An Overview To Cytokeratin Pattern of Cholesteatoma

Number: 1 March 1, 2015
  • Ahmet Koç
  • Emrah Emre
EN TR

An Overview To Cytokeratin Pattern of Cholesteatoma

Abstract

Cholesteatoma is a destructive pathology characterized with progressive and chronic infiltration of keratinized squamous epithelium that can be seen the middle ear and mastoid regions of temporal bone. It has serious intra and extracranial complications which can be difficult to manage. Embryologic remnants of squamous epithelium, squamous metaplasia of middle ear epithelium, migration of epidermal cells from external ear canal and tympanic membrane and cell seeding because of middle ear surgery or trauma were all stated as causes of cholesteatoma. Cytokeratins are important markers of cell differentiation. The patterns of cytokeratin expression correlate well with the state of keratinocyte proliferation, migration and differentiation. These patterns are known to be affected during the formation of cholesteatoma. Increasing our knowledge about cytokeratin patterns may help us understand the unknown formation of cholesteatoma. In this review article, a literature survey was done about cytokeratin patterns of cholesteatoma

Keywords

References

  1. Gray D. The treatment of cholesteatoma in children. Proceedings of the Royal Society of Medicine, London, 1964;57: 769-771
  2. Osma C, Cureoglu S, Hosoglu S. The complications of chronic otitis media: report of 93 cases. J Laryngol Otol 2000;114:97-100
  3. Sennaroglu L, Sozeri B. Otogenic brain abscess: review of 41 cases. Otolarygol Head Neck Surg 2000;123:751-755
  4. Yetiser S, Tosun F, Kazkayasi M. Facial nevre paralysis due to chronic otitis media. Otol Neurotol 2002;23:580-588
  5. Sade J. Middle ear mucosa. Arch Otolaryngol 1966;84:137
  6. Jansen C. Posterior tympanotomy: access to the middle ear with preservation of the external ear canal. Arch Klin Exp Ohren Kehlkopfheilkd 1967;188:558-9
  7. Sheehy JL, Patterson MR. Intact canal wall tympanoplasty with mastoidectomy. A review of eight years’ experience. Laryngoscope 1967;77:1502-1542
  8. Portmann M. Open or closed technique in surgery of the middle ear. Ann Otol Rhinol Laryngol 1968;77:927-937

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Ahmet Koç

Emrah Emre

Publication Date

March 1, 2015

Submission Date

-

Acceptance Date

-

Published in Issue

Year 2015 Number: 1

EndNote
Koç A, Emre E (March 1, 2015) An Overview To Cytokeratin Pattern of Cholesteatoma. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 1 1–6.