Tiroid Patolojisinde Proteomik Yaklaşımlar

Yasemin Uçal; Aysel Ozpinar

EN TR

Tiroid Patolojisinde Proteomik Yaklaşımlar

Öz

Tiroid bezinde görülen kanserler en sık görülen endokrin maligniteleri oluşturmaktadır ve bu kanserlerin insidansı son yıllarda önemli ölçüde artmıştır. Günümüzde çok sık rastlanan tiroid nodüllerinin histopatolojik tanısının konulmasını sağlayan en güvenilir ve ucuz yöntem İnce İğne Aspirasyon Biyopsisi’dir İİAB . Ancak, ayırıcı tanıda ayrım kriterlerinin yeterli olmayışı bazı nodüllerin histopatolojik tanılarının başarıyla konulamamasına neden olmaktadır. Bu amaçla son 40 yıldan beri birçok moleküler teknik geliştirilmiş ve farklı moleküler hedeflerin tiroid kanserinin ayırıcı tanısında kullanılması amaçlanmıştır. Ayırıcı tanıya katkısı olabileceği düşünülen genetik mutasyonlar ya da hücre yüzey belirteçleri prevelans farklılıkları nedeniyle klinikte yaygın olarak kullanılmamaktadır

Anahtar Kelimeler

Tiroid Patolojisi,proteomiks,kütle spektrometresi

References

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Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Yasemin Uçal

Aysel Ozpinar

Publication Date

September 1, 2019

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-

Acceptance Date

-

Published in Issue

Year 2019 Number: 3

IZ

https://izlik.org/JA73CP77WH

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RIS / Bibtex

EndNote

Uçal Y, Ozpinar A (September 1, 2019) Tiroid Patolojisinde Proteomik Yaklaşımlar. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 3 357–362.

Tiroid Patolojisinde Proteomik Yaklaşımlar

Proteomics In Thyroid Pathology

Abstract

Keywords

Tiroid Patolojisinde Proteomik Yaklaşımlar

Öz

Anahtar Kelimeler

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

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