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The Effect of Additives in Urine Tubes on Biochemical Analytes
Abstract
Purpose:Using preservative urine tubes for urine analysis has been made a new era. A proportion of compounds in a preservative tube can be listed as follows: Sodium Propionate (94%), ethylparaben (5.6%) and chlorhexidine (0.4%).
Patients and Methods:We study the urinary tube containing preservative (Becton-Dickinson, Franklin Lakes, USA) additives aimed to study whether the effect on some biochemical tests. 24-h urine samples (n=118) were obtained from outpatients for routine urine analysis. They were divided in to the two tubes: containing preservatives tubes and additive free tubes. Six biochemistry parameters (protein, calcium, urea, phosphorus, creatinine, microalbumin) were tested on Beckman Coulter AU680 analyzer.
Results:Results: The results of phosphor in two urine samples were decreased significantly in all of the time points in stability studies(p= 0.02, p < 0.01).
Conclusion:Conclusion: We can conclude that tubes containing preservatives could be used to analyze biochemical parameters which were analyzed. But urine phosphor measurement with the additive tubes should be done promptly after delivery to the laboratory.
Keywords
References
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Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Research Article
Publication Date
December 16, 2020
Submission Date
May 10, 2019
Acceptance Date
September 12, 2019
Published in Issue
Year 2021 Volume: 12 Number: 1