Helicobacter Pylori Might be a Contributing Factor in Gallbladder Polyps or Gallstones: A Single Center Case-Control Matching Study of Turkish İndividuals

Cenk Özkan; Serhan Yılmaz; Emre Bozdağ; Osman Sıbıç; Erkan Somuncu

doi:10.31067/acusaglik.1454441

EN

Helicobacter Pylori Might be a Contributing Factor in Gallbladder Polyps or Gallstones: A Single Center Case-Control Matching Study of Turkish İndividuals

Abstract

Background/Purpose: In recent studies, Helicobacter pylori (Hp) infection; It was stated that it may be associated with diseases such as obesity, diabetes, chronic obstructive pulmonary disease and kidney failure. In our study, we aimed to examine the relationship between Hp infection and gallstones and gallbladder polyps. Methods: Patients who underwent elective cholecystectomy between January 2017 and December 2021 were retrospectively examined. Patients were divided into those with only polyps in the gallbladder (Group P), those with polyps and stones together (Group SP), and those with only stones (Group S). The control group consisted of patients who underwent gastroscopy due to dyspeptic complaints (Group No). The groups were screened for the presence of Helicobacter pylori. Demographic data, comorbidities, presence of hepatosteatosis and laboratory values were recorded and compared. Results: 244 patients were included in the study. HP was positive in 141 (57.8%) of the patients and negative in 103 (42.2%). There were 58 (23.8%) patients in Group P, 22 (9%) in Group SP, 90 (36.9%) in Group S, and 74 (30.3%) in Group No. There was a significant difference in age between Group P and Group No (P = 0.012). Female gender was significantly higher in Group S (P=0.009). Helicobacter pylori positivity rate was significantly higher in Group P and Group SP (P = 0.012). Conclusion: HP infection may be associated with gallbladder polyps. We recommend that prospective randomized controlled studies be supported by large sample data.

Keywords

Ethical Statement

Ethical approval for the study was granted by the hospital in which the procedures were performed (IRB No: KAEK/2024.04.73).

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Details

Primary Language

English

Subjects

Surgery (Other) , Gastroenterology and Hepatology

Journal Section

Research Article

Authors

Cenk Özkan ^*
0000-0001-6801-7704
Türkiye

Serhan Yılmaz
0000-0002-5612-5932
Türkiye

Emre Bozdağ
0000-0002-2729-1667
Türkiye

Osman Sıbıç
0000-0002-7600-9154
Türkiye

Erkan Somuncu
0000-0002-5622-1983
Türkiye

Early Pub Date

September 17, 2024

Publication Date

October 1, 2024

Submission Date

June 5, 2024

Acceptance Date

August 26, 2024

Published in Issue

Year 2024 Volume: 15 Number: 4

DOI

https://doi.org/10.31067/acusaglik.1454441

IZ

https://izlik.org/JA35KU87RD

Cite

RIS / Bibtex

EndNote

Özkan C, Yılmaz S, Bozdağ E, Sıbıç O, Somuncu E (October 1, 2024) Helicobacter Pylori Might be a Contributing Factor in Gallbladder Polyps or Gallstones: A Single Center Case-Control Matching Study of Turkish İndividuals. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 15 4 374–379.

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