DNA Metilasyonu ve Hastalıklarla İlişkisi

Cansın Güler; Banu Balcı Peynircioğlu

EN TR

DNA Metilasyonu ve Hastalıklarla İlişkisi

Öz

DNA metilasyonu, yeni gelişmelerle birlikte araştırmacılara merak uyandıran en temel epigenetik mekanizmalardan biridir. Teknolojinin gelişmesiyle hızlı ilerlemeler kaydeden analiz yöntemleri sayesinde metilasyonun farklı rollerinin ortaya çıkması, özellikle hastalıklar üzerindeki etkilerinin keşfedilmesini kolaylaştırmıştır. DNA’nın kimyasal değişimiyle genlerde ifadesel farklılıklar sağlayan bu mekanizmada meydana gelebilecek bir hata ya da düzensizlik, birçok hastalığın temelinde yatan sorunları oluşturabilir. DNA metilasyonunun bilinmeyen yönlerinin ortaya çıkarılması, hastalıkların patogenezinin aydınlatılmasına büyük katkılar sağlayacaktır

Anahtar Kelimeler

DNA metilasyonu,epigenetik

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Turkish

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Cansın Güler

Banu Balcı Peynircioğlu

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June 1, 2016

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Year 2016 Number: 2

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https://izlik.org/JA74KB63TE

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Güler C, Peynircioğlu BB (June 1, 2016) DNA Metilasyonu ve Hastalıklarla İlişkisi. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2 61–68.

DNA Metilasyonu ve Hastalıklarla İlişkisi

Dna Methylation and Its Relation With Diseases

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DNA Metilasyonu ve Hastalıklarla İlişkisi

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