Abstract
Purpose: The present study was performed to assess elasticity changes in the ocular and periocular structures of patients with primary open angle glaucoma POAG via sonoelastography. Patients and Methods: Forty-three patients 19 male, 24 female; ranging from 45 to 80, mean age, 63.20 ± 2.31 years diagnosed with POAG were prospectively analyzed. This patient group was compared with a control group of 28 individuals 17 male, 11 female; ranging from 40 to 85, mean age, 63.50 ± 1.89 years who had no eye diseases apart from refractive errors. Following an ophthalmologic assessment and B-mode sonography, all participants underwent semiquantitative sonoelastographic analysis. The elasticity of the retrobulbar fat tissue, optic nerve, lens, and retina–choroid–sclera complex RCSC was compared between the two groups via sonoelastography. Student’s t test and the Mann–Whitney U test were used for statistical assessment. Results: There was no significant differences in the degree of elasticity of the ocular and periocular structures between patients with and without POAG. Conclusion: No difference was detected between elasticity levels of ocular and periocular structures in between patients with and without POAG.
Keywords
References
- 1. Quigley HA, Addicks EM, Green WR. Optic nerve damage in human glaucoma III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy. Arch Ophthalmol 1982;100:135–46. [CrossRef]
- 2. Quigley HA, Dunkelberger GR, Green WR. Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. Am J Ophthalmol 1989;107:453–64. [CrossRef]
- 3. Sommer A, Katz J, Quigley HA, Miller NR, Robin AL, Richter RC, Witt KA. Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss. Arch Ophthalmol 1991;109:77–83. [CrossRef]
- 4. Kerrigan-Baumrind LA, Quigley HA, Pease ME, Kerrigan DF, Mitchell RS. Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons. Invest Ophthalmol Vis Sci 2000;41:741–8.
- 5. Hoh ST. Evaluating the optic nerve and retinal nerve fibre layer: the roles of Heidelberg retina tomography, scanning laser polarimetry and optical coherence tomography. Ann Acad Med Singapore 2007;36:194–202.
- 6. Mackenzie PJ, Mikelberg FS. Evaluating optic nerve damage: pearls and pitfalls. Open Ophthalmol J 2009;3:54–8. [CrossRef]
- 7. Hawker MJ, Vernon SA, Tattersall CL, Dua HS. Detecting glaucoma with RADAAR. the Bridlington Eye Assessment Project. Br J Ophthalmol 2006;90:744–8. [CrossRef]
- 8. Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T. Breast Disease: Clinical application of US elastography for diagnosis. Radiology 2006;239:341–50. [CrossRef]
- 9. Yerli H, Yilmaz T, Oztop I. Clinical importance of diastolic sonoelastographic scoring in the management of thyroid nodules. AJNR Am J Neuroradiol 2013;34:E27–30. [CrossRef]
- 10. Pekel G, Ağladıoğlu K, Acer S, Yağcı R, Kaşıkçı A. Evaluation of ocular and periocular elasticity after panretinal photocoagulation: An ultrasonic elastography study. Curr Eye Res 2015;40:332–7. [CrossRef]
- 11. Pekel G, Ağladıoğlu K, Acer S, Bozkurt K, Çetin EN, Yağcı R. Evaluation of ocular elasticity in high myopia. Optom Vis Sci 2015;92:573–8. [CrossRef]
- 12. Vural M, Acar D, Toprak U, Alp MN, Köz ÖG, Sayin B, Abat GK. The evaluation of the retrobulbar orbital fat tissue and optic nerve with strain ratio elastography. Med Ultrason 2015;17:45–8. [CrossRef]
- 13. Detorakis ET, Drakonaki EE, Tsilimbaris MK, Pallikaris IG, Giarmenitis S. Real-time ultrasound elastographic imaging of ocular and periocular tissues: A feasibility study. Ophthalmic Surg Lasers Imaging 2010;41:135–41. [CrossRef]
Abstract
Amaç: Bu çalışmada primer açık açılı glokom PAAG hastalarının oküler ve perioküler yapılarının elastisite değişikliklerinin sonoelastografi ile değerlendirilmesi amaçlandı. Hastalar ve Yöntem: PAAG’li 43 hasta 19 erkek, 24 kadın; 45-80 arası, ortalama yaş, 63.20 ± 2.31 yıl prospektif olarak incelendi. Bu hasta grubu refraksiyon kusuru dışında göz hastalığı olmayan 28 birey 17 erkek, 11 kadın, 40-85 yaş arası, ortalama yaş, 63.50 ± 1.89 yıl kontrol grubu ile karşılaştırıldı. Oftalmolojik değerlendirme ve B-mod ultrasonografi sonrasında, tüm katılımcılara semikuantatif sonoelastografik analiz yapıldı. Retrobulber yağ dokusu, optik sinir, lens ve retina-koroid-sklera kompleksinin RKSK elastikliği iki grup arasında sonoelastografi ile karşılaştırıldı. Student t-test ve Mann–Whitney U testi istatistik değerlendirme için kullanıldı. Bulgular: PAAG’li hastalar ve kontrol grubu arasında ölçülen perioküler ve oküler parametrelerde ortalama strain oranı belirgin farklılık göstermemektedir. Sonuç: Elastisite oranları perioküler ve oküler yapılarda PAAG ve PAAG olmayan hastalar arasında farklılık göstermemektedir.
Keywords
References
- 1. Quigley HA, Addicks EM, Green WR. Optic nerve damage in human glaucoma III. Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy. Arch Ophthalmol 1982;100:135–46. [CrossRef]
- 2. Quigley HA, Dunkelberger GR, Green WR. Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. Am J Ophthalmol 1989;107:453–64. [CrossRef]
- 3. Sommer A, Katz J, Quigley HA, Miller NR, Robin AL, Richter RC, Witt KA. Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss. Arch Ophthalmol 1991;109:77–83. [CrossRef]
- 4. Kerrigan-Baumrind LA, Quigley HA, Pease ME, Kerrigan DF, Mitchell RS. Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons. Invest Ophthalmol Vis Sci 2000;41:741–8.
- 5. Hoh ST. Evaluating the optic nerve and retinal nerve fibre layer: the roles of Heidelberg retina tomography, scanning laser polarimetry and optical coherence tomography. Ann Acad Med Singapore 2007;36:194–202.
- 6. Mackenzie PJ, Mikelberg FS. Evaluating optic nerve damage: pearls and pitfalls. Open Ophthalmol J 2009;3:54–8. [CrossRef]
- 7. Hawker MJ, Vernon SA, Tattersall CL, Dua HS. Detecting glaucoma with RADAAR. the Bridlington Eye Assessment Project. Br J Ophthalmol 2006;90:744–8. [CrossRef]
- 8. Itoh A, Ueno E, Tohno E, Kamma H, Takahashi H, Shiina T. Breast Disease: Clinical application of US elastography for diagnosis. Radiology 2006;239:341–50. [CrossRef]
- 9. Yerli H, Yilmaz T, Oztop I. Clinical importance of diastolic sonoelastographic scoring in the management of thyroid nodules. AJNR Am J Neuroradiol 2013;34:E27–30. [CrossRef]
- 10. Pekel G, Ağladıoğlu K, Acer S, Yağcı R, Kaşıkçı A. Evaluation of ocular and periocular elasticity after panretinal photocoagulation: An ultrasonic elastography study. Curr Eye Res 2015;40:332–7. [CrossRef]
- 11. Pekel G, Ağladıoğlu K, Acer S, Bozkurt K, Çetin EN, Yağcı R. Evaluation of ocular elasticity in high myopia. Optom Vis Sci 2015;92:573–8. [CrossRef]
- 12. Vural M, Acar D, Toprak U, Alp MN, Köz ÖG, Sayin B, Abat GK. The evaluation of the retrobulbar orbital fat tissue and optic nerve with strain ratio elastography. Med Ultrason 2015;17:45–8. [CrossRef]
- 13. Detorakis ET, Drakonaki EE, Tsilimbaris MK, Pallikaris IG, Giarmenitis S. Real-time ultrasound elastographic imaging of ocular and periocular tissues: A feasibility study. Ophthalmic Surg Lasers Imaging 2010;41:135–41. [CrossRef]
Details
| Primary Language | English |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | September 1, 2019 |
| Published in Issue | Year 2019Issue: 3 |