectional study. Eur J Phys Rehabil Med. 2020. DOI:10.23736/S1973-9087.20.06339-X
25 Fuglebjerg NJU, Jensen TO, Hoyer N, et al. Silent hypoxia in patients with SARS CoV-2 infection before hospital discharge. Int J Infect Dis. 2020;99:100-1. DOI:10.1016/j.ijid.2020.07.014
26 Hui DS, Wong KT, Ko FW, et al. The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivors. Chest. 2005;128:2247-61. DOI:10.1378/chest.128.4.2247
27 Bloem AEM, Veltkamp M, Spruit MA, et al. Validation of 4-meter-gait-speed test and 5-repetitions-sit-to-stand test in patients with pulmonary fibrosis: a clinimetric validation study. Sarcoidosis Vasc Diffuse Lung Dis. 2018;35:317-26. DOI:10.36141/svdld.v35i4.7035
28 Bennell K, Dobson F and Hinman R. Measures of physical performance assessments: Self-Paced Walk Test (SPWT), Stair Climb Test (SCT), Six-Minute Walk Test (6MWT), Chair Stand Test (CST), Timed Up & Go (TUG), Sock Test, Lift and Carry Test (LCT), and Car Task. Arthritis Care Res (Hoboken). 2011;63 Suppl 11:S350-70. DOI:10.1002/acr.20538
29 Chan KS, Zheng JP, Mok YW, et al. SARS: prognosis, outcome and sequelae. Respirology. 2003;8 Suppl:S36-40. DOI:10.1046/j.1440-1843.2003.00522.x
30 Carfi A, Bernabei R, Landi F, et al. Persistent Symptoms in Patients After Acute COVID-19. JAMA. 2020;324:603-5. DOI:10.1001/jama.2020.12603

Details

Primary Language

English

Subjects

Rehabilitation

Journal Section

Research Article

Authors

Zeynep Turan
0000-0001-8142-3467
Türkiye

Mahir Topaloğlu ^*
0000-0002-9364-4512
Türkiye

Özden Özyemişçi Taşkıran
0000-0002-2052-6072
Türkiye

Publication Date

January 31, 2024

Submission Date

June 20, 2023

Acceptance Date

August 30, 2023

Published in Issue

Year 2024 Volume: 15 Number: 1

DOI

https://doi.org/10.31067/acusaglik.1314895

IZ

https://izlik.org/JA85SG27SU

Cite

RIS / Bibtex

APA

Turan, Z., Topaloğlu, M., & Özyemişçi Taşkıran, Ö. (2024). Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 15(1), 39-45. https://doi.org/10.31067/acusaglik.1314895

AMA

1.Turan Z, Topaloğlu M, Özyemişçi Taşkıran Ö. Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors. Acibadem Univ Saglik Bilim Derg. 2024;15(1):39-45. doi:10.31067/acusaglik.1314895

Chicago

Turan, Zeynep, Mahir Topaloğlu, and Özden Özyemişçi Taşkıran. 2024. “Functional Capacity in COVID-19 Related Acute Respiratory Distress Syndrome Survivors”. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 15 (1): 39-45. https://doi.org/10.31067/acusaglik.1314895.

EndNote

Turan Z, Topaloğlu M, Özyemişçi Taşkıran Ö (January 1, 2024) Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 15 1 39–45.

IEEE

[1]Z. Turan, M. Topaloğlu, and Ö. Özyemişçi Taşkıran, “Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors”, Acibadem Univ Saglik Bilim Derg, vol. 15, no. 1, pp. 39–45, Jan. 2024, doi: 10.31067/acusaglik.1314895.

ISNAD

Turan, Zeynep - Topaloğlu, Mahir - Özyemişçi Taşkıran, Özden. “Functional Capacity in COVID-19 Related Acute Respiratory Distress Syndrome Survivors”. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 15/1 (January 1, 2024): 39-45. https://doi.org/10.31067/acusaglik.1314895.

JAMA

1.Turan Z, Topaloğlu M, Özyemişçi Taşkıran Ö. Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors. Acibadem Univ Saglik Bilim Derg. 2024;15:39–45.

MLA

Turan, Zeynep, et al. “Functional Capacity in COVID-19 Related Acute Respiratory Distress Syndrome Survivors”. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, vol. 15, no. 1, Jan. 2024, pp. 39-45, doi:10.31067/acusaglik.1314895.

Vancouver

1.Zeynep Turan, Mahir Topaloğlu, Özden Özyemişçi Taşkıran. Functional Capacity in COVID-19 related Acute Respiratory Distress Syndrome Survivors. Acibadem Univ Saglik Bilim Derg. 2024 Jan. 1;15(1):39-45. doi:10.31067/acusaglik.1314895