The Effect of Neutropenic Diet Adherence On Malnutrition and Duration of Hospital Stay In Children With Acute Lymphoblastic Leukemia

Emine Betül Polat; Binnur Okan Bakır; Ali Ayçiçek

EN TR

The Effect of Neutropenic Diet Adherence On Malnutrition and Duration of Hospital Stay In Children With Acute Lymphoblastic Leukemia

Abstract

Objectives: Neutropenic diet ND was once considered to be important for the protection of patients from neutropenia when chemotherapy continued. The nutritional problems that neutropenic patients are struggling with include decreased quality of life, inadequate nutrition, prolonged hospital stay, gastrointestinal complications, avoidance of food and decrease in cell mediated immunity resulting from vitamin deficiencies. This cross-sectional trial aimed to evaluate the effect of ND adherence on malnutrition and hospital stay.Material and Method: Between 1st July to 1st December 2017, 60 consecutive children with acute lymphoblastic leukemia treated in University of Health Science Kanuni Sultan Süleyman Research and Training Hospital who were between 1 to 18 years of age and of whom 58.3% n=35 were boys and 41.7% n=25 were girls included in the study. Baseline data collection included demographic and anthropometric information body weight, height, mid upper arm circumference, skinfold thickness ; medical history and adherence to ND was evaluated with a dietary survey method with questions asking actual dietary adherence based on the frequency of food consumed within limited food categories.Results: The adherence rate was 61.7% n=37 for ND. The hospital stay was actually significantly lower in the low ND adherence p=0.027 . Patients in the ND adhering group had no statistically significant difference in malnutrition risk compared to ND incompatible patients p=0.524 .Conclusion: ND extends the length of stay in the hospital while it does not affect malnutrition status. Dietary guidelines with fewer limitations for children with cancer would be helpful for improving nutritional status and shortening hospital stays

Keywords

Acute lymphoblastic leukemia,malnutrition,diet

ÇOCUKLUK ÇAĞI AKUT LENFOBLASTIK LÖSEMI TEDAVISI ALAN HASTALARIN NÖTROPENIK DIYET UYUMUNUN MALNUTRISYONA VE HASTANEDE YATIŞ SÜRESINE ETKISI

Öz

Amaç: Nötropenik diyetlerin ND , kemoterapi tedavisi alan hastalarda sık görülen nötropeni nedeniyle enfekte olma durumuna karşı korunmalarında önemli olduğu düşünülmektedir. Nötropeniyle mücadele eden hastalarda görülen diyete ait zorluklar arasında; yaşam kalitesinin azalması, yetersiz beslenme, hastanede kalış süresinin uzaması, gastrointestinal yan etkiler, yemekten kaçınma ve vitamin eksikliğinden kaynaklanan bağışıklığın zayıflaması sayılabilmektedir. Bu kesitsel çalışmada, nötropenik diyete uyumun malnutrisyona ve hastanede yatış süresine etkisini değerlendirmek amaçlanmıştır.Gereç ve Yöntem: 1 Temmuz– 1 Kasım 2017 tarihleri arasında Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi’nde tedavi alan Akut Lenfoblastik Lösemi’li %58,3’i n=35 erkek ve %41,7’si n=25 kızlardan oluşan 60 çocuk hasta çalışmaya dahil edilmiştir. Demografik bilgi toplanmış ve antropometrik ölçümler vücut ağırlığı, boy uzunluğu, üst orta kol çevresi, deri kıvrım kalınlığı , tıbbi öykü alınmış ve ND uyumu kısıtlanmış besin katogorileri içinde bulunan besinlerin tüketim sıklığına yönelik bir anket ile sorgulanmıştır.Bulgular: Nötropenik diyete uyum oranı %61,7 n=37 olarak saptanmış, hastanede yatış süresi nötropenik diyet uyumu daha az olan hastalarda anlamlı olarak daha düşük bulunmuştur p=0,027 . Nötropenik diyet uyumu ile malnütrisyon riski arasında istatistiksel olarak anlamlı bir sonuç bulunanamıştır p=0,524 .Sonuç: Nötropenik diyetin hastanede kalış süresini uzattığı ancak malnutrisyona etkisi olmadığı bulunmuştur. Çocukluk çağı kanserleri için kısıtlaması daha az olan diyet önerileri, beslenme durumunun iyileşmesine ve hastanede kalış süresine olumlu katkıda bulunacaktır

Anahtar Kelimeler

Akut lenfoblastik lösemi,malnutrisyon,diyet

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Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Emine Betül Polat

Binnur Okan Bakır

Ali Ayçiçek

Publication Date

December 1, 2020

Submission Date

-

Acceptance Date

-

Published in Issue

Year 2020 Number: 4

IZ

https://izlik.org/JA55ZG77PX

Cite

RIS / Bibtex

EndNote

Polat EB, Bakır BO, Ayçiçek A (December 1, 2020) The Effect of Neutropenic Diet Adherence On Malnutrition and Duration of Hospital Stay In Children With Acute Lymphoblastic Leukemia. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 4 631–640.