KERATOKONUSUN KOLLAJEN ÇAPRAZ BAĞLAMA TEDAVISI SONRASI KORNEA KALINLIĞI VE TOPOGRAFI INDEKSLERI: 18 AYLIK TAKIP VE LITERATÜR ÖZETI

Ayşe Ebru Kılavuzoğlu; Ali Rıza Cenk Çelebi; Cemile Banu Coşar; Asım Bozkurt Şener

EN TR

Corneal Thickness and Topography Indices After Collagen Cross-Linking For Keratoconus: 18 Months Follow-Up and Literature Review

Abstract

Amaç: Keratokonusun çapraz bağlama tedavisi sonrası korneal topografi indekslerinde ve kornea kalınlığında görülen değişikliklerin değerlendirilmesi. Çalışma Planı: Retrospektif Gözlemsel Çalışma Hastalar ve Yöntemler: Keratokonus tedavisi için korneal kollajen çapraz bağlama tedavisi uygulanan hastaların verileri toplandı. Santral kornea kalınlığı SKK , maksimum ve ortalama keratometri Kmax Kort , değerleri ve topografi indeksleri: index of surface variance ISV , index of vertical asymmetry IVA , keratoconus index KI , central keratoconus index CKI , minimum radius of curvature Rmin , index of height asymmetry IHA ve index of height decentration IHD Pentacam ve Wavelight-Allegretto Wave Topolyzer cihazlarının çıktılarından elde edildi. Takip süresi 18 aydı. Bulgular: Çalışmada keratokonus hastalığı olan 10 hastanın 15 gözü değerlendirildi. Santral kornea kalınlığı ameliyattan 1 ay sonra istatistiksel olarak anlamlı şekilde azaldı p=0,003 fakat son takip değerlerinde ameliyat öncesi değerlere göre istatistiksel olarak anlamlı bir fark yoktu p>0,05 . Kmax ve Kort değerleri son kontrollerde ameliyat öncesi değerlere göre istatistiksel olarak farklı değildi p>0,05 . Korneal topografi indekslerinin birçoğu ameliyat sonrası 6. aydan sonra istatistiksel olarak anlamlı şekilde düzeldi p

Keywords

Cornea,corneal topography,keratoconus

References

Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003;135:620–7.
Wollensak G. Crosslinking treatment of progressive keratoconus: new hope. Curr Opin Ophthalmol 2006;17:356–60. https://doi. org/10.1097/01.icu.0000233954.86723.25
Spoerl E, Wollensak G, Seiler T. Increased resistance of crosslinked cornea against enzymatic digestion. Curr Eye Res 2004;29:35–40. https://doi.org/10.1080/02713680490513182
Caporossi A, Baiocchi S, Mazzotta C, Traversi C, Caporossi T. Parasurgical therapy for keratoconus by riboflavin-ultraviolet type A rays induced cross-linking of corneal collagen: preliminary refractive results in an Italian study. J Cataract Refract Surg 2006;32:837–45. https://doi.org/10.1016/j.jcrs.2006.01.091
Raiskup-Wolf F, Hoyer A, Spoerl E, Pillunat LE. Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results. J Cataract Refract Surg 2008;34:795–801. https://doi. org/10.1016/j.jcrs.2007.12.039
Greenstein SA, Fry KL, Hersh PS. Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. J Cataract Refract Surg 2011;37:1282–90. https:// doi.org/10.1016/j.jcrs.2011.01.029
Arbelaez MC, Sekito MB, Vidal C, Choudhury SA. Collagen cross- linking with riboflavin and ultraviolet-A light in keratoconus: one-year results. Oman J Ophthalmol 2009;2:33–8. https://doi. org/10.4103/0974-620X.48420
(TMS-4; Tomey, Erlangen, Germany) 43±0.08 Vinciguerra 2009 02 83 61 23 09 62

Wollensak G, Spoerl E, Seiler T. Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross- linking. J Cataract Refract Surg 2003;29:1780–85.
Toprak I, Yildirim C. Scheimpflug parameters after corneal collagen crosslinking for keratoconus. Eur J Ophthalmol 2013;23:793–8. https://doi.org/10.5301/ejo.5000313
Vinciguerra P, Albe E, Trazza S, Rosetta P, Vinciguerra R, Seiler T, Epstein D. Refractive, topographic, tomographic and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking. Ophthalmology 2009;116:369–78. https://doi.org/10.1016/j. ophtha.2008.09.048
Caporossi A, Mazzotta C, Baiocchi S, Caporossi T. Long- term results of riboflavin ultraviolet A corneal collagen cross- linking for keratoconus in Italy: the Siena eye cross study. Am J Ophthalmol ;149:585–93. https://doi.org/10.1016/j.ajo.2009.10.021
Vinciguerra P, Camesasca FI, Albe E, Trazza S. Corneal collagen cross-linking for ectasia after excimer laser refractive surgery:1-year results. J Refract Surg 2010;26:486–97. https://doi.org/10.3928/1081 X-20090910-02
Richoz O, Mavrakanas N, Pajic B, Hafezi F. Corneal collagen cross- linking for ectasia after LASIK and photorefractive keratectomy. Ophthalmology 2013;120:1354–9. https://doi.org/10.1016/j. ophtha.2012.12.027
Kanellopoulos AJ, Asimellis G. Revisiting keratoconus diagnosis and progression classification based on evaluation of corneal asymmetry indices, derived from Scheimpflug imaging in keratoconic and suspect cases. Clin Ophthalmol 2013;7:1539–48. https://doi. org/10.2147/OPTH.S44741
Wittig-Silva C, Chan E, Islam FM, Wu T, Whiting M, Snibson GR. A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results. Ophthalmology ;121:812–21. https://doi.org/10.1016/j.ophtha.2013.10.028
Ghanem RC, Santhiago MR, Berti T, Netto MV, Ghanem VC. Topographic, corneal wavefront, and refractive outcomes 2 years after collagen crosslinking for progressive keratoconus. Cornea ;33:43–8. https://doi.org/10.1097/ICO.0b013e3182a9fbdf
Toprak I, Yaylalı V, Yildirim C. Factors affecting outcomes of corneal collagen crosslinking treatment. Eye (Lond) 2014;28:41–6. https:// doi.org/10.1038/eye.2013.224
Goldich Y, Barkana Y, Wussuku Lior O, Marcovich AL, Hirsh A, Avni I, Zadok D. Corneal collagen cross-linking for the treatment of progressive keratoconus:3-year prospective outcome. Can J Ophthalmol 2014;49:54–9. https://doi.org/10.1016/j.jcjo.2013.09.002
Sloot F, Soeters N, van der Valk R, Tahzib NG. Effective corneal collagen crosslinking in advanced cases of progressive keratoconus. J Cataract Refract Surg 2013;39:1141–5. https://doi.org/10.1016/j.jcrs.2013.01.045
Toprak I, Yildirim C. Effects of corneal collagen crosslinking on corneal topographic indices in patients with keratoconus. Eye Contact Lens ;39:385–7. https://doi.org/10.1097/ICL.0b013e31829e907f
Poli M, Cornut PL, Balmitgere T, Aptel F, Janin H, Burillon C. Prospective study of corneal collagen cross-linking efficacy and tolerance in the treatment of keratoconus and corneal ectasia: 3-year results. Cornea ;32:583–90. https://doi.org/10.1097/ICO.0b013e31825e8414
Hashemi H, Seyedian MA, Miraftab M, Fotouhi A, Asgari S. Corneal collagen cross-linking with riboflavin and ultraviolet a irradiation for keratoconus: long-term results. Ophthalmology 2013;120:1515–20. https://doi.org/10.1016/j.ophtha.2013.01.012
Viswanathan D, Males J. Prospective longitudinal study of corneal collagen cross-linking in progressive keratoconus. Clin Exp Ophthalmol 2013;41:531–6. https://doi.org/10.1111/ceo.12035
Goldich Y, Marcovich AL, Barkana Y, Mandel Y, Hirsh A, Morad Y, et al. Clinical and corneal biomechanical changes after collagen cross-linking with riboflavin and UV irradiation in patients with progressive keratoconus: results after 2 years of follow-up. Cornea ;31:609–14. https://doi.org/10.1097/ICO.0b013e318226bf4a
Asri D, Touboul D, Fournie P, Malet F, Garra C, Gallois A, et al. Corneal collagen crosslinking in progressive keratoconus: multicenter results from the French National Reference Center for Keratoconus. J Cataract Refract Surg 2011;37):2137–43. https://doi.org/10.1016/j. jcrs.2011.08.026
Koller T, Pajic B, Vinciguerra P, Seiler T. Flattening of the cornea after collagen crosslinking for keratoconus. J Cataract Refract Surg ;37:1488–92. https://doi.org/10.1016/j.jcrs.2011.03.041
Hersh PS, Greenstein SA, Fry KL. Corneal collagen crosslinking for keratoconus and corneal ectasia: One-year results. J Cataract Refract Surg 2011;37:149–60. https://doi.org/10.1016/j.jcrs.2010.07.030
Greenstein SA, Shah VP, Fry KL, Hersh PS. Corneal thickness changes after corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. J Cataract Refract Surg 2011;37:691–700. https://doi.org/10.1016/j.jcrs.2010.10.052
O’Brart DP, Chan E, Samaras K, Patel P, Shah SP. A randomized, prospective study to investigate the efficacy of riboflavin/ultraviolet A (370 nm) corneal collagen cross-linkage to halt the progression of keratoconus. Br J Ophthalmol 2011;95:1519–24. https://doi. org/10.1136/bjo.2010.196493
Henriquez MA, Izquierdo L Jr, Bernilla C, Zakrzewski PA, Mannis M. Riboflavin/Ultraviolet A corneal collagen cross-linking for the treatment of keratoconus: visual outcomes and Scheimpflug analysis. Cornea 2011;30:281–6. https://doi.org/10.1097/ ICO.0b013e3181eeaea1
Coskunseven E, Jankov MR 2nd, Hafezi F. Contralateral eye study of corneal collagen cross-linking with riboflavin and UVA irradiation in patients with keratoconus. J Refract Surg 2009;25:371–6.
Grewal DS, Brar GS, Jain R, Sood V, Singla M, Grewal SP. Corneal collagen crosslinking using riboflavin and ultraviolet-A light for keratoconus: one-year analysis using Scheimpflug imaging. J Cataract Refract Surg 2009;35:425–32. https://doi.org/10.1016/j. jcrs.2008.11.046
Vinciguerra P, Albe E, Trazza S, Seiler T, Epstein D. Intraoperative and postoperative effects of corneal collagen cross-linking on progressive keratoconus. Arch Ophthalmol 2009;127:1258–65. https://doi.org/10.1001/archophthalmol.2009.205
Agrawal VB. Corneal collagen cross-linking with riboflavin and ultraviolet - a light for keratoconus: results in Indian eyes. Indian J Ophtthalmol 2009;57:111–4.
Wittig-Silva C, Whiting M, Lamoureux E, Lindsay RG, Sullivan LJ, Snibson GR. A randomized controlled trial of corneal collagen cross- linking in progressive keratoconus: preliminary results. J Refract Surg 2008;24:S720–5.

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Ayşe Ebru Kılavuzoğlu

Ali Rıza Cenk Çelebi

Cemile Banu Coşar

Asım Bozkurt Şener

Publication Date

March 1, 2018

Submission Date

-

Acceptance Date

-

Published in Issue

Year 1970 Number: 1

IZ

https://izlik.org/JA87NW52LS

Cite

RIS / Bibtex

EndNote

Kılavuzoğlu AE, Çelebi ARC, Coşar CB, Şener AB (March 1, 2018) KERATOKONUSUN KOLLAJEN ÇAPRAZ BAĞLAMA TEDAVISI SONRASI KORNEA KALINLIĞI VE TOPOGRAFI INDEKSLERI: 18 AYLIK TAKIP VE LITERATÜR ÖZETI. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 1 43–51.

Corneal Thickness and Topography Indices After Collagen Cross-Linking For Keratoconus: 18 Months Follow-Up and Literature Review

Corneal Thickness and Topography Indices After Collagen Cross-Linking For Keratoconus: 18 Months Follow-Up and Literature Review

Abstract

Keywords