Radiotherapy Induced Changes of Masticatory Muscles and Parotid Glands On Mri In Patients With Nasopharyngeal Carcinoma

Taner Arpacı; Gamze Uğurluer; Gülhan Örekici; Tuğana Akbaş; Meltem Serin

EN TR

Radiotherapy Induced Changes of Masticatory Muscles and Parotid Glands On Mri In Patients With Nasopharyngeal Carcinoma

Abstract

Objective: The aim of this study was to identify radiotherapy RT induced changes of masticatory muscles and parotid glands on magnetic resonance imaging MRI in patients with nasopharyngeal carcinoma NPC .Patients and Methods: Thirty-one patients treated with RT for NPC between 2009-2016 in our instution were included in the study. MRI examinations performed before and after RT were reviewed retrospectively. Transverse diameters and signal intensities of masticatory muscles and parotid glands were evaluated on T2 weighted axial MR images. Normal hypointense signal was scored as 0, mild hyperintensity as 1 and severe hyperintensity as 2. Results:The mean interval between pre-RT MRI and last control MRI was 44 months 12-84 months . Reductions of transverse diameters were; right masseter RM :2.32mm 15% , left masseter LM :2.42mm 15.4% , right medial pterygoid RMP :1.26mm 8.7% , left medial pterygoid LMP :1.71mm 12% , right lateral pterygoid RLP :1.35mm 9.6% , left lateral pterygoid LLP :1.32mm 9.4% , right parotid gland RP :8.22mm 26% , left parotid gland LP :8.87mm 28% . T2 signal changes were; RM: mild 8 cases 26% , LM: mild 5 cases 16% , RMP: mild 5 cases 16% , severe 1 case 3.5% , LMP: mild 4 cases 13% , severe 2 cases 6.5% , RLP and LLP: mild 8 cases 26% , severe 3 cases 9.7% , RP: mild 10 cases 32% , severe 18 cases 58% , LP: mild 10 cases 32% , severe 17 cases 55% . Conclusion: Volume loss and hyperintensity were mostly seen in parotid glands. Masseter was the muscle with highest rate of volume loss and lateral pyterygoid showed the highest rate of hyperintensity in masticatory muscles

Keywords

Magnetic resonance imaging,masticatory muscle,nasopharyngeal carcinoma,parotid gland,radiotherapy

NAZOFARENKS KANSERLİ OLGULARDA RADYOTERAPİ SONRASI MASTİKATÖR KASLARDA VE PAROTİS BEZLERİNDE GELİŞEN DEĞİŞİKLİKLERİN MRG İLE DEĞERLENDİRİLMESİ

Öz

Amaç: Bu çalışmada, nazofarenks kanserli olgularda radyoterapi RT sonrası mastikatör kaslarda ve parotis bezlerinde ortaya çıkan değişikliklerin manyetik rezonans görüntüleme MRG ile değerlendirilmesi amaçlandı. Hastalar ve Yöntem: Kurumumuzda 2009-2016 yılları arasında nazofarenks kanseri tanısıyla RT verilen 31 olgunun RT öncesi ve sonrası çekilen MRG’leri retrospektif olarak değerlendirildi. T2 ağırlıklı aksiyel imajlarda mastikatör kasların ve parotis bezlerinin maksimum transvers çapları ve sinyal özellikleri kaydedildi. Normal hipointens sinyal 0, hafif sinyal artışı 1 ve belirgin sinyal artışı 2 olarak skorlandı. Bulgular: RT öncesi çekilen ve takipte en son çekilen MRG arasındaki ortalama süre 44 aydı 12-84 ay . Sağ masseter kası RM :2.32mm 15% , sol masseter LM :2.42mm 15.4% , sağ medial pterygoid RMP :1.26mm 8.7% , sol medial pterygoid LMP :1.71mm 12% , sağ lateral pterygoid RLP :1.35mm 9.6% , sol lateral pterygoid LLP :1.32mm 9.4% , sağ parotis bezi RP :8.22mm 26% ve sol parotis bezi LP :8.87mm 28% oranında incelme gösterdi. RM 8 olguda 26% hafif, LM 5 olguda 16% hafif, RMP 5 olguda 16% hafif ve 1 olguda 3,5% belirgin, LMP 4 olguda 13% hafif ve 2 olguda 6,5% belirgin, RLP ve LLP 8’er olguda 26% hafif ve 3’er olguda 9,7% belirgin, RP 10 olguda 32% hafif ve 18 olguda 58% belirgin, LP 10 olguda 32% hafif ve 17 olguda 55% belirgin sinyal artışı gösterdi. Sonuç: Hacim kaybı ve sinyal artışı en sık parotis bezlerinde gözlendi. Mastikatör kaslar arasında en sık hacim kaybı masseterde ve en sık sinyal artışı lateral pterygoid kasta saptandı. Radiotherapy induced changes of masticatory muscles and parotid glands on MRI in patients with nasopharyngeal carcinoma

Anahtar Kelimeler

Manyetik rezonans görüntüleme,mastikatör kas,nazofarenks kanseri,parotis bezi,radyoterapi

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Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Taner Arpacı

Gamze Uğurluer

Gülhan Örekici

Tuğana Akbaş

Meltem Serin

Publication Date

December 1, 2019

Submission Date

-

Acceptance Date

-

Published in Issue

Year 1970 Number: 4

IZ

https://izlik.org/JA98KP52BY

Cite

RIS / Bibtex

EndNote

Arpacı T, Uğurluer G, Örekici G, Akbaş T, Serin M (December 1, 2019) Radiotherapy Induced Changes of Masticatory Muscles and Parotid Glands On Mri In Patients With Nasopharyngeal Carcinoma. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 4 621–626.