Research Article
Year 2022,
Volume: 13 Issue: 1, 44 - 50, 01.01.2022
Abstract
References
- 1. De Onis M, Blössner M, Borghi E. Global prevalence and trends of overweight and obesity among preschool children. Am J Clin Nutr. 2010;92:1257–64.
- 2. Withrow D, Alter DA. The economic burden of obesity worldwide: A systematic review of the direct costs of obesity. Obes Rev. 2011;12:131-41.
- 3. Freedman DS, Mei Z, Srinivasan SR, et al. Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa heart study. J Pediatr. 2007;150:12-7.
- 4. Whitlock EP, Williams, SB, Gold R, et al. Screening and interventions for childhood overweight: A summary of evidence for the US Preventive Services Task Force. Pediatrics 2005;116:125–44.
- 5. Ickes MJ, Mullen JM, Manoj TH. Sharma Global School-Based Childhood Obesity Interventions: A Review Int. J. Environ. Res. Public Health 2014;11:8940-61.
- 6. Mumcuoğlu T, Durukan H, Hürmeriç V, et al. Relationship Between Introcular Pressure, Central Corneal Thickness and Visual Field Defects in Glaucoma and Ocular Hypertension. Journal of Glaucoma – Cataract 2006 , Vol 1, Num 2.
- 7. Arıtürk N. Central Corneal Thickness Measurement and its Importance in Glaucoma. Journal of Glaucoma – Cataract 2006 , Vol 1, Num 1.
- 8. Tuncer İ, Karahan E, Zengin MÖ, et al. Comparison of Scheimpflug Imaging and Optical Coherence Tomography in the Measurement of Central Corneal Thickness. Journal of Glaucoma – Cataract 2014 , Vol 9, Num 1.
- 9. Leung CK, Liu S, Weinreb RN, et al. Evaluation of retinal nerve fiber layer progression in glaucoma a prospective analysis with neuroretinal rim and visual field progression. Ophthalmology. 2011;118:1551-57.
- 10. Bardak H, Bardak Y. Comparison of Central Corneal Thickness Measurement By Different Methods in Glaucoma Patients. Journal of Glaucoma – Cataract 2015 , Vol 10, Num 3.
- 11. Farpour-Lambert NJ , Baker JL, Hassapidou M, et al. Childhood Obesity Is a Chronic Disease Demanding Specific Health Care--a Position Statement from the Childhood Obesity Task Force (COTF) of the European Association for the Study of Obesity (EASO). Obes Facts 2015;8(5):342-9.
- 12. Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008 Oct;146(4):496-500.
- 13. Mori K, Ando F, Nomura H, et al. Relationship between intraocular pressure and obesity in Japan. Int J Epidemiol. 2000;29:661-66.
- 14. Cheung N, Wong TY. Obesity and eye diseases. Surv Ophthalmol. 2007;52:180-95.
- 15. Akinci A, Cetinkaya E, Aycan Z, et al. Relationship between intraocular pressure and obesity in children. J Glaucoma. 2007;16:627-30.
- 16. Albuquerque LL, Gaete MI, Figueiroa JN, et al. The correlation between body mass index and intraocular pressure in children. Arq Bras Oftalmol. 2013;76:10-12.
- 17. Gasser P, Stümpfig D, Schötzau A, et al. Body mass index in glaucoma. J Glaucoma. 1999;8:8-11.
- 18. Park SS, Lee EH, Jargal G, et al. The distribution of intraocular pressure and its association with metabolic syndrome in a community. J Prev Med Public Health. 2010;43:125-30.
- 19. Hoffmann EM, Lamparter J, Mirshahi A, et al. Distribution of central corneal thickness and its association with ocular parameters in a large central European cohort: the Gutenberg health study. PLoS One. 2013;8:66158.
- 20. Su DH, Wong TY, Foster PJ, et al. Central corneal thickness and its associations with ocular and systemic factors: the Singapore Malay Eye Study. Am J Ophthalmol. 2009;147:709-16.
- 21. Elflein HM, Pfeiffer N, Hoffmann EM, et al. Correlations between central corneal thickness and general anthropometric characteristics and cardiovascular parameters in a large European cohort from the Gutenberg Health Study.Cornea. 2014;33:359-65.
- 22. Nishitsuka K, Kawasaki R, Kanno M, et al. Determinants and risk factors for central corneal thickness in Japanese persons: the Funagata Study. Ophthalmic Epidemiol. 2011;18:244-49.
- 23. Teberik K, Eski MT, Doğan S, et al.Ocular abnormalities in morbid obesity. Arq Bras Oftalmol. 2019 Jan-Feb;82(1):6-11.
- 24. Badaró E, Novais E, Prodocimo LM, et al. Spectral-domain optical coherence tomography for macular edema. Scientific World Journal. 2014;2014:191847.
- 25. Sakata LM, Deleon-Ortega J, Sakata V, et al. Optical coherence tomography of the retina and optic nerve - a review. Clin Experiment Ophthalmol. 2009;37:90-9.
- 26. Wong AC, Chan CW, Hui SP. Relationship of gender, body mass index, and axial length with central retinal thickness using optical coherence tomography. Eye (Lond). 2005;19:292-97.
- 27. Hirooka K, Manabe S, Tenkumo K, et al. Use of the structure-function relationship in detecting glaucoma progression in early glaucoma. BMC Ophthalmol. 2014;14:118.
- 28. Zheng Y, Cheung CY, Wong TY, et al. Influence of height, weight, and body mass index on optic disc parameters. Invest Ophthalmol Vis Sci. 2010;51:2998-3002.
- 29. Jonas JB, Nangia V, Gupta R, et al. Retinal nerve fibre layer cross-sectional area, neuroretinal rim area and body mass index. Acta Ophthalmol. 2014;92:194-99.
- 30. R T Baran , S O Baran , N F Toraman , et al. Evaluation of intraocular pressure and retinal nerve fiber layer, retinal ganglion cell, central macular thickness, and choroidal thickness using optical coherence tomography in obese children and healthy controls. Niger J Clin Pract. 2019 Apr;22(4):539-545.
- 31. Demir S, Özer S, Alim S, et al. Retinal nerve fiber layer and ganglion-inner plexiform layer thickness in chidren with obesity. Int J Ophthalmol. 2016 Mar 18;9(3):434-8.
- 32. Zhu BD , Li SM, Li H, et al. Retinal nerve fiber layer thickness in a population of 12-year-old children in central China measured by iVue-100 spectral-domain optical coherence tomography: the Anyang Childhood Eye Study. Invest Ophthalmol Vis Sci. 2013;54:8104-11.
Evaluation of the Relationships Between Obesity and Central Retinal Thickness, Retinal Nerve Fiber Layer, Intraocular Pressure, and Central Corneal Thickness in Children
Abstract
Amaç: Bu çalışmanın amacı çocukluk çağı obezitesinin retina sinir lifi tabakası (RSLT), retina kalınlığı, santral kornea kalınlığı ve göz içi basıncı üzerine etkisini araştırmaktır.
Hastalar ve Yöntem: Obeziteli çocuklar (n:24) (Grup 1; n:48 göz) ve sağlıklı çocuklar (n:23) (Grup 2; n:46 göz) çalışmaya dahil edildi. Ortalama RSLT kalınlığı, merkezi 1 mm çapındaki foveal kalınlık (MFK) ve subfoveal koroid kalınlığı (SFKK), fourier domain - optik koherens tomografi (FD-OKT) kullanılarak ölçüldü. Santral kornea kalınlığı (SKK) kontakt ultrasonik pakimetrisi ve göz içi basıncı (GİB) Goldmann aplanasyon tonometrisi kullanılarak ölçüldü.
Bulgular: Ortalama GİB Grup 1'de anlamlı olarak daha yüksek (p=0.002) ve grup 1'de 16.1 ± 3.1 mmHg ve grup 2'de 13.6 ± 3.2 mmHg bulundu. Ortalama RSLT, MFK ve SFKK grup 1'de grup 2'ye göre anlamlı olarak daha düşük bulundu (p < 0.05). Ortalama RSLT grup 1'de 107.9 ± 10.5 µm ve grup 2'de 112.6±11.8 µm olarak saptandı (p=0.001). Ortalama MFK grup 1'de 231.6±14.4 µm ve grup 2'de 245.9±19.98 µm bulundu (p=0.001). Ortalama SFKK sırasıyla grup 1'de 193.3±15.3 µm ve grup 2'de 221 ± 25.1 µm olarak gözlendi (p<0.001). Grup 1'de SKK göreceli olarak daha yüksek olmasına rağmen gruplar arasında istatistiksel olarak anlamlı bir fark gözlenmedi (p=0.08). Obezite varlığı ile ortalama GİB ölçümleri arasında pozitif korelasyon (r = 0.847, p = 0.011) ve ayrıca ortalama RSLT kalınlığı ile hastaların ortalama ağırlığı arasında negative bir korelasyon saptandı (r = - 0.749, p = 0.039).
Sonuç: Bu çalışmada obezitesi olan çocuklarda GİB değerinin yüksekliğinin ve RSLT kalınlığının azalmasının glokom gelişme riskini artırdığı, aynı zamanda azalmış MFK ve SFKK' nın gelecekte makula hastalıklarının gelişimine temel oluşturabileceği göz önünde bulundurulmalıdır.
Keywords
References
- 1. De Onis M, Blössner M, Borghi E. Global prevalence and trends of overweight and obesity among preschool children. Am J Clin Nutr. 2010;92:1257–64.
- 2. Withrow D, Alter DA. The economic burden of obesity worldwide: A systematic review of the direct costs of obesity. Obes Rev. 2011;12:131-41.
- 3. Freedman DS, Mei Z, Srinivasan SR, et al. Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa heart study. J Pediatr. 2007;150:12-7.
- 4. Whitlock EP, Williams, SB, Gold R, et al. Screening and interventions for childhood overweight: A summary of evidence for the US Preventive Services Task Force. Pediatrics 2005;116:125–44.
- 5. Ickes MJ, Mullen JM, Manoj TH. Sharma Global School-Based Childhood Obesity Interventions: A Review Int. J. Environ. Res. Public Health 2014;11:8940-61.
- 6. Mumcuoğlu T, Durukan H, Hürmeriç V, et al. Relationship Between Introcular Pressure, Central Corneal Thickness and Visual Field Defects in Glaucoma and Ocular Hypertension. Journal of Glaucoma – Cataract 2006 , Vol 1, Num 2.
- 7. Arıtürk N. Central Corneal Thickness Measurement and its Importance in Glaucoma. Journal of Glaucoma – Cataract 2006 , Vol 1, Num 1.
- 8. Tuncer İ, Karahan E, Zengin MÖ, et al. Comparison of Scheimpflug Imaging and Optical Coherence Tomography in the Measurement of Central Corneal Thickness. Journal of Glaucoma – Cataract 2014 , Vol 9, Num 1.
- 9. Leung CK, Liu S, Weinreb RN, et al. Evaluation of retinal nerve fiber layer progression in glaucoma a prospective analysis with neuroretinal rim and visual field progression. Ophthalmology. 2011;118:1551-57.
- 10. Bardak H, Bardak Y. Comparison of Central Corneal Thickness Measurement By Different Methods in Glaucoma Patients. Journal of Glaucoma – Cataract 2015 , Vol 10, Num 3.
- 11. Farpour-Lambert NJ , Baker JL, Hassapidou M, et al. Childhood Obesity Is a Chronic Disease Demanding Specific Health Care--a Position Statement from the Childhood Obesity Task Force (COTF) of the European Association for the Study of Obesity (EASO). Obes Facts 2015;8(5):342-9.
- 12. Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008 Oct;146(4):496-500.
- 13. Mori K, Ando F, Nomura H, et al. Relationship between intraocular pressure and obesity in Japan. Int J Epidemiol. 2000;29:661-66.
- 14. Cheung N, Wong TY. Obesity and eye diseases. Surv Ophthalmol. 2007;52:180-95.
- 15. Akinci A, Cetinkaya E, Aycan Z, et al. Relationship between intraocular pressure and obesity in children. J Glaucoma. 2007;16:627-30.
- 16. Albuquerque LL, Gaete MI, Figueiroa JN, et al. The correlation between body mass index and intraocular pressure in children. Arq Bras Oftalmol. 2013;76:10-12.
- 17. Gasser P, Stümpfig D, Schötzau A, et al. Body mass index in glaucoma. J Glaucoma. 1999;8:8-11.
- 18. Park SS, Lee EH, Jargal G, et al. The distribution of intraocular pressure and its association with metabolic syndrome in a community. J Prev Med Public Health. 2010;43:125-30.
- 19. Hoffmann EM, Lamparter J, Mirshahi A, et al. Distribution of central corneal thickness and its association with ocular parameters in a large central European cohort: the Gutenberg health study. PLoS One. 2013;8:66158.
- 20. Su DH, Wong TY, Foster PJ, et al. Central corneal thickness and its associations with ocular and systemic factors: the Singapore Malay Eye Study. Am J Ophthalmol. 2009;147:709-16.
- 21. Elflein HM, Pfeiffer N, Hoffmann EM, et al. Correlations between central corneal thickness and general anthropometric characteristics and cardiovascular parameters in a large European cohort from the Gutenberg Health Study.Cornea. 2014;33:359-65.
- 22. Nishitsuka K, Kawasaki R, Kanno M, et al. Determinants and risk factors for central corneal thickness in Japanese persons: the Funagata Study. Ophthalmic Epidemiol. 2011;18:244-49.
- 23. Teberik K, Eski MT, Doğan S, et al.Ocular abnormalities in morbid obesity. Arq Bras Oftalmol. 2019 Jan-Feb;82(1):6-11.
- 24. Badaró E, Novais E, Prodocimo LM, et al. Spectral-domain optical coherence tomography for macular edema. Scientific World Journal. 2014;2014:191847.
- 25. Sakata LM, Deleon-Ortega J, Sakata V, et al. Optical coherence tomography of the retina and optic nerve - a review. Clin Experiment Ophthalmol. 2009;37:90-9.
- 26. Wong AC, Chan CW, Hui SP. Relationship of gender, body mass index, and axial length with central retinal thickness using optical coherence tomography. Eye (Lond). 2005;19:292-97.
- 27. Hirooka K, Manabe S, Tenkumo K, et al. Use of the structure-function relationship in detecting glaucoma progression in early glaucoma. BMC Ophthalmol. 2014;14:118.
- 28. Zheng Y, Cheung CY, Wong TY, et al. Influence of height, weight, and body mass index on optic disc parameters. Invest Ophthalmol Vis Sci. 2010;51:2998-3002.
- 29. Jonas JB, Nangia V, Gupta R, et al. Retinal nerve fibre layer cross-sectional area, neuroretinal rim area and body mass index. Acta Ophthalmol. 2014;92:194-99.
- 30. R T Baran , S O Baran , N F Toraman , et al. Evaluation of intraocular pressure and retinal nerve fiber layer, retinal ganglion cell, central macular thickness, and choroidal thickness using optical coherence tomography in obese children and healthy controls. Niger J Clin Pract. 2019 Apr;22(4):539-545.
- 31. Demir S, Özer S, Alim S, et al. Retinal nerve fiber layer and ganglion-inner plexiform layer thickness in chidren with obesity. Int J Ophthalmol. 2016 Mar 18;9(3):434-8.
- 32. Zhu BD , Li SM, Li H, et al. Retinal nerve fiber layer thickness in a population of 12-year-old children in central China measured by iVue-100 spectral-domain optical coherence tomography: the Anyang Childhood Eye Study. Invest Ophthalmol Vis Sci. 2013;54:8104-11.
There are 32 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Ophthalmology |
| Journal Section | Research Article |
| Authors | |
| Early Pub Date | October 14, 2021 |
| Publication Date | January 1, 2022 |
| Submission Date | September 4, 2021 |
| Published in Issue | Year 2022Volume: 13 Issue: 1 |
