Research Article

Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Volume: 13 Number: 1 January 1, 2022
EN

Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Abstract

Objective: Given that there is limited number of studies investigated joint effect of vitamin D and parathyroid hormone (PTH) in frailty syndrome, we aimed to evaluate association of frailty with serum vitamin D and PTH levels. Materials and Methods: This is a cross-sectional study conducted on individuals aged >65 years. In this cross-sectional study, data were collected using sociodemographic data sheet, Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight (FRAIL) scale and Study of Osteoporotic Fracture (SOF) index via face-to-face interview. The study included data from 513 subjects. Chi-square test was used in analyses. A p value<0.05 was considered as statistically significant. Results: The mean age was 71.9±6.4 years in the study population. Of the subjects, 75.2% were women and 77.2% were married while 61.8% were illiterate and 99.2% had own income. The prevalence of frailty elder was found as 46.8% by FRAIL scale and 51.3% by SOF index while pre-fail elder prevalence was found as 45.2% by FRAIL scale and 33.3% by SOF index. Conclusion: It was found that frail elder prevalence was increased by advancing age, female gender and presence of comorbidity and that low serum vitamin D and elevated PTH levels were closely associated with prevalence of frail elder.

Keywords

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References

  1. 1. Rockwood K, Song X, MacKnight C et al. A global clinical measure of fitness and frailty in elderly people. CMAJ 2005; 173: 489–95. doi: 10.1503/cmaj.050051.
  2. 2. Topinkova E. Aging, disability and frailty. Ann Nutr Metab 2008; 52(Suppl 1): 6–11. https://doi.org/10.1159/000115340
  3. 3. Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults. toward a better understanding of physiology and etiology: Summary from the American Geriatrics Society/ National Institute on Ageing Research Conference on Frailty in Older Adults. J Am Geriat Soc 2006; 54(6):991-1001. doi: 10.1111/j.1532-5415.2006.00745.x.
  4. 4. Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004;59(3):255-63. doi: 10.1093/gerona/59.3.m255.
  5. 5. Rose M, Pan H, Levinson MR, Staples M. Can frailty predict complicated care needs and length of stay? Intern Med J 2014; 44(8),800-5. doi: 10.1111/imj.12502.
  6. 6. Byard RW. Frailty syndrome–medicolegal considerations. Journal of forensic and legal medicine. 2015;30:34-8. Doı: 10.1016/j.jflm.2014.12.016
  7. 7. Zaslavsky O, Cochrane BB, Thompson HJ, Woods NF, Herting JR, LaCroix AA. Frailty: A Review Of The First Decade Of Research. Biological Research For Nursing 2012; 15(4):422-432. doi: 10.1177/1099800412462866.
  8. 8. Shardell M, Hicks GE, Miller RR et al. Association of low vitamin D levels with the frailty syndrome in men and women. J Gerontol A Biol Sci Med Sci 2009; 64: 69–75. doi: 10.1093/gerona/gln007.

Details

Primary Language

English

Subjects

Geriatrics and Gerontology, Health Care Administration

Journal Section

Research Article

Publication Date

January 1, 2022

Submission Date

June 6, 2021

Acceptance Date

September 10, 2021

Published in Issue

Year 2022 Volume: 13 Number: 1

APA
Göçer, Ş., & Balbaloğlu, Ö. (2022). Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 13(1), 119-125. https://doi.org/10.31067/acusaglik.948574
AMA
1.Göçer Ş, Balbaloğlu Ö. Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acibadem Univ Saglik Bilim Derg. 2022;13(1):119-125. doi:10.31067/acusaglik.948574
Chicago
Göçer, Şemsinnur, and Özlem Balbaloğlu. 2022. “Association of Frailty With Serum Vitamin D and Parathyroid Hormone Levels”. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 13 (1): 119-25. https://doi.org/10.31067/acusaglik.948574.
EndNote
Göçer Ş, Balbaloğlu Ö (January 1, 2022) Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 13 1 119–125.
IEEE
[1]Ş. Göçer and Ö. Balbaloğlu, “Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels”, Acibadem Univ Saglik Bilim Derg, vol. 13, no. 1, pp. 119–125, Jan. 2022, doi: 10.31067/acusaglik.948574.
ISNAD
Göçer, Şemsinnur - Balbaloğlu, Özlem. “Association of Frailty With Serum Vitamin D and Parathyroid Hormone Levels”. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 13/1 (January 1, 2022): 119-125. https://doi.org/10.31067/acusaglik.948574.
JAMA
1.Göçer Ş, Balbaloğlu Ö. Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acibadem Univ Saglik Bilim Derg. 2022;13:119–125.
MLA
Göçer, Şemsinnur, and Özlem Balbaloğlu. “Association of Frailty With Serum Vitamin D and Parathyroid Hormone Levels”. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, vol. 13, no. 1, Jan. 2022, pp. 119-25, doi:10.31067/acusaglik.948574.
Vancouver
1.Şemsinnur Göçer, Özlem Balbaloğlu. Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acibadem Univ Saglik Bilim Derg. 2022 Jan. 1;13(1):119-25. doi:10.31067/acusaglik.948574