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Answer To “what Is Your Diagnosis?” On P.198
Abstract
seen on the pretibial surfaces, a clinical picture highly different from ACM 4 . The clinical features of nodu- lar amyloidosis with waxy, smooth papules, nodules or plaques on the face, trunk, or genitalia are also characteristic enough to distinguish it from ACM 2 . Acral persistent papular mucinosis may be confused with ACM, because of the presence of multiple, skin coloured papules localized to the hands and wrists. Alcian blue staining is a definite marker for its diag- nosis 5 . Disorders of porphyrin metabolism may be considered in the differential diagnosis of ACM, due to the involvement of sun-exposed areas 1 . However, in our patient lack of true blisters, milia, scarring, and the negative urine test in addition to positive staining with Congo red and amyloid P eliminated porphyria
References
- Pourrabbani S, Marra DE, Iwasaki J, Fincher EF, Ronald LM. Colloid milium: a review and update. J Drugs Dermatol 2007; 6: 293-6.
- Desai AM, Pielop JA, Smith-Zagone MJ, Hsu S. Colloid milium: A histopathologic mimicker of nodular amyloidosis. Arch Dermatol 2006; 142: 784-5.
- Rangioletti F, Barnhill RL. Deposition disorders in
- Dermatopathology. Eds. Barnhill RL, Crowson AN, Magro CM, Piepkorn MW. 3rd ed, 2010, Mc Graw Hill Medical, New York, pp.378-9.
- al-Ratrout JT, Satti MB. Primary localized cutaneous amyloidosis: a clinicopathologic study from Saudi Arabia. Int J Dermatol 1997; 36: 428-34.
- Harris JE, Purcell SM, Griffin TD. Acral persistent papular mucinosis. J Am Acad Dermatol 2004; 51: 982-8.
Details
Primary Language
English
Subjects
-
Journal Section
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Authors
Ayşe Tülin Mansur
Publication Date
September 1, 2014
Submission Date
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Acceptance Date
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Published in Issue
Year 1970 Number: 3