Helicobacter Pylori Relationship in Cases of Coexistence of Gastritis and Gallbladder Disease

Ramazan Uçak; Ozlem Ton Eryilmaz; Ömer Faruk Dilbaz; Cemal Kaya; Banu Yılmaz Özgüven; Emir Çapkınoğlu; Fevziye Kabukcuoğlu

doi:10.31067/acusaglik.1325344

EN

Helicobacter Pylori Relationship in Cases of Coexistence of Gastritis and Gallbladder Disease

Abstract

Purpose: We aimed to investigate the effect of Helicobacter Pylorii (HP) on the development of gallbladder diseases and cholelithiasis and its relationship with gastritis. Methods: 282 gastritis cases with follow-up and operated gallbladder material were included in the study. All histomorphological findings, presence of HP and other variables were compared. Active inflammation and presence of HP were examined in the gastritis group. The gallbladder (GB) disease group was evaluated in terms of cholelithiasis, inflammation, cholesterolosis, intestinal and pyloric metaplasia, and the presence of HP. Results: Gallbladder HP (+) was higher in female patients than in male patients. The presence of HP in the GB was significantly higher in patients with cholelithiasis than patients without cholelithiasis. The incidence of HP in the GB was higher in patients with active gastritis than in patients with inactive gastritis. The presence of HP in the GB was found to be higher in patients with HP on gastric biopsy. HP was found to be less in cases without cholesterolosis in the GB (p <0.05). Acute inflammation in the gallbladder, pyloric and intestinal metaplasia were not associated with the presence of HP. In HP (+) gastritis cases, the rate of stone and HP association in the GB was higher than the patients with HP (-) gastritis (p <0.05). However, the presence or absence of HP in gastritis cases was not found to affect the rate of cholelithiasis or HP status in the group without cholelithiasis. Conclusion: In our study, correlation with the presence of HP is clearly seen in patients with gastritis and accompanying cholelithiasis. However, there are many parameters affecting the formation of cholelithiasis and other diseases. Therefore, it will be more useful to interpret the effect of HP presence on the GB with prospective studies in series with more cases, using the control group and limiting the number of variables as much as possible.

Keywords

References

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Details

Primary Language

English

Subjects

Surgery (Other) , Pathology

Journal Section

Research Article

Authors

Ramazan Uçak
0000-0002-2999-7495
Türkiye

Ozlem Ton Eryilmaz
0000-0002-6499-7298
Türkiye

Ömer Faruk Dilbaz
0000-0002-5466-1344
Türkiye

Cemal Kaya
0000-0002-6758-9089
Türkiye

Banu Yılmaz Özgüven
0000-0002-3540-4772
Türkiye

Emir Çapkınoğlu ^*
0000-0002-4981-7623
Türkiye

Fevziye Kabukcuoğlu
0000-0002-7705-7510
Türkiye

Early Pub Date

September 23, 2023

Publication Date

October 1, 2023

Submission Date

July 12, 2023

Acceptance Date

August 30, 2023

Published in Issue

Year 1970 Volume: 14 Number: 4

DOI

https://doi.org/10.31067/acusaglik.1325344

IZ

https://izlik.org/JA64UT66LZ

Cite

RIS / Bibtex

EndNote

Uçak R, Ton Eryilmaz O, Dilbaz ÖF, Kaya C, Yılmaz Özgüven B, Çapkınoğlu E, Kabukcuoğlu F (October 1, 2023) Helicobacter Pylori Relationship in Cases of Coexistence of Gastritis and Gallbladder Disease. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 14 4 502–507.